• The Korean Journal of Physiology
• /
• v.23 no.2
• /
• pp.225-236
• /
• 1989

1) At the isolated perfused guinea-pig and rat heart heterometric autoregulation of the myocardium and myogenic autoregulation of the coronary vessels were induced by means of stepwise increases of perfusion pressure. 2) According to this loading test Frank-Starling function curves of the left ventricle and pressure-flow curves of the coronary vessels can be drawn. This graphic evaluation gives more information about the condition of the heart and the coronary vessels than simple evaluation under hemodynamic equilibrium. 3) There are significant differences in both curves between animal species and between different perfusate Mg concentration. 4) Myogenic autoregulation is not affected by the cyclooxygenase inhibitors indometacin and me- clofenamate. Thus it appears unlikely that prostanoides are involved in myogenic autoregulation. 5) Ca antagonists (Gallopamil, prenylamine) depress myogenic autoregulation dose-dependently. Enhanced myogenic autoregulation, induced by low extracellular magnesium, can be reduced effectively by Gallopamil. 6) Ginsenosides from Panax ginseng as well as the ginsenoside 'Rg' are effective inhibitors of myogenic autoregulation without major negative inotropic effects.

• Nuclear Engineering and Technology
• /
• v.55 no.3
• /
• pp.1015-1020
• /
• 2023

A multi-layer design is applied to mitigate single event effect (SEE) in a 28 nm System-on-Chip (SoC). It depends on asymmetric multiprocessing (AMP), redundancy and system watchdog. Irradiation tests utilized 70 and 90 MeV proton beams to examine its performance through comparative analysis. Via examining SEEs in on-chip memory (OCM), compared with the trial without applying the multi-layer design, the test results demonstrate that the adopted multi-layer design can effectively mitigate SEEs in the SoC.

• Journal of Life Science
• /
• v.20 no.8
• /
• pp.1241-1248
• /
• 2010

The solvent extracts of Nelumbo nucifera G. were investigated for antioxidant activities, whitening and anti-wrinkle effects to apply as a functional ingredient in cosmetic products. For their industrial application, the cosmetic products were also prepared with advanced formulation techniques such as W/O/W multiple emulsion. Total phenolic and flavonoids contents increased in Nelumbo nucifera G.-Leaf (NN-L). The electron donating ability of Nelumbo nucifera G.-Flower (NN-F) or Nelumbo nucifera G.-Leaf (NN-L) extracts were above 85% at a concentration of 500 ppm. The superoxide dismutase (SOD)-like activity of Nelumbo nucifera G. (NN-L) extracts was about 60% at a concentration of 1,000 ppm. The xanthine oxidase inhibitory effect of NN-L extract was higher than that of NN-F and NN-S extracts. The tyrosinase inhibitory effect, which is related to skin-whitening, was 36% in NN-F at 1,000 ppm. For anti-wrinkle effect, the elastase inhibition activity of NN-L was about 30% at 1,000 ppm. The results of stability test showed that W/O/W multiple emulsion (ME) containing Nelumbo nucifera G. extracts. The electron donating ability of the ME containing NN-F and NN-L were about 60% at a concentration of 100 ppm. The superoxide dismutase (SOD)-like activity of the ME containing NN-L was 30% at 1,000 ppm. The tyrosinase inhibitory effect, which is related to skin-whitening, was 34% in the ME containing NN-F at 1,000 ppm. In anti-wrinkle effect, the elastase inhibition activity of the ME containing NN-L was about 55% at 1,000 ppm.

• Journal of the Korean Society for Nondestructive Testing
• /
• v.23 no.4
• /
• pp.349-355
• /
• 2003

Material degradation due to corrosion fatigue was evaluated nondestructively using backward radiated Rayleigh surface wave. h corrosion fatigue test was carried out for the specimens made of thermo-mechanically controlled process steel in 3.5wt.% NaCl solution at $25^{\circ}C$. The backward radiation profile, which is the amplitude variation of backward radiated ultrasound according to the incident angle, of the specimens were measured in water at room temperature after the corrosion fatigue test. The velocity of Rayleigh surface wave, determined from the incident angle at which the profile of the backward radiated ultrasound became maximum, decreased for the specimen that had the large number of cycles to failure in the corrosion fatigue test. This fact implies that the corrosion degradation occurred at specimen surface in this specific test is dominantly dependant on the me exposed to corrosion environment. The result observed in the present work demonstrates the high potential of backward radiated Rayleigh surface wave as a tool for nondestructive evaluation of corrosion degradation of aged materials.

