• Title/Summary/Keyword: MMAE

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Safety of middle meningeal artery embolization for treatment of subdural hematoma: A nationwide propensity score matched analysis

  • Carson P. McCann;Michael G. Brandel;Arvin R. Wali;Jeffrey A. Steinberg;J. Scott Pannell;David R. Santiago-Dieppa;Alexander A. Khalessi
    • Journal of Cerebrovascular and Endovascular Neurosurgery
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    • v.25 no.4
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    • pp.380-389
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    • 2023
  • Objective: Middle meningeal artery embolization (MMAe) has burgeoned as a treatment for chronic subdural hematoma (cSDH). This study evaluates the safety and short-term outcomes of MMAe patients relative to traditional treatment approaches. Methods: In this retrospective large database study, adult patients in the National Inpatient Sample from 2012-2019 with a diagnosis of cSDH were identified. Cost of admission, length of stay (LOS), discharge disposition, and complications were analyzed. Propensity score matching (PSM) was utilized. Results: A total of 123,350 patients with cSDH were identified: 63,450 without intervention, 59,435 surgery only, 295 MMAe only, and 170 surgery plus MMAe. On PSM analysis, MMAe did not increase the risk of inpatient complications or prolong the length of stay compared to conservative management (p>0.05); MMAe had higher cost ($31,170 vs. $10,768, p<0.001) than conservative management, and a lower rate of nonroutine discharge (53.8% vs. 64.3%, p=0.024). Compared to surgery, MMAe had shorter LOS (5 vs. 7 days, p<0.001), and lower rates of neurological complications (2.7% vs. 7.1%, p=0.029) and nonroutine discharge (53.8% vs. 71.7%, p<0.001). There was no significant difference in cost (p>0.05). Conclusions: MMAe had similar LOS and decreased odds of adverse discharge with a modest cost increase compared to conservative management. There was no difference in inpatient complications. Compared to surgery, MMAe treatment was associated with decreased LOS and rates of neurological complications and nonroutine discharge. This nationwide analysis supports the safety of MMAe to treat cSDH.

Implementation and Verification of SOC Estimation Algorithm using MMAE-EKF (MMAE-EKF를 이용한 SOC 추정 알고리즘 구현 및 검증)

  • Yoon, Hyun-Yong;Kim, Dong-Joo;Shin, Seung-Min;Kim, Min-Kook;Lee, Byoung-Kuk
    • Proceedings of the KIPE Conference
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    • 2013.11a
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    • pp.222-223
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    • 2013
  • 본 논문에서는 배터리 SOC 추정 정확도 향상을 위해 기존 EKF 추정 기법에 MMAE 방법을 접목시키는 방법을 제안한다. 노이즈의 세기에 따라 EKF 출력에 비중을 부여함으로써 배터리 사용 전 영역에서 SOC 추정 오차 저감이 가능하며, Matlab 시뮬레이션을 통하여 MMAE-EKF 알고리즘의 타당성을 검증하였다.

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Middle meningeal artery embolization for chronic subdural hematoma in elderly patients at high risk of surgical treatment

  • Jin Hoo Seok;Jong Hyun Kim;Taek Hyun Kwon;Joonho Byun;Won Ki Yoon
    • Journal of Cerebrovascular and Endovascular Neurosurgery
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    • v.25 no.1
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    • pp.28-35
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    • 2023
  • Objective: The purpose of this study was to evaluate the effectiveness of middle meningeal artery embolization (MMAE) in elderly high-risk patients with symptomatic chronic subdural hematoma (CSDH) in terms of reduction in hematoma volume and recurrence rate. Methods: We retrospectively reviewed data prospectively collected from nine patients who underwent 13 MMAE for CSDH between June 2017 and May 2022. The volume of the subdural hematoma was measured using a computer-aided volumetric analysis program. Hematoma volume changes during the follow-up period were analyzed and clinical outcomes were evaluated. Results: The mean follow-up period was 160 days (range, 46-311 days). All procedures were technically successful and there were no procedure-related complications. Of the 13 MMAE, 84% (11 out of 13 hemispheres) showed mean 88% of reduction on follow-up volumetric study with eight cases of complete resolution. There was one refractory case with MMAE which had been performed multiple burr-hole trephinations, for which treatment was completed by craniotomy and meticulous resection of multiple pseudomembranes. There was no recurrent case during the follow-up period, except for refractory case. Conclusions: MMAE for CSDH in selected high-risk elderly patients and relapsed patients might be effective. Despite the small cohort, our findings showed a high rate of complete resolution with no complications. Further prospective randomized trials are warranted to evaluate its usefulness as a primary treatment option for CSDH.

