• Journal of Life Science
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• v.32 no.7
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• pp.567-577
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• 2022

Recently, the prevalence of ischemic diseases, such as ischemic heart disease, cerebral ischemia, and peripheral arterial disease, has been continuously increasing due to the aging population. The current standardized treatment for ischemic diseases is reperfusion therapy through pharmacotherapy and surgical approaches. Although reperfusion therapy may restore the function of damaged arteries, it is not effective at restoring the function of the surrounding tissues that have been damaged due to ischemia. Therefore, it is necessary to develop a new treatment strategy that can safely and effectively treat ischemic damage and restore the function of surrounding tissues. To overcome these limitations, stem cell-based therapy to regenerate the damaged region has been studied as a promising strategy for ischemic vascular diseases. Mesenchymal stem cells (MSCs) can be isolated from diverse tissues and have been shown to be promising for the treatment of ischemic disease by regenerating damaged tissues through immunomodulation, the promotion of angiogenesis, and the secretion of various relevant factors. Moreover, new approaches to enhancing MSC function, such as cell priming or enhancing transplantation efficiency using a 3D culture method, have been studied to increase stem cell therapeutic efficacy. In this review, we provide various strategies by which MSCs are used to treat ischemic diseases, and we discuss the challenges of MSC transplantation, such as the differentiation, proliferation, and engraftment of MSCs at the ischemic site.

• The Journal of the Korea institute of electronic communication sciences
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• v.3 no.1
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• pp.19-25
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• 2008

In order to realize future ubiquitous, it needs to establish an environment witch service is provided to an user without user's awareness. This study suggests the mobile context awareness algorithm for that. With DB collected using LBS technology, it aims to recognize service status of a terminal and to maximize user's convenience by offering service through continuous inter-operability for various demand and environment of users against the status of a terminal. To realize the algorithm, it adds a terminal status deduction process to MSC. And then, it suggests the algorithm witch determines terminal status depending on status parameter defined by analyzing LBS-based short information by MSC. It realize C code.

• Proceedings of the KSME Conference
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• 2001.06c
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• pp.507-512
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• 2001

In this work, tool holder system has been designed and builted to measure cutting forces in diamond turning. This system design includes a 3-component piezo-electric tranducer. Initial experiments with tool holder system included verification of its predicted dynamic characteristics as well as a detailed study of cutting parameters. Tool holder system is modeled by considering the element dividing, material properties, and boundary conditions using MSC/PATRAN. Mode and frequency analysis of structure is simulated by MSC/NASTRAN, for the purpose of developing the effective design. Many cutting experiments have been conducted on 6061-T6 aluminum. Tests have involved investigation of velocity effects, and the effects of depth and feedrate on tool force. Forces generally increase with increasing depth of cut. Increasing feedrate does not necessarily lead to higher forces.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.36 no.12
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• pp.1229-1235
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• 2008

ELT(emergency locator transmitter) has assisted in the rescue of thousands of lives in distress. Aviators, mariners and land users being equipped with distress beacons are capable of transmitting distress signals to the satellites in emergency situations anywhere in the world. In this paper, Drop/Impact simulation was performed for ELT Body-case. FE model for Body-case was constructed with MSC/Dytran and refined using the Karas example simulation for Body-case prototype. Shock/impact survivability analysis was performed for ELT operations. FE model constructed with MSC/Nastran. Transient response analysis for refined ELT model was perfomed for ELT under impact shock loading condition.

• Proceedings of the KSRS Conference
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• 2005.10a
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• pp.620-623
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• 2005

KARI has prepared Calibration and Validation activities for the KOMPSAT-2 (KOrea Multi-Purpose SATellite-2) MSC data that will be launched at the end of this year. Firstly, we divided the Cal/Val activities of it to four parts, Spatial, Spectral, Radiometric and Geometric, and defmed the detailed Cal/Val items from them. Secondly, Cal/Val targets have been defined and manufactured for the role of them. Thirdly, we have made the plan and the procedure for the Cal/Val items, developed the codes for them, studied more detailed method to do them, and trained the Cal/Val activities using the foreign satellite image data by ourselves. KARI has been now setting up the KOMPSAT-2 LEOP plan with the Cal/Val activities, and probably will finish the EOP Cal/Val activities for the KOMPSAT-2 MSC data by the next April or May.