• The Mathematical Education
• /
• v.56 no.2
• /
• pp.177-191
• /
• 2017

This study was to investigate the effect of the statistics education program for the test-free semester. Two tests of questionnaires were used after revising some items for the subjects and statistical contents covered according to the purpose of the study during the 2nd semester, 2016. one was for finding students' attitude toward statistics and the other for understanding my career exploration. The statistics education program was developed for 5 lesson units and was applied to two classes with 53 students of one middle school in Gyeonggi-province. The results showed that students' understanding on career exploration was improved especially, in self understanding, perceiving career world related to statistics, and economical & educational understanding in statistical career. Also, the three areas such as interest, value, and effort among five areas about students' statistical attitude which was measured by the attitude test revised from the previous study, were improved with statistical significance. Moreover, we analyzed the degree of students' satisfaction over the program. Most of students were satisfied with the program saying that "I could not believe it is over now. The time has gone so fast." or "My mentor(a pre-service teacher) helped me a lot." Therefore, the program for the test-free semester should include the contents for exploring future-career and relating to real life.

• The Journal of Korean Academic Society of Nursing Education
• /
• v.6 no.1
• /
• pp.92-102
• /
• 2000

Social trends influence the need for inclusion of basic concepts of occupational health into generic nursing education. Several techniques have been used to incorporate occupational health into baccalaureate programme. These include clinical preceptorships in employee health services, lectures on occupational health issues into community health nursing courses and the integration of occupational health concepts throughout the nursing curriculum and organize an independent course of occupational health nursing for two semester hours. The purpose of this study was to examine the impact of this course to the role orientation of nursing students. In March 1998, pre-test was conducted with all 39 students. Post- test for the subjects and the survey for the other comparison group were conducted after the course in May. Structured questionnaires were distributed which were composed of 42 items related to the role of occupational health nurse and each item was measured on a scale of 1 to 5. Results are as follows: 1) The paired t-test supported the hypothesis that role orientation of students was improved through the occupational health nursing course (t=-3.93, p=.000), 2) As the result of t-test between the subject and the comparison group, the mean score of the role orientation in the case of subject was significantly higher than that of the comparison group(t=13.3449, p=.0005). The enlargement of occupational health nursing course must be a facilitating factor to the improvement of the role orientation of baccalaureate students. It is needed to measure occupational health nursing competence of them in the future.

• Natural Product Sciences
• /
• v.4 no.2
• /
• pp.105-114
• /
• 1998

The antimutagenic activity of a methanol extract of Ecklonia stolonifera (Laminariaceae) against aflatoxin $B_1\;(AFB_1)$ was demonstrated with the Salmonella typhimurium assay. The numbers of revertants per plate decreased significantly when this extract was added to the assay system using S. Salmonella typhimurium TA100. The methanol extract also exhibited significant inhibitory effects on the micronuclei formation in mouse peripheral blood reticulocytes and the DNA damage in mouse spleen lymphocytes induced by N-methyl-N-nitrosourea (MMU) and benzo(a)pyrene (B(a)P). The MeOH extract was then sequentially partitioned with $CH_2Cl_2,\;CH_2Cl_2$ insoluble intermediate, EtOAc, n-BuOH, and $H_2O$. All fractions possessed antimutagenic activity but the $H_2O$ fraction was inactive. Among active fractions, the EtOAc and $CH_2Cl_2$ insoluble intermediate fractions showed the highest activity. Column chromatography using $SiO_2$ and Sephadex LH-20 yielded phloroglucinol from the EtOAc fraction. Phloroglucinol also demonstrated significant antimutagenic activity, and inhibitory effects on the micronuclei formation in mouse peripheral blood reticulocytes and DNA damage in mouse spleen lymphocytes induced by MMU and B(a)P.

