• The Journal of Internal Korean Medicine
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• v.45 no.4
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• pp.549-567
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• 2024

Objectives: This study was aimed at evaluating the effectiveness and safety of Danggui buxue decoction (DBD) for iron deficiency anemia (IDA) by systematic review and meta-analysis of the randomized controlled trials (RCTs). Methods: Randomized controlled trials on the treatment of DBD for IDA patients were selected from among the literature published from the beginning of each database to May 30, 2023 in nine domestic and foreign databases (PubMed, EMBASE, Cochrane, Chinese Academic Journals (CAJ), CiNii Research, J-STAGE, Oriental Medicine Advanced Searching Integrated System (OASIS), Research Information Sharing Service (RISS), and ScienceON). The quality of the literature was evaluated using the Cochrane ROB tool 2.0 (ROB2) and GRADE method. The meta-analysis was conducted using RevMan5.4. Results: A total of 636 patients with IDA were finally selected from the 7 RCTs. The meta-analysis showed that the treatment groups that underwent both DBD and conventional treatment were statistically higher than the control groups that performed only conventional treatment in all indicators that showed effectiveness of DBD such as red blood cell (mean difference (MD) 0.38×10¹²/L, 95% CI: 0.16-0.60), hemoglobin (MD 12.45 g/L, 95% CI: 10.27-14.63), serum ferritin (MD 3.50 ㎍/L, 95% CI: 1.71-5.29), and total effective rate (relative risk (RR) 1.13, 95% CI: 1.05-1.21). The incidence of adverse events was 0.39 times lower in the DBD group than in the conventional group (RR 0.39, 95% CI: 0.22-0.70). Conclusion: This study demonstrated the effectiveness and safety of DBD with conventional treatment and further provided a basis for administering DBD to patients with IDA in clinical treatment.

• The Journal of the Korea Contents Association
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• v.14 no.1
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• pp.209-222
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• 2014

The purpose of this study was to discuss the papers of social welfare field that were published in Korea, from a research methodology aspect in accordance with the meta-analysis reporting standard proposed by the United States Psychological Association. To this end, an analysis was conducted according to 5 types of conformity (title and abstract, introduction, methods, results and discussion) on the target subjects of 26 meta-analysis papers of social welfare field. The analysis results showed, first, the conformity in the title and abstract showed good results except for the suggested topics for meta-analysis methods. Second, in terms of the conformity of the introduction, the descriptions seemed to be good in a number of items. Third, for the conformity in the methods, the overall reporting standard was seen to be lacking and, in particular, the reporting standard for the coding procedure was seen as being very deficient. Fourth, the conformity in the results showed that the assessment of research quality and the magnitude of efficacy for each individual study, sample size, and the contents of the provided tables, summary of tables and graphs, including the study results, were not being properly reported. Fifth, the conformity in discussions was seen to be generally sound. Based on such results, by providing a reporting standard and perspective needed for ensuring feasibility that can be used to assess meta-analysis study materials, this study was aimed at presenting implications for the academic advancement of field of social welfare.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.7567-7573
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• 2015

Background: Catastrophic effects of mustard gas as a chemical warfare agent have always been a major problem for those exposed to this agent. In this meta-analysis it was tried to evaluate carcinogenesis, ocular, cutaneous and respiratory complications of mustard gas exposure among Iranians who had been exposed to this agent during the Iran-Iraq war. Materials and Methods: In this meta-analysis, the required data were collected using keywords "mustard gas", "sulfur mustard", "cancer", "neoplasm", "respiratory complications", "ocular complications", "lung disease", "chronic complication", "eye", "skin", "cutaneous complication", "carcinogenesis" and their combination with keywords "Iran", "Iranian", "prevalence", "mortality" and their Farsi equivalent terms from the databases of SID, Iranmedex, Magiran, Pubmed, Science Direct, Google Search engine, Gray Literature and Reference of References. To determine the prevalence of each complication and perform meta-analysis, CMA: 2 (Comprehensive Meta-Analysis) software with a randomized model was used. Results: Of the 542 articles found, 7 national articles, consistent with the aims of this study were selected. Meta-analysis of seven papers revealed that cancer risk, especially cancer of the respiratory system was elevated, so that the relative risk (RR) of cancer role of mustard gas was inconsistent from 2/1 to 4 in this survey. Also prevalence of delayed skin disorders due to sulfur mustard was 94.6%, pulmonary complications 94.5% and ocular complications 89.9%. The incidence of various cancers in victims exposed to mustard gas was 1.7% worldwide where the rate was 2.2% in Iranian victims of the Iraq-Iran war. Conclusions: Based on present study the prevalence of delayed mustard gas related cutaneous, pulmonary and ocular complications is above 90% and risk of carcinogenesis is higher in comparison to worldwide statistics. This may suggest need for long-term and persistent follow-up and rehabilitation procedures for populations exposed to this agent.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.9
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• pp.308-313
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• 2016

