• 로봇학회논문지
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• 제18권1호
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• pp.117-121
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• 2023

Research on walking assistance exoskeletons that provide optimized torque to individuals has been conducted steadily, and these studies aim to help users feel stable when walking and get help that suits their intentions. Because exoskeleton auxiliary efficiency evaluation is based on metabolic cost savings, experiments on real people are needed to evaluate continuously evolving control algorithms. However, experiments with real people always require risks and high costs. Therefore, in this study, we intend to actively utilize human musculoskeletal simulation. First, to improve the accuracy of musculoskeletal models, we propose a body segment mass distribution algorithm using body composition analysis data that reflects body characteristics. Secondly, the efficiency of most exoskeleton torque control algorithms is evaluated as the reduction rate of Metabolic Cost. In this study, we assume that the torque minimizing the Metabolic Cost is the optimal torque and propose a method for obtaining the torque.

• Physical Therapy Rehabilitation Science
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• 제13권2호
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• pp.152-162
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• 2024

Objective: This study was conducted to analyze the effect of wearable Electromyography-controlled functional electrical stimulation (EMG-controlled FES) System on Gait Function and cardiopulmonary metabolic efficiency during walking in older adults. Design: Cross-section study Methods: Total 22 older adult participants suitable to selection criteria of this study participated in this study. The EMG-controlled FES System, which functions as a wearable physical activity assist FES system was used. All participations performed randomly assigned two conditions (Non-FES assist [NFA], FES assist [FA]) of walking. In all conditions, spatio-temporal parameters and kinematics and kinetics parameters during walking was collected via 3D motion capture system and 6 minutes walking test (6MWT) and metabolic cost during walking and stairs climbing was collected via a portable metabolic device (COSMED K5, COSMED Srl, Roma, Italy). Results: In Spatio-temporal parameters aspects, The EMG-controlled FES system significantly improved gait functions measurements of older adults with sarcopenia at walking in comparison to the NFA condition (P<0.05). Hip, knee and ankle joint range of motion increased at walking in FA condition compared to the NFA condition (P<0.05). In the FA condition, moment and ground reaction force was changed like normal gait during walking of older adults in comparison to the NFA condition (P<0.05). The EMG-controlled FES system significantly reduced net cardiopulmonary metabolic energy cost, net energy expenditure measurement at stairs climbing (P<0.05). Conclusions: This study demonstrated that EMG-controlled FES is a potentially useful gait-assist system for improving gait function by making joint range of motion and moment properly.

• 한국실천공학교육학회논문지
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• 제2권1호
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• pp.146-153
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• 2010

ET 헬스기구에서 적용되는 이론은 공학교육에 좋은 예제가 될 수 있다. 물리교육학적 고찰에 의한 역학적 및 열적 에너지 소비량을 측정하여 에너지 소비량과 근육활성도의 관계, 운동량과 에너지 소비량의 관계, 그리고 에너지 소비량과 대사 소비량의 관계를 알아보았다. 에너지 소비량과 근육활성도의 조사에서 단시간동안 체중감량을 위해서는 고속으로 운동하는 것이 효과적이지만 근육활성도를 높여 기초 대사량을 높이기 위해서는 저속도 운동이 효과적이었다. 운동량과 유산소 에너지 소비량의 조사에서는 ET를 사용하여 유산소운동을 할 경우 효과가 높음을 알 수 있었고 유산소운동을 함으로써 체중을 줄이는 것이 효과적임을 알 수 있었다. 에너지 소비량과 대사 소비량의 조사에서는 고속으로 ET운동하여 체중은 더 줄어든다 하더라도 역학적에너지 소비율은 저속일 때와 별로 차이가 없었다.

• 한국임상수의학회지
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• 제16권2호
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• pp.428-438
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• 1999

A study was conducted to estimate cost of major dairy cattle diseases. Forty (n=40) of the 167 dairy herds in Gyeongnam (Chinju) area were stratified and selected randomly for participation in the national animal health monitoring system. Gyeongsnag University veterinarians, Gyeongnam Livestock Promotion Institute veterinarians and clinic veterinarian visited each herd once a month for a total periods of 12 months. At a each visit data on disease, production, management, finance, treatments, preventive activities, animal events, and any other relevant events were collected. Monthly and annual cost estimates of disease treatment were in computed in each herd and stratum(including cost of prevention). Results were expressed as cost per head and given separately for cows, young stock, and calves. In cows, the most expensive seven diseases entities (from the most to the least) were : (1) clinical mastitis; (2) breeding problems; (3)gastrointestinal problems; (4) multiple system problem; (5) birth problems; (6) metabolic/nutritional disease; (7) lameness. In young stock, the most costly disease were the multiple system problems, breeding problems, respiratory disease, gastrointestinal disease, and lameness. In calves, the most costly disease problems were gastrointestinal problems, respiratory disease, integumental, multiple system problems, and metabolic/nutritional problems.

• Journal of Preventive Medicine and Public Health
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• 제48권4호
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• pp.180-187
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• 2015

Objectives: Metabolic syndrome is an important etiologic factor in the development of certain types of cancers. The economic cost of the treatment of cancer has been steadily increasing. We therefore estimated the economic burden of cancers attributable to metabolic syndrome in Korea. Methods: We reviewed metabolic syndrome-related cancers and relative risk and then calculated population attributable fractions. We analyzed insurance claims data for metabolic syndrome-related cancers in 2012 in order to estimate the direct costs associated with these cancers, including hospitalization, outpatient visits, transportation costs, and caregivers' costs as well as indirect costs such as loss of productivity due to cancer treatment and premature death. Results: In 2012, 18 070 patients in Korea had cancers attributable to metabolic syndrome. The economic burden was USD 199.8 million and the direct and indirect costs were USD 124.5 million and USD 75.3 million, respectively. Conclusions: We estimated the economic burden of cancers attributable to metabolic syndrome in Korea and the efforts are necessary to reduce this burden.

