• Journal of mucopolysaccharidosis and rare diseases
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• v.2 no.1
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• pp.19-22
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• 2016

Purpose: Mucolipidosis type II (ML II), also known as I-cell disease is an autosomal recessive inherited disorder of lysosomal enzyme transport caused by a deficiency of the uridine diphosphate (UDP)-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (GlcNAc-phosphotransferase). Clinical manifestations are skeletal abnormalities, mental retardation, cardiac disease, and respiratory complications. A severely and rapidity progressive clinical course leads to death before 10 years of age. Methods/Results: In this study we diagnosed three cases of prenatal ML II in two different at-risk families. We compared two procedures -biochemical analysis and molecular analysis - for the prenatal diagnosis of ML II. Both methods require an invasive procedure to obtain specimens for the diagnosis. Biochemical analysis requires obtaining cell cultures from amniotic fluid for more than two weeks, and would result in a late diagnosis at 19 to 22 weeks of gestation. Molecular genetic testing by direct sequence analysis is usually possible when mutations are confirmed in the proband. Molecular analysis has an advantage in that it can be performed during the first-trimester. Conclusion: Molecular diagnosis is a preferable method when a prompt decision is necessary.

• The Journal of Information Systems
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• v.12 no.2
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• pp.129-149
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• 2003

One of the important applications in Enterprise Resource Planning(ERP) systems is the Manufacturing Resource Planning(MRPII) system using Bill of Material(BOM). The manufacturing resource planning determines the quantity and timing of the production or purchase of subassemblies and raw materials needed to support the Master Production Scheduling(MPS). The bill of material is the recipe, a list of the materials needed to make a product. This paper intends to suggest a component-based materials management system using Unified Modeling Language(UML), as an application system for automobile part industry. Applying component based materials management systems designed with UML methodology, we analyzed the workflow and the document on materials management process from production planning to inventory management, and implemented a prototype of efficient materials management system, as a surrogate of existing material requirement planning(MRPI) system. To produce many other assemblies for a automobile part firm, component parts are assembled into subassemblies that are joined to assemble the finished product. Through the system suggested in this study, the level of inventory has cut down and the cost of inventory management has decreased. Also, the development method using UML makes the analysis and design phase to shorten in implementation period of MRPII system. The implementation of materials management system using CBD shows the ease of use in software reuse and the interoperability with corporate Internal information system. The result of applying object-oriented CBD technique is to minimize the risk of life cycle and facilitate the reuse of software as mentioned to limitation of information engineering methodology.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.19 no.3
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• pp.29-44
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• 2016

The purpose of this study is to quantitatively and visually analyze the degree of green biotope fragmentation caused by road construction and other development work using FRAGSTATS and GUIDOS tool. Moreover, linking of the endangered species research, we mapped "Biotope Fragmentation Map" of Daejeon-city. The findings of the study are summarized as follows: First, as the result of FRAGSTATS, landscape indices : number of patch(NP), mean patch size (MPS), edge length(TE), mean nearest neighbor distance(MNN), edge shape(LSI) showed meaningful change from fragmentation. Moreover, the result of GUIDOS analysis, middle core-small core-bridge-branch-edge-islet-perforation showed increase of area percentage without large core. Lastly, analysis result of 'Biotope Fragmentation Map' revealed that changing site of large core's size appeared eighteen-site and designated as the special protection area appeared forty-one site. As the result of the two data, overlapping areas that showed both change of core size and revealed special protection areas revealed four site. For example, five species of endangered species appeared on the NO. 4 site in 'Biotope Fragmentation Map'. The findings of this study as summarized above are considered to play an important role in basic data preventing green biotope fragmentation at the planned level from various development work.

• Journal of the Korean Institute of Navigation
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• v.5 no.2
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• pp.49-58
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• 1981

One of the main purposes of the marine gyrocompass follow-up system is to preserve the sensitive part from the wandering error due to the frictional or torsional torque around the vertical axis. This error can be diminished through the rapid follow-up action, which minimizes the relative azimuthal angular displacement between the sensitive and follow-up parts and shortens the duration of the same displacement. But an excessive rapidity of the follow-up action would result in a sustained oscillation to the system. Therefore, to design a new type of the follow-up system, the theoretical annlysis of the problems concerned should be studied systematically by introducing the control theory. This paper suggest a concrete procedure for the optimal adjustment of the gyrocompass follow-up system, utilizing the mathematic model and the stability informations formerly investiaged by the author. For theoptimal determination of the adjustable paramfter K, the performance index(P.I.), ITSE(Intergral of the Time multiplied by the Squared Error) is proposed, namely, P.I. = $\int_{0}^{\infty} t \cdot e^{2}(t)dt$ where t is time and e(t) means control error. Then, the optimal parameter minimizing the performance index is calculated by means of Parseval's theorem and numerical computation, and the validity of the obtained optimal value of the parameter Ka is examined and confirmed through the simulations and experiments. By using, the proposed method, the optimal adjustment can be performed deterministically. But, this can not be expected in the conventional frequency domain analysis. While the Mps of the original system vary to the extent of from 0.98 to 46.27, Mp of the optimal system is evaluated as 1.1 which satisfies the generally accepted frequency domain specification.

• Proceedings of the KIEE Conference
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• 2005.07b
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• pp.1228-1230
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• 2005

This paper deals with design of heater trigger switching in a persistent current system(PCS) by finite element method(FEM) analysis of YBCO coated conductor(CC) tape. Most promising superconducting wire is YBCO coated conductor tape in these days for its high n value and critical current independency from external magnetic field. It is expected to be used many superconducting application such as fault current limiter and cable etc. The superconducting magnet which is operated in persistent current mode in SMES, NMR, MRI and MAGLEV has many advantages such as a high uniformity of a magnetic field and reducing a thermal loss. A PCS system consists of magnet power supply (MPS) which energized current to a magnet, heater, a coated conductor tape for switching, and superconducting magnet. In this paper, the characteristic of thermal quench of the YBCO CC tape and BSCCO tape by heater trigger analyzed by FEM. And optimal length of heater is calculated by temperature and time analysis. This heater trigger analysis is expected to be a basic concept of PCS application design.

• The Journal of Dong Guk Oriental Medicine
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• v.8 no.2
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• pp.47-67
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• 2000

The purpose of this study is to assess the usefulness of thermography in patients with musculoskeletal disease. Thermography is noninvasive, easy to reading, objective and physiologic instrument by measuring and imaging infrared energy emitted from skin surface. Thermography can show the skin temperature changes in various conditions of the body with musculoskeletal disease. This literature review was done for the usefulness of thermography in diagnosing musculoskeletal disease. In conclusion, thermography was adapted in radiculopathy, MPS, peripheral neuropathy, RSD, Raynaud's phenomen, TMJ dysfunction, etc. It was useful as a secondary diagnostic method in those diseases, also possible as a primary diagnostic method in RSD, Raynaud's phenomen. And, it might be reliable tool for estimating disease procedure and consequence after treatment. But, the objectivity of the reading and the development of the operating method are required for further adaptation in musculoskeletal disease.