• Korean Journal of Clinical Laboratory Science
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• v.46 no.4
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• pp.136-139
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• 2014

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the severe nosocomial infectious agents. The traditional diagnostic methods including biochemical test, antibiotic susceptibility test and PCR amplification are time consuming and require much work. The Surface enhanced Raman spectroscopy (SERS) biosensor is a rapid and powerful tool for analyzing the chemical composition within a single living cell. To identify the biochemical and genetic characterization of clinical MRSA, all isolates from patients were performed with VITEK2 gram positive (GP) bacterial identification and Antibiotic Susceptibility Testing (AST). Virulence genes of MRSA also were identified by DNA based PCR using specific primers. All isolates, which were placed on a gold coated nanochip, were analyzed by a confocal Raman microscopy system. All isolates were identified as S. aureus by biochemical tests. MRSA, which exhibited antibiotic resistance, demonstrated to be positive gene expression of both femA and mecA. Furthermore, Raman shift of S. aureus and MRSA (n=20) was perfectly distinguished by a confocal Raman microscopy system. This novel technique explained that a SERS based confocal Raman microscopy system can selectively isolate MRSA from non-MRSA. The study recommends the SERS technique as a rapid and sensitive method to detect antibiotic resistant S. aureus in a single cell level.

• Korean Journal of Computational Design and Engineering
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• v.17 no.5
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• pp.364-374
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• 2012

In this paper, we proposed a data structure to represent structural components of solid rocket motors (SRM) in an automated design program. To propose the data structure, we searched the necessary functions for the automated design program should have. In order to design the structural components of solid rocket motors sufficiently with a design program, it should have the functions to represent the shapes of the components, the drawing and analysis models, the design variables, various product structures, interferences, characteristic properties, design equations, and tightening sets. By modifying the data structure of an element object that is a general purpose data structure to represent a general component of a product, a new data structure was proposed to satisfy all the necessary functions with optimum. Finally, a design program for the structural components of solid rocket motors was developed successfully with the proposed data structure.

• Journal of Information Processing Systems
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• v.17 no.3
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• pp.615-629
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• 2021

With the development of mobile edge computing, how to utilize the computing power of edge computing to effectively and efficiently offload data and to compute offloading is of great research value. This paper studies the computation offloading problem of multi-user and multi-server in mobile edge computing. Firstly, in order to minimize system energy consumption, the problem is modeled by considering the joint optimization of the offloading strategy and the wireless and computing resource allocation in a multi-user and multi-server scenario. Additionally, this paper explores the computation offloading scheme to optimize the overall cost. As the centralized optimization method is an NP problem, the game method is used to achieve effective computation offloading in a distributed manner. The decision problem of distributed computation offloading between the mobile equipment is modeled as a multi-user computation offloading game. There is a Nash equilibrium in this game, and it can be achieved by a limited number of iterations. Then, we propose a distributed computation offloading algorithm, which first calculates offloading weights, and then distributedly iterates by the time slot to update the computation offloading decision. Finally, the algorithm is verified by simulation experiments. Simulation results show that our proposed algorithm can achieve the balance by a limited number of iterations. At the same time, the algorithm outperforms several other advanced computation offloading algorithms in terms of the number of users and overall overheads for beneficial decision-making.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.4187-4190
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• 2012

Aims and Background: To evaluate the efficacy of a combination of aprepitant and conventional antiemetic therapy in patients with advanced or recurrent lung cancer receiving moderately emetogenic chemotherapy (MEC). Methods: Patients with advanced or recurrent lung cancer who were treated with MEC regimens at the Department of Respiratory Medicine, Fukuoka University Hospital, were included and classified into the following groups: control group (treatment: 5-HT3 receptor antagonists + dexamethasone) and aprepitant group (treatment: 5-HT3 receptor antagonists + dexamethasone + aprepitant). The presence or absence of chemotherapy-induced nausea and vomiting (CINV) was evaluated according to the Common Terminology Criteria for Adverse Events (CTCAE) v4.0; patients with grade 1 or above were considered positive for CINV. Food intake per day, completion of planned chemotherapy, and progression-free survival (PFS) achieved by chemotherapy were investigated. Results: The complete suppression rate of nausea in the aprepitant group was significantly higher than that in the control group (p = 0.0043). Throughout the study, the food intake in the aprepitant group was greater than that in the control group, with the rate being significantly higher, in particular, on day 5 (p = 0.003). The completion rate of planned chemotherapy was also higher in the aprepitant group (p = 0.042). PFS did not differ significantly, but tended to be improved in the aprepitant group. Conclusions: The aprepitant group showed significantly higher complete suppression of nausea, food intake on day 5, and completion of planned chemotherapy than the control group.

