• Asian-Australasian Journal of Animal Sciences
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• v.28 no.6
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• pp.876-887
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• 2015

Dicer, an ribonuclease type III type endonuclease, is the key enzyme involved in biogenesis of microRNAs (miRNAs) and small interfering RNAs (siRNAs), and thus plays a critical role in RNA interference through post transcriptional regulation of gene expression. This enzyme has not been well studied in the Indian water buffalo, an important species known for disease resistance and high milk production. In this study, the primary coding sequence (5,778 bp) of bubaline dicer (GenBank: AB969677.1) was determined and the bubaline Dicer1 biocomputationally characterized to determine the phylogenetic signature among higher eukaryotes. The evolutionary tree revealed that all the transcript variants of Dicer1 belonging to a specific species were within the same node and the sequences belonging to primates, rodents and lagomorphs, avians and reptiles formed independent clusters. The bubaline dicer1 is closely related to that of cattle and other ruminants and significantly divergent from dicer of lower species such as tapeworm, sea urchin and fruit fly. Evolutionary divergence analysis conducted using MEGA6 software indicated that dicer has undergone purifying selection over the time. Seventeen divergent sequences, representing each of the families/taxa were selected to study the specific regions of positive vis-$\grave{a}$-vis negative selection using different models like single likelihood ancestor counting, fixed effects likelihood, and random effects likelihood of Datamonkey server. Comparative analysis of the domain structure revealed that Dicer1 is conserved across mammalian species while variation both in terms of length of Dicer enzyme and presence or absence of domain is evident in the lower organisms.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.17 no.4
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• pp.97-103
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• 2018

Force is a crucial element to be measured in various industries, especially the machine tool industry. Mega units of force are required in fields such as the heavy and ship industries. Micro/nano units of force are required for microparticles. The detection of force generates a physical transformation due to the force imposed from the outside, atlrnd electrical voltage signals are obtained from the system. For the detection of force, an octagonal ring load cell based on circular ring theory is designed and produced. To design the octagonal strain ring, theoretical values with data from the ANSYS program are compared to determine the size of the octagonal strain ring. An octagonal strain ring of the chosen size is made with the SCM415 material. The strain gauges are attached to the octagonal strain ring, designed to construct a full Wheatstone bridge. The LabVIEW program is used to measure the data, and strain values are found. With the octagonal ring load cell completed in this way, experiments are conducted by imposing forces on the tangential axis and radial axis. Experiments are performed to verify if the octagonal ring load cell conducts measurements properly, and theoretical values are analyzed to find any differences. The data will later be used in further research to develop a machine-tool dynamometer.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.9
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• pp.1271-1276
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• 2018

The CPTPP(Comprehensive and Progressive Agreement for Trans-Pacific Partnership) is a large-scale free trade agreement(FTA) in the Asia-Pacific region involving 11 remaining countries(Japan, Australia, New Zealand, Canada, Mexico, Chile, Peru, Singapore, Vietnam, Malaysia and Brunei) since the withdrawal of the US TPP in January 2017, Although the economic size is smaller than the TPP, the CPTPP has 12.9% of the world GDP and 14.9% of the trade volume, meaning that another mega FTA is born. Local economic experts believe that Vietnam's stable economic growth rate and the CPTPP agreement will have a positive impact on Vietnam's stock market and M&A market in 2018. The experts usually expect it will be come into force in 2018 and not later than 2019. The CPTPP is also very likely to enter into force in 2019 with the aggressive attitude of the member countries, simplifying the entry into force of the agreement.

• Journal of the Korea Institute of Building Construction
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• v.10 no.3
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• pp.137-144
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• 2010

As mega-sized and complex building construction projects are on the rise, the importance of project scheduling and control is being highlighted. Project scheduling and control techniques are not yet widely used in Korea, but interest in these has progressively been increasing. Until now, most research projects have mainly focused on scheduling issues, but project progress management is of equal importance. In this research, the current state of project progress management in Korea is analyzed, and ways for improvement are suggested. We begin by analyzing previous research and practical studies in this field, and then survey experts about the current state of project progress management. This study suggests the Building Information Modeling (BIM)base project progress management method for quantitative and qualitative project progress analysis. Currently, BIM is applied to design, construction and maintenance for construction projects. BIM can also contribute to improving accuracy and understanding of the current project situation.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2006.11a
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• pp.390-395
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• 2006

Recently, construction industry demands have been changed by domestic construction circumstances such as high-technology, mega-projects, and the complexity of construction. In order to deal with the change of such a domestic construction circumstances, the Ministry of Construction and Transportation (MOCT) has introduced advanced delivery methods (i..e, CM, DB, etc.). However, the advantages and disadvantages of the advanced delivery methods have not been effectively applied for previous projects. The reason for this is that the "Reviewing Standard for the Large-scale Construction Bidding Method" has not reflected enough project characteristics when the delivery method is selected in the project planning phase. Therefore, this paper proposes the model for selecting criteria of delivery method based on project characteristics in the Multi-housing projects.

