• Journal of the Korean Mathematical Society
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• v.56 no.3
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• pp.805-823
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• 2019

We introduce polynomial PH-MPH transitive mappings which transform planar PH curves to MPH curves in ${\mathbb{R}}^{2,1}$, and prove that parameterizations of Enneper surfaces of the 1st and the 2nd kind and conjugates of Enneper surfaces of the 2nd kind are PH-MPH transitive. We show how to solve $C^1$ Hermite interpolation problems in ${\mathbb{R}}^{2,1}$, for an admissible $C^1$ Hermite data-set, by using the parametrization of Enneper surfaces of the 1st kind. We also show that we can obtain interpolants for at least some inadmissible data-sets by using MPH biarcs on Enneper surfaces of the 1st kind.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.34 no.2
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• pp.125-132
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• 2023

Objectives: This study investigated the relationship between suicidal behavior and the use of methylphenidate (MPH) or atomoxetine (ATX) in patients with attention deficit hyperactivity disorder (ADHD). Methods: The Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines were used to conduct a meta-analysis. The Physiotherapy Evidence Database scale was used to score the quality of the studies. Results: Nine studies were included in this quantitative analysis. The analysis included 602864 patients with ADHD (521125 and 81739 patients were taking methylphenidate [MPH group] and atomoxetine [ATX group], respectively) and 19230 healthy controls. The overall estimates were in the order of the control, MPH, and ATX groups; however, no statistically significant between-group difference was observed in the incidence of events (p=0.553 for control vs. MPH; p=1.000 for control vs. ATX; p=1.000 for MPH vs. ATX). Conclusion: The rate of suicidal behavior was higher in the ADHD groups treated with MPH and ATX than in the control group. However, no statistically significant difference was observed between the ADHD groups treated with MPH and ATX, and the control group. Therefore, MPH and ATX did not increase suicidal behavior.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.16 no.2
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• pp.279-285
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• 2005

Objectives : This study was performed to evaluate the efficacy and safety of MPH-OROS and parental satisfaction for treatment of children with ADHD Method : The 569 participants were clinically diagnosed for ADHD using DSM-IV criteria. We switched current medication to MPH-OROS or introduced MPH-OROS for treatment of ADHD. We assessed the clinical global impression severity of illness (CGI-S), the clinical global impression severity of improvement(CGI-I). And the parents of participants measured the Korean version of Conners rating scale at baseline, the 1 st week and the 3rd week after MPH-OROS trial. At the 3rd week, the parents measured the parent satisfaction questionnaire. Results : $13\%$ of participants dropped out because of several causes including side effects. The change of CGI-S was significantly decreased. Using CGI-I, the improvement was $72.3\%$ at the 1st week and $87.4\%$ at the 3rd week. The total score of the Korean version of Conners parent rating scale was significantly decreased. The participants complaining one or more of side effects were 119$(20.7\%)$, and the most common side effect was anorexia. The $94\%$ of parents replied that they were overall satisfied with MPH-OROS trial. Also the advantages of MPH-OROS of parental report were the long duration of the drug, the improvement of schoolwork and attitude, the improvement of home behavior and homework and the improvement of overactivity. Conclusion : MPH-OROS is effective and well-tolerated in actual clinical use for ADHD.

• Journal of applied mathematics & informatics
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• v.26 no.1_2
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• pp.121-133
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• 2008

In this article, we define Minkowski Pythagorean-hodograph (MPH) curves in the Minkowski plane $\mathbb{R}^{1,1}$ and obtain $C^1$ Hermite interpolations for MPH quintics in the Minkowski plane $\mathbb{R}^{1,1}$. We also have the envelope curves of MPH curves, and make surfaces of revolution with exact rational offsets. In addition, we present an example of $C^1$ Hermite interpolations for MPH rational curves in $\mathbb{R}^{2,1}$ from those in $\mathbb{R}^{1,1}$ and a suitable MPH preserving mapping.

• YAKHAK HOEJI
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• v.41 no.3
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• pp.359-364
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• 1997

Resistance gene mphK was cloned from Escherichia coli 209K strain which is highly resistant to erythromycin (EM). By using the cloned plasmid pGE64, E. coli NM522 was transformed. The comparison of macrolide-phosphotransferase K [MPH(K)] activity between E. coli 209K and E. coli NM522(pGE64) showed that the total enzyme activity of MN522(pGE64) was fifty-fole higher than that of 209K. To identify characteristics of MPH(K) more precisely. MPH(K) was isolated and purified from the NM522 (pGE64). The final purification f MPH(K) through several stages of purification process was 89 fole and the overall recovery was 11%. This enzyme was monomer with the molecular weight of 34 kDa and its isoelectric point (pI) was 5.0. The optimal pH and temperature for activity were 8.0 and $40^{\circ}C$, respectively.

