• Journal of Korean Neurosurgical Society
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• 제47권5호
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• pp.345-351
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• 2010

Objective : In this study, the Mindfulness Based Stress Reduction (MBSR) program was applied to patients presenting with depression and anxiety after surgery from spontaneous subarachnoid hemorrhage (SAH) and the effects were assessed. Methods : The subjects were patients admitted for cerebral aneurysm rupture and treated by means of surgery from March to December, 2007. More than 6 months had passed after surgery, without any special lesions showing up on computed tomography (CT), and the Glasgow outcome scale (GOS) was 5 points. Among patients with anxiety and depression symptoms, 11 patients completed the program. The MBSR program was conducted once a week, 2.5 hours each, for 8 weeks. The evaluation criteria were : 1) the Beck Depression Inventory (BDI): it measures the type and level of depression, 2) the State-Trait Anxiety Inventory : the anxiety state of normal adults without mental disorder, and 3) Heart Rate Variability (HRV) : the influence of the autonomous nervous system on the sinoarterial node varies continuously in response to the change of the internal/external environment. Results : The BDI value was decreased from 18.5 ${\pm}$ 10.9 to 9.5 ${\pm}$ 7.1 (p = 0.013) : it was statistically significant, and the depression level of patients was lowered. The state anxiety was decreased from 51.3 ${\pm}$ 13.9 to 42.3 ${\pm}$ 15.2; the trait anxiety was reduced from 50.9 ${\pm}$ 12.3 to 41.3 ${\pm}$ 12.8, and a borderline significant difference was shown (p = 0.091, p = 0.056). In other words, after the treatment, although it was not statistically significant, a decreased tendency in anxiety was shown. In the HRV measurement, standard deviation normal to normal (SDNN), square root of the square root of the mean sum of squared differences between adjacent normal to normal intervals (RMSSD), and total power (TP) showed significant increase, Physical Stress Index (PSI) showed a significant reduction, and thus an improvement in the homeostatic control mechanism of the autonomic nervous system was ween. Conclusion : The MBSR program was applied to the patients showing anxiety and depression reaction after SAH treatment, and a reduction in depression symptoms and physiological reactions were observed. The application of the MBSR program may be considered as a new tool in improving the quality of life for patients after surgery.

• 대한지역사회영양학회지
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• 제7권4호
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• pp.506-515
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• 2002

This study examined the state of health and weight maintenance according to the body mass index (BMI) , and explored demographic variables, diet variables, the degree of stress etc. The results presented were based on data collected from 428 women who are mothers of the middle school children in Jeongeup city. Using SPSS WIN (Ver 9.0) , the frequency, percentage, mean, standard deviation, chi-square, ANOVA, and correlation analysis were provided. The mean of BMI for the subjects was 22.6, the ratio of obese women (BMI $\geq$ 25) was 22.9%. The frequency of the reported circulation or respiratory related diseases was greater in the obese group compared to the normal weight ($20 \leq BMI \leq 25$) or the lean (BMI < 20) groups. The obese group had less awareness of obesity. Those who regard themselves obese had lower rates of satisfaction with their body shape and higher rates of interest in weight control. Approximately 65% of the subjects attempted weight reduction more than once. Subjects who were obese had the most undesirable dietary behavior. In particular, this group had the higher rates of rushed meals, overeating, meals while watching TV or newspapers, and snacking, and eating out. In analyzing the correlation of variables influencing obesity, there were positive correlations between obesity and overeating, obesity and the degree of stress. Correlations between obesity and satisfaction for life found to be negative. Moreover, stress had a positive correlation with obesity and overeating, and showed negative correlation with eating behavior. Consequently, stress seemed to induce undesirable eating behaviors and increase obesity. Of the demographic background variables, subjects who were obese tended to be older, had lower levels of education, higher rates of employment, longer period of marriage, the higher number of children, preschool children or children preparing for highschool or college, lower satisfaction with children and household life.

