• Title/Summary/Keyword: Meta-Research

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Two Ways of Doing Cross-disciplinary Philosophy of Science Research: Inter-disciplinary STS and Multi-disciplineary STS (학제간 과학철학 연구의 두 방향: 간학문 STS와 다학문 STS)

  • Yi Sang-Wook
    • Journal of Science and Technology Studies
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    • v.5 no.2 s.10
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    • pp.1-21
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    • 2005
  • It has been a point of dispute how to define the disciplinary identity of STS; science and technology studies or science, technology and society? Still, STS is now emerging as an autonomous research discipline with its own agendas and styles of reasoning from a mere collections of various meta disciplines such as philosophy of science, history of science and sociology of science. The paper discusses how philosophy of science in its cross-disciplineary mode can contribute to STS (understood as science and technology studies) research given these recent academic trends. We can start from the observation that there are two distinctive ways of doing cross-disciplinary research: inter-disciplinary and multi-disciplinary. Then it is shown with concrete examples how philosophy of science can productively participate in both ways of cross-disciplinary researches in STS.

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A Study on Recent Research Trend on Web Accessibility Evaluation in Korea (한국의 웹 접근성 평가 연구동향 분석)

  • Kim, MiJeong;Kim, JaMee
    • KIPS Transactions on Software and Data Engineering
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    • v.7 no.1
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    • pp.33-42
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    • 2018
  • The purpose of this study is to suggest the shortcomings and the direction of the web accessibility evaluation studies by analyzing the research trends on web accessibility evaluation in Korea. For this aim, a total of 59 theses presented in the registered academic journal and the candidate of registration academic journals from January 2000 to March 2017 were selected. The selected dissertations have been analyzed based on the evaluators, the evaluation targets, the evaluation methods, and the evaluation results with regard to web accessibility. As a result of the analysis, the highest rate in the evaluator aspect was 'independent evaluation (66 percent)' and the highest percentage in the evaluation target aspect was 'web site (83 percent)'. When it came to the evaluation methods, automatic evaluation and the mixture of automatic evaluation and manual evaluation had a similar percentage. Lastly, only two papers showed that web accessibility did not have any problems. This study is meaningful in the sense that it suggested a desirable direction for the web accessibility studies in Korea and web accessibility evaluation studies in the situation when the meta studies which analyzed research trends are insufficient.

Topic and Survey Methodological Trends in 'The Journal of Information Systems' ('정보시스템연구'의 연구주제와 서베이 방법론 동향분석)

  • Ryoo, Sung-Yul;Park, Sang-Cheol
    • The Journal of Information Systems
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    • v.27 no.4
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    • pp.1-33
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    • 2018
  • Purpose The purpose of this study is to review topic and survey methodological trends in 'The Journal of Information Systems' in order to present the practical guidelines for the future IS research. By attempting to conduct a meta-analysis on both topic and survey methodological trends, this study could provide researchers wishing to pursue this line of work further with what can be done to improve IS disciplines. Design/methodology/approach In this study, we have reviewed 185 papers that were published in 'The Journal of Information Systems' from 2010 to 2018 and classified them based on topics studied and survey methodologies used. The classification guidelines, which was developed by Palvia et al.(2015), has been used to capture the topic trends. We have also employed Struab et al.(2004)s' guidelines for securing rigor of validation issues. By using two guidelines, this study could also present topic and rigor trends in 'The Journal of Information Systems' and compare them to those trends in International Journals. Findings Our findings have identified dominant research topics in 'The Journal of Information Systems'; 1) social media and social computing, 2) IS usage and adoption, 3) mobile computing, 4) electronic commerce/business, 5) security and privacy, 6) supply chain management, 7) innovation, 8) knowledge management, and 9) IS management and planning. This study also could offer researchers who pursue this line of work further practical guidelines on mandatory (convergent and discriminant validity, reliability, and statistical conclusion validity), highly recommended (common method bias testing), and optional validations (measurement invariance testing for subgroup analysis, bootstrapping methods for testing mediating effects).

