• Title/Summary/Keyword: MYO7A

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Predicting User Profile based on user behaviors (모바일 사용자 행태 기반 프로파일 예측)

  • Sim, Myo-Seop;Lim, Heui-Seok
    • Journal of the Korea Convergence Society
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    • v.11 no.7
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    • pp.1-7
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    • 2020
  • As the performance of mobile devices has dramatically improved, users can perform many tasks in a mobile environment. This means that the use of behavior information stored in the mobile device can tell a lot of users. For example, a user's text message and frequently used application information (behavioral information) can be utilized to create useful information, such as whether the user is interested in parenting(profile prediction). In this study, I investigate the behavior information of the user that can be collected in the mobile device and propose the item that can profile the user. And I also suggest ideas about how to utilize profiling information.

A Study of the Housewives' Perception Level on Wedding Food in Busan & Kyungnam Area (부산.경남 지역 주부들의 전통혼례음식 인식 정도에 관한 연구)

  • Kim, Kyoung-Myo;Cho, Yong-Bum
    • Culinary science and hospitality research
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    • v.13 no.2
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    • pp.136-152
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    • 2007
  • This study was carried out to survey the degree of the perception and necessity of wedding food prepared by housewives. The participants of the survey were 331 housewives lived in Busan and Kyungnam area. The findings could be summarized as follows: The housewives lived in Busan and Kyungnam area had evaluated the necessity of wedding foods, Paebaek foods or Yedan foods. The respondents of 36.6% answered that they will order wedding foods from specialists, whereas 28.7% said that they will prepare them by themselves. More than half of the respondents(56.2%) thought that current wedding foods were prodigal and have to be done in thrifty manner. Broadly 46.8% of the respondents considered that the ritual practices of wedding foods will decrease steadily. A conclusion was that lots of participants had a negative view of wedding foods and pointed out the necessity of developing them to reflect traditional wedding customs with economic costs.

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Chemical Constituents from Aegle marmelos Fruits

  • Kim, Hye Jin;Seo, Young Ju;Htwe, Khin Myo;Yoon, Kee Dong
    • Natural Product Sciences
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    • v.27 no.4
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    • pp.240-244
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    • 2021
  • Aegle marmelos (Rutaceae) is a deciduous shrub or tree and typically known as bael throughout Southeast Asia and has been used as a medicinal plant and a food ingredient. In this study eight compounds were determined to be O-(3,3-dimethylallyl) halfordinol (1), (R)-aegeline (2), (R)-marmeline (3), imperatorin (4), xanthotoxol (5), valencic acid (6), vanillic acid (7) and rutin (8). The chemical structures of the isolates were elucidated through spectroscopic evidence including 1D, 2D NMR, ESI-Q-TOF-MS and optical rotation.

The Study of Asphalt Concrete Mixture Design Using Maximum Density Theory (최대밀도이론을 이용한 아스팔트 혼합물의 배합설계에 관한 연구)

  • Lee, Seung-Han;Park, Hyun-Myo;Jung, Yong-Wook;Jang, Seck-Soo;Kim, Jang-Wook
    • Proceedings of the Korea Concrete Institute Conference
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    • 2005.05b
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    • pp.525-528
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    • 2005
  • This study determines the best composite grade to minimize the void of aggregate mixture based on the maximum density theory in an attempt to suggest a mix proportion method design for asphalt mixtures. Study results show that the grading curve with the maximum mass per unit capacity of each aggregate mixture satisfied the KS standards and the optimum AP content to meet the optimal asphalt mixture void rate of 4$\%$ was 5.7$\%$, less than the optimum AP content of 6.5$\%$ suggested in the Marshal mix proportion method design. At the same time, the asphalt mixture produced based upon the suggested mix proportion method had a flow value 17$\%$ lower than that of asphalt mixture produced according to the Marshal method, while its density was greater by 0.06$\~$0.09. This suggests that the introduced mix proportion method design helps to improve the shape flexibility and crack-resistance of asphalt concrete.

