• 제목/요약/키워드: Micro-well array

검색결과 62건 처리시간 0.026초

주기적으로 배열된 회전하는 원형 실린더를 이용한 채널유동 토폴로지 변화 (CHANGE OF CHANNEL-FLOW TOPOLOGY BY A STREAMWISE-PERIODIC ARRAY OF ROTATING CIRCULAR CYLINDERS)

  • 정태경;양경수;이경준;강창우
    • 한국전산유체공학회지
    • /
    • 제18권4호
    • /
    • pp.17-24
    • /
    • 2013
  • In this study, we consider the characteristics of channel flow in the presence of an infinite streamwise array of equispaced identical rotating circular cylinders. This flow configuration can be regarded as a model representing a micro channel or an internal heat exchanger with cylindrical vortex generators. A numerical parametric study has been carried out by varying Reynolds number based on the bulk mean velocity and the cylinder diameter, and the gap between the cylinders and the channel wall for some selected angular speeds. An immersed boundary method was employed to facilitate implementing the cylinders on a Cartesian grid system. No-slip condition is employed at all solid boundaries including the cylinders, and the flow is assumed to be periodic in the streamwise direction. The presence of the rotating circular cylinders arranged periodically in the streamwise direction causes a significant topological change of the flow, leading to increase of mean friction on the channel walls. More quantitative results as well as qualitative physical explanations are presented to justify the effectiveness of rotating cylinders to modify flow topology, which might be used to enhance heat transfer on the channel walls.

Design and characterization of a compact array of MEMS accelerometers for geotechnical instrumentation

  • Bennett, V.;Abdoun, T.;Shantz, T.;Jang, D.;Thevanayagam, S.
    • Smart Structures and Systems
    • /
    • 제5권6호
    • /
    • pp.663-679
    • /
    • 2009
  • The use of Micro-Electro-Mechanical Systems (MEMS) accelerometers in geotechnical instrumentation is relatively new but on the rise. This paper describes a new MEMS-based system for in situ deformation and vibration monitoring. The system has been developed in an effort to combine recent advances in the miniaturization of sensors and electronics with an established wireless infrastructure for on-line geotechnical monitoring. The concept is based on triaxial MEMS accelerometer measurements of static acceleration (angles relative to gravity) and dynamic accelerations. The dynamic acceleration sensitivity range provides signals proportional to vibration during earthquakes or construction activities. This MEMS-based in-place inclinometer system utilizes the measurements to obtain three-dimensional (3D) ground acceleration and permanent deformation profiles up to a depth of one hundred meters. Each sensor array or group of arrays can be connected to a wireless earth station to enable real-time monitoring as well as remote sensor configuration. This paper provides a technical assessment of MEMS-based in-place inclinometer systems for geotechnical instrumentation applications by reviewing the sensor characteristics and providing small- and full-scale laboratory calibration tests. A description and validation of recorded field data from an instrumented unstable slope in California is also presented.

고정밀 회전 및 축방향 이송을 위한 신개념 원통형 자기부상 스테이지 (Novel Cylindrical Magnetic Levitation Stage for Rotation as well as Translation along Axles with High Precisions)

  • 전정우;;이창린;정연호;김종문;오현석;김성신
    • 전기학회논문지
    • /
    • 제61권12호
    • /
    • pp.1828-1835
    • /
    • 2012
  • In this paper, a conceptual design and a detailed design of novel cylindrical magnetic levitation stage is introduced. This is came from planar-typed magnetic levitation stage. The proposed stage is composed of cylinder-typed permanent magnet array and semi-cylinder-typed 3 phase winding module. When a proper current is induced at winding module, a magnetic levitation force between the permanent magnet array and winding module is generated. The proposed stage can precisely move the cylinder to rotations and translations as well as levitations with the magnetic levitation force. This advantage is useful to make a nano patterning on the surface of cylindrical specimen by using electron beam lithography under vacuum. Two methods are used to calculate required magnetic levitation forces. The one is 2D FEM analysis, the other is mathematical modeling. This paper shown that results of two methods are similar. An assistant plate is introduced to reduce required currents of winding module for levitations in vacuum. The mathematical model of cylindrical magnetic levitation stage is used for dynamic simulation of magnetic levitations. A lead-lag compensator is used for control of the model. Simulation results shown that the detail designed model of the cylindrical magnetic levitation stage with the assistant plate can be controlled very well.