Modern systems have become more and more complex due to the ever-increasing user requirements and rapid advance of technology. As such, the frequency of accidents due to system design errors or failure has been increasing. When the damage incurred by accidents to human beings or property is serious, the underlying systems are referred to as safety-critical systems. The development of such systems requires special efforts to ensure the safety of the human beings operating them. To cope with such a requirement, in this paper an approach is employed in which we consider safety starting from the conceptual design phase of the systems. Specifically, a systems design method that can detect functional failure is proposed by utilizing meta-models and M&S methods. To accomplish this, the safety design data from international safety standards are first extracted and also a meta-model is generated using SysML (systems modeling language). Then, a SysML-based system design method is proposed based on the use of the developed meta-model. We also discuss how the safety requirements can be created and verified using a simulation method. Finally, through a case study in automotive design, it is demonstrated that the detection of a functional failure and the verification of a safety requirement can be accomplished using the SysML-based M&S method. This study indicates that the use of meta-models can be useful for collecting and managing safety data and that the meta-model based M&S method can make it possible to satisfy the system requirements by reducing the design errors.

• Journal of the Korean Institute of Landscape Architecture
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• v.28 no.1
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• pp.62-69
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• 2000

The purpose of this study is to evaluate naturalness of botanical garden pre- and post-assessed according to the Hemeroby Index in the case study of Daegok Botanical Garden. The results of the study are as follows. 1) The results of the site analysis according to the Hemeroby Index before development have been appeared that highest of poly/meta-hemeroby is 45.8% and the next of meso-hemeroby is 28.3%. 2) After development, the highest of meso-hemeroby is 53.6% and the next of $\alpha$ -euhemeroby is 28.3%. Generally, it is considered that the naturalness according to Hemeroby Indx was lasted higher after development than that before development. 3) Both a-hemeroby and oligo-hemeroby are not appeared before and after development. $\alpha$ -euhemeroby and meta-hemeroby are not appeared before development, but htey increased as much as 16.8% and 6.8% after development. Most of all, the increase of meta-hemeroby after development results from the increase of the artificial facilities (e.g. pavements, buildings and so on). 4) Specially, through the modification of play ground, park lot, pavement classified to meta-hemeroby, it is considered that the Hemeroby Index would be improved. 5) Compared with existing naturalness grade of green space, it has merits to apply Hemeroby Index, especially as a menas of distinguised naturalness assessment in various land use pattern. But there is no clear evidence that limits the minimum size that could be applied with Hemeroby Index. So, we must discuss whether it was useful to apply this standard to such a small specific space as the site of this study.

• The Journal of Korean Association of Computer Education
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• v.18 no.1
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• pp.21-33
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• 2015

The purpose of this study has been found to be effective using web-based instruction than traditional teaching-learning method on academic achievement applying the meta-analysis method. The results of this study were as follows: First, The 85% subject of analysis of web-based instruction selected in this study turned out to be clear effective than traditional teaching-learning method in academic achievement of students. Second, Web-based instruction is more effective for academic achievement of elementary school students and university students than for middle school students and high school students relatively. Third, Web-based instruction is a most effective method in social subject and physical education but less effective in language subject. The overall results of this study concluded more powerful and big decisions which have integrated each different effects on academic achievement of studies web-based instruction method applying meta-analysis. Through this study, make better results were obtained and suggested the base line data and direction for follow up studies.

