• Title/Summary/Keyword: M_2\

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Genome wide identification of Staufen2-bound mRNAs in embryonic rat brains

  • Maher-Laporte, Marjolaine;DesGroseillers, Luc
    • BMB Reports
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    • v.43 no.5
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    • pp.344-348
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    • 2010
  • Messenger ribonucleoprotein particles (mRNPs) are used to transport mRNAs along neuronal dendrites to their site of translation. Staufen2 is an mRNA-binding protein expressed in the cell bodies and cellular processes of different brain cells. It is notably involved in the transport of dendritic mRNAs along microtubules. Its knockdown expression was shown to change spine morphology and impair synaptic functions. However, the identity of Staufen2-bound mRNAs in brain cells is still completely unknown. As a mean to identify these mRNAs, we immunoprecipitated Staufen2-containing mRNPs from embryonic rat brains and used a genome wide approach to identify Staufen2-associated mRNAs. The genome wide approach identified 1780 mRNAs in Staufen2-containing mRNPs that code for proteins involved in cellular processes such as post-translational protein modifications, RNA metabolism, intracellular transport and translation. These results represent an additional and important step in the characterization of Staufen2- mediated neuronal functions in rat brains.

BIRECURRENT HYPERSURFACES OF A RIEMANNIAN MANIFOLD WITH CONSTANT CURVATURE

  • Choe, Yeong-Wu
    • Bulletin of the Korean Mathematical Society
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    • v.26 no.2
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    • pp.159-164
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    • 1989
  • Let M be a hypersurface of dimension n(.geq.2) in an (n+1)-dimensional real space form over bar M(c) with constant curvature c and H the second fundamental tensor of M. M is said to be birecurrent if here exists a covariant tensor field .alpha. of order 2 such that .del.$^{2}$H=H .alpha., where .del. is the connection of M. Also, M is said to be recurrent if there exists a 1-form .betha. such that .del.H=H .betha.. Matsuyama [2] recently proved that a recurrent hypersurface M in a real space form is locally symmetric and a complete irreducible birecurrent hypersurface M in a real space form is recurrent. The main purpose of this paper is to characterize the birecurrent or recurrent hypersurface M of a Riemannian manifold with constant curvature c and to prove that M is classified as a cylinder, $M^{n}$ (c) or ( $c_{1}$)* $M^{n-r}$ ( $c_{2}$) where 1/ $c_{1}$+1/ $c_{2}$=1/c.

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INJECTIVE REPRESENTATIONS OF QUIVERS

  • Park, Sang-Won;Shin, De-Ra
    • Communications of the Korean Mathematical Society
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    • v.21 no.1
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    • pp.37-43
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    • 2006
  • We prove that $M_1\longrightarrow^f\;M_2$ is an injective representation of a quiver $Q={\bullet}{\rightarrow}{\bullet}$ if and only if $M_1\;and\;M_2$ are injective left R-modules, $M_1\longrightarrow^f\;M_2$ is isomorphic to a direct sum of representation of the types $E_l{\rightarrow}0$ and $M_1\longrightarrow^{id}\;M_2$ where $E_l\;and\;E_2$ are injective left R-modules. Then, we generalize the result so that a representation$M_1\longrightarrow^{f_1}\;M_2\; \longrightarrow^{f_2}\;\cdots\;\longrightarrow^{f_{n-1}}\;M_n$ of a quiver $Q={\bullet}{\rightarrow}{\bullet}{\rightarrow}{\cdots}{\rightarrow}{\bullet}$ is an injective representation if and only if each $M_i$ is an injective left R-module and the representation is a direct sum of injective representations.

A BIFURCATION ANALYSIS FOR RADIALLY SYMMETRIC ENERGY MINIMIZING MAPS ON ANNULUS

  • Chi, Dong-Pyo;Park, Gie-Hyun
    • Communications of the Korean Mathematical Society
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    • v.9 no.2
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    • pp.355-359
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    • 1994
  • It would be interesting to know if energy minimizing harmonic maps between manifolds have symmetric properties when the manifolds under consideration have some. In this paper, we consider among others radial symmetry. A radially symmetric manifold M of dimension m is the one with a point, called a pole, and an O(m) action as an isometric rotation with respect to the pole, or more precisely a radially symmetric manifold M has a coordinate on which the metric is of the form $ds_{M}$$^2$ = d$r^2$ + m(r)$^2$d$\theta^2$ for some function m(r) depending only on r. Of course m(0) = 0, m'(0) = 1, and when m(r) = r, (M, $ds_{ M}$/$^2$) is the Euclidean space $R^2$.(omitted)

