• Journal of Chest Surgery
• /
• 제28권12호
• /
• pp.1192-1196
• /
• 1995

As reported in the literature, extraskeletal mesenchymal chondrosarcoma is a rare malignant tumor of soft tissue, and it has a unique, distinctive histologic picture and poor prognosis.The common sites are the orbit, the cranial dura mater, the neck, the thigh, the leg, the chest wall, and the retroperitoneum. Radical excision of the tumor seems to be the primary treatment.We report experience with a very rare case of extraskeletal mesenchymal chondrosarcoma in the posterior mediastinum.

• Journal of Chest Surgery
• /
• 제28권6호
• /
• pp.644-648
• /
• 1995

Intrapulmonary teratoma is rare : only 30 cases have been reported in the world literature. We had experienced a case of benign intrapulmonary teratoma originated from anterior mediastinum associated with broncho-tumorous fistula, which was treated with En bloc removal of tumor and right middle lobectomy. Post-operative course was not eventful.

• Clinical and Experimental Pediatrics
• /
• 제58권10호
• /
• pp.386-391
• /
• 2015

Purpose: To evaluate the outcomes and prognostic factors in children with extracranial germ cell tumors (GCTs) treated at a single institution. Methods: Sixty-six children diagnosed with extracranial GCTs between 1996 and 2012 were included in the study. Primary treatment was surgical excision, followed by six cycles of cisplatin-based chemotherapy. The survival rates were compared according to the International Germ Cell Cancer Cooperative Group classification used for GCTs in adults to validate the classification guidelines for GCTs in children. Results: The median patient age was 4.4 years. In 34 patients (51.5%), the primary tumor site was the gonad. Extragonadal GCTs were detected in 32 patients. The 5-year overall survival and event-free survival (EFS) were $92.0%{\pm}3.5%$ and $90.4%{\pm}3.7%$, respectively. In univariate analysis, tumor histology, metastasis, and elevated alpha-fetoprotein were not prognostic factors in children with extracranial GCTs. However, EFS was poorer in patients with mediastinal disease (n=12, $66.7%{\pm}13.6%$) than in those with nonmediastinal disease (n=54, $96.0%{\pm}2.8%$) (P=0.001). The 5-year EFS was lower in patients older than 10 years, (n=21, $80.0%{\pm}8.9%$) compared with those younger than 10 years (n=45, $95.2%{\pm}3.3%$) (P=0.04). Multivariate analysis identified the mediastinal tumor site as the only independent prognostic factor. Conclusion: The prognosis of children with extracranial GCTs was favorable. However, nongerminomatous mediastinal tumors were associated with poor survival in children. Further research is needed to improve the prognosis of children with malignant mediastinal GCTs.

• Tuberculosis and Respiratory Diseases
• /
• 제66권6호
• /
• pp.482-485
• /
• 2009

종격동은 다양한 기관들이 밀집되어 있는 구조라서 종양 등 질병이 발생하더라도 위치상 심장이나 대혈관의 음영과 중첩되어 보이기 때문에 단순 흉부 X-선 촬영상 정상 소견으로 오인할 수 있다. 종격동 종양의 경우 주위조직의 침범 여부나 주위 림프절 크기 이외에도 환자의 연령, 종양의 크기 및 위치, 환자의 증세 유무가 중요한 고려사항이다. 저자들은 흉부 불쾌감이 지속되어 내원한 56세 여자 환자에게서 단순 흉부 X-선 사진의 면밀한 관찰을 통해 기관 분지부의 종격동 종양을 발견한 증례를 통해, 다시 한번 단순 흉부 X-선 촬영의 진단적인 중요성을 임상의들에게 환기시키고자 한다.

