• Development and Reproduction
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• v.10 no.3
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• pp.169-175
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• 2006

Ginseng is the best known and most popular herbal medicine used worldwide. In spite of reported beneficial effects of ginseng on the CNS, there is few scientific evidences established at the cellular level. Among more than 30 ginsenosides, Rb1 and Rg1, the active ingredients of ginseng, are regarded as the main compounds responsible for many pharmaceutical actions of ginseng. Daily treatment with Rb1 or Rg1 for 3 d significantly decreased the number of bromodeoxyuridine(BrdU)(+) cells in primary neural progenitor cells(NPCs) isolated from hippocampi at embryonic day 16.5(E16.5). In contrast, treatment with Rb1 or Rg1 greatly increased the number of microtubule associated protein(MAP2) (+) cells. In addition, the transcription factors, Ngn1 and Hes1, proneural members of the basic helix-loop-helix(bHLH) family, significantly increased in Rb1 or Rg1 treated-NPCs. Based on these results, we suggest for the first time that ginsenosides Rb1 and Rg1 decrease proliferation but promote neuronal differentiation of hippocampal NPCs.

• Journal of Advanced Navigation Technology
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• v.16 no.3
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• pp.417-425
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• 2012

It is well known that GPS cannot provide positioning results if sufficient number of visible satellites are not available. To overcome this weak point, attentions have been recently moved to hybrid positioning methods that augments GPS with other sensors. As an extension of hybrid positiong methods, this paper proposes a new method that combines GPS and vision sensor to improve availability and accuracy of land vehicle positioning. The proposed method does not require any external map information and can provide position solutions if more than 2 navigation satellites are visible. To evaluate the performance of the proposed method, an experiment result with real measurements is provided and a result shows that accumulated error of n-axis is almost 2.5meters and that of e-axis is almost 3meters in test section.

• Journal of Microbiology and Biotechnology
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• v.19 no.7
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• pp.647-650
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• 2009

Using 200 porcine colon tissues, the efficiencies of three isolation methods of Campylobacter from porcine intestines were compared: Method 1, direct streaking of colon mucosa; Method 2, direct inoculation of intestinal contents with a swab; Method 3, inoculation of pre-enriched medium. A total of 460 Campylobacter isolates were obtained from 178 samples (89%) by direct streaking of colon mucosa, 142 samples (71%) by direct streaking of a swab, and 94 samples (47%) by pre-enrichment of intestinal contents in Preston broth. Direct streaking of colon mucosa was superior to the other two isolation methods, in terms of rapidity and higher efficiency. When isolates were identified with various biochemical tests and PCRs specific to 16s rRNA, mapA, and ceuE, C. coli was the predominant species (87%) in porcine, whereas the rest of the isolates were identified as C. lanienae.

• Proceedings of the KSAR Conference
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• 2001.03a
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• pp.48-48
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• 2001

A new neurological mutant has been found in the ICR outbred strain mouse. Affected mice display profound deafness and a head-tossing and bidirectional circling behavior, showing an autosomal recessive mode of inheritance. It was, therefore, named cir/Kr with the gene symbol cir. The auditory tests identified clearly the hearing loss of the cir mice when compared to wild type mice. Pathological studies confirmed the developmental defects in the middle ear, cochlea, cochlear nerve, and semicircular canal areas, which were correlated to the abnormal behavior observed in the cir mice. Thus, cir mice may be useful as a model for studying inner ear abnormalities and deafness. We have constructed a genetic linkage map by positioning 14 microsatellite markers across the (cir) region and intraspecific backcross between cir and C57BL/6J mice. The cir mouse harbors an autosomal recessive mutation on mouse chromosome 9. The cir gene was mapped to a region between D9Mit116 and D9Mit38 Estimated distances between cir and D9Mit116, and between cir and D9Mit38 are 0.7 and 0.2 cM, respectively. The gene in order was defines : centromere-D9Mit182-D9Mit51/D9Mit79/D9Mit310-D9Mit212/D9Mit184-D9Mit116-cir-D9Mit38-D9Mit20-D9Mit243-D9Mit16-D9Mit55/D9Mit125-D9Mit281. The mouse map location of the cir locus appears to be in a region homologous to human 3q21. Our present date suggest that the nearest flanking marker D9Mit38 provides a useful anchor for the isolation of the cir gene in a yeast artificial chromosome contig.

• Journal of Broadcast Engineering
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• v.16 no.5
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• pp.801-810
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• 2011

This paper proposes a new lossless data embedding algorithm on spatial domain of digital images. A single key parameter is required to embed and extract data in the algorithm instead of embedding any additional information such as the location map. A $3{\times}3$ window slides over the cover image by one pixel unit, and one bit can be embedded at each position of the window. So, the ideal embedding capacity equals to the number of pixels in an image. For further increase of embedding capacity, new weight parameters for the estimation of embedding target pixels have been used. As a result, significant increase in embedding capacity and better quality of the message-embedded image in high capacity embedding have been achieved. This algorithm is verified with simulations.

