• Journal of Korean Medical classics
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• v.36 no.3
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• pp.89-128
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• 2023

Objectives : This study aims to diachronically examine the classification systems of all materia medica, followed by categorization and analysis of each category to deduce each category's characteristic. This will provide foundation for further examining classifications of bencao in contemporary herbology. Methods : Classification systems from a total of 93 bencao related texts were collected and categorized. Each category's classification system was analyzed to determine its meaning. The classification systems were compared from a diachronic perspective, to further deduce each system's problem from a historical context. Results : The classification systems of materia medica could be summarized as following three standards: quality, origin, and medical application. In reality, bencao could be generally classified according to origin and medical application. The origin-based classification system provided a stable and flexible classification outline in the expansion process of bencao. The medical application-based classification strengthened the relationship between bencao and illness pattern, improving clinical applicability. Conclusions : In the history of herbology, the two classification systems created the current of herbology through mutual contribution and conflict. We hope that further discussion on the direction towards which classification system of bencao in contemporary herbology should head will proceed based on this study.

• The Journal of Internal Korean Medicine
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• v.27 no.2
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• pp.394-406
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• 2006

Backgrounds and Objectives: Asthma is considered to be an inflammatory disease characterized by airway hyperresponsiveness and Pulmonary eosinophilia. And it is known the structure and function of IL-5, its receptor and the mechnism IL-5 triggered eosinophil accumulation and inflammaion of the airways. At this point of view, we assume which oriental materia medics can the splenocyte inhibit from secreting the IL-S in vitro. Material and Methosds: We used the splenocyte of mouse 8 weeks after its birth, and then cnltivated those into the 2 experimental groups and control group for 48 hours. The culture medium of experimental groups were made of $1{\mu}g/ml,\;10{\mu}g/ml$, oriental materia medics, representative. And the culture media of control group was given no oriental materia medica. Then, we assayed the quantity of cytokine-expression by the Sandwich ELISA. The quantifies of cytokine-expression of the experimental groups were compared with that of the control group which was standardized These method were used for the all of oriental materia medica treated. Results: In this study, we demonstrated that 12 oriental materia medica that inhibit the splenocyte from secreting the IL-5 in both $1{\mu}g/ml,\;and\;10{\mu}g/ml$ culture media. Those were Equiseti Herbs, Sophorae Subprostratae Radix, Moutan Radicis Cortex. Trichosanthis Radix, Buddleiae Flos. Cyperi Rhizoma. Benincasae Semen, Armeniacae Semen. Zedoariae Rhizoma, Astragali Semen, Dolichoris Semen. Lilii Bulbus, Asparagi Radix, Atractylodes Rhizoma White, Polygonati Officinallis Rhizoma. Conculusions: These findinga indicate that some oriental materia medica, specially Antipyretics, Herbs for Resolving Phlegm, Relieving Cough and Calming Wheezing and Herbs for Tonifring and Invigorating effects inhibit the splenocyte from secreting the IL-5. And further study experimented in vivo is needed for treating IL-5-driven inflammatory disease including asthma.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.15
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• pp.6437-6441
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• 2014

Background: Oridonin isolated from Rabdosia rubescens, a plant used to treat cancer in Chinese folk medicine, is one of the most important antitumor active ingredients. Previous studies have shown that oridonin has antitumor activities in vivo and in vitro, but little is known about cell cycle effects of oridonin in gastric cancer. Materials and Methods: MTT assay was adopted to detect the proliferation inhibition of SGC-7901 cells, the cell cycle was assessed by flow cytometry and protein expression by Western blotting. Results: Oridonin could inhibit SGC-7901 cell proliferation, the $IC_{50}$ being $15.6{\mu}M$, and blocked SGC-7901 cell cycling in the $G_2/M$ phase. The agent also decreased the protein expression of cyclinB1 and CDK1. Conclusions: Oridonin may inhibit SGC-7901 growth and block the cells in the $G_2/M$ phase by decreasing Cdk1 and cyclinB1 proteins.