• Physical Therapy Korea
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• v.19 no.2
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• pp.48-58
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• 2012

The objective of this study was to evaluate the effects of mirror therapy on motor function recovery following a stroke through a systemic review and meta-analysis. In total, nine of the 48 studies were identified from search engines between 1997 and 2011, as well as from a review of the reference lists of each identified study. The quality of each study was assessed using Jadad scale, and the effect size was calculated as a Cohen's effect size using MetaAnalyst (Beta 3.13). The overall effect size of the mirror therapy was 2.005 (95% confidence interval=1.041~2.970) in a random-effects model. This finding suggests that mirror therapy is beneficial for improving motor function following a stroke. The results from the subgroup analysis according to categorical variables were as follows: First, the effect size was larger for an onset time of less than 1 year (1.166) than for a duration of 1 year or more (.668). Second, the effect size of unpublished dissertations (1.610) was larger than published articles (1.221). Third, motor recovery of upper extremities (1.609) had a greater effect than motor recovery of lower extremities (.903). The major limitation of this study is the relatively small study population. Therefore, further individual studies of mirror therapy should be conducted in order to generalize the effects. In addition, mirror therapy supervised by a physical therapist should be recognized as a potential approach to manage motor function following a stroke and recommended to patients to improve their motor function.

• 전자공학회논문지 IE
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• v.47 no.2
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• pp.73-81
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• 2010

The main purpose of this study was to examine the effects of meta-cognition, learning flow and problem solving ability of the college engineering students on academic achievement. For this purpose, a total of 396 college engineering freshmen of the six different departments was chosen to conduct a survey. A hypothetical model was proposed, which was composed of meta-cognition, problem solving ability and learning flow as the prediction variables, and academic achievement as the outcome variables. The results of this study through multiple regression analysis showed that meta-cognition, learning flow and problem solving ability significantly influenced on the college engineering studnets' academic achievement. In addition, learning flow was used as a significant mediated variable in the relationships among meta-cognition, problem solving ability and academic achievement. Based on these study results, the above variables investigated in this study should be considered in the design and development of the college engineering courses that enable students to facilitate their problem-solving attitude and improve academic achievement.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.11a
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• pp.333-336
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• 2008

As the high-rise building increase due to the gravitation of population to big cities recently, it requires high quality and high performance of Concrete. As a result, people are keenly interested in Meta-kaolin as new admixture favorable from an economic perspective, which has strength and endurance with admixture at the same level like Silicafume. Accordingly, as to Meta-kaolin, this study was to set by three levels like domestic one, foreign one, and Silicafume, the waterbinding material ratio 25%, and four level substitute like 0, 10, 20, and 30(%) in order to compare and analyze the quality characteristics of high-strength concrete according to the substitute of Meta-kaolin applicable with replacement of Silicafume. As a result of performing experiment, as to the higher the additive amount of Superplasticizing agents in order to secure target liquidity was, the more the substitute in each admixture increased. This study had a tendency that the Silicafume increased the additive amount of Superplasticizing agents with high fineness compared with Meta-kaolin. In addition, the higher the substitute in each admixture was, the more its strength increased On the strength property, the higher the substitute in each admixture was, the more its strength increased. This study has found out that the Meta-kaolin has shown the better strength than the one of Silicafume. On the other hand, the relationship between the Compressive strength and Elastic coefficient has shown the similar formula suggested from ACI363.

• Korean Journal of Social Welfare Studies
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• v.49 no.3
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• pp.247-275
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• 2018

In the absence of a research study on meta-analysis in terms of program development, the purpose of the study is to analyze the contents of the meta-analysis research studies which has been conducted for 18 years, and is to identify the level of program component evidence for the development of social work program. In order to achieve these purposes, the study analyzed the feature and usefulness of the 110 meta-analysis studies(5,781 program evaluation studies)published from 2010 to June 2017 in major academic journals related to the areas of the social welfare, psychology, counseling and health. The major findings are as follows. The 110 meta-analysis studies tended to narrow down the scope of the population, problems, and program types, but they also included a lot of heterogeneous types. In the statistical methods, there were relatively few studies to explain the factors behind the heterogeneity of program effectiveness. In addition, researchers tended to select program components arbitrarily with bias on specific components. The important program components with the statistical validity are as follows; the age of the subjects, the severity of the problem, the expertise of the providers, and the strength and activities of the intervention, The academic meanings of the study results was discussed, and the direction of future research was presented to increase the usefulness of the metaanalysis for program development.