• Title/Summary/Keyword: Mediator Effects

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Antioxidant Activity and Anti-inflammatory Effects of Salix Koreensis Andersson Branches Extracts (버드나무(Salix Koreensis Andersson) 가지 추출물의 항산화 및 항염증 효과)

  • Kim, Mi-Hye
    • Journal of the Korean Society of Food Culture
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    • v.33 no.2
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    • pp.104-111
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    • 2018
  • This study aims to compare and analyze a willow tree (Salix Koreensis andersson) extract's antioxidant and anti-inflammatory activity by investigating its: total polyphenol, flavonoid content, SOD-like activity, DPPH vitality. the willow tree was induced with LPS to determine its active anti-inflammatory effects. as a result, the willow methanol extract showed a higher total polyphenol and flavonoid content than those of willow distilled water extract, but the willow distilled water extract showed a higher SOD than that of willow methanol extract. in its DPPH scavenging ability, the willow methanol extract's antioxidant activity was higher than that of the willow distilled water extract. the willow extract's measurements such as the production of NO, inflammatory cytokine ($TNF-{\alpha}$, IL-6 measurement) were significantly reduced as its concentration level went down. according to the research outcomes, when induced, he will extract's macrophage produces mediator-like substances such as NO and inflammatory cytokine that can be used to alleviate the inflammatory response. therefore, the willow tree proved to be a useful raw plant material for the products designed to combat inflammatory activities due to its natural antioxidant and anti-inflammatory response substances such as NO and cytokine.

The Effects of the Safety Awareness and Safety Practice of the Day-Care Teacher according to the Presence of CCTV (CCTV 존재 여부가 보육교사의 안전의식과 안전실천에 미치는 영향)

  • Kwon, Mee-Rhan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.2
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    • pp.822-826
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    • 2012
  • This study practically analyzed the relationships of safety awareness and safety practice of the day-care teacher according to the presence of CCTV and in particular, made a practical analysis about whether safety awareness have mediation effects in the relationship between presence of CCTV and safety practice. As a result of T-test analysis, safety awareness and safety practice of the day-care teacher according to the presence of CCTV is different that has been verified. As a result of regression analysis, safety awareness were positively related to safety practice. That is to say, even the mediation effects that the presence of CCTV through safety awareness related to safety practice were verified. As a result, it was concluded that safety awareness factors didn't play mediator roles between presence of CCTV and safety practice.

The Effects of Emotional Labor on Burnout: The Moderating and Mediating Effects of Flourishing in Child Care Teachers (어린이집 교사의 정서노동과 소진 간 관계에서 행복플로리시의 조절 및 매개효과)

  • Lee, Ji Yeun;Kim, Hee Yeol
    • Korean Journal of Child Studies
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    • v.37 no.4
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    • pp.169-179
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    • 2016
  • Objective: This study investigated the moderating and mediating effects of flourishing among child-care teacher's emotional labor and burnout. Methods: The participants included 243 child-care teachers in daycare centers in Jeju. To verify moderating effect of flourishing in relation between surface acting and burnout, 2-way ANOVA was used. To verify mediating effect of flourishing in relation between deep acting and burnout, the hierarchical regression and bootstrapping analyses were used. Results: First, the surface acting of emotional labors showed significantly positive effect with burnout and the deep acting of emotional labors shows significantly negative effect with burnout. And the surface acting of emotional labors shows significantly negative effect with flourishing and the deep acting of emotional labors shows significantly positive effect with flourishing. Also the flourishing shows significantly negative effect with burnout. Second, it was revealed that the flourishing plays a role as moderator in relation between surface acting and burnout. Finally, it was revealed that the flourishing plays a role as mediator in relation between deeping acting and burnout. Conclusion: This study illustrates that flourishing acts as differently in relation to emotional labor (surface acting/deep acting) and burnout.

