• Title/Summary/Keyword: Mean Curve

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Analysis of SEER Adenosquamous Carcinoma Data to Identify Cause Specific Survival Predictors and Socioeconomic Disparities

  • Cheung, Rex
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.1
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    • pp.347-352
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    • 2016
  • Background: This study used receiver operating characteristic curve to analyze Surveillance, Epidemiology and End Results (SEER) adenosquamous carcinoma data to identify predictive models and potential disparities in outcome. Materials and Methods: This study analyzed socio-economic, staging and treatment factors available in the SEER database for adenosquamous carcinoma. For the risk modeling, each factor was fitted by a generalized linear model to predict the cause specific survival. An area under the receiver operating characteristic curve (ROC) was computed. Similar strata were combined to construct the most parsimonious models. Results: A total of 20,712 patients diagnosed from 1973 to 2009 were included in this study. The mean follow up time (S.D.) was 54.2 (78.4) months. Some 2/3 of the patients were female. The mean (S.D.) age was 63 (13.8) years. SEER stage was the most predictive factor of outcome (ROC area of 0.71). 13.9% of the patients were un-staged and had risk of cause specific death of 61.3% that was higher than the 45.3% risk for the regional disease and lower than the 70.3% for metastatic disease. Sex, site, radiotherapy, and surgery had ROC areas of about 0.55-0.65. Rural residence and race contributed to socioeconomic disparity for treatment outcome. Radiotherapy was underused even with localized and regional stages when the intent was curative. This under use was most pronounced in older patients. Conclusions: Anatomic stage was predictive and useful in treatment selection. Under-staging may have contributed to poor outcome.

Dental maturity of Saudi children: Role of ethnicity in age determination

  • Baghdadi, Ziad D.
    • Imaging Science in Dentistry
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    • v.43 no.4
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    • pp.267-272
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    • 2013
  • Purpose: Demirjian's dental maturity scores and curves have been widely used for human age determination. Several authors have reported considerable differences between the true and estimated age based on the Demirjian curves, which have been accounted for by ethnicity. The purpose of the current study was to assess the role of ethnicity-specific dental maturation curves in age estimation of Saudi children. Materials and Methods: A sample of 452 healthy Saudi children aged 4 to 14 years were aged based on the original French-Canadian Demirjian curves and several modified Demirjian curves specified for certain ethnic groups: Saudi, Kuwaiti, Polish, Dutch, Pakistani, and Belgian. One-way ANOVA and a post hoc Scheff$\acute{e}$'s test were used to assess the differences between chronological age and dental age estimated by the different curves (P<0.05). Results: The curves designed for Dutch, Polish, Saudi, and Belgian (5th percentile) populations had a significantly lower error in estimating age than the original French-Canadian and Belgian (50th percentile) curves. The optimal curve for males was the Saudi one, with a mean absolute difference between estimated age and chronological age of 8.6 months. For females, the optimal curve was the Polish one, with a mean absolute difference of 7.4 months. It was revealed that accurate age determination was not related to certain ethnicity-specific curves. Conclusion: We conclude that ethnicity might play a role in age determination, but not a principal one.

Strain energy-based fatigue life prediction under variable amplitude loadings

  • Zhu, Shun-Peng;Yue, Peng;Correia, Jose;Blason, Sergio;De Jesus, Abilio;Wang, Qingyuan
    • Structural Engineering and Mechanics
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    • v.66 no.2
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    • pp.151-160
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    • 2018
  • With the aim to evaluate the fatigue damage accumulation and predict the residual life of engineering components under variable amplitude loadings, this paper proposed a new strain energy-based damage accumulation model by considering both effects of mean stress and load interaction on fatigue life in a low cycle fatigue (LCF) regime. Moreover, an integrated procedure is elaborated for facilitating its application based on S-N curve and loading conditions. Eight experimental datasets of aluminum alloys and steels are utilized for model validation and comparison. Through comparing experimental results with model predictions by the proposed, Miner's rule, damaged stress model (DSM) and damaged energy model (DEM), results show that the proposed one provides more accurate predictions than others, which can be extended for further application under multi-level stress loadings.

Methodology for the Identification of Impaired Waters Using LDC for the Management of Total Maximum Daily Loads (오염부하지속곡선(LDC)을 이용한 수질오염총량관리 단위유역 목표수질 달성여부 평가방법)

  • Park, Jun Dae;Oh, Seung Young
    • Journal of Korean Society on Water Environment
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    • v.28 no.5
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    • pp.693-703
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    • 2012
  • Load Duration Curve(LDC) is a useful tool for analyzing water quality characteristics under various stream flow conditions. This study investigated the methods to identify impaired waterbodies in the assessment of water quality goal attainment by using LDC for the management of Total Maximum Daily Loads (TMDLs). Three methods were proposed. Non-typical regime exclusion method is a method to exclude water quality observations in the non-typical extreme flow conditions in order to minimize the influence of non-ordinary water quality. Flow regime weighted average method is a method to calculate weighted mean water quality instead of arithmetic mean in order to consider water characteristics properly on stream flow regime in addition to the effect of Non-typical regime exclusion method. Load exceeded interval comparison method is a method to compare the intervals between the attained and non-attained load duration periods on the LDC. The assessment of water quality goal attainment can be performed more reasonably and precisely considering water quality variations on stream flow conditions by applying these proposed methods.