• Korean Journal of Construction Engineering and Management
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• v.11 no.3
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• pp.33-42
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• 2010

Recently construction industry has faced new era as following the advances of IT technology. It becomes possible that information and knowledge among people are exchanged actively thanks to computer-based tools. In fact, the tools, PMIS(Project Management Information System) and KMS(Knowledge Management System) already have been introduced to constuction industry successfully. Lately IETM(Interactive Electronic Technical Manual) is tried to be one of these systems. This trying is being enlarged that the IETM's concept is changed to administrative and legal process provider throughout the lifespan of construction projects. However, it is hard to define construction IETM in mega-scale project like urban regeneration project because construction projects are complex and have diverse stakeholders. These properties may make the IETM ambiguous system. To do define IETM as a administrative and legal process provider, this research will conduct survey and interview, then analyze its own properties and find out design strategies. Based on the properties and strategies, suggesting IETM's system demands and architecture of urban regeneration processes.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2001.05a
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• pp.524-527
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• 2001

According to the very rapid technological change and market mega-trends, the ITU(International Telecommunication Union) is now under Reform. In line with whole ITU reform, ITU-T (ITU- Telecommunications Standardization Sector) as global standards development organization has setup the two major environment such as ITU-T resolutions and new standards approval process for new study period 2001-2904 in the WTSA-2900. In this paper, we analyze on detailed EDH(Electronic Document Handling) activities, EDH related resolution and Methods as strategic tools within the ITU-T and its application to the New approval process which is described in ITU-T Recommendation A.8(AAP). Finally, we discuss future ITU-T EDH policy and suggest direction of Korean EDH policy.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.10
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• pp.6504-6510
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• 2015

Horizontally curved I-girders are subjected to not only bending moments but also torsional moments. The torsional moment of the plate girder is addition of St. Venant torsion and non-uniform torsion. In the flange of I-shaped plate girder, a kind of open-section, the normal stresses is not distributed uniformly due to the non-uniform torsion. Because of that, one of compression flange tip can be yielded faster than the flange of general straight girder. In other words, the flange local buckling strength is decreased when the girder has initial curvature. In this paper, the numerical analysis is conducted to investigate the average stresses in flange for curved girders. The subtended angle and slenderness ratio are taken as parameters.

• Explosives and Blasting
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• v.25 no.2
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• pp.11-21
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• 2007

The main structure of Gunsan steam power station was demolished by the toppling method using high explosives. Height of a main building is 58m and a total floor area is $292,000m^2$. It is Rahmen(rigid-frame) structure consisted of almost columns and beams and slabs exist only in one part of the building for the electricity generators equipments. To improve the efficiency of blasting work, it is separated into 4 sectors. Blasting floors were 1, 2, 3, & 4 stories from first sector to third sector, while 1, 2, 5, & 7 of fourth sector were blasted because it had not slabs. About 102.675 kg of the MegaMITE were used with 225 electric detonator and 638 non-electric detonators to check detonator connection and confidence of detonation. The blasting noise and vibration were monitored to evaluate the environment effect and the damage of the nearby structures.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.25 no.6_1
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• pp.545-555
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• 2007

3D buildings are the most prominent feature comprising urban scene. A few of mega-cities in the globe are virtually reconstructed in photo-realistic 3D models, which becomes accessible by the public through the state-of-the-art online mapping services. A lot of research efforts have been made to develop automatic reconstruction technique of large-scale 3D building models from remotely sensed data. However, existing methods still produce irregular building polygons due to errors induced partly by uncalibrated sensor system, scene complexity and partly inappropriate sensor resolution to observed object scales. Thus, a geometric regularization technique is urgently required to rectify such irregular building polygons that are quickly captured from low sensory data. This paper aims to develop a new method for regularizing noise building outlines extracted from airborne LiDAR data, and to evaluate its performance in comparison with existing methods. These include Douglas-Peucker's polyline simplication, total least-squared adjustment, model hypothesis-verification, and rule-based rectification. Based on Minimum Description Length (MDL) principal, a new objective function, Geometric Minimum Description Length (GMDL), to regularize geometric noises is introduced to enhance the repetition of identical line directionality, regular angle transition and to minimize the number of vertices used. After generating hypothetical regularized models, a global optimum of the geometric regularity is achieved by verifying the entire solution space. A comparative evaluation of the proposed geometric regulator is conducted using both simulated and real building vectors with various levels of noise. The results show that the GMDL outperforms the selected existing algorithms at the most of noise levels.