• 대한지역사회영양학회지
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• 제4권4호
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• pp.561-567
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• 1999

This study was conducted to provide information about weight control behavior in adolescent females. To explain the behavior intention of dieting, conceptual framework based on "Social Support, Control and the Stress Process Model" and "Theory of Reasoned Action" was used. The survey was carried out by self-questionnaires with 463 female high school and college students in Daegu. Analysis of data was done using mean, correlation and multiple regression analysis with the SAS computer program. A society preoccupied with thinness gives a burden to women, and this burden may stress dissatisfaction with body image. Social perception of ideal body image except parents' perception, and salient others'perception, and salient others' expectation of subjects' body image except parents' expectation, were much thinner than normal figures in this study. The influencing factors for behavior intention of dieting of the subjects were perceived stress and attitude toward diet behavior, especially beliefs of behavioral outcome. Influencing factors related to perceived stress-that is dissatisfaction of body image-were current figure, social perception of body image, effect of mass communication and others' estimation of subjects' body image with self-comparison with others, in order.th others, in order.

• 대한핵의학회지
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• 제39권6호
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• pp.430-437
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• 2005

목적: 게이트 심근 관류 스펙트 결과의 정량적 평가를 위해 여러 프로그램들이 사용되고 있다. 하지만 프로그램별로 각각의 정상 범위의 설정 없이 외국의 자료만을 토대로 프로그램의 구분 없이 일률적으로 판독에 적용하고 있다. 이에 심혈관 질환의 가능성이 낮은 환자를 대상으로 본원에서 일반적으로 사용하고 있는 QGS와 4DM의 심기능 지표(EDV, ESV, EF)에 대한 정상 값을 구하였고, 두 프로그램간의 결과 치에 대한 상관관계도 조사하였다. 대상 및 방법: Pryor 등에 의해 만들어진 평가표에 근거하여 심혈관 질환의 가능성이 10% 미만인 남녀 77명을 대상으로 아데노신 부하법을 이용한 Tc-99m MIBI 게이트 심근 관류 스펙트를 실시하였다. EDV, ESV, EF의 결과 분석은 QGS와 4DM을 이용하였으며, 좌심실의 경계는 자동으로 설정하도록 하였다. 결과: QGS에서 부하기 좌심실의 평균 EDV, ESV, EF는 각각 $78.2{\pm}25.2ml,\;27.4{\pm}12.9ml,\;66.6{\pm}8.0%$ 이었고 휴식기의 결과치와 통계학적으로 큰 차이는 없었다(p>0.05). 4DM에서 부하기 좌심실의 평균 EDV, ESV, EF는 각각 $89.1{\pm}26.4ml,\;29.1{\pm}12.8ml,\;68.5{\pm}6.7%$ 이었다. 대체적으로 QGS와 마찬가지로 휴식기의 결과치와 큰 차이는 없었으나 EF의 경우에서 부하기와 휴식기에 통계학적인 차이가 있었고 (p<0.05) 휴식기의 EF가 약간 큰 값을 보였다(부하기 $68.5{\pm}6.7%$ vs 휴식기 $70.9{\pm}8.0%$). 두 프로그램에서 EDV, ESV, EF의 결과 값의 상관관계는 부하기에서 각각 0.95, 0.93, 0.71이었고 휴식기에서 각각 0.95, 0.90, 0.69으로 대체적으로 좋았으나 Bland-Altman분석에서 두 프로그램의 일치의 한계 값의 범위가 비교적 컸음을 볼 수 있었다. 결론: 이번 연구를 통하여 심혈관 질환의 가능성이 낮은 환자에서 QGS와 4DM 프로그램 각각의 EDV, ESV, EF의 정상 값을 구하였다. 두 프로그램의 상관관계는 높지만 두 프로그램의 결과 값을 혼용하여 사용할 수는 없을 것이다. 이를 이용하여 앞으로 판독에 유의한 참고 자료로써 사용될 수 있을 것으로 생각된다.

