• Title/Summary/Keyword: Membrane interaction

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Effects of Polymer Material and Solvent Properties on the Performance of Organic Solvent Nanofiltration Membranes (고분자 소재와 용매특성에 따른 유기용매 나노여과막 성능 분석)

  • Choi, JiHyun;Kim, Jeong F.
    • Membrane Journal
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    • v.32 no.1
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    • pp.50-56
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    • 2022
  • In this work, the solvent permeation and separation performance of organic solvent nanofiltration (OSN) membranes were evaluated. Particularly, the PuraMem (PM) series developed for nonpolar solvents were analyzed and tested in dead-end filtration system. PM membranes exhibited higher permeance for nonpolar solvents compared to polar solvents, and their rejection data did not follow conventional trends with respect to solute size. The data showed that simple solution-diffusion model is not suitable to describe the OSN membrane behavior, and a better solvent-solute-membrane interaction parameter must be developed.

Specific Interaction of Rat Vanilloid Receptor, TRPV1 with Rab11-FIP3 (Rat 바닐로이드 수용체 TRPV1과 Rab11-FIP3의 특이적 결합)

  • Lee, Soon-Youl;Kim, Mi-Ran
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.1
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    • pp.312-317
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    • 2011
  • Vanilloid receptor TRPV1 (known as capsaicin channel, transient receptor potential vanilloid 1) is known to be a key protein in the pain signal transduction. However, the proteins controlling the activity of the channel are not much known yet. Recently mouse Rab11-FIP3 (Rab11-family interaction protein 3) was found and reported to interact with rat TRPV1. Rab11 has been shown to play a key role in a variety of cellular processes including plasma membrane recycling, phagocytosis, and transport of secretory proteins from the trans-Golgi network. Therefore, Rab11-FIP3 was proposed to be involved in the membrane trafficking of TRPV1. In this study, the unreported rat Rab11-FIP3 was yet cloned in order to show the specific interaction of the TRPV1 and Rab11-FIP3 in the same species of rat and to examine the membrane trafficking of TRPV1. The result showed that rat Rab11-FIP3 is expected to have 489 amino acids and showed 80% identity with that of human and over 90% identity with that of mouse. Rab11-FIP3 was found to be expressed in heart, brain, kidney, testis using northern and western blot analyses. We also found that rat Rab11-FIP3 was colocalized with rat TRPV1 but not with TRPV2 of same family in the rat brain by using immunohistochemistry showing that two proteins interact specifically, suggesting the role of Rab11-FIP3 in the membrane trafficking.

Flow/solid Interaction Analysis for Design of Medical CSF-Flow Control Valve (의료용 CSF 제어 밸브 설계를 위한 유동/구조 상호작용 해석)

  • Won C. S.;Hur N.;Lee C .S.
    • 한국전산유체공학회:학술대회논문집
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    • 2000.05a
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    • pp.21-26
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    • 2000
  • Pressure-flow control characteristics of a commercially available cerebrospinal flow(CSF) control shunt valve was tested using fluid-solid interaction analysis. Pre-stress of the valve diaphragm(membrane) was computed for proper valve opening. The results were ir good agreements with the valve specification listed in the commercially available CSF control valve. The results of the study can be effectively used to design variety of CSF control shunt valves.

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Effect of Electrode Degradation on the Membrane Degradation in PEMFC (PEMFC에서 전극 열화가 전해질 막 열화에 미치는 영향)

  • Song, Jinhoon;Kim, Saehoon;Ahn, Byungki;Ko, Jaijoon;Park, Kwonpil
    • Korean Chemical Engineering Research
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    • v.51 no.1
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    • pp.68-72
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    • 2013
  • Until a recent day, degradation of PEMFC MEA (membrane and electrode assembly) has been studied, separated with membrane degradation and electrode degradation, respectively. But membrane and electrode were degraded coincidentally at real PEMFC operation condition. During simultaneous degradation, there was interaction between membrane degradation and electrode degradation. The effect of electrode degradation on membrane degradation was studied in this work. We compared membrane degradation after electrode degradation and membrane degradation without electrode degradation. I-V performance, hydrogen crossover current, fluoride emission rate (FER), impedance and TEM were measured after and before degradation of MEA. Electrode degradation reduced active area of Pt catalyst, and then radical/$H_2O_2$ evolution rate decreased on Pt. Decrease of radical/$H_2O_2$ reduced the velocity of membrane degradation.