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Isolation and identification of goose skeletal muscle satellite cells and preliminary study on the function of C1q and tumor necrosis factor-related protein 3 gene

  • Wang, Han;He, Ke;Zeng, Xuehua;Zhou, Xiaolong;Yan, Feifei;Yang, Songbai;Zhao, Ayong
    • Animal Bioscience
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    • v.34 no.6
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    • pp.1078-1087
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    • 2021
  • Objective: Skeletal muscle satellite cells (SMSCs) are significant for the growth, regeneration, and maintenance of skeletal muscle after birth. However, currently, few studies have been performed on the isolation, culture and inducing differentiation of goose muscle satellite cells. Previous studies have shown that C1q and tumor necrosis factor-related protein 3 (CTRP3) participated in the process of muscle growth and development, but its role in the goose skeletal muscle development is not yet clear. This study aimed to isolate, culture, and identify the goose SMSCs in vitro. Additionally, to explore the function of CTRP3 in goose SMSCs. Methods: Goose SMSCs were isolated using 0.25% trypsin from leg muscle (LM) of 15 to 20 day fertilized goose eggs. Cell differentiation was induced by transferring the cells to differentiation medium with 2% horse serum and 1% penicillin streptomycin. Immunofluorescence staining of Desmin and Pax7 was used to identify goose SMSCs. Quantitative realtime polymerase chain reaction and western blot were applied to explore developmental expression profile of CTRP3 in LM and the regulation of CTRP3 on myosin heavy chains (MyHC), myogenin (MyoG) expression and Notch signaling pathway related genes expression. Results: The goose SMSCs were successfully isolated and cultured. The expression of Pax7 and Desmin were observed in the isolated cells. The expression of CTRP3 decreased significantly during leg muscle development. Overexpression of CTRP3 could enhance the expression of two myogenic differentiation marker genes, MyHC and MyoG. But knockdown of CTRP3 suppressed their expression. Furthermore, CTRP3 could repress the mRNA level of Notch signaling pathway-related genes, notch receptor 1, notch receptor 2 and hairy/enhancer-of-split related with YRPW motif 1, which previously showed a negative regulation in myoblast differentiation. Conclusion: These findings provide a useful cell model for the future research on goose muscle development and suggest that CTRP3 may play an essential role in skeletal muscle growth of goose.

PREPARATION AND PHARMACOKINETICS OF METHOTREXATE DELIVERY SYSTEM USING LONG-CIRCULATING LIPOSOMES

  • Hong, Myo-Sook;Kim, Chong-Kook
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1996.04a
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    • pp.287-287
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    • 1996
  • Long-circulating liposomes have prompted interests in using them as a drug delivery system. This improvements in delivery has been thought to be the results from sustained action of liposomes in plasma without RES uptake. Although methotrexate(MTX) has been one of the most widely used antineoplastc drug, its use was limited by prompt RES uptake. The purpose of this study was to prepare long-circulating liposomes for MTX using highly water-soluble polymer (PEG-PE). In vitro, release of MTX from liposomes in phosphate buffer (pH 7.4), rat liver homogenate, and rat plasma was investigated. The pharmacokinetics and organ distribution of fee drug, conventional and long-circulating liposomes were also compared with one another after intravenous administration to rats.

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A Novel Method to Reduce Crest Factor of Electronic Ballast for Fluorescent Lamps Using Pulse Frequency Modulation (펄스 주파수 변조 기법을 이용한 형광등 안정기의 파고율 저감 기법)

  • Song, Joo-Ho;Lee, Dong-Yun;Song, Joong-Ho;Choi, Ju-Yeop;Choy, Ick;Lim, Myo-Taeg
    • The Transactions of the Korean Institute of Power Electronics
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    • v.5 no.3
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    • pp.291-299
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    • 2000
  • 형광등의 수명은 형광등 안정기의 시동 시나리오와 형광등 전류의 파고율에 영향을 받는다. 본 논문에서는 특히 파고율을 주로 다루며, 파고율을 줄이기 위한 새로운 방법을 제시하고자 한다. 제안하고자 하는 방법은 펄스 주파수 변조기법(Pulse Frequency Modulation, PFM)을 이용하며, PFC(Power Factor Correction)가 만드는 50% 벨리필 전압 파형을 PFM 제어 신호로 사용한다. 본 논문에서는 제안하는 PFM 제어 기법으로 파고율을 1.7 이하로 낮출 수 있음을 모의 실험과 실험을 통해 확인하여, 제안한 기법의 타당성을 검증한다.