• 한국전자통신학회논문지
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• 제8권12호
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• pp.1941-1948
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• 2013

본 연구는 우리나라 주간근로자의 건강증진 실천행위와 대사증후군과의 관계를 알아보고, 추후 대사증후군 환자의 건강증진 실천행위의 중요성을 제시하고자 실시하였다. 국민건강영양조사 제5기 1차년도 자료 중 주간근로자 1,034명을 대상으로 하였다. 연구결과 우리나라 주간근로자의 대사증후군은 연령이 증가할수록, 교육수준이 낮을수록, 흡연할수록 유의하게 높았고, 건강증진 실천행위 수가 증가할수록 대사증후군의 유병률이 낮아졌다는 결과를 얻었다. 주간근로자의 대사증후군을 관리 예방하기 위해서는 저비용, 고효율적 중재방법인 적절한 생활습관을 중재하는 것이 효과적이라고 사료된다.

• 한국생명과학회:학술대회논문집
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• 한국생명과학회 2005년도 제45회 학술심포지움 및 추계학술대회
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• pp.123-123
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• 2005

• Journal of Obesity & Metabolic Syndrome
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• 제27권4호
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• pp.203-212
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• 2018

Dynamic energy balance can give clinicians important answers for why obesity is so resistant to control. When food intake is reduced for weight control, all components of energy expenditure change, including metabolic rate at rest (resting energy expenditure [REE]), metabolic rate of exercise, and adaptive thermogenesis. This means that a change in energy intake influences energy expenditure in a dynamic way. Mechanisms associated with reduction of total energy expenditure following weight loss are likely to be related to decreased body mass and enhanced metabolic efficiency. Reducing calorie intake results in a decrease in body weight, initially with a marked reduction in fat free mass and a decrease in REE, and this change is maintained for several years in a reduced state. Metabolic adaptation, which is not explained by changes in body composition, lasts for more than several years. These are powerful physiological adaptations that induce weight regain. To avoid a typically observed weight-loss and regain trajectory, realistic weight loss goals should be established and maintained for more than 1 year. Using a mathematical model can help clinicians formulate advice about diet control. It is important to emphasize steady efforts for several years to maintain reduced weight over efforts to lose weight. Because obesity is difficult to reverse, clinicians must prioritize obesity prevention. Obesity prevention strategies should have high feasibility, broad population reach, and relatively low cost, especially for young children who have the smallest energy gaps to change.

• 대한유전성대사질환학회지
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• 제23권2호
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• pp.1-7
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• 2023

유전성 대사질환은 생화학적 대사 이상에 의해 발생하는 질환 군으로, 매우 다양할 뿐만 아니라 임상 양상이 서로 겹칠 수 있어 진단에 어려움을 겪을 수 있다. 과거에는 유전성 대사질환의 원인이 될 수 있는 유전자를 선정한 후 한 개씩 분석하는 방식으로 유전자 검사를 시행했다. 하지만, 최근에는 차세대 염기서열분석 기술이 발전함에 따라 유전성 대사질환과 관련된 수백-수천개의 유전자를 한꺼번에 분석하거나, 인간의 모든 유전자를 포함하는 엑솜/게놈 분석을 시행한 후 원인 유전자를 찾는 방식으로 유전 진단의 패러다임이 바뀌고 있다. 본 종설에서는 차세대 염기서열분석을 이용한 유전성 대사질환의 유전 진단 방법과 진단율 및 주의점 등을 살펴보고자 한다.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.328-328
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• 2017

Drought is a major limiting factor that reduces rice production and occurs often especially under recent climate change. Plants have the ability to alter their developmental morphology in response to changing environment, which is known as phenotypic plasticity. In our previous studies, we found that one chromosome segment substitution line (CSSL50 derived from Nipponbare and Kasalath crosses) showed no differences in shoot and root growth as compared with the recurrent genotype, Nipponbare under non-stress condition but showed greater growth responses compared with Nipponbare under mild drought stress condition. We hypothesized that reducing root respiration as metabolic cost, which may be largely a consequence of aerenchyma formation would be one of the key mechanisms for root plasticity expression. This study aimed to evaluate the root respiration and aerenchyma formation under various soil moisture conditions among genotypes with different root plasticity. CSSL50 together with Nipponbare and Kasalath were grown under waterlogged conditions (Control) and mild drought stress conditions (20% of soil moisture content) in a plastic pot ($11cm{\times}14cm$, ${\varphi}{\times}H$) and PVC tube ($3cm{\times}30cm$, ${\varphi}{\times}H$). Root respiration rate was measured with infrared gas analyzer (IRGA, GMP343, Vaisala, Finland) with a closed static chamber system. There was no significant difference between genotypes in control for shoot and root growth as well as root respiration rate. In contrast, all the genotypes increased their root respiration rates in response to mild drought stress. However, CSSL50 showed lower root respiration rate than Nipponbare, which was associated by higher root aerenchyma formation that was estimated based on internal gas space (porosity) under mild drought stress conditions. Furthermore, there were significant negative correlations between root length and root respiration rate. These results imply that reducing the metabolic cost (= root respiration rate) is a key mechanism for root plasticity expression, which CSSL50 showed under mild drought.