• 한국수정란이식학회:학술대회논문집
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• 한국수정란이식학회 1998년도 춘계학술대회 및 워크숍
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• pp.12-28
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• 1998

The technology of creating transgenic animals has a potential value in improving productivity and disease resistance of animals, gene therapy, drug pharming and production of model animals for certain diseases. Up to date, fairly low success rate of production of transgenic animals and a pronounced variability with respect to the expression of transgenes have been much observed. The mechanisms how to integrate the injected genes with a certain part of the genomes are unknown yet. Many techniques in gene transfer, beside microinjection, have been introduced and explored thus to improve the production efficiency of transgenic animals. In this article, the methods and efficiency of gene-transfer techniques, the detection and preselection of transgenes in embryos by PCR- and GFP-screenings and cloning of preselected transgenic embryos by nuclear transplantation are described and discussed. Some experimental results showed that the early screening and selection of integration of the injected gene with embryonic genome by polymerase chain reaction(PCR) and green fluorecence protein(GFP) were promising methods. Further, the application of nuclear transplantation technology to cloning and multiplication of the positively integrated genes in the cleaving embryos and embryonic cells will be beneficially used for the mass production of transgenic embryos and consequently improving the production efficiency in transgenic animals.

• 한국지반공학회논문집
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• 제23권9호
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• pp.51-63
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• 2007

암반에 근입된 현장타설말뚝의 주면거동특성을 분석하고자, 편마암질의 풍화암/연암지역에서 현장 말뚝재하시험(압축재하 4회, 인발시험 5회)을 수행하였다. 이를 통해 암반 풍화, 굴착면 거칠기, 말뚝 직경, 재하방향 등의 요소들이 암반 근입 현장타설말뚝의 주면 전단거동을 결정짓는 주요요소임을 확인할 수 있었다. 본 연구에서는 국내에서 수행된 암반 근입 현장타설말뚝의 재하시험 사례를 토대로 국내 암반조건을 반영한 극한주면마찰력($f_{max}$)을 제안하였다.

• 대한의용생체공학회:의공학회지
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• 제3권1호
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• pp.3-8
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• 1982

Solute transfer in artificial kidney dialyzers was analyzed using Kedem-Katcha- Isky's description on membrane transport. Mass transfer coefficient, K was deduced from the diffusive clearance of commercial hemodialyzers. It can to seen that Kd increases with the increase of blood flow rate, which means that there is substantial resistance in the blood phase for solute transport. Total clearance was estimated with the Werynski's formula. The increase in total clearance due to ultrafiltration was most significant for middle molecules like vitamin Bla, however that for smaller molecules such as urea and creatinine was minimal.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1998년도 추계학술대회
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• pp.237-238
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• 1998

The kinetics of sulfite oxidation must be fast and the concentration of sulfite must be low to emulate oxygen uptake by blood. The kinetics were studied yielding a first order rate constant in sulfile, zero order in oxygen. Limitations of the technique were evaluated using the experimental rate constant and an adaptation of Lightfoot's approximation, while the reaction of hemoglobin is reversible and essentially instantaneous, that for sulfite is irreversible and finite. Thus if the approach to saturations not monotonic or if the mass transfer resistance is significantly lowered, e. g. when blood film thicknesses are thinner than a few hundred microns, deviations may occur.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2008년도 추계학술대회B
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• pp.2106-2109
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• 2008

Nanofluids have been studied as possible alternatives for heat transfer fluids to improve the efficiency of heat exchangers. There are deviations of measured effective thermal conductivities between research-groups, and the mechanisms of the effective thermal conductivity enhancement of nanofluids are not confirmed yet. In this study, the effects of particle shape on the effective thermal conductivity enhancement are discussed and presented as a possible explanation of the deviations. The particle motion effect is found to be negligible for nanofluids of high aspect ratio cylindrical particles, which is believed to be important for nanofluids of spherical particles, while the percolation network formation and contact resistance play dominant roles in determining the effective thermal conductivity.

• 공업화학
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• 제7권2호
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• pp.237-244
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• 1996