Sensing Characterization of Metal Oxide Semiconductor-Based Sensor Arrays for Gas Mixtures in Air

  • Jung-Sik Kim
    • 한국재료학회지
    • /
    • 제33권5호
    • /
    • pp.195-204
    • /
    • 2023
  • Micro-electronic gas sensor devices were developed for the detection of carbon monoxide (CO), nitrogen oxides (NOx), ammonia (NH3), and formaldehyde (HCHO), as well as binary mixed-gas systems. Four gas sensing materials for different target gases, Pd-SnO2 for CO, In2O3 for NOx, Ru-WO3 for NH3, and SnO2-ZnO for HCHO, were synthesized using a sol-gel method, and sensor devices were then fabricated using a micro sensor platform. The gas sensing behavior and sensor response to the gas mixture were examined for six mixed gas systems using the experimental data in MEMS gas sensor arrays in sole gases and their mixtures. The gas sensing behavior with the mixed gas system suggests that specific adsorption and selective activation of the adsorption sites might occur in gas mixtures, and allow selectivity for the adsorption of a particular gas. The careful pattern recognition of sensing data obtained by the sensor array made it possible to distinguish a gas species from a gas mixture and to measure its concentration.

60 GHz 대역 능동 안테나 모듈 설계 (Active Antenna Module for 60 GHz Frequency Band)

  • 안세인;윤상원
    • 한국전자파학회논문지
    • /
    • 제30권6호
    • /
    • pp.518-521
    • /
    • 2019
  • 본 논문에서는 상용 트랜스미터 칩과 패치 어레이 안테나를 결합하여 60 GHz 대역에서 동작하는 능동 안테나 모듈을 설계, 제작하였다. 설계된 모듈은 안테나 PCB와 트랜스미터 칩이 장착된 송신 모듈 PCB가 결합되는 구조로 하였다. 주파수 제어신호 및 바이어스 제어신호는 아두이노 키트를 사용하여 인가하였으며, 기저대역의 I/Q 신호가 트랜스미터 칩으로 인가될 수 있도록 하였다. 송신 모듈의 출력은 단일 출력으로 안테나에 연결되므로 차동 출력을 내는 트랜스미터 칩의 출력을 링 하이브리드 발룬에 전달하고, 이를 초소형 상용 커넥터로 $2{\times}4$ 마이크로스트립 패치 어레이 안테나 PCB로 전달되도록 하였다. 최종 출력되는 밀리미터파 신호의 방사패턴 측정을 통하여 시뮬레이션 결과와 비교하는 방식으로 확인하였다. 제작된 능동 안테나 모듈의 방사패턴 측정 결과, 3 dB 빔폭과 null 포인트의 위치가 시뮬레이션 결과와 잘 일치함을 확인하였다.

정전 열 접합을 이용한 FED 스페이서의 초청정 정렬/탑재 공정 개발 (Development of Ultra-Clean Aligning/Mounting Process of FED Spacers using Electrostatic Bonding)

  • 주병권;강문식;이윤희
    • 대한전기학회논문지:전기물성ㆍ응용부문C
    • /
    • 제49권11호
    • /
    • pp.635-639
    • /
    • 2000
  • In this paper, a new idea about ultra-clean aligning and mounting method of FED spacers was introduced. The glass-to -glass electrostatic bonding process was employed in order to bond the micro-structures of spacers to black matrix area formed on an FED anode substrate. It is possible to get adhesive-free bonding interface and well-aligned spacer array on an FED anode substrate with a ${\pm}5{\mu}m$ accuracy. Finally, I inch-sized FED panel was demonstrated to make sure of its applicability to FED panel fabrication.

  • PDF

Simultaneous Quantitative Determination of Multiple Analytes with Fluorescence- Tagged Probes by Immunochromatogratphy

  • Jeong, Dong-Seok;Choi, Eui-Yul
    • Animal cells and systems
    • /
    • 제7권1호
    • /
    • pp.89-92
    • /
    • 2003
  • Immunoassays have become indispensable tools and achieved great importance in scientific and medical research. However, typical immunoassays are time-consuming and use complex, multi-step procedures. In this study, we introduce a new immunoassay system for the quantification of several analytes at a time without any washing steps. It is comprised of a detector solution with fluorescence-labeled antibodies and a test strip with immobilized capture antibodies. Using a micro-array scanner, the antigen-antibody complex was quantitatively determined by measuring the intensities of fluorescence on the capture lines or dots of nitrocellulose membrane. This method demonstrated its rapid quantitative determination of analytes without many processing steps as well as specific identification of multiple analytes in biological specimens.