Hycanthone Inhibits Inflammasome Activation and Neuroinflammation-Induced Depression-Like Behaviors in Mice

  • Kyung-Jun, Boo;Edson Luck, Gonzales;Chilly Gay, Remonde;Jae Young, Seong;Se Jin, Jeon;Yeong-Min, Park;Byung-Joo, Ham;Chan Young, Shin
    • Biomolecules & Therapeutics
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    • v.31 no.2
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    • pp.161-167
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    • 2023
  • Despite the various medications used in clinics, the efforts to develop more effective treatments for depression continue to increase in the past decades mainly because of the treatment-resistant population, and the testing of several hypotheses- and target-based treatments. Undesirable side effects and unresponsiveness to current medications fuel the drive to solve this top global health problem. In this study, we focused on neuroinflammatory response-mediated depression which represents a cluster of depression etiology both in animal models and humans. Several meta-analyses reported that proinflammatory cytokines such as interleukin 6 (IL-6) and tumor necrosis factor-α (TNF-α) were increased in major depressive disorder patients. Inflammatory mediators implicated in depression include type-I interferon and inflammasome pathways. To elucidate the molecular mechanisms of neuroinflammatory cascades underlying the pathophysiology of depression, we introduced hycanthone, an antischistosomal drug, to check whether it can counteract depressive-like behaviors in vivo and normalize the inflammation-induced changes in vitro. Lipopolysaccharide (LPS) treatment increased proinflammatory cytokine expression in the murine microglial cells as well as the stimulation of type I interferon-related pathways that are directly or indirectly regulated by Janus kinase-signal transducer and activator of transcription (JAK-STAT) activation. Hycanthone treatment attenuated those changes possibly by inhibiting the JAK-STAT pathway and inflammasome activation. Hycanthone also ameliorated depressive-like behaviors by LPS. Taken together, we suggest that the inhibitory action of hycanthone against the interferon pathway leading to attenuation of depressive-like behaviors can be a novel therapeutic mechanism for treating depression.

Research on Urban Air Mobility Operations Optimization Research Trends (도심항공교통(Urban Air Mobility) 운영 최적화 연구 동향에 관한 연구)

  • Jibok Chung
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.3
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    • pp.701-706
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    • 2023
  • The Korean government and industry have presented a roadmap for the commercialization of UAM services and are promoting it in earnest. In order to introduce full-scale UAM services, there are various issues to be solved, such as the development of high-performance aircraft, the design of network bases and corridors, the optimization of operation management, and the establishment of related laws and systems. In this study, in terms of optimizing operation management, we will examine research trends by field, focusing on Korea, and derive research topics that need to be solved in the future. Korean researchers have suggested that research is centered on UAM service usage fees, usage intentions and acceptance models, and vertiport location selection, but operational optimization studies such as service order acceptance, aircraft repositioning, and battery charging and maintenance scheduling are needed in the future.

Korean Information Summary System for National R&D Projcet Information Summary (국가R&D과제정보 요약을 위한 한국어 정보요약 시스템)

  • Lee, Jong-Won;Kim, Tae-Hyun;Shin, Dong-Gu;Jo, Woo-Seung
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2022.10a
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    • pp.72-74
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    • 2022
  • The National Science and Technology Knowledge Information Service (NTIS) provides information on national R&D projects. Project information consists of meta-information such as 'project name', 'project performance institution', 'research manager name', and text explaining projects such as 'research goal', 'research content', and 'expected effect'. There is a problem that it takes a lot of time to find the desired project information by checking all of the "research goals" or "research contents" in the list of results of searching for 1 million project information. To solve this problem, this paper proposes a project information summary system that summarizes the parts consisting of long texts within the national R&D project information. By analyzing the linguistic characteristics of the Korean language, a preprocessor was built and a project information summary model based on natural language processing technology was developed to process preprocessed text information. Through this, project information composed of long sentences is provided in a compressed and summarized form, which will help users to easily and quickly infer the overall content with the summary information alone.

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Characteristics of Middle School Students in a Biology Special Class at Science Gifted Education Center: Self-regulated Learning Abilities, Personality Traits and Learning Preferences (과학영재교육원 생물반 중학생들의 특성: 자가조절학습능력에 따른 개인적 성향 및 학습선호도)