The Effects of Parental Psychological Control, Dysfunctional Perfectionism, and Self-Conscious Emotions on Depression in Adolescents (부모의 심리적 통제와 고등학생의 역기능적 완벽주의 및 자의식 정서가 우울에 미치는 영향)

  • Kim, Hye-In;Doh, Hyun-Sim;Chee, Yeon-Kyung
    • Korean Journal of Child Studies
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    • v.32 no.4
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    • pp.15-36
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    • 2011
  • This study examined the effects of parental psychological control, dysfunctional perfectionism, and self-conscious emotions on depression in adolescents. The sample consisted of 471 adolescents (212 boys, 259 girls) attending high schools in Seoul. The results from Structural Equation Modeling indicated that dysfunctional perfectionism and self-conscious emotions mediated the impact of parental psychological control on depression only in the mother-daughter relationship, such that with mothers' greater psychological control, girls experienced higher levels of dysfunctional perfectionism and self-conscious emotions, and reported higher depression scores. Similarly, dysfunctional perfectionism functioned as a mediator in the association between parental psychological control and adolescent depression. This tends to support findings from previous studies emphasizing the importance of same sex parent-adolescent relationships. Dysfunctional perfectionism also had the largest direct effect of all variables analyzed on depression. Parental psychological control did not show statistically significant effects on self-conscious emotions for either boys or girls. These findings suggest that interventions designed to promote adolescents' mental well-being should focus on parenting of the same sex parent as well as adolescent cognitive characteristics.

Influence of Parents' Rearing Attitudes Perceived by Bullied Children on Bullying: Ego-Resilience Mediation (집단따돌림 피해 아동이 지각하는 부모의 양육태도가 집단따돌림에 미치는 영향: 자아탄력성의 매개효과)

  • Choi, Yeon-Hee;Kim, Na-Young
    • Research in Community and Public Health Nursing
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    • v.24 no.2
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    • pp.214-224
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    • 2013
  • Purpose: This study was conducted to examine effects of parents' rearing attitudes perceived by bullied children. The focus in this study was on mediating effects of ego-resilience. Methods: Data were collected from 202 bullied elementary school students in grade years 5 and 6. The data were analyzed by using descriptive statistics, correlation analysis and structural analysis with the SPSS/WIN 19.0 program and Amos 19.0. Results: First, significant positive relations between parents' rearing attitudes and ego-resilience, significant negative relations between ego-resilience and bullying, and between parents' rearing attitude and bullying were found. Second, the effects of ego-resilience as a mediator between perceived parents' rearing attitudes and bullying were significant statistically. Conclusion: The findings suggest that educational programs for parents are needed to improve parents' perception of the importance of their rearing attitudes toward bullying and nursing intervention programs for bullied children should be developed to increase their ego-resilience.

Scavenging Effects of Hydroxycinnamic Acids on Paraquat Induced Pulmonary Toxicity (III) (Paraquat 유도 페독성에 대한 Hydroxycinnamic Acid계 화합물의 독성 경감 효과 (III))

  • 최병기;오은정;정세영
    • Environmental Analysis Health and Toxicology
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    • v.14 no.3
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    • pp.95-101
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    • 1999
  • The scavenging effects of two hyaroxycinnamic acids such as caffeic acid and chlorogenic acid on paraquat induced pulmonary toxicity were investigated. The results are summerized as follows: 1. In the 5-lipoxygenase assay, caffeic acid and chlorogenic acid inhibited the enzyme activities whose inhibition concentration (IC$\_$50/) were 4.1 and 9.6 ${\mu}$M respectively. 2. To evaluate the antiinflammatory effects on mediator related to the mechanism of inflammation, ADP-induced platelet aggregation assay and histamine degranulation assay were used. Caffeic acid and chlorogenic acid inhibited on ADP-induced platelet aggregation and histamine release at a concentration dependent manners. 3. Arachidonic acid-induced ear edema were inhibited by administration of caffeic acid and chlorogenic acid. 4. Cytologicad analysis of branchoalveolar lavage fluid (BALF) which was the useful tool for detection of an inflammatory response in the lungs of animals intoxicated with chemicals were used. Alveolar macrophages and neutrophils in BALF, as well as the protein content and the LDH activity in BALF supernatant increased by intoxication of paraquat, but decreased by administration of caffeic acid and chlorogenic acid. Therefore, two hydroxyeinnamic acids tested were the useful candidates for scavenger and antiinflammatory agents on paraquat induced pulmonary toxicity.

