• Annals of Laboratory Medicine
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• 제38권6호
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• pp.518-523
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• 2018

Background: Lipemia, a significant source of analytical errors in clinical laboratory settings, should be removed prior to measuring biochemical parameters. We investigated whether lipemia in serum/plasma samples can be removed using a method that is easier and more practicable than ultracentrifugation, the current reference method. Methods: Seven hospital laboratories in Spain participated in this study. We first compared the effectiveness of ultracentrifugation ($108,200{\times}g$) and high-speed centrifugation ($10,000{\times}g$ for 15 minutes) in removing lipemia. Second, we compared high-speed centrifugation with two liquid-liquid extraction methods-LipoClear (StatSpin, Norwood, USA), and 1,1,2-trichlorotrifluoroethane (Merck, Darmstadt, Germany). We assessed 14 biochemical parameters: serum/plasma concentrations of sodium ion, potassium ion, chloride ion, glucose, total protein, albumin, creatinine, urea, alkaline phosphatase, gamma-glutamyl transferase, alanine aminotransferase, aspartate-aminotransferase, calcium, and bilirubin. We analyzed whether the differences between lipemia removal methods exceeded the limit for clinically significant interference (LCSI). Results: When ultracentrifugation and high-speed centrifugation were compared, no parameter had a difference that exceeded the LCSI. When high-speed centrifugation was compared with the two liquid-liquid extraction methods, we found differences exceeding the LCSI in protein, calcium, and aspartate aminotransferase in the comparison with 1,1,2-trichlorotrifluoroethane, and in protein, albumin, and calcium in the comparison with LipoClear. Differences in other parameters did not exceed the LCSI. Conclusions: High-speed centrifugation ($10,000{\times}g$ for 15 minutes) can be used instead of ultracentrifugation to remove lipemia in serum/plasma samples. LipoClear and 1,1,2-trichlorotrifluoroethane are unsuitable as they interfere with the measurement of certain parameters.

• Journal of Multimedia Information System
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• 제9권2호
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• pp.145-154
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• 2022

The authors are making a prototype flexible board of a radio-frequency transmitter for measuring an electromyogram (EMG) of a flying moth and plan to apply for an experimental station license from the Ministry of Internal Affairs and Communications of Japan in the summer of 2022. The goal is to create a continuous low-dose exposure standard that incorporates scientific and physiological functional assessments to replace the current standard based on lethal dose 50. This paper describes the technical evaluation of the hardware. The signal of a bipolar EMG electrode is amplified by an operational amplifier. This potential is added to a voltage-controlled crystal oscillator (27 MHz, bandwidth: 4 kHz), frequency-converted, and transmitted from an antenna about 10 cm long (diameter: 0.03 mm). The power source is a 1.55-V wristwatch battery that has a total weight of about 0.3 g (one dry battery and analog circuit) and an expected operating time of 20 minutes. The output power is -7 dBm and the effective isotropic radiated power is -40 dBm. The signal is received by a dual-whip antenna (2.15 dBi) at a distance of about 100 m from the moth. The link margin of the communication circuit is above 30 dB within 100 m. The concepts of this hardware and the measurement data are presented in this paper. This will be the first biological data transmission from a moth with an official license. In future, this telemetry system will improve the detection of physiological abnormalities of moths.

• Journal of Preventive Medicine and Public Health
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• 제55권3호
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• pp.253-262
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• 2022

We aimed to review the current data composition of the Korean Tuberculosis and Post-Tuberculosis Cohort, which was constructed by linking the Korean Tuberculosis Surveillance System (KNTSS; established and operated by the Korean Disease Control and Prevention Agency since 2000) and the National Health Information Database (NHID; established by the National Health Insurance Service in 2012). The following data were linked: KNTSS data pertaining to patients diagnosed with tuberculosis between 2011 and 2018, NHID data of patients with a history of tuberculosis and related diseases between 2006 and 2018, and data (obtained from the Statistics Korea database) on causes of death. Data from 300 117 tuberculosis patients (177 206 men and 122 911 women) were linked. The rate of treatment success for new cases was highest in 2015 (86.7%), with a gradual decrease thereafter. The treatment success rate for previously treated cases showed an increasing trend until 2014 (79.0%) and decreased thereafter. In total, 53 906 deaths were confirmed among tuberculosis patients included in the cohort. The Korean Tuberculosis and Post-Tuberculosis Cohort can be used to analyze different measurement variables in an integrated manner depending on the data source. Therefore, these cohort data can be used in future epidemiological studies and research on policy-effect analysis, treatment outcome analysis, and health-related behaviors such as treatment discontinuation.