  • Seo, Hae-Ae
    • Journal of Gifted/Talented Education
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    • v.19 no.3
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    • pp.457-476
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    • 2009
  • The research aimed to investigate characteristics of middle school students in a biology class as science gifted education in terms of self-regulated learning abilities, personality traits and learning preferences. The twenty subject in the study responded to questionnaires of a self-regulated learning ability instrument, a personality trait tool, and a learning preference survey in March, 2009. It was found that the research subjects showed higher levels of cognitive strategies, meta-cognition, and motivation than those students in a previous study(Jung et. al., 2004), while environment was opposite. The level of cognitive strategies was significantly correlated with meta-cognition(r=.610, p=.004) and motivation (r=.538, p=.014) and meta-cognition with environment(r=.717, p=.000). Those students who showed highest levels of self-regulated learning ability displayed various personality traits. One male student with the highest level of self-regulated learning ability showed a personality of hardworking, tender-minded, and conscientious traits and wanted to be a medical doctor. The female student with the second highest level of self-regulated learning ability presented a personality as creative, abstract and divergent thinker and she showed a strong aspiration to be a world-famous biologist with breakthrough contribution. The five students with highest levels of self-regulated learning ability showed a common preference in science learning: they dislike memory-oriented and theory-centered lecture with note-taking from teacher's writings on chalkboard; they prefer science learning with inquiry-oriented laboratory work, discussion among students as well as teachers. However, reasons to prefer discussion were diverse as one student wants to listen other students' opinions while the other student want to present his opinion to other students. The most favorable science teachers appeared to be who ask questions frequently, increase student interests, behave friendly with students, and is a active person. In conclusion, science teaching for the gifted should employ individualized teaching strategies appropriate for individual personality and preferred learning styles as well as meeting with individual interests in science themes.

Efficacy and Safety of COVID-19 Vaccines in Adolescents: Systematic Review of Randomized Controlled Studies and Observational Studies

  • Soo-Han Choi;Su-Yeon Yu;Jimin Kim;Miyoung Choi;Youn Young Choi;Jae Hong Choi;Ki Wook Yun;Young June Choe
    • Pediatric Infection and Vaccine
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    • v.31 no.1
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    • pp.12-24
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    • 2024
  • The number of pediatric coronavirus disease 2019 (COVID-19) cases worldwide are increasing compared to the early phase of the pandemic, along with highly transmissible severe acute respiratory syndrome coronavirus variant and the increase in adult COVID-19 vaccination. We conducted a rapid systematic review and meta-analysis of published randomized clinical trials (RCTs) of the COVID-19 vaccines and the observational retrospective studies on adverse events after COVID-19 vaccination in adolescents. Seventeen studies were finally included in this systematic review. Meta-analysis showed that although vaccination in adolescents was significantly effective to prevent COVID-19 infection in retrospective studies (risk ratio [RR], 0.29; 95% confidence interval [CI], 0.22-0.37; I2 =100%), however the effect of preventing COVID-19 infection was lower than in RCTs (RR, 0.05; 95% CI, 0.01-0.27). In five retrospective studies, the pooled estimated proportion of participants with myocarditis and/or pericarditis was 2.33 per 100,000 of the population (95% CI, 0.97-5.61 per 100,000). Sub-group analysis with sex and vaccine doses showed that male (5.35 per 100,000) and the second dose (9.71 per 100,000) had significantly higher incidence of myocarditis and/or pericarditis than female (1.09 per 100,000) and the first dose (1.61 per 100,000), respectively. Our study showed that mRNA COVID-19 vaccines in adolescent recipients were favorable and effective against COVID-19 in RCT as well as observational studies. The safety findings of BNT162b2 vaccine in adolescents were explored and we found the difference of safety according to sex and vaccine doses. The occurrence of adverse events after mRNA COVID-19 vaccination should be monitored.

Qualitative Meta-analysis on Students' Understanding of Earth Science Concepts from the Perspective of Collective PCK: Focusing on the Concepts of Greenhouse Effect, Global Warming, and Climate Change (집단적 PCK 관점에서 학생들의 지구과학 개념 이해에 대한 질적 메타 분석: 온실 효과, 지구 온난화, 기후변화 개념을 중심으로)

