• Environmental Analysis Health and Toxicology
• /
• v.31
• /
• pp.26.1-26.9
• /
• 2016

Objectives Korea's Act on the Registration and Evaluation of Chemicals (K-REACH) was enacted for the protection of human health and the environment in 2015. Considering that about 2000 new substances are introduced annually across the globe, the extent of animal testing requirement could be overwhelming unless regulators and companies work proactively to institute and enforce global best practices to replace, reduce or refine animal use. In this review, the way to reduce the animal use for K-REACH is discussed. Methods Background of the enforcement of the K-REACH and its details was reviewed along with the papers and regulatory documents regarding the limitation of animal experiments and its alternatives in order to discuss the regulatory adoption of alternative tests. Results Depending on the tonnage of the chemical used, the data required ranges from acute and other short-term studies for a single exposure route to testing via multiple exposure routes and costly, longer-term studies such as a full two-generation reproducibility toxicity. The European Registration, Evaluation, Authorization and Restriction of Chemicals regulation provides for mandatory sharing of vertebrate test data to avoid unnecessary duplication of animal use and test costs, and obligation to revise data requirements and test guidelines "as soon as possible" after relevant, validated replacement, reduction or refinement (3R) methods become available. Furthermore, the Organization for Economic Cooperation and Development actively accepts alternative animal tests and 3R to chemical toxicity tests. Conclusions Alternative tests which are more ethical and efficient than animal experiments should be widely used to assess the toxicity of chemicals for K-REACH registration. The relevant regulatory agencies will have to make efforts to actively adopt and uptake new alternative tests and 3R to K-REACH.

• Journal of Periodontal and Implant Science
• /
• v.44 no.4
• /
• pp.184-193
• /
• 2014

Purpose: The aim of the present study was to evaluate the in vivo accuracy of flapless, computer-aided implant placement by comparing the three-dimensional (3D) position of planned and placed implants through an analysis of linear and angular deviations. Methods: Implant position was virtually planned using 3D planning software based on the functional and aesthetic requirements of the final restorations. Computer-aided design/computer-assisted manufacture technology was used to transfer the virtual plan to the surgical environment. The 3D position of the planned and placed implants, in terms of the linear deviations of the implant head and apex and the angular deviations of the implant axis, was compared by overlapping the pre- and postoperative computed tomography scans using dedicated software. Results: The comparison of 14 implants showed a mean linear deviation of the implant head of 0.56 mm (standard deviation [SD], 0.23), a mean linear deviation of the implant apex of 0.64 mm (SD, 0.29), and a mean angular deviation of the long axis of $2.42^{\circ}$ (SD, 1.02). Conclusions: In the present study, computer-aided flapless implant surgery seemed to provide several advantages to the clinicians as compared to the standard procedure; however, linear and angular deviations are to be expected. Therefore, accurate presurgical planning taking into account anatomical limitations and prosthetic demands is mandatory to ensure a predictable treatment, without incurring possible intra- and postoperative complications.

• The Korean Society of Law and Medicine
• /
• v.11 no.2
• /
• pp.181-208
• /
• 2010

Maternity services is often perceived as a troublesome business and obstetric litigation is on the increase in Western countries. Overall, the number of claim and cost of litigation to the NHS Litigation Authority (NHSLA) from maternity services in the UK is increasing every year. Maternity services account for 60-70% of the total sum paid. This has widespread implications for both the individual practitioners and the institutions where they work, due to increasing malpractice insurance premiums. Fear of litigation is also attracting fewer medical graduates into the specialty, leading to a recruitment crisis in obstetrics and gynaecology. The litigation process can cause pain, suffering and distress to clinicians as well as to the patients and their families. Litigation in maternity services is the result of a complex of events when malpractice (presumed or real) impacts on the attitude of pregnant women and their environment. In such complexity, information is mandatory but may often be misinterpreted. If messages are not tailored to the receiver's capacity, communicating well with the pregnant patient becomes crucial. Therefore, to reduce medicallegal issues in obstetrics, increasing attention and an applicable standard of obstetric care to avoid negligence and medical errors should go along with other measures. Considering UK's experiences, NHS redress scheme make it easier to pursue small claims and birth related claims, without necessarily reducing the number of claims processed through the conventional legal system and perhaps encouraging even more of them. The task of dealing with the greater number of inquiries into their practice would inevitably create an added burden for clinicians and hospital managers. Thus further proposals are required to limit the cost of processing inflated claims and to consider whether clinicians should be given some protection from litigation alleging a failure to prevent birth related impairment.

• Proceedings of KOSOMES biannual meeting
• /
• 2006.05a
• /
• pp.33-40
• /
• 2006

To promote the consistent and effective implementation of IMO instruments such as SOLAS, MARPOL, STCW, LL, TONNAGE, COLREG IMO has adopted voluntary IMO member state audit. This audit scheme is voluntary audit which will be carried out on a voluntary basis, at the request cf the member state to be audited. Nevertheless, the Korea government is preparing the implementation of the audit scheme to strengthen the competitiveness in shipping and shipbuilding industries. In this paper, we investigated the actual conditions of implementation of mandatory IMO instruments and carried out a feasibility study by assessing the cost to be audited and positive effects expected by introducing the audit scheme. As a result of cost benefit analysis we obtained high benefit-cost ratio.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.19 no.5
• /
• pp.122-130
• /
• 2018

The International Maritime Organization has enacted mandatory performance standards for protective coatings (PSPC), and as a result, shipyards must perform 2R or 3-pass milling on the edges of color plates. However, manual milling could result in many problems in terms of work environment and productivity. Therefore, it is necessary to develop an edge milling automation system that can satisfy the regulations. In this study, a basic design for an edge milling automation system was developed for standard color plates, and the machining process was established by applying shape recognition and a machining path generation algorithm. In addition, operating software was developed, and suitable milling conditions were derived based on the results of a milling test. The results could be used to build an automation system that meets the PSPC requirements and improve productivity.