• 대한전자공학회논문지TC
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• 제43권10호
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• pp.90-97
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• 2006

본 논문에서는 cascode 구조에 shunt peaking 기술을 접목시킨 밀리미터파 광대역 amplifier를 설계 및 제작하였다. 밀리미터파 광대역 cascode amplifier의 설계 및 제작을 위해서 $0.1{\mu}m\;{\Gamma}-gate$ GaAs PHEMT와 CPW 및 passive library를 개발하였다. 제작된 PHEMT는 최대 전달 컨덕턴스는 346.3 mS/mm, 전류이득 차단 주파수 ($f_T$)는 113 GHz, 그리고 최대공진 주파수($f_{max}$)는 180 GHz의 특성을 갖고 있다. 설계된 cascode amplifier는 회로의 발진을 막기 위해서 저항과 캐패시터를 common-rate 소자의 드레인에 병렬로 연결하였다. 대역폭의 확장 및 gain의 평탄화를 위해 바이어스 단들에 short stub 및 common-source 소자와 common-gate 소자 사이에 보상 전송선로를 삽입하고 최적화하였으며, 입출력 단은 광대역 특성을 갖는 정합회로로 설계하였다. 제작된 cascode amplifier의 측정결과, cascode 구조에 shunt peaking 기술을 접목시킴으로써 대역폭을 확장 및 gain을 평탄화 시킬 수 있다는 것을 확인하였다. 3 dB 대역폭은 34.5 GHz ($19{\sim}53.5GHz$)로 광대역 특성을 얻었으며, 3 dB대역 내에서 평균 6.5 dB의 $S_{21}$ 이득 특성을 나타내었다.

• 전기화학회지
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• 제11권1호
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• pp.42-46
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• 2008

연료전지는 수소를 직접 사용하는 것이 가장 효율이 높지만 가정이나 사무실에서는 수소 저장탱크를 사용하기보다는 도시가스(메탄가스)를 연료 source로 하여 수소를 생산하는 것이 유리하다. 연료전지에 사용하는 수소는 천연가스나 바이오가스, 탄화수소계열의 연료를 개질하여 생산하며 개질반응과정에서 필연적으로 여러 성분의 불순물이 포함되어 있다. CO, $CO_2$, $H_2S$, $NH_3$, $CH_4$등의 불순물이 포함된 수소연료가 PEM fuel cell에 공급되면 연료전지 성능에 영향을 준다고 보고되어 있다. 이러한 영향에는 전극 촉매의 피독에 의한 kinetic losses, 전해질막과 촉매이온층의 양이온 전도성 감소에 의한 ohmic losses 그리고 촉매층의 구조나 소수성 감소에 의한 mass transport losses가 있다. 개질기에서 생산된 수소연료는 약 73%의 $H_2$와 20% 이하의 $CO_2$, 5.8% 이하의 $N_2$, 2% 이하의 $CH_4$, 10ppm 이하의 CO로 최종 공급된다. 본 연구에서는 연료 중에 $CO_2$가 고분자전해질 연료전지 anode측 성능에 미치는 영향을 조사하였다. 실험은 연료전지에 공급되는 연료중에 $CO_2$농도를 10%, 20%, 30%로 전류와 전압의 성능곡선과 장시간(10시간)실험 그리고 임피던스를 측정하였다. 또한 가스크로마토그래피를 이용하여 순수한 수소와 $CO_2$가 함유된 수소의 혼합을 통해 나온 연료전지 inlet에서의 불순물의 농도를 검증하였다.