• The Journal of the Korea institute of electronic communication sciences
• /
• v.15 no.4
• /
• pp.725-732
• /
• 2020

This paper uses variables following as : to follow me well(0-9), it takes a lot of time to make a decision (0-9), lethargy(0-9) during physical activity in the exercise learning program of the children in the marginalized class. This paper classifies 'gender', 'physical education classroom', and 'upper, middle and lower' of age, and observe changes in ego-resiliency and self-control through sports rehabilitation therapy to find out changes in mental health. To achieve this, the data acquired was merged and the characteristics of large and small numbers were removed using the Label encoder and One-hot encoding. Then, to evaluate the performance by applying each algorithm of MLP, SVM, Dicesion tree, RNN, and LSTM, the train and test data were divided by 75% and 25%, and then the algorithm was learned with train data and the accuracy of the algorithm was measured with the Test data. As a result of the measurement, LSTM was the most effective in sex, MLP and LSTM in physical education classroom, and SVM was the most effective in age.

• Imaging Science in Dentistry
• /
• v.33 no.3
• /
• pp.171-178
• /
• 2003

Purpose: The purpose of this study was to report the reproducibility of intra-observer and inter-observer consistency of cephalometric measurements using three-dimensional (3D) computed tomography (CT), and the degree of difference of the cephalometric measurements. Materials and Methods: CT images of 16 adult patients with normal class I occlusion were sent to personal computer and reconstructed into 3D images using V-Works 3.5/sup TM/(Cybermed Inc., Seoul, Korea). With the internal program of V-Works 3.5/sup TM/, 12 landmarks on regular cephalograms were transformed into 21 analytic categories and measured by 2 observers and in addition, one of the observers repeated their measurements. Intra-observer difference was calculated using paired t-test, and inter-observer by two sample test. Results: There were significant differences in the intra-observer measurements (p < 0.05) in four of the categories which included ANS-Me, ANS-PNS, Cdl-Go (Lt), GoL-GoR, but with the exception of Cdl-Go (Lt), ZmL-ZmR, Zyo-Zyo, the average differences were within 2 mm of each other. The inter-observer observations also showed significant differences in the measurements of the ZmL-ZmR and Zyo-Zyo categories (p < 0.05). With the exception of the Cdl-Me (Rt), ZmL-ZmR, Zyo-Zyo categories, the average differences between the two observers were within 2 mm, but the ZmL-ZmR and Zyo-Zyo values differed greatly with values of 8.10 and 19.8 mm respectively. Conclusion: In general, 3D CT images showed greater accuracy and reproducibility, with the exception of suture areas such as Zm and Zyo, than regular cephalograms in orthodontic measurements, showing differences of less than 2 mm, therefore 3D CT images can be useful in cephalometric measurements and treatment planning.

• Korean Journal of Oriental Medicine
• /
• v.3 no.1
• /
• pp.67-83
• /
• 1997

In order to search for anti-influenza virus type A agents from Korean medicinal herbs, we selected 100 medicinal herbs, based on a review of the Korean traditional medicine books. Four of 100 Korean medicinal herbs, MM-40, MM-55, MM-63, MM-110, exhibited very strong anti-influenza virus activity. The fractions of four medicinal herbs, which had very strong anti-influenza virus activity, were tested for antiviral activity by means of Haemagglutination inhibition test(HTT), 40% MeOH fraction of MM-40, $H_2O$ fraction of MM-55, 20% fraction of MM-63 3nd $H_2O$ fraction of MM-110 had strong anti-influenza virus activity at the range of $78{\mu}g/ml$ to $156{\mu}g/ml$, 1.56mg/ml to 100mg/ml, 6.25mg/ml to 50mg/ml and $48.7{\mu}g/ml$ to $780{\mu}g/ml$, respectively. These results of HIT indicated that fractions of Korean medicinal herbs might inhibit either attachment of virus to cell surface receptor or penetration of virus into cell during the initial stage of infection. In the cytotoxicity of fractions against red blood cells, 40% MeOH fraction of MM-40, 20% fraction of MM-63 and $H_2O$ fraction of MM-110 showed cytotoxicity at the range of $78{\mu}g/ml$ to 10mg/ml, 50mg/ml to 100mg/ml and $195{\mu}g/ml$ to 100mg/ml, respectively, whereas $H_2O$ fraction of MM-55 did not show cytotoxicity. In order to establish influenza virus adapted animal model, influenza virus type A were passaged 3 and 4 times successively in Balb/c mouse. As a result, we had 4 HA unit titers on the 5 days of 3rd passages and 7 days of 4th passages after infection, respectively.