Kwon, Oran;Lee, Sunho;Ban, Soonhyun;Im, Jooyeon J.;Lee, Doo Suk;Lee, Eun Hee;Kim, Joohee;Lim, Soo Mee;Lee, Sang Gon;Kang, Ilhyang;Kim, Kyung-Hee;Yoon, Sujung;Lee, Sun Hea
Korean Journal of Biological Psychiatry
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v.22
no.2
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pp.63-77
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2015
Objectives The combination extract of four kinds of herbs, Gastrodia elata, Liriope platyphylla, Dimocarpus longan, and Salvia miltiorrhiza, has shown to have memory improving effects in mice. The aim of this study was to investigate the efficacy and safety of the herbal mixture for improving working memory as well as microstructural changes in white matter integrity in individuals with subjective memory complaints. Methods Seventy-five individuals with subjective memory complaints were assigned to receive either placebo (n = 15) or herbal mixture (low-dose group, n = 30 and high-dose group, n = 30) supplementation in an 8-week, randomized, double-blind, placebo-controlled clinical trial. Changes in working memory performance and fractional anisotropy (FA) values reflecting white matter integrity from baseline to 8-week endpoint were assessed. Results The herbal mixture group showed an increase in working memory performance compared to the placebo group (p for interaction = 0.001). In addition, the herbal mixture group showed an increase in FA values in the temporo-parietal regions (corrected p < 0.05), which are crucially involved in working memory function and are among the most affected regions in patients with cognitive impairments. Conclusions Findings from this study indicate that the herbal mixture may be a promising therapeutic option for individuals with subjective memory complaints.
Journal of The Korean Society of Integrative Medicine
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v.12
no.2
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pp.111-119
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2024
Purpose : This study aimed to demonstrate the effects of visiting cognitive activities using brain training on cognition, subjective memory complaints and depression among elderly participants residing in community living in Gwangmyeong city. Methods : Over a 14-month period (October 2022 to December 2023), four brain training instructors visited the homes of older adults and conducted the intervention using a brain training kit. The participants included 32 elderly individuals aged 65 years and older, who were living in Gwangmyeong city. The assessments were conducted by an occupational therapist, a nurse and a social worker at the Gwangmyeong dementia relief center. These assessments included the following the subjective memory complaints questionnaire (SMCQ), short geriatric depression scale-Korean (SGDS-K), a cognitive impairment screening test (CIST), the consortium to establish a registry for Alzheimer's disease-Korean (CERAD-K). The participants were divided into three groups (A: 20-30 points, B: 10-19 points, C: 1-9 points) based on the CIST score. For data analysis, descriptive statistics and wilcoxon signed-rank test were performed using SPSS 24.0, and the statistical level was at a=.05. Results : The results of the intervention showed that the SMCQ score of group A improved significantly (p<.05), the CIST score of group B also improved significantly (p<.05). However, the SGDS-K score of group C improved, but did not demonstrate statistical significance (p=.080). Conclusion : The visiting cognitive activities using brain training produced significant effects on cognition, depression, and subjective memory disorders, depending on the cognitive level of the elderly participants. In the future, it will be necessary to demonstrate the effects according to cognitive level in various aspects with more elderly people.
Journal of agricultural medicine and community health
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v.47
no.4
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pp.242-254
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2022
Purpose: This study was designed to test structural equation modeling of the quality of life of elderly diagnosed dementia living in the community in order to provide guidelines for development of intervention and strategies to improve their quality of life. Methods: The participants in the study were elderly who visited the public health center in C rural between May 30 and september 15, 2017. Data collection was carried out through one-on-one interviews. Demographic factors, knowledge, Attitude, Self-Efficacy, social support, accessibility, request for Information, health practice, depression, subjective memory complaints, dependence scale and quality of life were investigated. Results: The final analysis included 192 elderly. Fitness of the hypothesis model was appropriate(χ2=192.89, p=.000, GFI=0.90, SRMR=0.08, NNFI=0.94, CFI=0.95, PNFI=0.72, RMSEA=0.07). Depression, subjective memory complaints and dependence were found to be significant explaining varience in quality of life. Social support, dementia preventive behavior and health practice had an indirect effect on the quality of life. Conclusions: To improve the quality of life of elderly diagnosed dementia living in the community, comprehensive interventions are necessary to manage knowledge, attitude, self-efficacy, social support, health practice, depression, subjective memory complaints and dependence that can contribute to enchance the quality of life of elderly diagnosed dementia living in the community.