• 한국구조물진단유지관리공학회 논문집
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• 제27권6호
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• pp.30-38
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• 2023

안전점검 대상 노후 건축물이 증가함에 따라 안전관리 주체인 지정기관 및 관리주체의 부담이 증가하고 있다. 이에 안전점검 대상 건축물 선정에 있어 적절한 안전전검 기준과 그에 따르는 적절한 기술은 필수적이다. 현행 노후 건축물 대상 안전점검 수행 기준은 마감재로 인해 구조 부재 균열 등의 손상 확인이 어려울 경우 낮은 점수를 부여하고 있다. 이는 구조물의 실체 안전상태와 관계없이 평가 결과가 과소평가되어 안전점검 대상 노후화 건축물을 증가시키는 원인이다. 이에 본 연구에서는 마감재 내부의 균열 탐지를 위해 비파괴·비접촉 검사인 열화상 기법을 제안하였다. 열화상 카메라를 이용한 마감재 내부 균열 관측을 위해 콘크리트 시편을 제작하였으며, 콘크리트 표면 및 균열부에 열원을 가진하여 열화상 데이터를 계측하였다. 계측 결과, 너비 0.3mm, 0.5mm, 0.7mm의 마감재 내부 균열 관측이 가능함을 확인하였으나, 표면 박리, 도배지 들뜸으로 인한 불균일한 온도 분포로 인해 균열 판단이 어렵다. 이에 열화상 데이터의 진폭 및 위상 차이를 도출하여 데이터 분석을 수행한 결과, 0.5mm, 0.7mm 균열에 대해 선명한 균열 계측이 가능하였다. 본 연구를 토대로 추후 마감재 내부 균열 손상 진단에 있어 빅 데이터 기반 딥러닝을 이용한 기술개발을 통해 현장적용 및 분석의 효율성을 증대시키고자 한다.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2003년도 제27회 추계학술대회
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• pp.45-45
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• 2003

The aim of this study was the characterization and performance validation of new prototype avalanche photodiode (APD) arrays for positron emission tomography (PET). Two different APD array prototypes (noted A and B) developed by Radiation Monitoring Device (RMD) have been investigated. Principal characteristics of the two APD array were measured and compared. In order to characterize and evaluate the APD performance, capacitance, doping concentration, quantum efficiency, gain and dark current were measured. The doping concentration that shows the impurity distribution within an APD pixel as a function of depth was derived from the relationship between capacitance and bias voltage. Quantum efficiency was measured using a mercury vapor light source and a monochromator used to select a wavelength within the range of 300 to 700 nm. Quantum efficiency measurements were done at 500 V, for which the APD gain is equal to one. For the gain measurements, a pencil beam with 450 nm in wavelength was illuminating the center of each pixel. The APD dark currents were measured as a function of gain and bias. A linear fitting method was used to determine the value of surface and bulk leakage currents. Mean quantum efficiencies measured at 400 and 450 nm were 0.41 and 0.54, for array A, and 0.50 and 0.65 for array B. Mean gain at a bias voltage of 1700 V, was 617.6 for array A and 515.7 for type B. The values based on linear fitting were 0.08${\pm}$0.02 nA 38.40${\pm}$6.26 nA, 0.08${\pm}$0.0l nA 36.87${\pm}$5.19 nA, and 0.05${\pm}$0.00 nA, 21.80${\pm}$1.30 nA in bulk surface leakage current for array A and B respectively. Results of characterization demonstrate the importance of performance measurement validating the capability of APD array as the detector for PET imaging.

• 한국대기환경학회지
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• 제33권3호
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• pp.205-216
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• 2017

Carbonaceous aerosols such as the equivalent black carbon (eBC), the elemental carbon (EC) and the organic carbon (OC) were monitored at the Seoul Olympic Park site ($37.521^{\circ}N$, $127.124^{\circ}E$) during the KORUS-AQ 2016 campaign using a Multi Angle Absorption Photometer (MAAP) and an OCEC Analyzer. Averaged mass concentrations of eBC, EC and OC were presented as $2.46{\pm}1.52{\mu}g/m^3$, $1.01{\pm}0.60{\mu}g/m^3$ and $4.85{\pm}2.60{\mu}g/m^3$, respectively. OC/EC ratio and mass absorption cross-section (MAC) of light absorbing aerosols were calculated as 2.32 and $14.8m^2/g$, respectively. Diesel OC concentrations were estimated from a source profile of diesel vehicles as well. eBC mass concentrations measured from May $26^{th}$ to May $27^{th}$, 2016 showed 40% higher than averaged eBC mass concentrations during campaign period. $PM_{2.5}$ concentrations measured in this period were also higher than average $PM_{2.5}$ concentrations. High eBC concentrations were observed from May $29^{th}$ to May $31^{st}$, 2016 and from June $9^{th}$ to June $11^{th}$, 2016, possibly due to morning rush hour and the effect of temperature inversion at night. Diurnal variations of eBC, EC and Diesel OC showed a typical pattern of metropolitan area. In the weekend, however, diurnal variations of eBC, EC and Diesel OC mass concentrations were different from those measured in the weekday. It is expected that this study can help to understand the relationship between carbonaceous aerosols in a metropolitan area.

