• 제목/요약/키워드: Medical optics

검색결과 163건 처리시간 0.027초

Effects of Lepidii Semen on Acute Edematous Lung Injury Induced by Skin Burn

  • Myoung-Je Cho;Hyun Gug Cho
    • 대한의생명과학회지
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    • 제9권1호
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    • pp.37-42
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    • 2003
  • The present study was conducted to determine whether administration of heat extract of Lepidii Semen has an inhibitory effect on neutrophil-derived oxidative injury following dermal scald burn in rats. Acute lung injury was induced by scald burn (15% of TBSA) in rats. To identify acute edematous lung injury, protein concentrations and numbers of polymorphonuclear leukocytes were measured in bronchoalveolar lavage (BAL) at 5 h after skin burn. In addition, the level of lung KC (neutrophil chemoattractant cytokine) and activity of lung myeloperoxidase (MPO) were measured, and histopathological changes were observed as well. Lung weight and concentration of BAL protein, the index of lung injury, were clearly increased at 5 h postburn compared with those of sham-operated group. Administration of heat extract of Lepidii Semen after scald burn inhibited the production of KC in lung tissue and decreased the activity of lung MPO related to infiltration of neutrophils. In histopathological changes in lung tissue, infiltration of inflammatory cells and pulmonary edema induced by skin burn were decreased by administration of heat extract of Lepidii Semen after scald burn. These results suggest that Lepidii Semen may be an effective medical stuff for acute lung injury induced by skin burn.

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Ultrastructure of the Fertilized Egg Envelope from Pseudobagrus fulvidraco, Bagridae, Teleostei

  • Sohn, Joon Hyung;Kwon, Ohyun;Kim, Dong Heui
    • Applied Microscopy
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    • 제46권3호
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    • pp.150-154
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    • 2016
  • The ultrastructure of fertilized egg envelope from Pseudobagrus fulvidraco belongs to Bagridae was investigated using light and electron microscopes. The fertilized egg was compressed spherical, light-yellowish, demersal, and adhesive. The size of fertilized egg is about $1.85{\pm}0.13mm$, perivitelline space is not well developed, and there were no appendicular structures on the outer surface of egg envelope and oil droplets in vitelline membrane under light microscope. The micropyle was located in the animal pole of fertilized egg. Adhesive reticular fiber was covered fertilized egg envelope. The thickness of egg envelope was about $3.7{\sim}4.2{\mu}m$, and the egg envelope consisted of two layers: an outer, electron-dense adhesive fibers layer and an simple inner layer with pore. Therefore, the ultrastructure of cross section of the fertilized egg envelope showed species specificity, but studies on the other species belongs to Bagridae were need to get correct information about common traits in family.

All-fiber Tm-Ho Codoped Laser Operating at 1700 nm

  • Park, Jaedeok;Ryu, Siheon;Yeom, Dong-Il
    • Current Optics and Photonics
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    • 제2권4호
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    • pp.356-360
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    • 2018
  • We demonstrate continuous-wave operation of an all-fiber thulium-holmium codoped laser operating at a wavelength of 1706.3 nm. To realize laser operation in the short-wavelength region of the emission-band edge of thulium in silica fiber, we employ fiber Bragg gratings having resonant reflection at a wavelength around 1700 nm as a wavelength-selective mirror in an all-fiber cavity scheme. We first examine the performance of the laser by adjusting the central wavelength of the in-band pump source. Although a pump source possessing a longer wavelength is observed to provide reduced laser threshold power and increased slope efficiency, because of the characteristics of spectral response in the gain fiber, we find that the optimal pump wavelength is 1565 nm to obtain maximum laser output power for a given system. We further explore the properties of the laser by varying the fiber gain length from 1 m to 1.4 m, for the purpose of power scaling. It is revealed that the laser shows optimal performance in terms of output power and slope efficiency at a gain length of 1.3 m, where we obtain a maximum output power of 249 mW for an applied pump power of 2.1 W. A maximum slope efficiency is also estimated to be 23% under these conditions.