• The Journal of Korean Medicine
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• v.31 no.1
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• pp.57-68
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• 2010

Objectives: Standard is a unified criterion for some repeated things or concepts in a certain scope. It is fundamental to implement standardization in English translation of traditional Korean medicine (TKM) formulae to promote progress in the evaluation of TKM and also to serve in enhancing the efficiency in studies of medical formulae. Methods: We undertook literature research on current Korean and Chinese medicinal formulae in English translation, analyzing 485 Korean formulae and 464 Chinese. We also undertook a comparative study of 102 common English translation of both Korean and Chinese, proposing a constant and effective methods for English translation of medical formulae. Results: To have a precise English translation we classified medical formulae nomenclature in advance. We found that formulae naming can be fundamentally classified into 6 forms which are (a) Materia Medica + Preparation Form, (b) Materia Medica + Indication + Preparation Form, (c) Materia Medica Numbers + Preparation Form, (d) Indication + Preparation Form, (e) Concept + Preparation Form, and (f) Miscellaneous. Based on these findings we could determine that these 6 types ((a)-(f)) can all be translated into English by (1) Materia Medica + Preparation Form and (2) Indication + Preparation Form + of (with) + Materia Medica schemes. In regard to translation of Indication it can follow Noun+~ing participle form. Conclusion: This research provides a common method of TKM medicinal formulae English translation for better understanding, education, training, practice and research in TKM. Consequently, English translation using these methods can serve as the initial study for standardization of TKM medicinal formulae.

• The Journal of Korean Medical History
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• v.31 no.1
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• pp.135-147
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• 2018

Analyzing the Book of Changes, researchers noted that animals and plants utilized as symbols in the Book of Changes were later used as medicinals in East Asian medicine. They found 24 animals and plants utilized as symbols in the Book of Changes; specifically in six statements on the hexagrams and 53 statements on the lines. The animal and plant symbols in 59 statements are more clearly interpreted with the descriptions in the Compendium of Materia Medica. Eleven plants referenced in the Book of Changes were written with their nicknames, causing confusion to the researchers of later times. Using the Compendium of Materia Medica however, these plants can be identified. Livestock were mentioned 34 times among the 59 statements, with horse and cattle being the most often at eight times, each. They are subdivided according to their sex and color. The writers of the Book of Changes constructed an elaborate symbol system with the animals that are familiar to people, and which, through this research, has been decoded through cross references to the Compendium of Material Medica.

• Journal of Korean Medical classics
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• v.24 no.5
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• pp.67-81
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• 2011

Objective : Several kinds of food could be materia medica within food-therapy in oriental medicine. "Sikryochanyo" is a book about food-therapy totally. So there are many kinds of food are treated as materia medica. Method : Finding out cases of food-therapy with chicken in "Sikryochanyo" Result : In "Sikryochanyo", there were many ways of food-therapy with chiken. Chicken was treated as materia medica even though it was a forbidden food when someone got sik especially with fever because of the effects. Conclusion : On several types such as parts, colors, methods to make, of chicken, there are plenty of usage with its own effectiveness.

• Natural Product Sciences
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• v.2 no.1
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• pp.14-18
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• 1996

A new phenolic glycoside named mussaendoside L (1), along with four known iridoidal glycosides $(2{\sim}5)$ were isolated from the aerial parts of Mussaenda pubescens Ait.f. Their structures were elucidated on the basis of chemical and spectroscopic evidence.

• Proceedings of the Korean Society of Toxicology Conference
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• 2001.10a
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• pp.203-204
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• 2001

Background and Aim: Transitional cell carcinoma (TCC) of the bladder represents the fifth most prevalent malignancy in Western population, with peak incidence found in males of the 50- to 70-year-old age group. A major problem in the management of bladder cancer is the low sensitivity of a large proportion (approximately 40%) among bladder tumors to chemotherapy and the high risk for recurrence of bladder tumors after transurethral resection.(omitted)

• Bulletin of the Korean Chemical Society
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• v.34 no.10
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• pp.3143-3146
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• 2013

• Bulletin of the Korean Chemical Society
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• v.34 no.4
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• pp.1023-1024
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• 2013