Magnetic properties of micro-patterned array of anti-dots in Co/Ni bilayer

  • Deshpande, N.G.;Seo, M.S.;Zheng, H.Y.;Lee, S.J.;Rhee, J.Y.;Kim, K.W.;Lee, Y.P.
    • 한국진공학회:학술대회논문집
    • /
    • 한국진공학회 2010년도 제39회 하계학술대회 초록집
    • /
    • pp.276-276
    • /
    • 2010
  • Large-area micropatterned array of Co/Ni bilayer anti-dots was fabricated using photolithography and wet etching process. The surface morphology as well as the surface topography was checked by scanning electron microscopy and atomic force microscopy, whereas the magnetic properties were studied by magneto-optical Kerr effect (MOKE) and magnetic force microscopy (MFM). Systematic studies of the magnetic-reversal mechanism, the in-plane anisotropy and the switching field properties were carried out. To get a comprehensive knowledge about the domain configuration, we also employed OOMMF simulations. It was found from the MOKE measurements that a combined effect of configurational and the magneto-crystalline anisotropy simultaneously works in such micropatterned bilayer structures. In addition, the inclusion of holes in the uniform magnetic film drastically affected the switching field. The MFM images show well-defined domain structures which are periodic in nature. The micromagnetic simulations indicate that the magnetization reversal of such a structure proceeds by formation and annihilation of domain walls, which were equally manifested by the field-dependent MFM images. The observed changes in the magnetic properties are strongly related to both the patterning that hinders the domain-wall motion and to the magneto-anisotropic bilayered structure.

  • PDF

대면적 미세 성형공정 원천기술 개발 (Development of Key Technologies for Large Area Forming of Micro Pattern)

  • 최두선;유영은;윤재성;제태진;박시환;이우일;김봉기;정은정;김진상
    • 한국정밀공학회지
    • /
    • 제28권7호
    • /
    • pp.777-782
    • /
    • 2011
  • Micro features on the surface are well-known to have significant effects on optical or mechanical properties such as the optical interference, reflectance at the surface, contact angle, interfacial friction, etc. These surface micro features are increasingly employed to enhance the functionality of the applications in various application areas such as optical components for LCD or solar panel. Diverse surface features have been proposed and some of them are showing excellent efficiency or functionality, especially in optical applications. Most applications employing the micro features need manufacturing process for mass production and the injection molding and roll-to-roll forming, which are typical processes for mass production adopting polymeric materials, may be also preferred for micro patterned plastic product. Since the functionality or efficiency of the surface structures generally depends on the shape and the size of the structure itself or the array of the structures on the surface, it would be very important to replicate the features very precisely as being designed during the molding the micro pattern applications. In this paper, a series of research activities is introduced for roll-to-roll forming of micro patterned film including filling of patterns with UV curable resin, demolding of surface structures from the roll tool, control of surface energy and cure shrinkage of resin and dispose time and intensity of the UV light for curing of UV curable resin.

Ginsenoside Rh2 upregulates long noncoding RNA STXBP5-AS1 to sponge microRNA-4425 in suppressing breast cancer cell proliferation

  • Park, Jae Eun;Kim, Hyeon Woo;Yun, Sung Hwan;Kim, Sun Jung
    • Journal of Ginseng Research
    • /
    • 제45권6호
    • /
    • pp.754-762
    • /
    • 2021
  • Background: Ginsenoside Rh2, a major saponin derivative in ginseng extract, is recognized for its anti-cancer activities. Compared to coding genes, studies on long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) that are regulated by Rh2 in cancer cells, especially on competitive endogenous RNA (ceRNA) are sparse. Methods: LncRNAs whose promoter DNA methylation level was significantly altered by Rh2 were screened from methylation array data. The effect of STXBP5-AS1, miR-4425, and RNF217 on the proliferation and apoptosis of MCF-7 breast cancer cells was monitored in the presence of Rh2 after deregulating the corresponding gene. The ceRNA relationship between STXBP5-AS1 and miR-4425 was examined by measuring the luciferase activity of a recombinant luciferase/STXBP5-AS1 plasmid construct in the presence of mimic miR-4425. Results: Inhibition of STXBP5-AS1 decreased apoptosis but stimulated growth of the MCF-7 cells, suggesting tumor-suppressive activity of the lncRNA. MiR-4425 was identified to have a binding site on STXBP5-AS1 and proven to be downregulated by STXBP5-AS1 as well as by Rh2. In contrast to STXBP5-AS1, miR-4425 showed pro-proliferation activity by inducing a decrease in apoptosis but increased growth of the MCF-7 cells. MiR-4425 decreased luciferase activity from the luciferase/STXBP5-AS1 construct by 26%. Screening the target genes of miR-4425 and Rh2 revealed that Rh2, STXBP5-AS1, and miR-4425 consistently regulated tumor suppressor RNF217 at both the RNA and protein level. Conclusion: LncRNA STXBP5-AS1 is upregulated by Rh2 via promoter hypomethylation and acts as a ceRNA, sponging the oncogenic miR-4425. Therefore, Rh2 controls the STXBP5-AS1/miR-4425/RNF217 axis to suppress breast cancer cell growth.