• Journal of the Korea Organic Resources Recycling Association
• /
• v.28 no.2
• /
• pp.31-40
• /
• 2020

As private sewage treatment facilities in Korea are constantly concerned about the distribution and poor construction of defective products, minimum standards for each unit process applicable to the planning and design of sewage treatment facilities are deemed necessary. The problems and requirements of the analysis results of the operation status discussed in this study are as follows. 1) Strengthening education of supervisor of private sewage treatment facility. 2) Poor operation and management of Sewage treatment facilities. 3) A mandatory review of sewage treatment facilities for less than 2 ㎥/day of facilities other than sewage treatment zones. 4) Necessity of management of sewage treatment facility in feedstocks. 5) As a result of the technical review, Improvement plans for Ineligible facility are needed. It is also necessary to prepare a guidebook for design construction and maintenance by investigating and analyzing guidelines and data related to domestic and foreign private sewage treatment facilities.

• Journal of the Korean Professional Engineers Association
• /
• v.28 no.4
• /
• pp.14-20
• /
• 1995

Discourses on global environment are not only limited to the matter of simple environmen-tal protection but also going to an imperative that every country should take the environ-mental aspects into more consideration, and if necessary even proceed to modify its own strategies for economic growth. It is because scores of existing International conventions and agreements on environmental caused tend to combine the environmental issues with trade sanctions and financial assistances in order to ensure a mandatory power in pushing themselves through on a global dimension. Particularly noteworthy is the so -called Green Round(GR) which substantially associates the Issues of environmental protection with some sanctions in international trade, its rationale is quite simple. The differentiated production costs rising from the difference in environmental standards among different countries may affect national competitiveness in in-ternational trade, therefore a need does exist to countervail this difference. In reality, however, severe dissention seems to have been exposed between the developed and developing countries around this matter, because national interests and priorities in national goals considerably differ among respective countries. Greenhouse gases such as carbon dioxide which caused global warming are mostly released from the combustion of fossil fuels. The perfect removal of released $CO_{2}$ is impossible with existing technologies, and moreover, it's not payable in economical terms. Therefore it will be more effective and desirable to make more efforts to prevent the release of the $CO_{2}$ it- self through energy conservation involving the development and promotion of clean and high-efficient energy technologies and energy sources, and the development and promotion of new & renewable energy resources, and so on. One of important national tasks In our country is to establish an Energy Policy consider-ing environmental impacts since Korea depends most of its energy consumption on the fossil fuels such as oil and coal.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.13 no.6
• /
• pp.2528-2539
• /
• 2012

In the 21st century, knowledge is an important asset to improve productivity in the business world. In today's rapidly changing business environment, companies have rigorously brought in knowledge management system in order to secure the sustainable competitiveness and effective knowledge management. Knowledge management has now become mandatory, not optional. Today many companies which have built knowledge management on top of information technology and hardware-based infrastructure are having a difficulty in creating organizational culture in knowledge management. Even though companies have invested substantial time and money in knowledge management, the performances have not met their expectations. To solve this problem, software oriented strategy for knowledge management such as education and networking is more needed rather than hardware oriented strategy such as information technology systems. Though the knowledge management framework suggested in this study is exploratory, this study contributes to the clarification of the critical elements that companies which are about to build knowledge management should take in account.

• Journal of the Korea Institute of Information Security & Cryptology
• /
• v.23 no.3
• /
• pp.515-530
• /
• 2013

The results of investigations into marine incidents have become an important basis in determining not only possible causes, but also the extent of negligence between the perpetrator and victim. However, marine incidents occur under special circumstances i.e. the marine environment, and this leads to difficulties in identifying causes due to problems in scene preservation, reenactment and acquisition of witnesses. Given the aforementioned characteristic of marine incidents, the International Convention for the Safety of Life at Sea (SOLAS) has adopted mandatory regulations on the carriage of Voyage Data Recorders (VDRs) and Automatic Identification Systems (AIS) for ships of a certain gross tonnage and upwards, so as to reflect recent developments in radio communication and marine technology. Adopted to provide an international standard for investigations and to promote cooperation, the Code of the International Standards and Recommended Practices for a Safety Investigation into a Marine Casualty or Marine Incident (Casualty Investigation Code) recommends member states to build capacity for analysis of VDR data. Against this backdrop, this paper presents methods for efficient investigations into the causes behind marine incidents based on data analysis of VDR, which serves as the black box of ships, as well as digital forensic techniques.

• Proceedings of the KIEE Conference
• /
• 2005.11b
• /
• pp.122-124
• /
• 2005

Underground distribution system is a trend due to the successive development of metropolitan area and satellite cities and the environment of the commercial and residential areas. The high quality of electricity, which is related with the minimal outage duration time due to the maintenance work for the underground distribution line, is mandatory. Hence, the construction method and tools for the outage-free maintenance construction have been required for underground distribution system. So far, all the efforts for outage-free maintenance for the underground distribution have been limited only to the survey for foreign countries situation and the theoretical provision; thus, It is required to develop the various construction method and the application tools. Differently from the aerial line, the construction of the underground cable is complicated and the insulation distance between conductor and shield should be maintained in loadmaking/breaking operation, though the apparatus connected with cable is a deadfront type. Also since the apparatus is installed above ground, by-pass of faulted area at busy area needs a variety of high technologies. Therefore, in this these, the authors introduce the development status of the loadbreak connectors, connection facilities, outage-free maintenance system for secondary side, a secondary auxiliary bushing and additional tools so that there can be more progress on this field.