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Optimization of the Sucrose and Ion Concentrations for Saikosaponin Production in Hairy Root Culture of Bupleurum falcatum

  • Ahn, Jun-Cheul;Chong, Won-Seog;Kim, Young-Soon;Hwang, Baik
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.11 no.2
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    • pp.121-126
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    • 2006
  • Saikosaponin productivity was examined in a Bupleurum falcatum L. BFHR2 hairy root culture in response to changes in the sucrose content $(2{\sim}8%)$, nitrogen content $(0{\sim}250mM\;NH_4NO_3)$, phosphate content $(0{\sim}12mM\;NaH_2PO_4)$, and the potassium content $(0{\sim}87.2 mM\; KCl)$ of the culture media. We found that the conditions for maximal saikosaponin production differed from those for optimal root growth. Highest saikosaponin yield was achieved for 8% sucrose, 62mM $NH_4NO_3$ 1.2 mM $NaH_2PO_4$, and 0.5mM KCl.

Effects of the Temperature and Light Intensity on the Growth and Microcystin Production of Three Species of Microcystis (M. aeruginosa, M. ichthyoblabe, M. viridis) (Microcystis 3종(M. aeruginosa, M. ichthyoblabe, M. viridis)의 성장과 microcystins 생성에 대한 온도 및 조도의 영향)

  • Lee, Kyung-Lak;Jheong, Weon-Hwa;Kim, Jin-Hee;Kim, Han-Soon
    • Korean Journal of Ecology and Environment
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    • v.43 no.3
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    • pp.400-408
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    • 2010
  • The growth and microcystins production characteristics of three species of Microcystis (M. aeruginosa, M. ichthyoblabe, M. viridis) isolated from Yeongchun dam and Ankei dam in Kyungpook Province, South Korea were investigated at temperatures of $15{\sim}35^{\circ}C$ and light intensities of $35{\sim}180\;{\mu}mol\;m^{-2}\;s^{-1}$. All of the three species exhibited the highest growth rates (${\mu}_{max}$) over the $30^{\circ}C$. The maximum growth rates of M. aeruginosa and M. ichthyoblabe was observed at $70\;{\mu}mol\;m^{-2}\;s^{-1}$, while M. viridis showed maximum growth rate at $35\;{\mu}mol\;m^{-2}\;s^{-1}$. The maximum production of total microcystins was observed at $20^{\circ}C$, and the production of microcystins decreased according as temperature increase. The highest microcystins production of M. aeruginosa, M. ichthyoblabe and M. viridis observed at light intensities of $120\;{\mu}mol\;m^{-2}\;s^{-1}$, $70\;{\mu}mol\;m^{-2}\;s^{-1}$ and $35\;{\mu}mol\;m^{-2}\;s^{-1}$, respectively. The concentration of microcyst in production and microcystin types of three species according to temperatures and light intensities showed clear difference between the species.

A study on the Plan Modular Establishment for the Development of Wooden Dwelling Model - Focused on the Post & Beam Structure - (목조주택 모형개발을 위한 평면모듈 설정에 대한 연구 - 기둥-보 방식 구조를 중심으로 -)

  • Kang, Man-Ho;Joo, Seok-Joong;Kim, Jae-Deok
    • Journal of the Korean housing association
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    • v.18 no.1
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    • pp.141-148
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    • 2007
  • In this research, to develope wooden house model with post & beam structure which is commensurate with domestic environment, we analyzed the size and module of a unit space and space organization of existing habitation, then, based on the result, we tried to suggest general wood house modules. For this, we investigated 98 floor plans for 30 pyeong apartment in Seoul, Gyounggi-do, Gwangju, and Jeolla-do. The results are showed as follows. 1) It has shown that 7 posts distances are available in 2 bay floor plan type - 3.0 m, 3.3 m, 3.6 m, 3.9 m, 4.2 m, 4.5 m, and 4.8 m. 2) It has shown that 8 posts distances are available in 3 bay floor plan type - 3.0 m, 3.3 m, 3.6 m, 3.9 m, 4.2 m, 4.5 m, 4.8 m, and 5.1 m. It was concluded as follows, applying the standard of regulations of horizontal modular coordination design, from $\ulcorner$the standard of modular coordination design in architecture(KSF 1525)$\lrcorner$. 1) The available widths are 3.0 m, 3.3 m, 3.6 m, 4.2 m, and 4.8 m, and the available depths are 3.0 m, 3.3 m, 3.6 m, and 4.2 m. 2) To guarantee a space through post module of a room combination, we can use a module of 3.6 m, 4.2 m, 4.8 m except 3.0 m, 3.3 m among available modules. The module investigated in post & beam structure wooden house is applied in basic 6 floor plans as follows. 1) When organize the room on the basis of tile module of 3.6 m, 4.2 m, it was possible to organize the floor plan. 2) After arranging main room, making practical application of variableness which is advantage of post & beam structure, putting to practical use of extra space that becomes the combination of atypical room such as kitchen, dining room, and bathroom, it was possible to organize the floor plan of the residence. 3) It is possible to organize whole rooms through the plan module from 3.6 m to 4.2 m, that decides the floor plan of a wooden house.