Avalanche and Bit Independence Properties of Photon-counting Double Random Phase Encoding in Gyrator Domain

  • Lee, Jieun;Sultana, Nishat;Yi, Faliu;Moon, Inkyu
    • Current Optics and Photonics
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    • 제2권4호
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    • pp.368-377
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    • 2018
  • In this paper, we evaluate cryptographic properties of a double random phase encoding (DRPE) scheme in the discrete Gyrator domain with avalanche and bit independence criterions. DRPE in the discrete Gyrator domain is reported to have higher security than traditional DRPE in the Fourier domain because the rotation angle involved in the Gyrator transform is viewed as additional secret keys. However, our numerical experimental results demonstrate that the DRPE in the discrete Gyrator domain has an excellent bit independence feature but does not possess a good avalanche effect property and hence needs to be improved to satisfy with acceptable avalanche effect that would be robust against statistical-based cryptanalysis. We compare our results with the avalanche and bit independence criterion (BIC) performances of the conventional DRPE scheme, and improve the avalanche effect of DRPE in the discrete Gyrator domain by integrating a photon counting imaging technique. Although the Gyrator transform-based image cryptosystem has been studied, to the best of our knowledge, this is the first report on a cryptographic evaluation of discrete Gyrator transform with avalanche and bit independence criterions.

Cerebral Blood Flow Monitoring by Diffuse Speckle Contrast Analysis during MCAO Surgery in the Rat

  • Yeo, Chaebeom;Kim, Heejaung;Song, Cheol
    • Current Optics and Photonics
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    • 제1권5호
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    • pp.433-439
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    • 2017
  • The rodent model has been used frequently to understand stroke pathophysiology, due to its low cost and the large spectrum of genetic strains available. Here, we present a diffuse speckle contrast analysis system (DSCA) with a $1{\times}2$ optical switch that was used to non-invasively assess cerebral blood flow (CBF) changes in the rat during intraluminal suturing for middle cerebral artery occlusion (MCAO) surgery. The blood flow index (BFI) in the left hemisphere was lower than that in the right hemisphere because the left middle cerebral artery was occluded. Furthermore, the performance of the DSCA system was compared with that of commercial laser Doppler flowmetry. The changes in the BFI measured by the two systems were correlated strongly. The DSCA system was less sensitive to motion artifacts and able to measure relatively deep tissue flow in the rat's brain. In conclusion, the DSCA system secured CBF monitoring during surgery in a rodent model without craniotomy.

An Optical Design of Off-axis Four-mirror-anastigmatic Telescope for Remote Sensing

  • Li, Xing Long;Xu, Min;Ren, Xian Dong;Pei, Yun Tian
    • Journal of the Optical Society of Korea
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    • 제16권3호
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    • pp.243-246
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    • 2012
  • An off-axis four-mirror-anastigmatic telescope is presented here which is composed of two aspheric surfaces and two spherical surfaces. The entrance pupil diameter is 290 mm and the stop is located at the primary mirror. The effective focal length is 900 mm. The strip field of view for the telescope is $15^{\circ}{\times}0.2^{\circ}$ and if the telescope is launched into an orbit about 400 km altitude, the observed range width will be more than 105 km within a scene without any other auxiliary scanning instrument. The spectral range can be as wide as from visual wave band to infrared wave band in the mirror system. This telescope can be used for environmental monitoring with different detectors whose pixel is adapted to the optical resolution. In this paper, the spectral range is chosen as 3.0 -5.0 ${\mu}m$, and center distance of the pixel is 30 ${\mu}m$. And the image quality is near the diffraction limit.

당뇨병환자와 정상인의 말초혈관혈류의 비선형적 운동계 분석에 대한 연구 (A Study of the Analysis of Characteristics of Nonlinear Dynamic System on Blood-Flow of Peripheral Blood-Vessel between Diabetic Patients and Control Subjects)