• Journal of Internet Computing and Services
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• v.20 no.5
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• pp.113-119
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• 2019

The key features of 5G mobile communications recently commercialized can be represented by High Data Rate, Connection Density and Low Latency, of which the features most distinct from the existing 4G will be low Latency, which will be the foundation for various new service offerings. AR and self-driving technologies are being considered as services that utilize these features, and 5G Network Latency is also being discussed in related standards. However, it is true that the discussion of E2E Latency from a service perspective is much lacking. The final goal to achieve low Latency at 5G is to achieve 1ms of air interface based on RTD, which can be done through Ultra-reliable Low Latency Communications (URLLC) through Rel-16 in early 20 years, and further network parity through Mobile Edge Computing (MEC) is also being studied. In addition to 5G network-related factors, the overall 5G E2E Latency also includes link/equipment Latency on the path between the 5G network and the IDC server for service delivery, and the Processing Latency for service processing within the mobile app and server. Meanwhile, it is also necessary to study detailed service requirements by separating Latency for initial setup of service and Latency for continuous service. In this paper, the following three factors were reviewed for initial setup of service. First, the experiment and analysis presented the impact on Latency on the Latency in the case of 1 Data Lake Setup, 2 CRDX On/Off for efficient power, and finally 3H/O on Latency. Through this, we expect Low Latency to contribute to the service requirements and planning associated with Latency in the initial setup of the required services.

• Corrosion Science and Technology
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• v.22 no.5
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• pp.341-350
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• 2023

In the present study, effects of a thin Zn-flash coating on hydrogen evolution, infusion, and embrittlement of advanced high strength steel during electro-galvanizing were examined. The electrochemical permeation technique in conjunction with impedance spectroscopy was employed under applied cathodic polarization. Moreover, a slow-strain rate test was conducted to evaluate loss of elongation (i.e., indicative of hydrogen embrittlement (HE)) and examine fracture surfaces. Results showed that the presence of a thin Zn-flash coating, even when it was not distributed uniformly, reduced hydrogen evolution rate and substantially impeded infusion of hydrogen into the steel substrate. This was primarily due to a hydrogen overvoltage on Zn coating and trapping of hydrogen at the interface of Zn coating/flash coating/steel substrate. Consequently, the sample with flash coating had a smaller HE index than the sample without flash coating. These results suggest that a thin Zn-flash coating could be an effective technical strategy for mitigating HE in advanced high-strength steels.

• Korean Journal of Veterinary Research
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• v.48 no.1
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• pp.75-81
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• 2008

The rapid evolution of antibiotic resistance in Staphylococcus (S.) aureus is of considerable concern. Methicillin-resistant S. aureus (MRSA) strains are especially one of the greatest public concerns since the treatment of infections is more difficult when encountering resistance. In this study, we conducted a nationwide survey on the antimicrobial resistance of S. aureus isolated from raw meat samples collected from 16 countries, including Korea, and investigated the prevalence of MRSA as a possible source of human infection. Of 1,984 meat samples, S. aureus was isolated from 218 (11.0%) samples consisting of 23 (12.1%) from domestic meat and 195 (10.9%) from imported meat. The isolation rates of poultry meat, pork and beef were 12.8%, 7.0% and 10.0%, respectively. With regard to imported meat, the incidence varied from 4.8% to 16.6% from 13 countries, with the exception of Austria and Poland. In a resistance test to 20 antimicrobial agents, one hundred and eighty-four isolates (84.4%) were resistant to one or more antimicrobial agents tested. Especially, 17 (7.8%), 124 (56.9%) and 28 (12.8%) isolates showed a resistance to 3, 2 and 1 drugs, respectively. One isolate originating from domestic beef was resistant to 7 drugs. Another isolate originating from imported poultry meat showed resistance to oxacillin and methicillin by the disk diffusion test and minimal inhibition concentration methods, but showed negative for detection of the mecA gene.