A study on the implementation and performance evaluation of low-power ZigBee sensor in the M2M gateway system (M2M Gateway 시스템을 위한 저전력 지그비 센서 구현 및 성능평가에 관한 연구)

  • Jeon, Joong-Sung;Kim, Nam-Hwan
    • Journal of Advanced Marine Engineering and Technology
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    • v.40 no.7
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    • pp.629-634
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    • 2016
  • This paper describes the implementation of a ZigBee sensor node that can be utilized as a multiband and machine to machine (M2M) communication gateway. The IEEE 802.15.4-2003 standard was used as the wireless network frequency band. Ember's Type EM357 SoC was used as the transmission and reception device to perform the communication function, and it was also used for both the main M2M gateway and the sensor node. For the implementation of the operating protocol, EmberZNet Stack 4.5.4 from the Ember Corporation was used. The measurement of the reception sensitivity in the receiving module and the actual output signal from the reference were obtained from the transmission of a packet, and the packet included the M2M gateway within the attached ZigBee sensor. The packet error rate was measured as 0% with a -98 dBm reception sensitivity at the ZigBee frequency. In addition, excellent current characteristics of the ZigBee modules were shown by the implementation of the low-power circuit.

Control Variables of Remote Joint Analysis Realization on the M2M Case

  • Lim, Sung-Ryel;Choi, Bo-Yun;Lee, Hong-Chul
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.6 no.1
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    • pp.98-115
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    • 2012
  • New trend called ubiquitous leads the recent business by standardization and integration. It should be the main issue how to guarantee the integration and accountability on each business, especially in mission critical system which is mainly supported by M2M (Machine to Machine) control mechanism. This study is from the analysis of digital forensics case study that is from the M2M Sensing Control Mechanism problem of the "Imjin River" case in 2009, where a group of family is swept away to death by water due to M2M control error. The ubiquitous surroundings bring the changes in the field of criminal investigation to real time controls such as M2M systems. The needs of digital forensics on M2M control are increasing on every crime scene but we suffer from the lack of control metrics to get this done efficiently. The court asks for more accurately analyzed results accounting high quality product development design. Investigators in the crime scene need real-time analysis against the crime caused by poor quality of mission critical systems. It seems to be every need of Real-Time-Enterprise, so called ubiquitous society on the case. We try to find the efficiency and productivity in discovering non-functional design defects in M2M convergence products focusing on three metrics in study model with quick implementation. Digital forensics system in present status depends on know-how of each investigator and is hard to expect professional analysis on every field. This study set up a hypothesis "Co-working of professional investigators on each field will qualify Performance and Integrity" especially in mission critical system such as M2M and suggests "Online co-work analysis model" to efficiently detect and prevent mission critical errors in advance. At the conclusion, this study proved the statistical research that was surveyed by digital forensics specialists around M2M crime scene cases with quick implementation of dash board.

Preparation and Physical Properties of Aqueous Polyurethane Based on Mono Methyl Ether for Skin Layer Coating (Skin layer 코팅에 사용되는 Mono Methyl Ether 기반 수성 폴리우레탄의 제조 및 물리적 성질)

  • Lee, Joo-Youb
    • Journal of the Korean Applied Science and Technology
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    • v.36 no.2
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    • pp.524-530
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    • 2019
  • In this study, polyether polyol polypropylene glycol and isophorone diisocyanate (IPDI) were synthesized based on polyrupopylene mono methyl eher (PM) for the synthesis of water - soluble polyurethane for coating on leather skin layer. After synthesis of prepolymer, PM was added at $40^{\circ}C$ to 1M, 2M, 3M, and 4M to inhibit the viscosity rise, and neutralization reaction and chain extension reaction were carried out to prepare polyurethane samples. According to the measurement results of the tensile strength, elongation and adhesive strength of the prepared sample, the tensile strength was 2.109 kgf / mm2 for PM 1M, 1.721kgf / mm2 for 4M, elongation was 496% for PM 1M, 522% for 4M, adhesion was 1.114 kgf / cm for PM 1M and 0.99 kgf / cm for 4M.