• Journal of Adhesion and Interface
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• v.9 no.3
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• pp.1-6
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• 2008

Hard coatings were deposited on a polycarbonate plate as potential substitutes for glass in cars. In this research the copolymers of p-polyphenylene (PPH) and m-phenylene (MPH) were synthesized, and using these copolymers the coatings were conducted on a polycarbonate plate. The hardness of the coating surface was affected with the mole ratio of PPH and MPH in the copolymer. When the mole ratio of PPH : MPH in the copolymer was 20 : 80, the coating showed 2H class of pencil hardness and also showed the best abrasion resistance.

• Food Science and Preservation
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• v.24 no.7
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• pp.1007-1016
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• 2017

Melania snail (Semisulcospira libertina) was traditionally used as the healthy food in Korea. It was generally known to improve liver function and heal a diabetes. The aim of this study was to elucidate the anti-diabetic mechanism of melanian snail hydrolysates treated with protamex (MPH) by investigating the inhibitory action on protein tyrosine phosphatase 1B (PTP1B), the improving effect on the insulin resistance in C2C12 myoblast and the protective effect for pancreatic beta-cell (INS-1) under the glucose toxicity. The melania snail hydrolysates treated with protamex (MPH), which showed the highest degree of hydrolysis (43%), and inhibited effectively PTP1B activity ($IC_{50}=15.42{\pm}1.1{\mu}g/mL$), of which inhibitory effect was higher than usolic acid, positive control ($IC_{50}=16.65{\mu}g/mL$). MPH increased the glucose uptake in C2C12 myoblast treated with palmitic acid. In addition, MPH increased insulin mRNA expression level by over 160% with enhanced cell viability in INS-1 cell under the high glucose concentration (30 mM). These results suggest that MHP may improve the diabetic symptom by the inhibiting the PTP1B activity, increasing the glucose uptake in muscle cell and protecting the pancreatic beta-cell from glucose toxicity.

• Journal of applied mathematics & informatics
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• v.28 no.1_2
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• pp.131-141
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• 2010

In this paper, we propose a new method to obtain $C^1$ MPH quartic Hermite interpolants generically for any $C^1$ Hermite data, by using the speed raparametrization method introduced in [16]. We show that, by this method, without extraordinary processes ($C^{\frac{1}{2}}$ Hermite interpolation introduced in [13]) for non-admissible cases, we are always able to find $C^1$ Hermite interpolants for any $C^1$ Hermite data generically, whether it is admissible or not.

• Journal of Korean Port Research
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• v.13 no.1
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• pp.113-122
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• 1999

Congestion and traffic accidents occur on the merge and diverge sections in the interchange of the freeway. Studies have been conducted to reduce the traffic delay and accidents on the merge section in the freeway since 1960s. but a study was not conducted to estimate the speed variation on the merge section construct models estimated for the speed variation and suggest the appropriate measures. The purpose of this study was to identify the traffic flow characteristics on the merge section in the freeway construct the models estimated for the speed variation on the merge section in the freeway and finally establish the appropriate measure for reduction of traffic delay and accidents on the merge section in the freeway. The following results were obtained: I) Speed variations in the urban freeway appeared to be about 3.2mph, 6.5mph and 7.4mph based on the morning peak period, afternoon peak period and 24-hours period but those in the suburban freeway appeared to be about 8.0mph, 11.1mph and 10.1mph based on the same periods respectively. So different speed reduction signs need be installed to reduce delay and accidents on the merge section in the freeway based on the areas and periods as the freeway traffic management system(FTMS). ii) These models estimated for speed variation need to be studied with the changeable message sign(CMS) technique based on the real-time data so that the traffic flow could be maximized and the traffic delay and accidents be on the merge section in the freeway as more efficient freeway traffic management system(FTMS) in the near future.

• The Journal of Pediatrics of Korean Medicine
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• v.24 no.2
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• pp.147-158
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• 2010

Objectives The study was designed to find out the relationships between low weight and growth, skeletal maturity among children by analyzing body composition and bone age. Methods Subjects were composed of 336 children from six years to seventeen years of age, without any other diseases related to growth, who visited the department of oriental pediatrics East West Neo Medical Center at Kyung Hee University and were measured their body composition and bone age. Results There were significant correlations between decreasing of RH-MPH(%) and low weight. 1. As obesity index decreased, the RH-MPH was also decreased. 2. The RH-MPH(%) of the low weight group according to the obesity index classification was significantly decreased than that of the normal weight group. 3. The skeletal maturity was more decreased in the low weight group. However, the differences between the two group was not significant. 4. The RH-MPH(%) was increased in children who developed secondary sexual character. Skeletal maturity was decreased in children who developed secondary sexual character. 5. The RH-MPH(%), and skeletal maturity was not significantly different between males and females. 6. Only in the case of children without development of secondary sexual character, low weight caused significant RH-MPH(%) decrease. Conclusions Low weight children might be smaller than what it supposed to be. Also, low weight could affect body development more to the children than to the teenager.