• Tuberculosis and Respiratory Diseases
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• v.43 no.5
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• pp.709-719
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• 1996

Background: Surgical resection is the only way to cure non-small cell lung cancer(NSCLC) and the prognosis of NSCLC in patients who undergo a complete resection is largely influenced by the pathologic stage. After surgical resection, recurrences in distant sites is more common than local recurrences. An effective postoperative adjuvant therapy which can prevent recurrences is necessary to improve long tenn survival Although chemotherapy and radiotherapy are still the mainstay in adjuvant therapy, the benefits of such therapies are still controversial. We initiated this retrospective study to evaluate the effects of adjuvant therapies and analyze the prognostic factors for survival after curative resection. Method: From 1990 to 1995, curative resection was perfomled in 282 NSCLC patients with stage I, II, IIIa, Survival analysis of 282 patients was perfonned by Kaplan-Meier method. The prognostic factors, affecting survival of patients were analyzed by Cox regression model. Results: Squamous cell carcinoma was present in 166 patients(59%) ; adenocarcinoma in 86 pmients(30%) ; adenosquamous carcinoma in II parients(3.9%); and large cell undifferentiated carcinoma in 19 patients(7.1%). By TNM staging system, 93 patients were in stage I; 58 patients in stage II ; and 131 patients in stage rna. There were 139 postoperative recurrences which include 28 local and 111 distant failures(20.1% vs 79.9%). The five year survival rate was 50.1% in stage I ; 31.3% in stage II ; and 24.1% in stage IIIa(p <0.0001). The median survival duration was 55 months in stage I ; 27 months in stage II ; and 16 months in stage rna. Among 131 patients with stage rna, the median survival duration was 19 months for 81 patients who received postoperative adjuvant chemotherapy only or cherne-radiotherapy and 14 months for the other 50 patients who received surgery only or surgery with adjuvant radiotherapy(p=0.2982). Among 131 patients with stage IIIa, the median disease free survival duration was 16 months for 21 patients who received postop. adjuvant chemotherapy only and 4 months for 11 patients who received surgery only(p=0.0494). In 131 patients with stage IIIa, 92 cases were in N2 stage. The five year survival rate of the 92 patients with N2 was 25% and their median survival duration was 15 months. The median survival duration in patients with N2 stage was 18 months for those 62 patients who received adjuvant chemotherapy and 14 months for the other 30 patients who did not(p=0.3988). The median survival duration was 16 months for those 66 patients who received irradiation and 14 months for the other 26 patients who did not(p=0.6588). We performed multivariate analysis to identify the factors affecting prognosis after complete surgical resection, using the Cox multiple regression model. Only age(p=0.0093) and the pathologic stage(p<0.0001) were significam prognostic indicators. Conclusion: The age and pathologic stage of the NSCLC parients are the significant prognostic factors in our study. Disease free survival duration was prolonged with statistical significance in patients who received postoperative adjuvant chemotherapy but overall survival duration was not affected according to adjuvant therapy after surgical resection.

• Journal of Home Health Care Nursing
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• v.25 no.2
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• pp.209-218
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• 2018

Purpose: This study is to identify the health promoting behaviors, health belief, and self-efficacy of visiting nurses working for the Health Visiting Project in Seoul and to determine the predictors of influencing health promoting behaviors. Methods: Data were collected from an online survey of 496 visiting nurses form 25 districts in Seoul. Using SPSS ver. 24, the study performed descriptive statistics, t-test, one-way ANOVA, correlations, and stepwise multiple regression. Results: The mean scores for health promoting behaviors and self-efficacy were slightly higher than that of the median, whereas health belief showed in the median. The factors influencing health promoting behavior were perceived barriers, perceived sensitivity, self-efficacy, and age. These variables explained 36.0% of health promoting behaviors(F=60.62, p<.05). Conclusion: To prevent illness and to promote the health of the population, the visiting nurse mainly performs health screening, health education and counseling. To fulfill these responsibilities, the visiting nurse should be healthy and perform health promoting behaviors well, effectively serving as a model for their clients. Most of the visiting nurses were middle-aged, thus, it is necessary to strengthen health promotion activities that manage physical and psychological health at the individual level.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.47-47
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• 2023