• 한국환경과학회지
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• 제18권4호
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• pp.389-400
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• 2009

In this research, we measured the number of lanes, distance, disposition of apartment that are affecting the road traffic noise to evaluate the current condition of G city's road traffic noise. We decide on a basis regarding an apartment price formation factor, and the apartment current price and the results that compared. To have a point scale, we set the maximum road traffic noise at a 8 lane road for 5 points, give 4 points for a 6 lane road, which has a $2.1{\sim}2.5\;dB(A)$ difference compared to a 8 lane road, give 3 points for a 4 lane road, which has a $5.2{\sim}5.5\;dB(A)$ difference compared to a 8 lane road, and set 2 points for a 2 lane road and lower. If we set the standard floor plan as horizontal and a living room facing the roadside, the horizontal and living room facing the opposite side of the road is 1 point because it differs by 14.1 dB(A), and the vertical is 3 points since the difference is 5.3 dB(A). If we make grades by the distance, making standard the fifth floor with little soundproof effect from apartment to road, we observe a measurement below 2.9 dB(A) at a distance of less than 10 m and 5 dB(A), decreased at a distance of 20 m. Therefore, 4 points were given for less than 10m, 3 points for $10{\sim}20\;m$, 2 points for more than 20 m as we can apply the effect of a decay distance of line sound source and the decrease in noise effects of more than 6 dB(A), 1 point for more than 40m, and 0 points for more that 80 m since it is negligible. 28 apartments got 0 points because there is no effect of road traffic noise from other apartments, and 50 apartments where only the road at one side effect them got $5{\sim}10$ points. 4 apartments (17-2, 6-3, 10-4, 3-3) received over 20 points. 15 cases showed a difference between developer price and resale price, and 11 cases (73%) among them showed the same trend (price increases with a low road traffic noise restriction factor point) with the point of road traffic noise restriction factor. 4 cases demonstrated the opposite trend, showing price increases with a high restriction factor point. Among the 4 cases, case numbers 2,6 and 9 appear to be more affected by the location factor (business district) than the road traffic noise restriction factor, and case number 1 appears to be affected by the building factor (openness and direction).

• 대한전자공학회논문지TC
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• 제44권7호통권361호
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• pp.41-46
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• 2007

본 논문은 두 개의 공통 게이트 증폭단을 사용한 캐스코형 CMOS 저잡음 증폭기의 후치 선형화 기법을 제안한다. 제안된 기법은 두 개의 공통 게이트 FET 단을 사용하며, 한 FET는 공통 소스단에서 전달된 전류 성분 중 선형 전류 성분만을 부하에 전달하고, 다른 한 단은 3차 혼변조 전류를 흡수하도록 동작한다. 선형 전류 성분과 혼변조 전류 성분을 선택적으로 분류하기 위해 $0.18{\mu}m$ CMOS 공정에서 제공되는 후막 (thick oxide) FET를 혼변조 전류 흡수용 FET로, 박막 (thin oxide) FET를 선형 전류 버퍼로 사용하였다. 제안된 방법을 검증하기 위해 $0.18{\mu}m$ CMOS 공정을 이용하여 2.14GHz에서 동작하는 저잡음 증폭기를 설계하였다. 제작된 차동 증폭기는 1.8V 전원에서 12.4mA를 소모하며, 측정 결과로 11 dBm IIP3, 15.5 dB 전력이득, 그리고 2.85 dB 잡음지수를 특성을 얻었다. 이는 후치 선형화가 없는 회로에 비해 7.5dB의 $IIP_{3}$ 개선된 결과이다.