Objectives: This study aimed to investigate whether there was a connection between oral health and memory loss in elderly individuals with no abnormalities in their daily lives and to identify factors affecting memory loss. Methods: This study aimed to identify an association between the Geriatric Oral Health Assessment Index and Subjective Memory Complaints for the elderly individuals living in the community. Results: The results of analyzing the oral health assessment according to the general characteristics of the study participants revealed that with increase in age, income (p=0.05) and oral health of the elderly living alone decreased compared to those living together in the family (p=0.05). Moreover, the lower the income (p=0.05), the higher was the memory loss for the elderly living alone than for the elderly living together with their family (p=0.05). Conclusions: The study identified a link between oral health of the elderly and subjective memory loss and observed that oral health, cohabitation, and income level were related to subjective memory loss. Therefore, oral health should be considered as a predictor of memory loss for the elderly.
Purpose: The purpose of this study was to design a mobile-application of a cognitive training program for people who have chemo-related cognitive complaints. Methods: The program was developed based on the network-based instructional system design proposed by Jung. The program consisted of several tasks centered on four cognitive domains: learning, memory, working memory, and attention. For memory learning, a target-image and all its elements (color, position, and number) were presented on the screen that had to be recognized among a number of distractor-figures. In working memory training, the previous learned target-figure according to the level of difficulty had to be remembered among many different figures. In attention training named "Find the same figure," two identical symbols in a grid-pattern filled with different images were presented on the screen, and these had to be simultaneously touched. In attention training named "Find the different figure," a different symbol in a grid pattern filled with same figures had to be selected. This program was developed to train for a minimum of 20 min/day, four days/week for six weeks. Results: This cognitive training revealed statistically significant improvement in subjective cognitive impairments (t=3.88, p=.006) at six weeks in eight cancer survivors. Conclusion: This cognitive training program is expected to offer individualized training opportunities for improving cognitive function and further research is needed to test the effect in various settings.
Objectives It was the aim to examine the association of the thyroid-related hormones with cognitive function, depression, and subjective memory impairment in community-dwelling elders with questionable dementia. Methods The sample consisted of 399 community residents with 'questionable dementia' aged 60 or over in whom serum thyroid-related hormones [thyroid stimulating hormone (TSH) and thyroxine] had been assayed. Cognitive impairment was defined using the Korean version of the Consortium Establish a Registry for Alzheimer's Disease. Depression was diagnosed using the Korean version of Geriatric Depression Scale and subjective memory complaint (SMC) was checked using the subjective memory complaints questionnaire (SMCQ). Age, gender, education, and the presence of apolipoprotein E {\varepsilon}4 were included as covariates. Results There was a significant positive association between verbal fluency test (VFT) score and serum TSH levels (p = 0.01). There was a significant negative association between SMCQ total score and word list memory test (WLMT)(p = 0.002) or word list recall test (WLRT) score (p = 0.013). Conclusions Lower serum TSH levels were associated with semantic memory (VFT), and we found that SMC was associated with episodic memory (WLMT and WLRT) in this sample.
This paper is concerned with the effectiveness of songs in the acquisition of formulaic sequences in the college EFL classroom. The existing research mentions the use of songs in terms of the power of their melodies (Fonseca-Mora, 2000), linguistic features in song lyrics (Abbott, 2002), and the emotional basis of memory (LI & Brand, 2009). Learners' opinions about the use of songs has been ignored, however. In this paper, seven subjects with English ability ranging from advanced (one) intermediate-high (three), intermediate-middle (two), and intermediate-low (one) studied five different pop songs. The results showed that they did not agree with the existing research findings. Rather, they were negative about using songs in the classroom. Their complaints were the burden of using too many hours to memorize lyrics, few language expressions to learn, and too much emphasis on expressions about love and feelings. Students at all levels expressed similar negativity about the use of songs. When their complaints were discussed during interviews, however, their attitude changed from negative to positive. The case study in this paper was on a small-scale but it is suggested that through further research the use of songs could be activated in the EFL classroom. Considering college language learners disregard most existing EFL materials, it appears to be worthwhile to continue further with this kind of research.
