• Title/Summary/Keyword: Mathematical Human Model

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The Within-Host Population Dynamics of Normal Flora in the Presence of an Invading Pathogen and Antibiotic Treatments

  • Kim, Jung-Mo;Lee, Dong-Hwan;Song, Yoon-Seok;Kang, Seong-Woo;Kim, Seung-Wook
    • Journal of Microbiology and Biotechnology
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    • v.17 no.1
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    • pp.146-153
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    • 2007
  • A mathematical competition model between normal flora and an invading pathogen was devised to allow analysis of bacterial infections in a host. The normal flora includes the various microorganisms that live on or within the host and act as a primary human immune system. Despite the important role of the normal flora, no mathematical study has been undertaken on models of the interaction between it and invading pathogens against a background of antibiotic treatment. To quantify key elements of bacterial behavior in a host, pairs of nonlinear differential equations were used to describe three categories of human health conditions, namely, healthy, latent infection, and active infection. In addition, a cutoff value was proposed to represent the minimum population level required for survival. The recovery of normal flora after antibiotic treatment was also included in the simulation because of its relation to human health recovery. The significance of each simulation parameter for the bacterial growth model was investigated. The devised simulation showed that bacterial proliferation rate, carrying capacity, initial population levels, and competition intensity have a significant effect on bacterial behavior. Consequently, a model was established to describe competition between normal flora and an infiltrating pathogen. Unlike other population models, the recovery process described by the devised model can describe the human health recovery mechanism.

A Simulation Model of the ACL Function Using MADYMO (마디모를 이용한 전방십자인대 기능 시뮬레이션 모델)

  • Park, Jung-Hong;Son, Kwon
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.30 no.11 s.254
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    • pp.1408-1416
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    • 2006
  • A mathematical knee model was constructed using MADYMO. The purpose of this study is to present a more realistic model of the human knee to reproduce human knee motion. Knee ligaments were modeled as line elements and the surrounding muscles were considered as passive restraint elements. A calf-free-drop test was performed to validate the suggested model. A calf was dropped from the rest at about 65 degree flexed posture in the prone position. The motion data were recorded using four video cameras and then three dimensional data were acquired by Kwon3D motion analysis software. The results showed that general shapes of angular quantities were similar in both the experiment and computer simulation. Functional stability of the anterior cruciate ligament was explicitly revealed through this model.

Synchronization of Dynamical Happiness Model

  • Bae, Youngchul
    • International Journal of Fuzzy Logic and Intelligent Systems
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    • v.14 no.2
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    • pp.91-97
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    • 2014
  • Chaotic dynamics is an active research area in fields such as biology, physics, sociology, psychology, physiology, and engineering. Interest in chaos is also expanding to the social sciences, such as politics, economics, and societal events prediction. Most people pursue happiness, both spiritual and physical in many cases. However, happiness is not easy to define, because people differ in how they perceive it. Happiness can exist in mind and body. Therefore, we need to be happy in both simultaneously to achieve optimal happiness. To do this, we need to synchronize mind and body. In this paper, we propose a chaotic synchronization method in a mathematical model of happiness organized by a second-order ordinary differential equation with external force. This proposed mathematical happiness equation is similar to Duffing's equation, because it is derived from that equation. We introduce synchronization method from our mathematical happiness model by using the derived Duffing equation. To achieve chaotic synchronization between the human mind and body, we apply an idea of mind/body unity originating in Oriental philosophy. Of many chaotic synchronization methods, we use only coupled synchronization, because this method is closest to representing mind/body unity. Typically, coupled synchronization can be applied only to non-autonomous systems, such as a modified Duffing system. We represent the result of synchronization using a differential time series mind/body model.

A Mean of Structural equation modeling on AMOS Software (AMOS 소프트웨어에서 구현되는 구조방정식 모형과 의미)

  • Kim, Kyung-Tae
    • Proceedings of the Korean Association for Survey Research Conference
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    • 2007.11a
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    • pp.55-65
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    • 2007
  • In this research, it will be examined on mathematical model of AMOS software program that ues for Covariance Structure Analysis. if we have not understood to mathematical model of Covariance Structure, we fail to understand Structural equation modeling. Similarly If We were not understand to mathematical model of AMOS Software, we do not use Software adequately. Therefore we examine two sorts of Software that be designed for Structural equation modeling or Covariance Structure Analysis. In this research, We will focus on 8 assumption of Structural equation modeling and compare AMOS(Analysis of MOment Structure) program with LISREL(Linear Structure RELation) program. We found that A Program of AMOS Software have materialized with RAM(Reticular Action Model).

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Pallet speed control in a sintering plant using neural networks (신경회로망을 이용한 소결기 팰릿 속도 제어)

  • Jang, Min;Cho, Sung-Jun
    • Proceedings of the Korea Database Society Conference
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    • 1999.06a
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    • pp.261-270
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    • 1999
  • Sintering transforms powdered ore into lumped ore so that the latter can be used in a blast furnace. The powdered ore combined with coke and other materials is loaded into a container and moved along by a pallet while the ignited coke bums. The speed by which the pallet moves determines how much sintering takes place. Since the process is complicated and lacks an accurate mathematical model, human operators manually control the speed by monitoring various factors in the plant. In this paper, we propose a neural network-based pallet speed controller which copies human operator knowledge. Actual process data were collected from a sintering plant fer eight months and preprocessed to remove noisy and inconsistent data. A multilayer perceptron was trained using a back-propagation learning algorithm. In on-line testing at the sinter plant, the proposed model reliably controlled pallet speed during normal operation without the help of human operators. Moreover, the duality and productivity was as good as with human operators.