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Anti-inflammatory Activities of Coumarins Isolated from Angelica gigas Nakai on LPS-stimulated RAW 264.7 Cells

  • Ma, Yong-Fen;Jung, Jae-Yeon;Jung, Yu-Jung;Choi, Ji-Hye;Jeong, Woo-Sik;Song, Young-Sun;Kang, Jae-Seon;Bi, Kaishun;Kim, Myo-Jeong
    • Preventive Nutrition and Food Science
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    • v.14 no.3
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    • pp.179-187
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    • 2009
  • Five kinds of coumarin compounds were successfully purified from Angelica gigas Nakai by using recyclingpreparative HPLC and identified as decursin (1), decursinol angelate (2), 7-demethylsuberosine (3), marmesin (4), and decursinol (5) by NMR analyses. None of the purified compounds in ethanol showed DPPH radical scavenging activity, while the A. gigas extract (AGNEX) displayed a significant level of activity. Interestingly, compounds 3 in phosphate buffered saline (PBS) showed good $ABTS^+$ radical scavenging activity ($IC_{50}=8.1{\mu}g$/mL) as did compounds 4 and 5. The anti-inflammatory activities of the purified compounds were evaluated and compared using the NO concentration assay and western blot analysis on LPS-stimulated RAW 264.7 cells. NO production was significantly suppressed by all the compounds in a dose-dependent manner among which compounds 1, 2, and 3 showed very good activities with $IC_{50}$ values of 7.4, 6.5, and $7.6{\mu}g$/mL, respectively. Treatment with compounds 1-5 effectively suppressed the expression levels of iNOS, IL-1$\beta$, and COX-2, which are responsible for promoting the inflammatory process. Thus, the ethanol extract and coumarin compounds of A. gigas Nakai hold promise for use as potential anti-inflammatory agents.

The Effect of a Disaster Nursing Convergence Education Program on Disaster Nursing Knowledge, Preparedness and Self-Confidence of Nursing Students (재난간호 융합교육프로그램이 간호학생의 재난간호 지식, 준비도 및 자신감에 미치는 효과)

  • Jung, Hyang-Mi;Kim, Nam-Hee;Lee, Yoen Hee;Kim, Myo Sung;Kim, Myung Ja
    • Journal of the Korea Convergence Society
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    • v.9 no.1
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    • pp.377-386
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    • 2018
  • The purpose of this study was conducted to identify the effect of a disaster nursing convergence education program on disaster knowledge, preparedness, and self-confidence. A quasi-experimental was conducted using nonequivalent control group pretest posttest design. The subjects were senior grade nursing students who were in B metropolitan city. The education program was provided using disaster management, disaster nursing practice, disaster psychosocial support. The experimental group was participated on program 56 hours during 2 weeks, from June 26 to July 7, 2017. The experimental group showed significant differences in disaster nursing knowledge(F=81.41, p<.001), preparedness(F=110.62, p<.001) and self-confidence(t=7.27, p<.001). Therefore this convegence program could be a good extra-curriculum and it is necessary to develop more variable contents.

Liver tissue sensor for the determination of dopamine (간조직 센서를 이용한 dopamine의 정량)

  • Hur, Moon-Hye;Kim, Ki-Myo;Kim, Young-Hak;Paek, Kwang-Jin;Choi, Hyun-Young;Ahn, Moon-Kyu
    • Analytical Science and Technology
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    • v.8 no.3
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    • pp.365-370
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    • 1995
  • A tissue biosensor for the measurement of dopamine has been constructed by immobilizing the slice of Sprague-Dawley rat liver on $NH_3$-sensing electrode. To overcome the defect of tissue sensors, the maximal velocity of response curve was measured and applied to the Lineweaver-Burk equation instead of the Nernst equation. And then compared the results with those obtained from Nernst equation. When we obtained calibration curves from Nernst equation, there were variances on the slope and the linear range. But from Lineweaver-Burk equation, the scale of variance was small. Response time was reduced from 7~12 minutes to 2~3 minutes.

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