Pine Needle Aspiration Cytology of a Thymic Carcinoid Tumor - A Case Report -

가슴샘 카르시노이드종양의 세침흡인 세포소견 - 1예 보고 -

  • Oh, Young-Ha (Department of Pathology, College of Medicine, Hanyang University) ;
  • Jang, Ki-Seok (Department of Pathology, College of Medicine, Hanyang University) ;
  • Song, Young-Soo (Department of Pathology, College of Medicine, Hanyang University) ;
  • Lee, Chul-Burm (Department of Thoracic Surgery, College of Medicine, Hanyang University) ;
  • Park, Choong-Ki (Department of Radiology, College of Medicine, Hanyang University) ;
  • Park, Moon-Hyang (Department of Pathology, College of Medicine, Hanyang University) ;
  • Park, Yong-Wook (Department of Pathology, College of Medicine, Hanyang University)
  • 오영하 (한양대학교 의과대학 병리학교실) ;
  • 장기석 (한양대학교 의과대학 병리학교실) ;
  • 송영수 (한양대학교 의과대학 병리학교실) ;
  • 이철범 (한양대학교 의과대학 흉부외과학교실) ;
  • 박충기 (한양대학교 의과대학 진단방사선과학교실) ;
  • 박문향 (한양대학교 의과대학 병리학교실) ;
  • 박용욱 (한양대학교 의과대학 병리학교실)
  • Published : 2005.05.31

Abstract

Carcinoid tumors of the thymus are vanishingly rare, and the characteristic cytologic findings of this condition have never before been reported in Korea. Recently, we encountered a 58-year-old woman who had been suffering from general weakness and weight loss for several months. Radiological imaging revealed a large anterior mediastinal mass. A fine needle aspiration biopsy (FNAB) of the mass showed predominantly scattered single cells, as well as some loose clusters of small cells with scanty cytoplasm. Some of these small cells exhibited plasmacytoid features, with moderately granular cytoplasm. We also discuss the cytological differential diagnosis between thymic carcinoid and other mediastinal tumors.

Keywords

References

  1. Simosato Y, Mukai K. Tumors of the Mediastinum, 3rd Series. Washington, D.C.: Armed Forces Institute of Pathology, 1997;158-83
  2. Rosai J, Higa E. Mediastinal endocrine neoplasm, of probable thymic origin, related to carcinoid tumor. Cancer 1972;29: 1061-74 https://doi.org/10.1002/1097-0142(197204)29:4<1061::AID-CNCR2820290456>3.0.CO;2-3
  3. Wang DY, Kuo SH, Chang DB, Yang PC, Lee YC, Hsu HC, et al. Fine needle aspiration cytology of thymic carcinoid tumor. Acta Cytol 1995;39:423-7
  4. Collins BT, Cramer HM. Fine needle aspiration cytology of carcinoid tumors. Acta Cytol 1996;40:695-707 https://doi.org/10.1159/000333942
  5. Hallmann RS, Schneeweiss LG, Correa E, Zamora J. Fine needle aspiration biopsy of thymic carcinoid tumor: a case with immunocytochemical correlation. Acta Cytol 1998; 42:1042-3 https://doi.org/10.1159/000331955
  6. Fekete PS, Cohen C, DeRose PB. Pulmonary spindle cell carcinoid. Needle aspiration biopsy, histologic and immunohistochemical findings. Acta Cytol 1990;34:50-6
  7. 이연수, 박경신, 최영진, 김석진, 김병기, 심상인, 폐의 비정형 유암종의 세침흡인 세포학적 소견-2예 보고- 대한세포병리학회지 1997;8:76-82