• 임상간호연구
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• 제27권2호
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• pp.121-129
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• 2021

Purpose: The purpose of this study was to investigate post-traumatic stress, job stress, fatigue, and social support of nurses in direct care for COVID-19 patients and to identify the factors affecting post-traumatic stress among the nurses. Methods: The participants were 150 nurses from three hospitals. Data were collected from September 11, 2020 to September 21, 2020. The data were analyzed with SPSS/WIN/25.0 program. Results: The mean score of post-traumatic stress was 22.27±15.49 (range 0~88). The percentage of high risk group of post-traumatic stress was 35.3%, risk group was 20.0%, normal group was 44.7%. Post-traumatic stress showed statistically significant differences according to quarantined experience (t=2.15, p=.033), and provision of COVID-19 manual (t=-2.40, p=.026). Post-traumatic stress was positively correlated with job stress (r=.48, p<.001), and fatigue (r=.58, p<.001), and it was negatively correlated with social support (r=-.22, p=.005). Job stress was positively correlated with fatigue (r=.74, p<.001), and it was negatively correlated with social support (r=-.17, p=.030). Fatigue and social support (r=-.17, p=.029) had a negative correlation. The results of regression analysis showed that the factors affecting post-traumatic stress included fatigue (β=.56, p<.001), provision of COVID-19 manual (β=-.24, p<.001), and quarantined experience (β=.18, p=.006) and that the total explanatory power was 42.0%. Conclusion: In this study, fatigue, provision of COVID-19 manual, and quarantined experience were found as influential factors of post-traumatic stress among nurses in direct care for COVID-19 patients. Therefore, development of the intervention for reducing the fatigue should consider to prevent post-traumatic stress in nurses. Also, provision of COVID-19 manual for nurses and psychological intervention program for nurses experienced quarantine are necessary.

• 대한임상검사과학회지
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• 제44권3호
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• pp.128-135
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• 2012

The kidney and cochlea have similar physiological characteristics, specifically the active transport of fluid and electrolytes, similar effects of aminoglycosides and some immunological factors. Several mitochondrial DNA (mtDNA) defects have been identified to be associated with hearing impairment either in syndromic or nonsyndromic forms. Dialysis patients had more oxidative stress than healthy subjects and this elevated oxidative stress leads to alterations of the mtDNA. To generate a more comprehensive analysis of the relationship between mitochondrial variation and hearing loss, two SNPs of 10609, 14668 position showed nominal levels of association with hearing loss. In our result, the mean PTA values in the ESRD patients were $28{\pm}13.9\;(mean{\pm}SD)dB$ and $51.0{\pm}23.2dB$ in low and high frequencies, which were significantly higher than those in the normal controls. 10609T>C and 14668C>T were significantly associated with hearing loss in the ESRD patients. In summary, our results suggest that the polymorphisms of the ND4L subunit gene might be association with ESRD patients and hearing loss.

• 대한약침학회지
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• 제22권2호
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• pp.83-89
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• 2019

Introduction: Oxidative stress (OS) during uncontrolled hyperglycemia has a pivotal role in pancreatic dysfunction. Our study aimed to demonstrate that crocin can potentiate anti-oxidant defense systems of pancreatic cells to improve oxidative stress. Methods: Male Wistar rats were divided randomly into four groups: a normal group, a normal-treated group, a diabetic group and a diabetic-treated group (n = 6 rats per group). Diabetes was induced by a single dose of streptozotocin (45 mg/kg/IV). The treated groups received crocin daily for 8 weeks (40 mg/kg/IP). At the end of the experiment, rats were sacrificed and pancreas tissue was obtained. Subsequently, the concentrations of malondialdehyde (MDA), nitrate and glutathione as well as the enzymatic activities of catalase and superoxide dismutase (SOD) were determined in all animals. Data were analyzed by two-way ANOVA with appropriate post hoc testing and a probability value of P < 0.05 was considered to represent a statistically significant difference in mean values. Results: Uncontrolled hyperglycemia weakened the anti-oxidant system by decreasing SOD and catalase enzyme activity in pancreatic tissues and induced OS by increasing the MDA content in diabetic non-treated animals. Crocin potentiated the anti-oxidant defense system by increasing the activity of both SOD and catalase, and improved OS by diminishing MDA production in pancreatic cells of rats contained in the diabetic-treated group. Conclusion: Based on our results, it is concluded that uncontrolled hyperglycemia can weaken the anti-oxidant defense system and cause the development of OS. Also, crocin can improve OS in pancreatic cells by potentiating the anti-oxidant defense system.