A Study on the Income Inequality among the Fishing Communities in Korea (어촌계의 소득 격차와 변화에 관한 연구)

  • Ock, Young-Soo
    • The Journal of Fisheries Business Administration
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    • v.39 no.3
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    • pp.25-47
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    • 2008
  • The Fishing Communities (so-called Uchongae) in Korea was legally established in 1962. It has been gradually expanded by quantity, and we have total 1,969 communities in 2006. The major establishment purpose of Uchongae was put 2 functions. The first function is to make up the double industry structure in coastal region, and second function is to make economical condition for Uchongae. Nevertheless the Fishing Communities System in Korea was not successfully developed after first beginning. The Income gap have become heavily between fishing area and non - fishing area, including agricultural area. The income gap has been due to rapid industrialization and urbanization in Korea. And the income gap even have become heavily among Uchongaes. In this paper, It have been researched the degree of Income inequality among Uchongaes in Korea during 1986-2006. The income inequality degree was analyzed by Gini coefficient and Mean Log Deviation (MLD) using Lorenz Curve. According to analysis result, the Gini coefficient of Uchongaes in Korea has been about 2-times high from 0.0847 to 0.1770 during 20 years. And the MLD has been 5.4 times from 0.0125 to 0.0679 during same periods. This means to more wide the general Income Inequality among the Uchongaes in Korea. Especially, It means to more wide the gap of high ranking Uchongaes and low ranking Uchongaes that MLD index multiplier has been more high.

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Ultrasonographic evaluation of skin thickness in small breed dogs with hyperadrenocorticism

  • Heo, Seonghun;Hwang, Taesung;Lee, Hee Chun
    • Journal of Veterinary Science
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    • v.19 no.6
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    • pp.840-845
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    • 2018
  • The purpose of this study was to propose a standard for differentiation between normal dogs and patients with hyperadrenocorticism (HAC) by measuring skin thickness via ultrasonography in small breed dogs. Significant changes in skin thickness of patients treated with prednisolone (PDS) or patients with HAC treated with trilostane were evaluated. Skin thickness was retrospectively measured on three abdominal digital images obtained from small breed dogs weighing < 15 kg that underwent abdominal ultrasonography. Mean skin thickness of normal dogs was $1.03{\pm}0.25mm$ (mean ${\pm}$ SD). Both the HAC and PDS groups showed significantly thinner skin than that in the normal group. Seven of the 10 HAC patients treated with trilostane had increased skin thickness. The area under the curve value of 0.807 was based on the receiver operating characteristics (ROC) curve for differentiating normal dogs from HAC patients. Sensitivity was 76% and specificity was 73% when skin thickness was less than the 0.83 mm cutoff value. In conclusion, measurement of skin thickness in small breed dogs by using ultrasonography is likely to provide clinical information useful in differentiating HAC patients from normal dogs. However, exposure to PDS, trilostane, and other conditions may have a significant effect on skin thickness.

Mesh selectivity of gill nets for silver promfret, Pampus argenteus (병어(Pampus argenteus) 자망의 망목선택성)

  • Chang, Ho-Young;Cho, Bong-Kon;Park, Jong-Soo;Lee, Wang-Lae
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.43 no.3
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    • pp.169-175
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    • 2007
  • To examine the mesh selectivity and optimum mesh size of gill nets for silver promfret Pampus argenteus, the field experiments were carried out during June 27th to July 3rd, 2005 at the coastal area of Imja island. The experimental gill nets for silver promfret were used in two set, which one set was consisted of 12 sheets, and each set was connected alternatively four defferent sheets those were 141mm, 148mm, 155mm and 164mm in mesh size. The analysis of mesh selectivity curve was done by Kitahara's method. The total number of fishes caught by experimental fishing of gill nets for silver promfret was 1,409, and it was consisted of 1,022 silver promfrets(72.5%), 123 croakers(8.7%), 70 red tongue soles(5.0%), 67 blue crabs(4.8%), 22 red seabreams(1.6%), and 105 other fishes(7.4%). The number of fishes caught by the mesh size was 244 at mesh 141mm(mean 6.8/sheet), 261 at mesh 148mm(mean 7.3/sheet), 295 at mesh 155mm(mean 8.2/sheet) and 222 at mesh 164mm(mean 6.2/sheet). The body weight of fishes caught by the mesh size was 102.1kg at mesh 141mm(mean 2.8kg/sheet), 112.9kg at mesh 148mm(mean 3.1kg/sheet), 132.8kg at mesh 155mm(mean 3.7kg/sheet), and 100.4kg at mesh 164mm(mean 2.8kg/sheet). The value of maximum l/m on mesh selectivity curve and the value of l/m on the selection range of 50% was estimated at 1.91 and from 1.63 to 2.23, respectively. Therefore, the optimum mesh size of gill nets for silver promfret was estimated 135mm, and the total length at the selection range of 50% was from 220mm to 301mm. But, it will be useful to use the mesh size of gill nets which is about 10-15% larger than the estimated optimum mesh size of gill nets considering the number of fishes caught, body length and body weight etc.