미세공의 중공사 모듈을 이용한 액-액추출은 단위부피당 표면적이 크므로 기존 추출장치들에 비해 신속히 진행된다, 모듈내에서 추출제와 원료액은 빠른 속도로 접촉하며 두 흐름이 완전히 독립적이므로 부하나 편류현상이 일어나지 않는다. 본 연구에서는 소수성 중공사 모듈을 사용하여 수용액 중에 미량으로 존재하는 Fe(II)와 Ni(II)을 추출하기 위해 TOA 및 EHPNA를 추출제로 사용하여, 그 추출선택성을 고찰하였다. 또한, 중공사 모듈에서의 율속단계를 결정하기 위해 막 내 외부 유속의 영향을 검토하였다. 이로부터, 소수성 중공사 내에서 분배계수가 큰 계에 대한 추출조작의 경우는 막내부에서의 물질전달과정이 총괄물질전달을 지배함을 확인하였으며, 본 연구를 통한 $K_w$와 소수성 중공사 내부유속 $v_t$와의 상관관계는 $K_w{\frac{d}{D}}=6.22\(\frac{d^2v_t}{LD}\)^{1/3}$과 같았다. 반면, 분배계수가 낮은 경우, 세공 내에서의 추출반응이 원활하지 못하기 때문에 막내부 저항의 영향이 막저항의 영향보다 작았다. 따라서, 분배계수가 큰 계에서는 소수성 막을 사용하는 것이 효과적임을 예측할 수 있었다.

• 한국전산유체공학회지
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• 제21권1호
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• pp.86-93
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• 2016

In this paper, heat transfer characteristics of pulsating heat pipes are investigated with the diameter and the number of tubes through the computational analysis of thermal flow. The numerical simulation includes the phase change precess with VOF model using OpenFOAM software. The numerical code is modified for the phase change to occur with saturation temperature. The numerical results are compared with the previous ones to validate the present code. The resonable results have been obtained based on the mass transfer time relaxation parameter considering the density ratio. When the ratio of length to diameter and the number of tubes are on the decrease, the thermal resistances also tends to decrease in the pulsating heat pipes. These numerical results will supply the base line data to design and to manufacture the pulsating heat pipe.

• International Journal of Air-Conditioning and Refrigeration
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• 제9권3호
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• pp.27-35
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• 2001

Heat transfer characteristics of a heat exchanged for low temperature waste heat recovery using oscillating capillary tube heat pipe (OCHP) were evaluated against the charging ratio variation of working fluid and various working fluids. R-l42b, R-22 and R-290 were used as working a 2.6mm in outside diameter, 1.44mm in inside diameter with 101m length and 140 turns. Charging ratio of working fluid was 40% and 50%. water was used as secondary fluid. Inlet temperature and mass velocity for each secondary fluid were 297 K, 280 K and 9~27 $4kg/m^2s$, respectively. From experimental results, it was found that heat transfer performance of R-22 was higher than those of R-142b and R-290 and it was proportional to Figure of Merit for thermosyphon. As a result, it was thought that R-22 was the most reasonable working fluid of waste heat recovery for low temperature waste heat recovery.

• 설비공학논문집
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• 제12권7호
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• pp.659-666
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• 2000

Heat transfer characteristics of a heat exchanger for low temperature waste heat recovery using oscillating capillary tube heat pipe were evaluated against the charge ratio variation of working fluid and various working fluids. R-l42b, R-22 and R-290 were used as working fluids. The heat exchanger was composed of heat pipe with capillary tube bundles, having a 2.6mm in outer diameter, 1.4mm in inner diameter with 101m long, and 40 turns. Charge ratio of working fluid was 40% and 50%. Water was used as secondary fluid. Inlet temperature and mass velocity for each secondary fluid were 297 K, 280 K and9~27 kg /$m^2s$,, respectively. From experimental results, it was found that heat transfer performance of R-22 was higher than those of R-l42b and R-290 and it was proportional to Figure of merit for thermosyphons. As a result, it was thought that R-22 was the most suitable working fluid of waste heat recovery for low temperature waste heat recovery.

• 한국지반공학회논문집
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• 제22권7호
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• pp.23-35
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• 2006

본 연구에서는 암반에 근입된 현장타설말뚝의 주면하중전이특성을 분석하기 위하여, 주요 영향요소(일축압축강도, 거칠기, 수직강성, 초기구속응력, 재료성질)에 따라 일정수직강성(Constant Normal Stiffness, CNS)조건의 직접전단시험을 수행하였다. 그 결과 암반에 근입된 현장타설말뚝의 주변하중전이특성을 3구간으로 이상화할 수 있었으며, 각 구간에서의 거동을 지배하는 주요 요소의 영향 및 그에 따른 거동을 파악할 수 있었다. 이를 토대로 암반의 절리 및 풍화상태를 나타내는 GSI(Geological Strength Index)를 이용한 Hoek-Brown 파괴기준(1997)을 적용하여, 암반에 근입된 현장타설말뚝의 굴착면 거칠기를 고려한 새로운 주면 하중전이함수를 제안하였다. 제안된 하중전이함수는 기존 7본의 말뚝 재하시험 결과와 비교분석을 수행하였으며, 그 결과 본 제안식이 암반 굴착면의 거칠기 및 암반특성을 적절히 반영함을 알 수 있었다.