  • 김덕훈;최준영;이상훈;고한우;남상희
    • 대한의용생체공학회:학술대회논문집
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    • 대한의용생체공학회 1996년도 추계학술대회
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    • pp.363-367
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    • 1996
  • In general, the physiological systems have shown nonlinear complex phenomena. This study analyzes nonlinear characteristics of the flow of peripheral blood vessel dynamics in physiological systems using chaos theory. We performed this study by means of several quantity methods and power spectrum. The quantity methods are a phase space reconstruction and a poincare's map. And the power spectrum method is a conventional linear analysis. Experimental data have been acquired from examining 10 diabetic patients, and 10 control subjects in initial stable state. In acquisition experminetal data, we anlysized the differences of nonlinear characteristics between diabetic group and control group. The results of quality analysis methods showed the flow of peripheral blood vessel had the nonlinear and chaotic characteristics, screening a strange attractor on reconstructed phase space. In conclusion, the flow dynamics of peripheral blood vessel had a chaotic behavior of nonlinear dynamic systems, dynamic system, and differences of characteristic of nonlinear dynamic system.

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Image Plate로서의 X선 조사에 대한 Amorphous Selenium Plate 표면 Potential 특성 연구 (The Study for Characteristics between Amorphous Selenium Plate Surface Potential and X-ray Exposure by Image Plate)

  • 최준영;조승열;김명수;임종덕;김덕훈;남상희
    • 대한의용생체공학회:학술대회논문집
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    • 대한의용생체공학회 1996년도 춘계학술대회
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    • pp.41-44
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    • 1996
  • There are studied for filmness methods due to disadvantage of conventional X-ray system. Have high DQE, high SNR, amorphous selenium was investigated with image plate. In this point, characteristics of all amorphous selenium image plate was investigated to understand the relationship between the amount of the X-ray exposure and the superficial charge potential in this study. Specially, changes in charge at the surface of the amorphous selenium plate with respect to change of X-ray energy(KeV) was investigated. It was found that the surface charge potential at the amorphous selenium inclosed with respect to the increse in X-ray exposure and that the changed surface potential was a semilinearity in 12.5KeV - 22.5KeV range. Therefore, which suggests that these results call be applied to the development of X-ray image plate.

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Heterogeneous Computation on Mobile Processor for Real-time Signal Processing and Visualization of Optical Coherence Tomography Images

  • Aum, Jaehong;Kim, Ji-hyun;Dong, Sunghee;Jeong, Jichai
    • Current Optics and Photonics
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    • 제2권5호
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    • pp.453-459
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    • 2018
  • We have developed a high-performance signal-processing and image-rendering heterogeneous computation system for optical coherence tomography (OCT) on mobile processor. In this paper, we reveal it by demonstrating real-time OCT image processing using a Snapdragon 800 mobile processor, with the introduction of a heterogeneous image visualization architecture (HIVA) to accelerate the signal-processing and image-visualization procedures. HIVA has been designed to maximize the computational performances of a mobile processor by using a native language compiler, which targets mobile processor, to directly access mobile-processor computing resources and the open computing language (OpenCL) for heterogeneous computation. The developed mobile image processing platform requires only 25 ms to produce an OCT image from $512{\times}1024$ OCT data. This is 617 times faster than the naïve approach without HIVA, which requires more than 15 s. The developed platform can produce 40 OCT images per second, to facilitate real-time mobile OCT image visualization. We believe this study would facilitate the development of portable diagnostic image visualization with medical imaging modality, which requires computationally expensive procedures, using a mobile processor.

반도체레이저 여기 세라믹 Nd:YAG 레이저에서 Q-스위칭 동작 최적화 (Optimization of Q-switched Operation at a Laser-Diode Pumped Nd:YAG Ceramic Laser)

  • 신동준;김병태;김덕래
    • 한국광학회지
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    • 제19권4호
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    • pp.320-326
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    • 2008
  • 광섬유 연결 반도체레이저 여기 세라믹 Nd:YAG 레이저의 전기광학 Q-스위칭 출력 특성에 대해 연구하였다. 세라믹 Nd:YAG 레이저의 Q-스위칭은 여기원의 펄스폭 $1,000\;{\mu}s$, 출력 거울의 반사율 77% 및 지연시간 $985\;{\mu}s$에서 최적화되었다. 여기 에너지 17.9 mJ에서 0.35 mJ의 Q-스위칭된 출력 에너지와 약 4 ns의 펄스폭이 측정되어 1.9%의 출력 효율과 87.5 kW의 첨두 출력을 나타내었다.