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Pallet speed control in a sintering plant using neural networks (신경회로망을 이용한 소결기 팰릿 속도 제어)

  • Jang, Min;Cho, Sung-Jun
    • Proceedings of the Korea Inteligent Information System Society Conference
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    • 1999.03a
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    • pp.261-270
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    • 1999
  • Sintering transforms powdered ore into lumped ore so that the latter can be used in a blast furnace. The powdered or combined with coke and other materials is loaded into a container and moved along by a pallet while the ignited coke burns. The speed by which the pallet moves determines how much sintering takes place. Since the process is complicated and lacks an accurate mathematical model, human operators manually control the speed by monitoring various factors in the plant. In this paper, we propose a neural network-based pallet speed controller which copies human operator knowledge. Actual process data were collected from a sintering plant for eight months and preprocessed to remove noisy and inconsistent data. A multilayer perceptron was trained using a back-propagation learning algorithm. In on-line testing at the sinter plant, the proposed model reliably controlled pallet speed during normal operation without the help of human operators. Moreover, the quality and productivity was as good as with human operators.

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A MODEL OF RETIREMENT AND CONSUMPTION-PORTFOLIO CHOICE

  • Junkee Jeon;Hyeng Keun Koo
    • Bulletin of the Korean Mathematical Society
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    • v.60 no.4
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    • pp.1101-1129
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    • 2023
  • In this study we propose a model of optimal retirement, consumption and portfolio choice of an individual agent, which encompasses a large class of the models in the literature, and provide a methodology to solve the model. Different from the traditional approach, we consider the problems before and after retirement simultaneously and identify the difference in the dual value functions as the utility value of lifetime labor. The utility value has an option nature, namely, it is the maximized value of choosing the retirement time optimally and we discover it by solving a variational inequality. Then, we discover the dual value functions by using the utility value. We discover the value function and optimal policies by establishing a duality between the value function and the dual value function. The model and approach offer a significant advantage for computation of optimal policies for a large class of problems.

GLOBAL STABILITY OF THE VIRAL DYNAMICS WITH CROWLEY-MARTIN FUNCTIONAL RESPONSE

  • Zhou, Xueyong;Cui, Jingan
    • Bulletin of the Korean Mathematical Society
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    • v.48 no.3
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    • pp.555-574
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    • 2011
  • It is well known that the mathematical models provide very important information for the research of human immunodeciency virus type. However, the infection rate of almost all mathematical models is linear. The linearity shows the simple interaction between the T-cells and the viral particles. In this paper, a differential equation model of HIV infection of $CD4^+$ T-cells with Crowley-Martin function response is studied. We prove that if the basic reproduction number $R_0$ < 1, the HIV infection is cleared from the T-cell population and the disease dies out; if $R_0$ > 1, the HIV infection persists in the host. We find that the chronic disease steady state is globally asymptotically stable if $R_0$ > 1. Numerical simulations are presented to illustrate the results.

Analysis of The Lateral Motion of Tractor-Trailer Combination (I) Operator/Vehicle System Model for Forward Maneuver

  • Torisu, R.;Mugucia, S.W.;Takeda, J.
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 1993.10a
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    • pp.1137-1146
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    • 1993
  • In order to analyze lateral control in the forward manuever of a tractor- trailer combination , a human operator model and a kinematic vehicle model were utilized for the operator/vehicle system. By combining the vehicle and operator models, a mathematical model of the closed-loop operator/vehicle system was formulated. A computer program was developed so as to simulate the motion of the tractor-trailer combination . In order to verify the operator/vehicle system model, the results of the field trials were compared with the simulated results. There was found to be reasonably good agreement between the two.

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A Mathematical Approach of Work Assignment for Human Resource in Software Development (소프트웨어 개발인력 배치를 위한 수학적 업무 배정 방법)

  • Chen, Xiang;Lee, Sang-Joon;Seo, Seong-Chae;Kim, Byung-Ki
    • Journal of Digital Convergence
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    • v.11 no.2
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    • pp.205-214
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    • 2013
  • Team collaboration is becoming commonplace and it is spotlighted in agile software development projects as well. More efficient teamwork in terms of effective team operation and project performance is very important. Heuristic software development staffing method has been used, but algorithm approach is needed to compensate for it. In this paper, we propose a mathematical approaches for staffing developers in teamwork-based software development projects. This consist of six process, and activities in each processor is defined as a mathematical function placement, and functional deployment matrix is used. A case study is presented in order to prove the usefulness of this approach. This paper is a significant research because a mathematical approach of work assignment is developed for human resources by quantitative logic and it deviate from intuitive or heuristic methods used previously.