• Journal of Korean Physical Therapy Science
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• v.3 no.1
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• pp.843-853
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• 1996

The purpose of this study was to determine whether extension exercise is effective in reducing low back pain. Nine patients with low back pain were randomly assigened to one of two groups-one was an experimental group in which the patient were treated with extension exercise(McKenzie method) and conservative therapy. The other was a control group in which the patients were treated with conservative therapy only. Treatment was performed for a period of ten days during Which we examed each patient three times: the first exam was done at the begining of treatment, the second after fives days, and the third after ten days. We used 'The Oswestry low back pain disability questionnaire'(r=.99) as the examination tool. The results were as follows: 1. Both experimental and control groups showed nonsignificant differences before and after treatment, and the between group difference was also non-significant(P>.05). 2. There was no effective reduction of low back pain by MecKenzie's extension exercise(p>.05). We admit that our study protocol had several shortcomings. If they had been accounted for, the result might have been different. Further study should be done with a better experimental design, a larger sample, and a longer experimental duration.

• Journal of Internet Computing and Services
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• v.22 no.6
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• pp.1-8
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• 2021

With the rapid growth of intelligent devices and communication technologies, 5G network environment has become more heterogeneous and complex in terms of service management and orchestration. 5G architecture requires supportive technologies to handle the existing challenges for improving the Quality of Service (QoS) and the Quality of Experience (QoE) performances. Among many challenges, traffic steering is one of the key elements which requires critically developing an optimal solution for smart guidance, control, and reliable system. Mobile edge computing (MEC), software-defined networking (SDN), network functions virtualization (NFV), and deep learning (DL) play essential roles to complementary develop a flexible computation and extensible flow rules management in this potential aspect. In this proposed system, an accurate flow recommendation, a centralized control, and a reliable distributed connectivity based on the inspection of packet condition are provided. With the system deployment, the packet is classified separately and recommended to request from the optimal destination with matched preferences and conditions. To evaluate the proposed scheme outperformance, a network simulator software was used to conduct and capture the end-to-end QoS performance metrics. SDN flow rules installation was experimented to illustrate the post control function corresponding to DL-based output. The intelligent steering for network communication traffic is cooperatively configured in SDN controller and NFV-orchestrator to lead a variety of beneficial factors for improving massive real-time Internet of Things (IoT) performance.

• Journal of Korean Academy of Nursing
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• v.37 no.6
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• pp.976-985
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• 2007

Purpose: The aim of this study was to identify the present situation of hospital infection and route of infection by clarifying the transmission aspect of methicillin-resistant Staphylococcus aureus(MRSA) in a Neurosurgical Intensive Care Unit by analysing genotype. Methods: MRSA was cultured from twenty five patients with a tracheostomy, twenty five health care workers, and environments in the Neurosurgical Intensive Care Unit of one hospital in D city. Data was collected from December 21, 2004 to November 5, 2005. MRSA isolates representing each genotype were analyzed by spaA typing and a multiplex PCR method capable of identifying the structural type of the staphylococcal cassette chromosome mec(SCCmec) carried by the bacteria. Results: As the same genotype and gene sequence were found among health care workers, patients, and environments, it was assumed that there was cross transmission among them. Conclusion: This study suggests that first, as the hospital infection by MRSA between health care workers and patients in the Neurosurgical Intensive Care Unit was due to result of cross transmission and the relevance of transmission between them was verified, it is necessary to take preventive measures and conduct education. Secondly, development of nursing interventions and study of infection are needed. Thirdly, consistent investment in prevention against hospital infections and environmental renovation is needed.