• Journal of Chest Surgery
• /
• 제30권4호
• /
• pp.408-412
• /
• 1997

1986년 4월부터 1996년 4월까지 원발성 종격동 종양 및 낭종 27례를 분석하였다. 총 27명으로 남자가 9명 여자가 18명으로 주증상은 흉부불쾌감(8/27)이고 대부분이 무증상이였다(17/27). 가장 흔한 원발성 종양은 신경 종으로서 9례 였으며, 악성 인 경우는 총 3례로서 모두 흉선종이었다. 26례 에서 완전 적출을 하였고 수술후 합병증은 없었다.

• 대한세포병리학회지
• /
• 제16권1호
• /
• pp.41-46
• /
• 2005

Carcinoid tumors of the thymus are vanishingly rare, and the characteristic cytologic findings of this condition have never before been reported in Korea. Recently, we encountered a 58-year-old woman who had been suffering from general weakness and weight loss for several months. Radiological imaging revealed a large anterior mediastinal mass. A fine needle aspiration biopsy (FNAB) of the mass showed predominantly scattered single cells, as well as some loose clusters of small cells with scanty cytoplasm. Some of these small cells exhibited plasmacytoid features, with moderately granular cytoplasm. We also discuss the cytological differential diagnosis between thymic carcinoid and other mediastinal tumors.

• Clinical and Experimental Pediatrics
• /
• 제53권1호
• /
• pp.103-105
• /
• 2010

흉선 지방종은 중격동 전방에서 유례하는 매우 드문 종양이다. 대부분의 환자들은 증상이 없어 다른 이유로 시행한 검사상에서 우연히 발견되는 경우가 많다. 저자들은 13세된 여아에서 발견되어 수술한 흉선 지방종 환자를 경험하였기에 이를 보고하는 바이다.

• Journal of Chest Surgery
• /
• 제35권7호
• /
• pp.560-563
• /
• 2002

심흉부 수술 후에 발생하는 횡격막 신경 손상으로 인한 편측 횡격막 마비는 드물지 않게 발생하는 질환으로 증상 없이 방사선학적 비정상 소견만을 보이는 것에서 심한 폐기능 장애와, 심지어는 폐기능이 저하되어 있는 환자에서는 사망을 초래하기도 하는 질환이다. 이러한 증상이 발현된 편측 횡격막 마비시, 마비된 편측 횡격막의 주름성형술이 가장 효과적인 치료방법으로 알려져 있다. 본원에서는 천식의 병력이 있는 38세의 남자 환자의 전종격동에 발생한 종양 절제시 발생한 우측 횡격막 신경 손상에 대해 비복 신경을 이용한 횡격막 신경 재건술을 시행하여 술후 10개월째 시행한 단순 흉부 방사선 검사상 좋은 결과를 얻었기에 간략한 문헌 고찰과 함께 보고하는 바이다.

• Journal of Chest Surgery
• /
• 제45권3호
• /
• pp.192-195
• /
• 2012

Leiomyosarcoma of the mediastinum and primary leiomyosarcoma of the spine are exceedingly rare. In most cases, spinal leiomyosarcoma is metastatic. In this report, we describe the case of a 58-year-old man who presented with a large leiomyosarcoma of the posterior mediastinum that extended into the adjacent spinal canal. The tumor was completely resected from the mediastinum, but only subtotally removed from the spinal canal because the spinal mass had tightly invaded the spinal cord. Because the patient's postoperative condition was poor, no adjuvant radiotherapy or chemotherapy was administered. He expired 3 months after the surgery due to relapse; the spinal and mediastinal tumor remained at the preoperative size.

• Journal of Yeungnam Medical Science
• /
• 제29권1호
• /
• pp.45-47
• /
• 2012

Osteochondroma is a common bone tumor but a rare tumor in the rib. It is often asymptomatic and observed incidentally. This is a case report of a 49-year-old woman with an osteochondroma mimicking a mediastinal mass in hereditary multiple exostoses. The chest X-ray and computed tomography (CT) scans revealed the bony density feature of the mass. Surgical excision confirmed that the lesion was an osteochondroma.