• Journal of Korean Society of Environmental Engineers
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• v.37 no.11
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• pp.607-618
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• 2015

This study was conducted to suggest hydraulic modification for improving evenness of inlet flow distribution into side stream type low-pressure MF (microfiltration) module using CFD (computational fluid dynamics) simulation and PIV (particle image velocimetry) techniques. From the results of CFD simulation for various typed inlet structure, it was investigated that installing internal orifice baffle in inlet the distribution channel could improve the evenness of inlet flow distribution over about 40%. Also, from the results of PIV measurements which were carried out for verifying the CFD simulation, it was observed that the momentum of the water body coming from the opposite side of the inlet was relatively larger. This momentum would generate strong shear force in the near of inlet side wall. On the other hands, occurrence of dead zone and eddy flow was confirmed in the opposite side.

• Journal of the Korean Society of Hazard Mitigation
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• v.7 no.5
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• pp.47-60
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• 2007

In this paper, we investigate the natural frequencies and buckling loads of functionally graded material (FGM) plates and shells, using a quasi-conforming shell element that accounts for the transverse shear strains and rotary inertia. The eigenvalue of the FGM plates and shells are calculated by varying the volume fraction of the ceramic and metallic constituents using a sigmoid function, but their Poisson's ratios of the FGM plates and shells are assumed to be constant. The expressions of the membrane, bending and shear stiffness of FGM shell element are more complicated combination of material properties than a homogeneous element. In order to validate the finite element numerical solutions, the Navier's solutions of rectangular plates based on the first-order shear deformation theory are presented. The present numerical solutions of composite and sigmoid FGM (S-FGM) plates are proved by the Navier's solutionsand various examples of composite and FGM structures are presented. The present results are in good agreement with the Navier's theoretical solutions.

• Korean Chemical Engineering Research
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• v.54 no.6
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• pp.847-853
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• 2016

Here has been examined a 3-dimensional computational fluid dynamics (CFD) modeling in order to investigate the performance analysis of proton exchange membrane (PEM) fuel cells with serpentine flow fields. The present CFD model considers the isothermal transport phenomena in a fuel cell involving mass, momentum transport, electrode kinetics, and potential fields. Co-current flow patterns for a PEMFC are considered for various geometries in the single straight cell. Current density distribution from the calculated distribution of oxygen and hydrogen mass fractions has been determined, where the activation overpotential has been also calculated within anode and cathode. CFD results showed that profiles differ from those simulations subjected to each the calculated activation overpotential. It is interesting that the present serpentine flow field shows the specific distribution of current density with respect to the aspect ratio of depth to width and the ratio of reaction area for various serpentine geometries. Simulation results were considered reasonable with the other CFD results reported in literature and global comparisons of the PEMFC model.

• Korean Journal of Ecology and Environment
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• v.49 no.2
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• pp.67-79
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• 2016

Cyanotoxins in aquatic ecosystems have been investigated by many researchers worldwide. Cyanotoxins can be classified according to toxicity as neurotoxins (anatoxin-a, anatoxin-a(s), saxitoxins) or hepatotoxins (microcystins, nodularin, cylindrospermopsin). Microcystins are generally present within cyanobacterial cells and are released by damage to the cell membrane. Cyanotoxins have been reported to cause adverse effects and to accumulate in aquatic organisms in lakes, rivers and oceans. Possible pathways of microcystins in Lake Suwa, Japan, have been investigated from five perspectives: production, adsorption, physiochemical decomposition, bioaccumulation and biodegradation. In this study, temporal variability in microcystins in Lake Suwa were investigated over 25 years (1991~2015). In nature, microcystins are removed by biodegradation of microorganisms and/or feeding of predators. However, during water treatment, the use of copper sulfate to remove algal cells causes extraction of a mess of microcystins. Cyanotoxins are removed by physical, chemical and biological methods, and the reduction of nutrients inflow is a basic method to prevent cyanobacterial bloom formation. However, this method is not effective for eutrophic lakes because nutrients are already present. The presence of a cyanotoxins can be a potential threat and therefore must be considered during water treatment. A complete understanding of the mechanism of cyanotoxins degradation in the ecosystem requires more intensive study, including a quantitative enumeration of cyanotoxin degrading microbes. This should be done in conjunction with an investigation of the microbial ecological mechanism of cyanobacteria degradation.

• Molecules and Cells
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• v.43 no.9
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• pp.821-830
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• 2020

Altered dendritic morphology is frequently observed in various neurological disorders including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), but the cellular and molecular basis underlying these pathogenic dendritic abnormalities remains largely unclear. In this study, we investigated dendritic morphological defects caused by dipeptide repeat protein (DPR) toxicity associated with G4C2 expansion mutation of C9orf72 (the leading genetic cause of ALS and FTD) in Drosophila neurons and characterized the underlying pathogenic mechanisms. Among the five DPRs produced by repeat-associated non-ATG translation of G4C2 repeats, we found that arginine-rich DPRs (PR and GR) led to the most significant reduction in dendritic branches and plasma membrane (PM) supply in Class IV dendritic arborization (C4 da) neurons. Furthermore, expression of PR and GR reduced the number of Golgi outposts (GOPs) in dendrites. In Drosophila brains, expression of PR, but not GR, led to a significant reduction in the mRNA level of CrebA, a transcription factor regulating the formation of GOPs. Overexpressing CrebA in PR-expressing C4 da neurons mitigated PM supply defects and restored the number of GOPs, but the number of dendritic branches remained unchanged, suggesting that other molecules besides CrebA may be involved in dendritic branching. Taken together, our results provide valuable insight into the understanding of dendritic pathology associated with C9-ALS/FTD.