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The Effects of Parental Socioeconomic Status on Preschoolers' Social Competence and Cognitive Development : The Role of Parental Warmth and Home Learning Environment (부모의 사회경제적 지위가 유아의 사회적 유능성 및 인지발달에 미치는 영향 : 부모 온정성과 교육적 가정환경의 매개효과)

  • Chang, Young Eun
    • Korean Journal of Child Studies
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    • v.36 no.6
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    • pp.1-21
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    • 2015
  • This study was aimed at examining the paths through which family socioeconomic status as indicated by family income and parental education influenced preschool-aged children's socioemotional and cognitive development through the mediating role of parental warmth and the home learning environment. The study made use of data from 1,080 families who participated in the 5th wave of the Panel Study on Korean Children, when their children were approximately 4 years of age. Structural equation modeling analysis revealed that the models, including both parental warmth and the home learning environment did not fit the data well. The effects of warmth on social competence and cognitive development were not statistically significant. The modified models, using the home learning environment as a mediator between family SES and child's developmental outcomes showed that higher level of family income and parental education predicted a more cognitively stimulating home environment, which in turn, predicted a child's greater levels of social competence and positive cognitive development. The social competence of preschool-aged children again significantly predicted their cognitive development. The mediating effects of the home learning environment were statistically supported.

Simple power analysis in causal mediation models for a dichotomous outcome based on the mediation proportion

  • Kim, Young Min;Cologne, John Bennett;Cullings, Harry Michael
    • Journal of the Korean Data and Information Science Society
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    • v.28 no.3
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    • pp.669-684
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    • 2017
  • Mediation models are widely used in many fields of research and have recently gained attention in epidemiology. The mediation proportion is a standard measure to evaluate what part of the total exposure effect on an outcome may be explained by a particular mediator and to examine how important that pathway is relative to the overall exposure effect. A common question is how large a sample size is needed to achieve high statistical power or, equivalently, what magnitude of effect can be detected. Current power and sample size calculations for mediation analysis are limited and additional research is needed. We therefore propose a computer-intensive power analysis using the mediation proportion. We conduct simulation studies to calculate statistical powers and sample sizes. And then, we illustrate our power analysis using an example from the Adult Health Study of atomic-bomb survivors and demonstrate that the method is relatively straightforward to understand and compute.

Effects of Fathers' Parental Involvement and Social Support on Parenting Stress of Mothers with Infants: Mothers' Psychological Characteristics as a Mediator (아버지 양육참여와 사회적 지지가 영아기 어머니의 양육스트레스에 미치는 영향: 어머니 심리특성의 매개효과)

  • Kim, Sang Lim;Park, Chang Hyun
    • The Korean Journal of Community Living Science
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    • v.27 no.3
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    • pp.451-464
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    • 2016
  • This study had two purposes. One was to investigate the interrelations between the mothers' parenting stress and fathers' parental involvement, social support, and the mothers' psychological characteristics. The other was to prove that the fathers' parental involvement and social support have an effect on the mothers' parenting stress, and that these effects are mediated by the mothers' psychological characteristics. For this purpose, the data of 1,754 2-year-olds and their mothers from the 2010 Panel Study on Korean Children were analyzed using PASW ver. 21.0 and AMOS ver. 23.0 to carry out descriptive statistics, correlation co-efficiencies, and structural equation model, along with the Sobel test. The results showed that the mothers' parenting stress had significant, negative correlations with the fathers' parental involvement, social support, and mothers' positive psychological characteristics. The findings also proved that not only the fathers' parental involvement, but also social support, had significant effects on the mothers' parenting stress, and that the mothers' positive psychological characteristics mediated these relations.

Children's Aggressive/Prosocial Behaviors and Maternal Parenting Behaviors: Children's Emotional Regulation as Mediator (어머니 양육행동이 아동의 공격적 행동 및 친사회적 행동에 미치는 영향: 아동의 정서조절을 매개로 하여)

  • Kim, Ji-Hyun
    • Journal of the Korean Home Economics Association
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    • v.48 no.2
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    • pp.13-22
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    • 2010
  • This study explored mediating effects of children's emotional regulation between maternal parenting behaviors and children's aggressive/prosocial behaviors. The participants were 1,187 4th, 5th, 6th grade children and their mothers from two elementary schools in Korea. The Maternal Parenting Behaviors Scale(Kim, 2006), the Emotional Regulation Scale(Lee, 1997), and a peer-nomination measure(Crick, 1995; Crick & Grotpeter, 1995) were used. Collected data were subjected to descriptive statistical analysis, Pearson's productive correlation and regression using SPSS(Ver 12.0). Findings revealed that children's self-emotional regulation mediated the effects of mother's physical punishment on children's aggressive behaviors, while children's other-emotional regulation mediated the effect of mother's warm-encouragement, mediation-supervision, and inconsistency on children's prosocial behaviors. In conclusion, children's emotional regulation mediates the effects of maternal parenting behaviors on children's aggressive/prosocial behaviors.