Real time forecasting of rainfall-runoff using multiple model adaptive estimation (다중모델적응추정방식을 이용한 강우-유출량의 실시간 예측)

  • 최선욱;김운해;김영철
    • 제어로봇시스템학회:학술대회논문집
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    • 1996.10b
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    • pp.24-27
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    • 1996
  • The storage function method(SFM) is one of hydrologic flood routings which has been used most widely in Korea and Japan. This paper presents a storage function method using multiple model adaptive estimation(MMAE), in which a model set is generated by partitioning storage parameters over feasible range, and each storage function model is estimated, and then the weighted average of them is calculated. Finally, the future runoff is predicted in real time by means of observed data of water level at dam and rainfall. Simulation results applied to actual data show that the proposed method has much better performance than that of conventional SFM.

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Efficacy of Middle Meningeal Artery Embolization in Treatment Resistant Spontaneous Intracranial Hypotension Caused Subdural Hematoma : Report of Two Cases and Review of the Literature

  • Evran, Sevket;Kayhan, Ahmet;Saygi, Tahsin;Ozbek, Muhammet Arif;Kilickesmez, Ozgur
    • Journal of Korean Neurosurgical Society
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    • v.65 no.6
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    • pp.868-874
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    • 2022
  • Spontaneous intracranial hypotension (SIH) most commonly manifests as bilateral subdural hematoma (SH). SIH cases mostly resolve spontaneously but further treatment would be needed via blind epidural blood patch (EBP). Cerebrospinal fluid (CSF) leakage in EBP-refractory cases can be treated surgically only if the localization of CSF leakage is detectable but it cannot be possible in most of the cases. Also surgical evacuation of SH secondary to SIH (SH-SIH) is not favorable without blocking the CSF leakage. Thus the management of these patients is a challenge and alternative treatment options are needed. Although middle meningeal artery embolization (MMAE) is an effective treatment option in non-SIH SH, there is no report about its application in the treatment of SH-SIH. We present two cases of SH-SIH which their clinical and radiological findings were completely resolved by bilateral MMAE treatment.

Multiple Model Adaptive Estimation of the SOC of Li-ion battery for HEV/EV (다중모델추정기법을 이용한 HEV/EV용 리튬이온전지의 잔존충전용량 추정)

  • Jung, Hae-Bong;Kim, Young-Chol
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.60 no.1
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    • pp.142-149
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    • 2011
  • This paper presents a new state of charge(SOC) estimation of large capacity of Li-ion battery (LIB) based on the multiple model adaptive estimation(MMAE) method. We first introduce an equivalent circuit model of LIB. The relationship between the terminal voltage and the open circuit voltage(OCV) is nonlinear and may vary depending on the changes of temperature and C-rate. In this paper, such behaviors are described as a set of multiple linear time invariant impedance models. Each model is identified at a temperature and a C-rate. These model set must be obtained a priori for a given LIB. It is shown that most of impedances can be modeled by first-order and second-order transfer functions. For the real time estimation, we transform the continuous time models into difference equations. Subsequently, we construct the model banks in the manner that each bank consists of four adjacent models. When an operating point of cell temperature and current is given, the corresponding model bank is directly determined so that it is included in the interval generated by four operating points of the model bank. The MMAE of SOC at an arbitrary operating point (T $^{\circ}C$, $I_{bat}$[A]) is performed by calculating a linear combination of voltage drops, which are obtained by four models of the selected model bank. The demonstration of the proposed method is shown through simulations using DUALFOIL.

The NF-l6D VISTA Simulation System

  • Siouris, George M.
    • Transactions on Control, Automation and Systems Engineering
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    • v.4 no.2
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    • pp.114-123
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    • 2002
  • Called VISTA (Variable-stability In-flight Simulator Test Aircraft), the one-of-a-kind NF-l6D has a simulation system that can mimic several aircraft. Though housed in an F-l6 Fighting Falcon airframe, VISTA can also act like the F-15 Eagle or the Navy's F-14 Tomcat. More importantly, such flexibility allows for improved training and consolidation of some sorties. Consequently USAF Test Pilot School students will have an opportunity to learn how to test future integrated cockpits. In this paper we will use the multiple model adaptive estimation (MMAE) and the multiple model adaptive controller (MMAC) techniques to model the aircraft's flight control system containing the longitudinal and lateral-directional axes. Single and dual actuator and sensor failures will also be included in the simulation. White Gaussian noise will be included to simulate the effects of atmospheric disturbances.

Improvement of Target Motion Analysis for a Passive Sonar System with Measurement Bias Estimation (측정각 Bias 보상을 통한 수동소나체계의 표적기동분석 성능 향상 연구)

  • Yoo, Phil-Hoon;Song, Taek-Lyul
    • Proceedings of the KIEE Conference
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    • 2001.07d
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    • pp.2011-2013
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    • 2001
  • In this paper the MMAE(Multiple Model Adaptive Estimation) algorithm using the MGEKF(Modified Gain Extended Kalman Filter) of which modes are set to be measurement biases is proposed to enhance the performance of target tracking with bearing only measurements. The state are composed of relative position, relative velocity and taregt acceleration. The mode probability is calculated from the bearing only measurements from the HMS(Hull-Mounted Sonar). The proposed algorithm is tested in a series of computer simulation runs.

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