• Nuclear Engineering and Technology
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• v.56 no.3
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• pp.893-899
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• 2024

In a secondary cooling system of a sodium-cooled fast reactor (SFR), rapid detection of hydrogen due to sodium-water reaction (SWR) caused by water leakage from a heat exchanger tube of a steam generator (SG) is important in terms of safety and property protection of the SFR. For hydrogen detection, the hydrogen detectors using atomic transmission phenomenon of hydrogen within Ni-membrane were used in Japanese proto-type SFR "Monju". However, during the plant operation, detection signals of water leakage were observed even in the situation without SWR concerning temperature up and down in the cooling system. For this reason, the study of a new hydrogen detector has been carried out to improve stability, accuracy and reliability. In this research, the authors focus on the difference in composition of hydrogen and the difference between the background hydrogen under normal plant operation and the one generated by SWR and theoretically estimate the hydrogen behavior in liquid sodium by using ultra-accelerated quantum chemical molecular dynamics (UA-QCMD). Based on the estimation, dissolved H or NaH, rather than molecular hydrogen (H₂), is the predominant form of the background hydrogen in liquid sodium in terms of energetical stability. On the other hand, it was found that hydrogen molecules produced by the sodium-water reaction can exist stably as a form of a fine bubble concerning some confinement mechanism such as a NaH layer on their surface. At the same time, we observed experimentally that the fine H₂ bubbles exist stably in the liquid sodium, longer than previously expected. This paper describes the comparison between the theoretical estimation and experimental results based on hydrogen form in sodium in the development of the new hydrogen detector in Japan.

• The Korean Journal of Physiology and Pharmacology
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• v.16 no.4
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• pp.255-264
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• 2012

The structures of the intact synaptosomal plasma membrane vesicles (SPMVs) isolated from bovine cerebral cortexs, and the outer and the inner monolayer separately, were evaluated with 1,6-diphenyl-1,3,5-hexatriene (DPH) and 1,3-di(1-pyrenyl)propane (Py-3-Py) as fluorescent reporters and trinitrophenyl groups as quenching agents. The methanol increased bulk rotational and lateral mobilities of SPMVs lipid bilayers. The methanol increased the rotational and lateral mobilities of the outer monolayers more than of the inner monolayers. n-(9-Anthroyloxy)stearic acid (n-AS) were used to evaluate the effect of the methanol on the rotational mobility at the 16, 12, 9, 6, and 2 position of aliphatic chains present in phospholipids of the SPMVs outer monolayers. The methanol decreased the anisotropy of the 16-(9-anthroyloxy)palmitic acid (16-AP), 12-(9-anthroyloxy)stearic acid (12-AS), 9-(9-anthroyloxy)stearic acid (9-AS), and 6-(9-anthroyloxy)stearic acid (6-AS) in the SPMVs outer monolayer but it increased the anisotropy of 2-(9-anthroyloxy)stearic acid (2-AS) in the monolayers. The magnitude of the increased rotational mobility by the methanol was in the order at the position of 16, 12, 9, and 6 of aliphatic chains in phospholipids of the outer monolayers. Furthermore, the methanol increased annular lipid fluidity and also caused membrane proteins to cluster. The important finding is that was far greater increase by methanol in annular lipid fluidity than increase in lateral and rotational mobilities by the methanol. Methanol alters the stereo or dynamics of the proteins in the lipid bilayers by combining with lipids, especially with the annular lipids. In conclusion, the present data suggest that methanol, in additions to its direct interaction with proteins, concurrently interacts with membrane lipids, fluidizing the membrane, and thus inducing conformational changes of proteins known to be intimately associated with membranes lipids.

• Journal of the Korean Solar Energy Society
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• v.32 no.spc3
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• pp.289-294
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• 2012

In recent years, understanding the dynamics of DC distribution system has become critically important due mainly to the increasing needs for the interconnection of DC distributed generators and the (DC-based) electric vehicle (EV) charging systems. In this paper, the characteristics of the DC grid system connected to the compact proton exchange membrane fuel cell (PEMFC) has been studied. In particular, the voltage and current transient phenomena were measured by varying the load of the DC grid system. Also, the voltage and current ripple were measured at the different load conditions. Our experimental results clearly manifested that the study contributes to the establishment of fundamental method to characterize the small DC grid system including distributed generation.

• Journal of the Korean Society of Combustion
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• v.18 no.1
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• pp.21-26
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• 2013

In the Shell coal gasification process, the syngas produced in a gasifier passes through a syngas cooler for steam production and temperature control for gas cleaning. Fly slag present in the syngas may cause major operational problems such as erosion, slagging, and corrosion, especially in the upper part of the syngas cooler (gas reversal chamber, GRC). This study investigates the flow, heat transfer and particle behaviors in the GRC for a 300 MWe IGCC process using computational fluid dynamics. Three operational loads of 100%, 75% and 50% were considered. The gas and particle flows directly impinged on the wall opposite to the syngas inlet, which may lead to erosion of the membrane wall. The heat transfer to the wall was mainly by convection which was larger on the side wall at the inlet level due to the expansion of the cross-section. In the evaporator below the GRC, the particles were concentrated more on the outer channels, which needs to be considered for alleviation of fouling and blockage.

• The Transactions of the Korean Institute of Power Electronics
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• v.9 no.3
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• pp.222-230
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• 2004

In this paper, a 3㎾ fuel cell generation system with an active fuel cell simulator has been proposed. The developed fuel cell simulator generates the actual voltage and current output characteristics of the Polymer Electrolyte Membrane Fuel Cell (PEMFC), so that the overall performance and the dynamics of the proposed system could be effectively examined and tested. In This paper, at first, the system configuration and operational principle of the developed fuel cell simulator has been investigated and the design process of the fuel cell generation system is explained in detail. In addition, the validity of the proposed system has been verified lly the informative simulation and experimental result