Relationship between Maximum Stem Volume and Density during a Course of Self-thinning in a Cryptomeria japonica Plantation

  • Ogawa, Kazuharu;Hagihara, Akio
    • The Korean Journal of Ecology
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    • v.27 no.1
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    • pp.27-33
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    • 2004
  • Cryptomeria japonica plantation was monitored every year during 15 years from 1983 to 1997 for stem diameter and volume. The reciprocal equation, 1/Y = A + B/N, was applied to the relationship between cumulative volume Y and cumulative number N from the largest tree in the stand each year. The parameters A and B, which means respectively the reciprocal of an asymptotic value of total stand stem volume and the reciprocal of the maximum stem volume, are related by a power function. The power functional relationship between A and B derived a linear relationship of B-points ( $N_{B}$, $V_{B}$; $N_{B}$ = B/A, $Y_{B}$ = 1/2A) of each Y-N curve on log-log coordinates. The gradient of B-point line was so steep that the Y-N curve moved parallel upward year by year. The time trajectory of mean stem volume (W) and density ($\rho$) provided evidence in favor of the 3/2 power law of self-thinning, because the gradient of W - $\rho$ trajectory on log-log coordinates approximated to -3/2 at the final stage of stand development. On the basis of the results of Y-N curves and W - $\rho$ trajectory, the time trajectory of maximum stem volume $W_{max obs}$ and $\rho$ was derived theoretically. The gradient of $W_{max obs}$ - $\rho$ trajectory on log-log coordinates is calculated to be -0.6105 at the final stage. The gradient of $W_{max obs}$ - $\rho$ trajectory was steeper than that of W - $\rho$ trajectory at the early stage, while the former is gentler than the latter at the later stage.stage.e.age.e.

Balloon Kyphoplasty for the Treatment of Vertebral Compression Fractures (척추 압박골절 환자에서의 풍선 척추체 복원술의 치료 효과)

  • Han, Kyung Ream;Kim, Chan;Yang, Jong Yoon;Han, Seung Tak;Kim, Yeui Seok
    • The Korean Journal of Pain
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    • v.19 no.1
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    • pp.56-62
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    • 2006
  • Background: Balloon kyphoplasty is the new technique that helps to decrease the pain and improve mobility as well as restore the vertebral body height and kyphotic curve in fractured vertebrae. We evaluated the outcome of balloon kyphoplasty in the reduction of vertebral body height, kyphotic curve and clinical improvement in the patients with painful vertebral compression fractures. Methods: From July 2002 to February 2005, 84 levels of vertebral compression fractures in 66 patients were treated with balloon kyphoplasty. The assessment criteria were the changes over time in visual analogue scale (VAS) and mobility score. We evaluated the vertebral body height and kyphotic curve at preoperative 1 day and postoperative 1 day. Results: Procedures were performed in 66 patients with a total of 84 affected vertebral bodies. The anterior wall height was restored in 74 / 84 (88%) levels with a mean increment of 2.9 mm, and the mid-vertebral body height was restored in 79 / 84 (94%) levels with a mean increment of 4.2 mm. Kyphosis correction was achieved in 60 / 84 (71.4%) from 10.1 degrees to 7.5 degrees. Pain intensity reduced by 60% in one day after operation and by 75-85% in later time. Mobility scores of all patients were improved immediately after the procedure. Cement leakage occurred in 3 levels but there was no clinical problem. Conclusions: Kyphoplasty is an efficient and safe treatment of painful vertebral compression fracture in pain relief, mobility improvement, and reduction of deformity.

Estimating Maintenance Cost of RAPCON at Air Force Base (비행기지 RAPCON 유지보수비용 추정)

  • Bang, Jang-Kyu;Lee, Gun-Young
    • Journal of Advanced Navigation Technology
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    • v.20 no.6
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    • pp.511-518
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    • 2016
  • RAPCON non only controls landing/take-off procedures but also approaching air traffics within 60-70 NM range of air force base. This paper, first of all, tries to research the failure rate per operation hours, mean time between failure (MTBF) of RAPCON according to six blocks such as interrogator, receiver, power unit, display unit, data process unit and antenna. In addition, this paper estimates the maintenance cost over next 10 months based on 50 monthly maintenance cost data. Considering the maintenance cost data from RAPCON which has been used over designed service life span, it is no doubt the forecasted data proved the monthly cost would go up incrementally during the rest of economic life of the facility. Such research result is also proven to be the same with the result of bathtub curve data during operating life.