Drought occurs due to lack of water resources over an extended period and its intensity has been magnified globally by climate change. In recent years, drought over South Korea has also been intensed, and the prediction was inevitable for the water resource management and water industry. Therefore, drought forecasting over South Korea was performed in the current study with the following procedure. First, accumulated spring precipitation(ASP) driven by the 93 weather stations in South Korea was taken with their median. Then, correlation analysis was followed between ASP and Df4m, the differences of two pair of the global winter MSLP. The 37 Df4m variables with high correlations over 0.55 was chosen and sorted into three regions. The selected Df4m variables in the same region showed high similarity, leading the multicollinearity problem. To avoid this problem, a model that performs variable selection and model fitting at once, least absolute shrinkage and selection operator(LASSO) was applied. The LASSO model selected 5 variables which showed a good agreement of the predicted with the observed value, R²=0.72. Other models such as multiple linear regression model and ElasticNet were also performed, but did not present a performance as good as LASSO. Therefore, LASSO model can be an appropriate model to forecast spring drought over South Korea and can be used to mange water resources efficiently.

• Journal of Preventive Medicine and Public Health
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• v.52 no.2
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• pp.140-144
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• 2019

Objectives: Investigating the survival of patients with cancer is vitally necessary for controlling the disease and for assessing treatment methods. This study aimed to compare various statistical models of survival and to determine the survival rate and its related factors among patients suffering from lung cancer. Methods: In this retrospective cohort, the cumulative survival rate, median survival time, and factors associated with the survival of lung cancer patients were estimated using Cox, Weibull, exponential, and Gompertz regression models. Kaplan-Meier tables and the log-rank test were also used to analyze the survival of patients in different subgroups. Results: Of 102 patients with lung cancer, 74.5% were male. During the follow-up period, 80.4% died. The incidence rate of death among patients was estimated as 3.9 (95% confidence [CI], 3.1 to 4.8) per 100 person-months. The 5-year survival rate for all patients, males, females, patients with non-small cell lung carcinoma (NSCLC), and patients with small cell lung carcinoma (SCLC) was 17%, 13%, 29%, 21%, and 0%, respectively. The median survival time for all patients, males, females, those with NSCLC, and those with SCLC was 12.7 months, 12.0 months, 16.0 months, 16.0 months, and 6.0 months, respectively. Multivariate analyses indicated that the hazard ratios (95% CIs) for male sex, age, and SCLC were 0.56 (0.33 to 0.93), 1.03 (1.01 to 1.05), and 2.91 (1.71 to 4.95), respectively. Conclusions: Our results showed that the exponential model was the most precise. This model identified age, sex, and type of cancer as factors that predicted survival in patients with lung cancer.

• Journal of Korean Society of Transportation
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• v.29 no.4
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• pp.103-111
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• 2011

The speed is one of the significant factors affecting accident occurrence. In particular, freeway accidents are highly associated with the speed because vehicles travel on the freeway at higher speed leading to greater potential of severer injury. Efforts attempting to relating speed with accident occurrence have not been significantly made in Korea. The objective of this study is to model the relationship between speed and accident rate on freeways. Loop detector data and accident data obtained from a stretch of Kyungboo freeway during the recent five years, 2005-2009, were used to establish the model. Multiple linear regression analyses showed that median, minimum and standard deviation of speed were contributing variables in the model. The statistical significance identified by the analyses supports the feasibility of the model in evaluating various transportation policies and operations strategies in terms of traffic safety.

• Radiation Oncology Journal
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• v.30 no.4
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• pp.153-157
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• 2012

Purpose: There has been no definite consensus on standard treatment, either local or systemic, for the Kaposi's sarcoma (KS). Radiotherapy (RT) can be a good local therapeutic choice especially in non-AIDS associated KS (NAKS) for its indolent behavior. Materials and Methods: Medical records of 17 KS patients treated with RT at the Seoul National University Hospital from February 1998 to January 2012 were retrospectively reviewed. One human immunodeficiency virus (HIV)+ patient with 3 lesions was excluded. The total number of the lesion was 23 among the 16 patients. The median follow-up period was 27.9 months. Correlation between response and variables was analyzed using the logistic regression model. Median age of the patients was 75 years. All the 23 lesions were located at the extremities. Fourteen (61%) of those had pain or local swelling as the initial presentation. Ten patients had possible causes of immunodeficiency and were regarded as iatrogenic, and other 6 were classic KS. Median dose of RT was 36 Gy. Results: No KS-related death was observed. Excluding 2 with short-term follow-up only, complete response and partial response were obtained in 2 (9%) and 19 (73%) lesions, respectively. Of those, 3 lesions underwent local progression. Six had out-of-field recurrence after RT. Symptom improvement was achieved in 13 (93%) of 14 patients. Grade 2 skin toxicities were found in 9 lesions but all got improvement after treatment. When divided into responsive and progressive group, free from progression was not related to any of the possible variables. Conclusion: RT is effective in local control of NAKS resulting great response rate.

