• 대한수학회논문집
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• 제21권2호
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• pp.363-374
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• 2006

A new bivariate beta distribution based on the Appell function of the third kind is introduced. Various representations are derived for its product moments, marginal densities, marginal moments, conditional densities and conditional moments. The method of maximum likelihood is used to derive the associated estimation procedure as well as the Fisher information matrix.

• 응용통계연구
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• 제9권1호
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• pp.1-15
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• 1996

본 논문은 질병발생집단의 감염율이 질병발생집단내 감염되지 않은 개체들에 대한 어떤 처치효과가 감염율에 어떻게 영향을 받는가를 알아보기 위한 통계적 분석모형으로 연속적 분석모형을 제시하고, 모형내 미지모수들을 추정하기 위한 방법을 논의하고 있다.

• Journal of the Korean Data and Information Science Society
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• 제27권4호
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• pp.1083-1090
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• 2016

In clinical studies, different types of outcomes (e.g. repeated measures data and time-to-event data) for the same subject tend to be observed, and these data can be correlated. For example, a response variable of interest can be measured repeatedly over time on the same subject and at the same time, an event time representing a terminating event is also obtained. Joint modelling using a shared random effect is useful for analyzing these data. Inferences based on marginal likelihood may involve the evaluation of analytically intractable integrations over the random-effect distributions. In this paper we propose a joint HGLM approach for analyzing such outcomes using the HGLM (hierarchical generalized linear model) method based on h-likelihood (i.e. hierarchical likelihood), which avoids these integration itself. The proposed method has been demonstrated using various numerical studies.

• 응용통계연구
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• 제18권1호
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• pp.67-81
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• 2005

프레일티모형에 대한 기존의 추론방법은 동측치가 많은 경우에 그 성능이 떨어진다. 그 이유는 사용된 경험적 우도함수가 동측치가 많은 자료에는 적합하지 않기 때문이다. 본 논문에서는 동측치가 많은 프레일티 모형에서의 새로운 추론방법을 제안한다. 이항형태의 경험적우도함수를 바탕으로 베이지안 부스트랩을 사용하여 모수의 사후분포를 구한다. 제안된 방법의 장점은 기존에 제안된 주변최대우도추정량에 비하여 계산이 수월하고 안정적인 결과를 제공하는데 있다. 이를 실증적으로 비교하기 위하여 제안된 방법을 주변최대우도추정량과 가상실험을 통하여 비교한다.

• Communications for Statistical Applications and Methods
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• 제15권2호
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• pp.161-171
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• 2008

This study discusses Johnson's $S_U$-normal distribution capturing a wide range of non-normality in various regression models. We provide the likelihood inference using Johnson's $S_U$-normal distribution, and propose a likelihood ratio (LR) test for normality. We also apply the $S_U$-normal distribution to the binary and censored regression models. Monte Carlo simulations are used to show that the LR test using the $S_U$-normal distribution can be served as a model specification test for normal error distribution, and that the $S_U$-normal maximum likelihood (ML) estimators tend to yield more reliable marginal effect estimates in the binary and censored model when the error distributions are non-normal.

• Journal of the Korean Statistical Society
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• 제21권2호
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• pp.187-200
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• 1992

Samples are often found to be too heterogeneous to be explained by a one-parameter family of models in the sense that the implicit mean-variance relationship in such a family is violated by the data. This phenomenon is often called over-dispersion. The most frequently used method in dealing with over-dispersion is to mix a one-parameter family creating a two parameter marginal mixture family for the data. In this paper, we investigate performance of estimators such as maximum likelihood estimator, method of moment estimator, and maximum quasi-likelihood estimator in negative binomial and beta-binomial distribution. Simulations are done for various mean parameter and dispersion parameter in both distributions, and we conclude that the moment estimators are very superior in the sense of bias and asymptotic relative efficiency.

• Communications for Statistical Applications and Methods
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• 제24권3호
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• pp.291-301
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• 2017

It is well known in a small sample that the maximum likelihood (ML) approach for variance components in the general linear model yields estimates that are biased downward. The ML estimate of residual variance tends to be downwardly biased. The underestimation of residual variance, which has implications for the estimation of marginal effects and asymptotic standard error of estimates, seems to be more serious in some limited dependent variable models, as shown by some researchers. An alternative frequentist's approach may be restricted or residual maximum likelihood (REML), which accounts for the loss in degrees of freedom and gives an unbiased estimate of residual variance. In this situation, the REML estimator is derived in a censored regression model. A small sample the REML is shown to provide proper inference on regression coefficients.

• Communications for Statistical Applications and Methods
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• 제21권2호
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• pp.193-200
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• 2014

It was recognized by some researchers that the disturbance variance in a censored regression model is frequently underestimated by the maximum likelihood method. This underestimation has implications for the estimation of marginal effects and asymptotic standard errors. For instance, the actual coverage probability of the confidence interval based on a maximum likelihood estimate can be significantly smaller than the nominal confidence level; consequently, a Bayesian estimation is considered to overcome this difficulty. The behaviors of the maximum likelihood and Bayesian estimators of disturbance variance are examined in a fixed effects panel regression model with a limited dependent variable, which is known to have the incidental parameter problem. Behavior under random effect assumption is also investigated.

• 응용통계연구
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• 제26권3호
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• pp.389-399
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• 2013

본 연구에서는 가우시안 과정회귀방법을 소개하고 시계열 마이크로어레이 유전자 발현데이터에 대해 가우시안 과정회귀를 적용한 사례를 보이고자한다. 가우시안 과정회귀를 적합하여 로그 주변우도함수 비를 이용한 유전자를 선별방법에 대한 모의실험을 통해 민감도, 특이도, 위발견율 등을 계산하여 선별방법으로의 활용성을 보였다. 실제 효모세포주기 데이터에 대해 제곱지수공분산함수를 고려한 가우시안 과정회귀를 적합하여 로그 주변우도함수 비를 이용하여 차변화된 유전자를 선별한 후, 선별된 유전자들에 대해 가우시안 모형기반 군집화를 하고 실루엣 값으로 군집유효성을 보였다.

• Communications for Statistical Applications and Methods
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• 제22권5호
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• pp.507-518
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• 2015

It is not easy to select a linear mixed model since the main interest for model building could be different and the number of parameters in the model could not be clearly defined. In this paper, performance of conditional Akaike Information Criteria and its bias-corrected version are compared with marginal Bayesian and Akaike Information Criteria through a simulation study. The results from the simulation study indicate that bias-corrected conditional Akaike Information Criteria shows promising performance when candidate models exclude large models containing the true model, but bias-corrected one prefers over-parametrized models more intensively when a set of candidate models increases. Marginal Bayesian and Akaike Information Criteria also have some difficulty to select the true model when the design for random effects is nested.