Effect of Membrane Degradation on the Electrode Degradation in PEMFC (PEMFC에서 막 열화가 전극 열화에 미치는 영향)

  • Song, Jinhoon;Jeong, Jaejin;Jeong, Jaehyeun;Kim, Saehoon;Ahn, Byungki;Ko, Jaijoon;Park, Kwonpil
    • Korean Chemical Engineering Research
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    • v.51 no.3
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    • pp.325-329
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    • 2013
  • The membrane and electrode were degraded coincidentally at real PEMFC(Proton Exchange Membrane Fuel Cells) operation condition. But the interaction membrane degradation between electrode degradation has not been studied. The effect of membrane degradation on electrode degradation was studied in this work. We compared electrode degradation after membrane degradation and electrode degradation without membrane degradation. I-V performance, hydrogen crossover current, impedance and TEM were measured after and before degradation of MEA. Membrane degradation enhanced hydrogen crossover, and then Pt particle growth rate was reduced. Increase of hydrogen crossover by membrane degradation reduced the electrode degradation rate.

Study on Hindered Diffusion of Single Polyelectrolyte Chain in Micro-Pores by Employing Brownian Dynamics Simulations (브라운 동력학 시뮬레이션에 의한 미세기공에서 단일한 다가전해질 사슬의 제한확산 연구)

  • 전명석;곽현욱
    • Membrane Journal
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    • v.12 no.4
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    • pp.207-215
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    • 2002
  • The hindered diffusion in confined spaces is an important phenomenon to understand in a micro-scale the filtration mechanism determined by the particle motion in membrane pores. Compared to the case of spherical colloids, both the theoretical investigations and the experiments on the hindered diffusion of polyelectrolytes is actually more difficult, due to lots of relevant parameters resulting from the complicated conformational properties of the polyelectrolyte chain. We have successfully performed the Brownian dynamics simulations upon a single polyeiectrolyte confined in a slit-like pore, where a coarse-grained bead-spring model incorporated with Debye-Huckel interaction is properly adopted. For the given sizes of both the polyelectrolyte and the pore width, the hindered diffusion coefficient decreases as the solution ionic concentration decreases. It is evident that a charge effect of the pore wall enhances the hindered diffusion of polyelectrolyte. Simulation results allow us to make sense of the diffusive transport through the micro-pore, which is restricted by the influences of the steric hindrance of polyelectrolytes as well as the electrostatic repulsion between the polyelectrolytes and pore wall.

Counterion Specific Conformational Transition and ion Selective Transport of a Poly(L-glutamic acid)/PVA Blend Membrane (Poly(L-glutamic acid)/PVA 블렌드막의 대이온 선택적인 구조전이와 이온투과 특성)

  • 허양일
    • Polymer(Korea)
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    • v.24 no.6
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    • pp.802-809
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    • 2000
  • Counterion-specific helix formation and ion-selective transport of alkali metal chlorides (LiCl, NaCl, KCl, CsCl) were investigated for a poly(L-glutamic acid)(PLGA)/poly (vinyl alcohol)(PVA) blend membrane immersed in aqueous ethanol. The counterion specificity for helix formation of PLG alkali metal salts in the membrane was Li>Na>K>Cs. This specificity is ascribed to a contact ion-pair formation between the PLG carboxyl anion and the bound counterion, which depends on the energy balance between the electrostatic interaction and the desolvation. In aqueous ethanol, an appreciable ion-selectivity was observed for the permeability coefficient, i.e. Li$^{+}{\cdot}$Cl$^{-}$) formation between counterion and coion, and the latter to a specific interaction of diffusing counterions with polymer charges.