• Journal of the Korean Society of Safety
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• v.27 no.3
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• pp.153-160
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• 2012

Various social problems such as traffic congestion, car accidents and environmental problems(air pollution, noises etc.) have been happening in the Seoul metropolitan area that has the car oriented traffic system providing cars continuously. Along with this, the financial burden caused by current oil price anxiety made paradigm shift from caroriented to public transportation-oriented. Its typical example is an arterial branch bus system changing(bus lane through the center of main road) started in Seoul in July, 2004. But study on safety analysis of bus lane and characteristic of accidents are not sufficient enough to now. The bus lanes are expanded to provide roads for better traffic operation and accidents between buses and pedestrians or ordinary vehicles are considered main problems. This study divided each bus route of median bus lane(bus-only lane through the center of main roads) and bus lane at roadside by intersection and collected and analysed data about influence variables of bus accidents chosen in each section. We constructed a logistic model using collected data. As a result, bus lane at roadside are used by both buses and other kinds of vehicles differently from median bus lane and showed such characteristic in accident influence. Therefore access management to factors causing conflict and improvement of operation management are required. In case of median bus lane, the more buses moving general vehicle lane and traffic volume of section were, the more accidents happened. In case that stop line of center lane is not backward, view blocking of vehicles turning left caused accidents.

• International Journal of Highway Engineering
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• v.15 no.2
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• pp.131-138
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• 2013

PURPOSES : The intents of the study are to identify the accident factors and to demonstrate the potentials of tobit model as a tool to study the number of accidents on arterial roads segments. METHODS : This paper uses a tobit regression as a methodology to analyze the factors affecting the number of accidents. In pursuing the above goal, this study gives particular attentions to analyzing the data of 2,446 accidents (1,610 in major arterial roads and 836 in minor arterial roads) occurred on arterial roads in 2007 to 2010. RESULTS : First, 3 accident models which were classified by total arterial roads, major arterial roads and minor arterial roads, and were all statistically significant were developed. Second, the exclusive right-turn lane as common variable, and the number of accident, traffic volume, number of lanes, link length, rate of median, number of entrances, number of pedestrian crossings, number of curves, number of bus stops and exclusive left-turn as specific variables of the models were selected. Finally, the paired sample t-test could not be rejected the null hypotheses of three types of models. CONCLUSIONS : Using data from vehicle accidents on arterial roads, the estimation results show that many factors related to roadway geometrics and traffic characteristics significantly affect to the number of accidents.

• The Journal of Korean Academic Society of Nursing Education
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• v.27 no.1
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• pp.5-15
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• 2021

Purpose: This study aimed to provide a systematic review and meta-analysis of research on flipped learning effects applied to university students. Methods: The random effect model was applied to 21 papers to calculate the effect size. To verify the moderation effect, a meta regression analysis and meta ANOVA were performed. Publication bias was verified through a funnel plot, and then an Egger's regression test was conducted. Results: The overall average effect size was .69 (95% CI: .51-.87), showing a median effect size, which was statistically significant. The outcome variables were in the order of learning motivation (Hedges' g=.83), self-directed learning (Hedges' g=.78), learning achievement (Hedges' g=.66), and efficacy (Hedges' g=.50), which were statistically significant. Conclusion: Flipped learning was found to be statistically significant in improving self-directed learning, learning motivation, efficacy, and learning achievement amng university students. It is suggestd that this method be actively applied in university education.

• Journal of Korean Society of Water and Wastewater
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• v.12 no.3
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• pp.99-106
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• 1998

This paper presents a procedure for determining the design rainfall depth and the design rainfall intensity at Incheon city area in Korea. In this study the eight probability distributions are considered to estimate the probable rainfall depths for 11 different durations. The Kolmogorov - Smirnov test and the Chi-square test are adopted to test each distribution. The probable rainfall intensity formulas are then determined by i) the least squares (LS) method, ii) the least median squares (LMS) method, iii) the reweighted least squares method based on the LMS (RLS), and iv) the constrained regression (CR) model. The Talbot, the Sherman, the Japanese, and the Unified type are considered to determine the best type for the Incheon station. The root mean squared (RMS) errors are computed to test the formulas derived by four methods. It is found that the Unified type is the most reliable and that all methods presented herein are acceptable for determining the coefficients of rainfall intensity formulas from an engineering point of view.