• Journal of Powder Materials
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• v.21 no.1
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• pp.7-15
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• 2014

This study investigated the densification behavior of rhenium alloys including W-25 wt.%Re and Re-2W-1Ta (pure Re) during sintering. The dilatometry experiments were carried out to obtain the in-situ shrinkage in $H_2$ atmosphere. The measured data was analyzed through shrinkage, strain rate and relative density, and then symmetrically treated to construct the linearized form of master sintering curve (MSC) and MSC as a well-known and straightforward approach to describe the densification behavior during sintering. The densification behaviors for each material were analyzed in many respects including apparent activation energy, densification parameter, and densification ratio. MSC with a minimal set of preliminary experiments can make the densification behavior to be characterized and predicted as well as provide guideline to sinter cycle design. Considering the results of linearized form and MSC, it was confirmed that the W-25 wt.%Re compared to Pure Re is more easily densified at the relatively low temperature.

• Proceedings of the KSRS Conference
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• 2004.10a
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• pp.436-439
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• 2004

Output data streams of the MSC contain flags, Headers and image data according to the established protocols and data formats. Especially the Header added to each data lines contain information of a line sync, a line counter and, ancillary data which consist of ancillary identification bit and one ancillary data byte. This information is used by ground station to calculate the geographic coordinates of the image and get the on-board time and several EOS(Electro-Optical Subsystem) parameters used at the time of imaging. Therefore, the EGSE(Electrical Ground Supporting Equipment) that is used for testing MSC has to have functions of interpreting and displaying this Header information correctly following the protocols. This paper describes the design of the header data processing module which is in EOS­EGSE. This module provides users with various test functions such as header validation, ancillary block validation, line-counter and In-line counter validation checks which allow convenient and fast test on imagery data.

• Proceedings of the KSRS Conference
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• v.1
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• pp.372-375
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• 2006

The MSC is a high resolution multi-spectral camera system which is mounted on the KOMPSAT-II satellite. The electro-optic camera system has a refocusing mechanism which can be used in-orbit by ground commands. By adjusting locations of some elements in optics, the system can be focused precisely. The focus mechanism in MSC is implemented with stepper motor and potentiometer. By reading the value of the potentiometer, rough position of the motor can be understood. The exact location of the motor can not be acquired because the information from the potentiometer can not be so accurate. However, before and after certain events of the satellite, like a satellite launch, the direction of the movement or order of the magnitude of the movement can be understood. In this paper, the trend analysis of the focus motor position during the ground test phase is introduced. This result can be used as basic information for the focus calibration after launch. By studying the long term trend, deviation from the best focal point can be understood. The positions of the focus motors after launch are also compared.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.39 no.12
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• pp.1150-1159
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• 2011

Reliability is defined as a probability that a system will operate properly for a specified period of time under the design operating conditions without failure. Reliability-Redundancy Optimization Problem(RROP) involves selection of components with multiple choices, redundancy levels and redundancy strategy(Active or Standby) for maximizing system reliability with constraints such as cost, weight, etc. Based on the design configuration of Multi-Spectral Camera(MSC) system of KOMPSAT-2, the mathematical programming model for RROP is suggested in this study. Due to the nature of RROP, i.e. NP-hard problem, Parallel Particle Swarm Optimization(PPSO) algorithm is proposed to solve it. The result of the numerical experiment for RROP is presented as instance of recommended design configuration at some mission time.

• Proceedings of the Korean Society For Composite Materials Conference
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• 2003.10a
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• pp.132-136
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• 2003

A Multi-Spectral Camera (MSC) is the payload of KOMPSAT-2 which is designed for earth imaging in visible and near-Infrared region on a sun-synchronous orbit. The telescope in the MSC is a Ritchey-Chretien type with large aperture. The telescope structure should be well stabilized and the optical alignment should be kept steady so that best images can be achieved. However, the MSC is exposed to adverse thermal environment on the orbit which can give impacts on optical performance. Metering structure which is exposed to adverse space environment should have tight requirement of low thermal expansion and hygroscopic stability. In order to meet those stability requirements in addition to fundamental structural ones telescope structure was designed with newly developed graphite-cyanate composite which has high tensile modulus, high thermal conductivity and low moisture absorption compared with conventional graphite-epoxy composite. In this paper, space-borne telescope structure with new composite material will be presented and fulfillment of stability requirements will be verified with designed structure.