• Journal of Acupuncture Research
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• 제25권1호
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• pp.15-23
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• 2008

Objectives : The aim of our study was to demonstrate the clinical application of a diagnosis relating the 7-zone-diagnostic system and heart rate variability. Materials and Methods : Subjects were divided into two groups according to the factor AA form of the 7-zone-diagnostic system(VEGA-DFM722, VEGA, Germany). Subjects in group A showed a factor-AA red bar graph in which zone 2 was higher than the normal range, and zone 6 was lower than the normal range. Subjects in group B showed a factor-AA red bar graph in which zone 2 was lower than the normal range, and zone 6 was higher than the normal range. We investigated how to differentiate the index of heart-rate variability(HRV, LX-3202, LAXTHA, Korea) for each group. We did independent sample t-tests and evaluated the results of the HRV at the 5% significance level using SPSS 10.0 for Windows. Results : The differences of the MeanRR, MeanHRV, SDNN, complexity, HRV-index, RMSSD, SDSD, and pNN50 values between the groups was not significant. The differences of the Ln(TP), Ln(VLF), Ln(HF), LF/(LF+HF), LF/HF, norm LF, and norm HF values between the groups was also not significant. The differences were not significant, but generally the values of SDNN, complexity, RMSSD, SDSD, Ln(VLF), Ln(HF) and norm LF for group B were higher than those for group A, and the values of pNN50 and norm HF for group B were lower than those for group A. Conclusions : This study suggests that differences in the HRV values between the groups was not significant, but group B has a tendency to be healthier than group A because of stress. Accordingly, further study will be required.

• 대한핵의학회지
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• 제25권1호
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• pp.27-36
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• 1991

Thirty-one patients with coronary artery disease and twenty-sir normal subjects underwent $^{99m}Tc-GBPS$ before and after coronary vasodilatation was induced by dipyridamle 0.54 mg/kg given IV over 4 min. LVEF, ${\Delta}EF$ and regional wall motion by phase analysis were measured during rest and dipyridamole infusion. The results were as follows: 1) Mean LVEF of normal subjects was significantly higher than that of MI group (p=0.001), but similar to that of angina group during rest. Among MI group, mean LVEF of anterior MI group was significantly lower than that of inferior MI group during rest (p=0.024). 2) The normal subjects had a significaat increase in mean LVEF during dipyridamole infusion $(+12{\pm}3.8)$, while the CAD group had no increase $(+2{\pm}5.0)$ (p<0.001). If an increase of LVEF during stress is less than 5%, it suggests an abnormality. The sensitivity and specificity of LVEF changes after dipyridamole infusion were 81%, 96%, respectively. 3) With phase analysis, LV mean phase angle of normal subjects and CAD patients was $143{\pm}20.5^{\circ},\;132{\pm}20.6^{\circ}$ respectively, durign rest (p=0.049). But an ncrease of LV mean phase angle during dipyridamole infusion in these two groups was not significantly different. Dipyridamole infusion did not affect standard deviation and FWHM of phase angle. 4) Regional wall motion was abnormal in 5 patients (16%) during dipyridamole infusion. 5) Side effects with dipyridamole infusion include; headache, angina pain, chest discomfirt, nausea, weakness sense. In conclusion, dipyridamole GBPS might be useful in detection and follow up of CAD.

• 한국안전학회지
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• 제5권3호
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• pp.8-26
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• 1990

It is important to have exact information about the contact pressure distribution in the design of connected parts of machines and structures. In previous works, stress analyses on a two body contact problem have been carried out in large numbers. Besides, the measurement of contact stress is important to confirm the adequateness of the theoretical analysis, to verify appropriateness of Hertzian contact theory and to know the practical pressure distribution, but an excellent measuring method con't be found at present. Therefore, a quantitative measurement of contact pressure by means of ultrasonic waves using a normal probe and an angle has been proposed to measure the contact pressure distribution between two rough flat surfaces. At first, in a new proposed calibration method, the relation between mean contact pressure and sound pressure of reflected waves is obtained by using calibration blocks with various surface roughnesses made of the same material as the rectangular section beams And then, this experimental results are compared with the analytical ones, and the utility of this method is discussed.