  • Kwon Jung Kim;Eui Seon Choi;Ho Jun Kim;Jae Yong Park;Ki Young Lee
    • Journal of the Korean earth science society
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    • v.45 no.3
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    • pp.239-259
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    • 2024
  • In this study, a qualitative meta-analysis was conducted on research papers on earth science education to derive knowledge of students' understanding of specific science topics-greenhouse effect, global warming, and climate change-within the context of collective Pedagogical Content Knowledge (PCK). Twenty-two research papers addressing students' alternative conceptions (misconceptions) about these topics were selected and analyzed for their respective definitions, causes (mechanisms), and impacts. Semantic network analysis and a mental model framework were applied to synthesize the findings. The meta-analysis revealed several key insights: (1) Regarding the greenhouse effect, students often used the terms "greenhouse effect" and "global warming" interchangeably, lacked knowledge about the types of greenhouse gases, and misunderstood their roles. They commonly associated the greenhouse effect with environmental pollution or changes in the ozone layer, failing to recognize its relation to the heat balance between the surface and atmosphere. (2) Concerning global warming, students confused it with sea level rise and linked it to pollution, ozone layer changes, and glacier melting. They understood global warming as a disruption of the heat balance between the surface and atmosphere but had misconceptions about its environmental impacts. (3) In terms of climate change, students used the term interchangeably with global warming, weather change, and climate anomalies. They associated climate change with atmospheric pollution and ozone layer depletion but misunderstood its environmental impacts. As result, three mental models-categorical, mechanistic, and hierarchical misconceptions-were identified as collective PCK. The implications for enhancing earth science teachers' PCK were discussed based on these findings.

Mineralogy and Mineral-chemistry of REE Minerals Occurring at Mountain Eorae, Chungju (충주 어래산 일대에서 산출하는 희토류 광물의 광물학적 및 광물화학적 특성)

  • You, Byoung-Woon;Lee, Gill Jae;Koh, Sang Mo
    • Economic and Environmental Geology
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    • v.45 no.6
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    • pp.643-659
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    • 2012
  • The Chungju Fe-REE deposit is located in the Kyemyeongsan Formation of the Ogcheon Group. The Kyemyeongsan Formation includes meta-volcanic rocks and pegmatite hosted REE deposit which show different kind of REE-containing minerals. The meta-volcanic rocks hosted REE deposits' main REE minerals are allanite, zircon, apatite, and sphene, whereas the pegmatite hosted REE deposits is mainly composed of fergusonite, and karnasurtite, zircon, thorite. The meta-volcanic rock hosted major REE mineral is allanite as the form of aggregation and contains 23.89-29.19 wt% TREO (Total Rare Earth Oxide), 4.71-9.92 wt% $La_2O_3$, 11.30-14.33 wt% $Ce_2O_3$, 0.11-0.29 wt% $Y_2O_3$, 0.15-0.94 wt% $ThO_2$, as a formula of (Ca, Y, REE, Th)$_{2.095}$(Mg, Al, Ti, Mn, $Fe^{3+})_{2.770}(SiO_4)_{2.975}(OH)$. Accompanying REE in a coupled substitution for $Ca^{2+}$ (M1 site) and $Al^{3+}-Fe^{2+}$ (M2 site) leads to a large chemical variety. Due to the allanite's high contents of Fe, it belongs to Ferrialanite. The pegmatite hosted deposit's domi-nant REE mineral is fergusonite as prismatic or subhedral grains associated with zircon, fluorite and karnasurtite. Geochemical composition of the fergusonite($YNbO_4$) suggests substitution of Y-REE and Y-Th in A-site, and Nb-Ta-Ti in B-site, furthermore the proportion of $Y_2O_3$ and $Nb_2O_5$ is oddly 1:1.5 comparing to the ideal ratio 1:1 and Nb is higher than Y, also A-site Y actively substitutes with REE. Karnasurtite in pegmatite variously ranges 9.16-22.88 wt% $Ce_2O_3$, 2.15-9.16 wt% and $La_2O_3$, 0.44-10.8 wt% $ThO_2$, as a calculated formula (Y, REE, Th, K, Na, Ca)$_{1.478}(Ti, Nb)_{1.304}$(Mg, Al, Mn, $Fe^{3+})_{0.988}$(Si, P)$_{1.431}O_7(OH)_4{\cdot}3H_2O$. Firstly the 870-860 Ma is the initial age of the supercontinent Rhodinia dispersal and subsequent A-1 type volcanism, which contains Fe, REE, and HFS(High Field Strength elements; Nb, Zr, Y etc.) elements in Fe-rich meta-volcanic rocks dominant Kyemyeongsan Formation, might mineralized allanite. Another synthesis is that regional metamorphism at late Paleozoic 300-280 Ma(Cho et al., 2002) might cause allanite mineralization. Also pegmatite REE mineralization highly related to the granite intrusion over the Chungju area in Jurassic(190 Ma; Koh et al., 2012). Otherwise above all, A-1 type volcanism at the same time of the Kyemyeongsan Formation development, regional metamorphism and pegmatite, might have caused REE mineralization. Although REE ore bodies display a close spatial association, each ore bodies display temporal distinction, different mineral assemblage and environment of ore formation.