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The selection of basic platform for improving the sensitivity of neutravidin rapid detection kit (뉴트라비딘 검출용 간이 진단키트의 성능향상을 위한 기본 플랫폼 선정)

  • Choi, Sunmi;Kim, Giyoung;Om, Aeson;Moon, Jihea;Park, Saetbyeol;Lee, Sangdae;Kim, Hyuk Joo
    • Korean Journal of Agricultural Science
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    • v.39 no.4
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    • pp.613-618
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    • 2012
  • This study was performed to optimize the basic platform of a lateral flow immunoassay. Improvement of the limit of detection (LOD) was evaluated according to the width of a nitrocellulose membrane with varying concentrations of analyte. The analyte, neutravidin was detected based on the avidin-biotin interaction. The antibody-Au nanoparticle conjugation was mostly stabled in a PBS buffer of pH 7.3. The optimal widths of a nitrocellulose membrane were 4 and 6 mm considering the sample flow rate and signal strength of the test line on the membrane. The LOD of neutravidin was 0.001 mg/ml in the optimum conditions.

Wet Drop Impact Response Analysis of CCS in Membrane Type LNG Carriers -I : Development of Numerical Simulation Analysis Technique through Validation- (멤브레인형 LNG선 화물창 단열시스템의 수면낙하 내충격 응답해석 -I : 검증을 통한 수치해석 기법 개발-)

  • Lee, Sang-Gab;Hwang, Jeong-Oh;Kim, Wha-Soo
    • Journal of the Society of Naval Architects of Korea
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    • v.45 no.6
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    • pp.726-734
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    • 2008
  • While the structural safety assessment of Cargo Containment System(CCS) in membrane type LNG carriers has to be carried out in consideration of sloshing impact pressure, it is very difficult to figure out its dynamic response behaviors due to its very complex structural arrangements/materials and complicated phenomena of sloshing impact loading. For the development of its original technique, it is necessary to understand the characteristics of dynamic response behavior of CCS structure under sloshing impact pressure. In this study, for the exact understanding of dynamic response behavior of CCS structure in membrane Mark III type LNG carriers under sloshing impact pressure, its wet drop impact response analyses were carried out by using Fluid-Structure Interaction(FSI) analysis technique of LS-DYNA code, and were also validated through a series of wet drop experiments for the enhancement of more accurate shock response analysis technique. It might be thought that the structural response behaviors of impact response analysis, such as impact pressure impulses and resulted strain time histories, generally showed very good agreement with experimental ones with very appropriate use of FSI analysis technique of LS-DYNA code, finite element modeling and material properties of CCS structure, finite element modeling and equation of state(EOS) of fluid domain.

Wet Drop Impact Response Analysis of CCS in Membrane Type LNG Carriers -II : Consideration of Effects on Impact Response Behaviors- (멤브레인형 LNG선 화물창 단열시스템의 수면낙하 내충격 응답해석 -II : 내충격 응답거동에 미치는 영향 고찰-)

  • Lee, Sang-Gab;Hwang, Jeong-Oh;Kim, Wha-Soo
    • Journal of the Society of Naval Architects of Korea
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    • v.45 no.6
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    • pp.735-749
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    • 2008
  • For the development of the original technique of structural safety assessment of Cargo Containment System(CCS) in membrane type LNG carriers, it is necessary to understand the characteristics of dynamic response behavior of CCS structure under sloshing impact pressure. In the previous study, the wet drop impact response analyses of CCS structure in membrane Mark III type LNG carriers were carried out by using Fluid-Structure Interaction(FSI) analysis technique of LS-DYNA code, and were also validated through a series of wet drop experiments for the enhancement of more accurate shock response analysis technique. In this study, the characteristics of structural shock response behaviors of CCS structure were sufficiently figured out by careful examinations of the effects of specimen weight, drop height, incident angle, corrugation and stiffness of inner hull on its shock response behaviors. The shock response analysis of upward shooting fluid to inner hull was performed, and the reason of faster strain response than shock pressure one was also figured out.