This study was a quasi-experimental study to confirm the effects of a memory training program using efficacy sources. The purpose was to develop an effective memory training program for elderly people and to identify the effects of the memory training program. This study was carried out between February 24 and July 18, 1999 and the subjects of the study were 102 elderly people who were participants at a welfare institute in Seoul. The experimental group (51) and the control group (51) were assigned by means of participation order. The control group was matched to the experimental group and was selected considering age, sex, and religion. The experimental group participated in the memory training program. The memory training program was based on the literature of Fogler & Stern (1994), Wang & Lee (1990), Lee (1991) and Lee (1993). The memory training program was given twice a week for two weeks with each program lasting two hours. Task centered memory self-efficacy was measured using the Memory Self-Efficacy Scale developed by Berry & Dennehey (1989) and Meta Memory was measured by the MIA developed by Dixon et al. (1988) Memory performance was measured by the word list developed by Cho Sung Won (1995) and the face recognition task (Face Recognition Task developed for this study). Data were analyzed by SPSS PC and the results are described below. 1. The experimental group which participated in the Memory Training Program showed higher task centered memory self-efficacy scores as compared to the control group (t=4.354, P=.0001). 2. The experimental group which participated in the Memory Training Program showed higher metamemory scores as compared to the control group (t=4.733, P=.0001). 3. The experimental group which participated in the Memory Training Program showed higher memory performance scores as compared to the control group (t=7.500, P=.0001). The memory performance involved an immediate word recall task, a delayed word recall task, a word recognition task, and the face recognition task. 4. In the experimental group, there was significant correlation between the task centered memory self-efficacy scores and the metamemory scores (r=.382, P=.006), but the correlation between the task centered memory self-efficacy scores and the memory performance scores and between the metamemory scores and the memory performance scores were not significant. The results showed that task centered memory self-efficacy, meta memory and memory performance improved following the Memory Training Program including the memory process, changes in memory with aging, and appropriate use of memory strategies. Memory Training Program is an effective nursing intervention for improving memory in elderly people and, also, in people with complaints of memory loss.
Crime amount prediction is crucial for optimizing the police patrols' arrangement in each region of a city. First, we analyzed spatiotemporal correlations of the crime data and the relationships between crime and related auxiliary data, including points-of-interest (POI), public service complaints, and demographics. Then, we proposed a crime amount prediction model based on 2D convolution and long short-term memory neural network (2DCONV-LSTM). The proposed model captures the spatiotemporal correlations in the crime data, and the crime-related auxiliary data are used to enhance the regional spatial features. Extensive experiments on real-world datasets are conducted. Results demonstrated that capturing both temporal and spatial correlations in crime data and using auxiliary data to extract regional spatial features improve the prediction performance. In the best case scenario, the proposed model reduces the prediction error by at least 17.8% and 8.2% compared with support vector regression (SVR) and LSTM, respectively. Moreover, excessive auxiliary data reduce model performance because of the presence of redundant information.
Journal of the Korea Academia-Industrial cooperation Society
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v.16
no.11
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pp.7414-7423
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2015
Subjective cognitive-linguistic complaints in older adults contribute to the diagnostic and prognostic investigation of MCI or dementia. However, the utility of subjective test for predicting cognitive-linguistic decline is controversial. Few domestic studies have included the correlation between subjective and objective tests systematically. The current study analyzed 26 studies published since 2000, and the effect sizes of their correlation coefficients between two tests were computed. The results of qualitative analysis indicated that the number of subjects ranged from 26 to 657. Subjective tests included the self-report 75.4% and the informant-report 24.6%. In objective tests, memory comprised the largest proportion, followed by global cognition, and language, etc. As a result of meta-analysis, self-report test had the predictive value for dementia, and informant-report test contributed to discriminate among 3 groups. In the elderly group, self-report test was correlated with reasoning, and informant-report test with memory and language. In MCIs, self-report test predicted several abilities including language, and informant-report test signaled the future decline of domains like global cognition. Two types of subjective tests in dementia also represented memory, language, and global cognition accurately. This study provides evidence-based information to support relationships between subjective and objective tests for cognitive-linguistic ability in 3 groups.
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