• Journal of the Korean Association of Geographic Information Studies
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• v.16 no.3
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• pp.54-67
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• 2013

This study deals with the characteristics of view landscape in modern Daegu city which were analysed employing geographic information system(GIS). The view landscape analysis was performed by using GIS that enables to overlap land use map with the map of range of visibility, and the 3-D simulation. The results are as follows; First of all, the ratio of forest is enormously high in the range of visibility. The distribution of landscape components allows the dwellers to obtain a clear view towards forests from anywhere. The landscape components include west eroded lowlands, east open rolling lands, east eroded lowlands, and high mountain areas: Apsan(Mt.) in the south; Waryoungsan(Mt.) in the west; and Hamjisan(Mt.) and Hakbong(Mt.) in the north. On the tops of those, people are able to secure a clear vision from the viewpoint towards the surrounding mountains because of the rural areas continuing from the viewpoint to the mountains. A continuous view landscape has been formed by these natural environmental factors. Finally, there are multiple view targets with relatively high altitude that are covered with forests in the space between the urban area and the outer mountains that are higher than the view targets, which provides a scenery of mountains overlapped by higher mountains.

• Korean Journal of Ecology and Environment
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• v.48 no.2
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• pp.122-128
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• 2015

This study aims to figure out the vegetation status and characteristics of the spatial distribution in Taeanhaean National Park. As a result, vegetation communities were Pinus thunbergii community, Pinus densiflora community, Pinus thunbergii-Pinus densiflora community, Camellia japonica community, Carpinus turczaninowii community, Carpinus turczaninowii-Pinus thunbergii community, Kalopanax septemlobus community, Koelreuteria paniculata community, Robinia pseudoacacia community, and sand dune and coastal wetland vegetation including Vitex rotundifolia community, Elymus mollis community, Calamagrostis epigeios community, Ischaemum anthephoroides community, Zoysia sinica community, Suaeda maritima community, and Phragmites communis community. Landscape types in actual vegetation map were Pinus thunbergii community (3.92%), Pinus densiflora community (1.40%), Robinia pseudoacacia community (0.05%), sand dune and coastal wetland vegetation (0.11%), field (0.46%), seashore (0.24%), thinning area (0.08%), bareground (0.16%), and sea (93.58%). Area of Pinus thunbergii community among vegetation type was $14.797km^2$ (3.92%) and the largest. Stratification structure and species composition of Pinus thunbergii community distributed in the seashore were different as a result of disturbance and human use. On the other hand, we assumed that succession will take place to the potential natural vegetation that is Quercus serrata and Quercus dentata in undisturbed Pinus thunbergii community. Meanwhile, Erechtites hieracifolia was occupied in understory of Pinus thunbergii community around the seashore and Diodia teres was invaded to sand dune vegetation. They may affect on natural species negatively. Therefore, monitoring and management plans are necessary.

• JSTS:Journal of Semiconductor Technology and Science
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• v.16 no.5
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• pp.713-718
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• 2016

Predicting precise specifications of differential mixed-signal circuits is a difficult problem, because analytically derived correlation between process variations and conventional specifications exhibits the limited prediction accuracy due to the phase unbalance, for most self-tests. This paper proposes an efficient prediction technique to provide accurate specifications of differential mixed-signal circuits in a system-on-chip (SoC) based on a nonlinear statistical nonlinear regression technique. A spectrally pure sinusoidal signal is applied to a differential DUT, and its output is fed into another differential DUT through a weighting circuitry in the loopback configuration. The weighting circuitry, which is employed from the previous work [3], efficiently produces different weights on the harmonics of the loopback responses, i.e., the signatures. The correlation models, which map the signatures to the conventional specifications, are built based on the statistical nonlinear regression technique, in order to predict accurate nonlinearities of individual DUTs. In production testing, once the efficient signatures are measured, and plugged into the obtained correlation models, the harmonic coefficients of DUTs are readily identified. This work provides a practical test solution to overcome the serious test issue of differential mixed-signal circuits; the low accuracy of analytically derived model is much lower by the errors from the unbalance. Hardware measurement results showed less than 1.0 dB of the prediction error, validating that this approach can be used as production test.

• Korean Journal of Remote Sensing
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• v.33 no.5_3
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• pp.867-878
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• 2017

Recent interest in geological heritage has been increased in that it can be used as a basic data onto predicting the global environmental change of its containing information about past global environment. In addition, due to the characteristics of the geological heritage, it is easy to damage and difficult to recover without continuous preservation and management. However, there are more damages occurring because of the sporadic spatial distribution and ambiguous management authority of geological heritage. Therefore, an integrated management system is needed by determining the spatial distribution of geological heritage preferentially. In this study, the detailed criteria for assessment of value from the preliminary studies were applied and the geological heritage grade distribution map was generated by using geospatial data in Seoul metropolitan area. For this purpose, the list of geological heritage sites in the Seoul metropolitan area, which is the study area, were complied through a literature review. The geospatial database was designed and constructed by applying the detailed criteria for assessment of value from the preliminary studies. After the construction of the spatial database, a grade map of the geological heritage was created. As a result of the geological heritage grade map in the Seoul metropolitan area, there were more than 35% of the geological heritage in northern Gyeonggi provinces such as Yeoncheon city (18.8%), Pocheon city (10.6%) and Paju city (6.3%). It is followed by 18.1% in Incheon and 8.1% in Ansan, which is approximately 26.2% in western Gyeonggi Province. The geological age of the geological heritage was the highest at in the fourth stage of the Cenozoic era of 16.9%. Through the results of this study, the geological heritage data of the Seoul metropolitan area were extracted from existing literature data and converted into spatial information. It enables comparing the geological features with the spatial distribution of geological heritage. In addition, a management system has been established based on spatial information of constantly building geological heritage data. This provides the integrated management system of the geological heritage to manage authority so that it can be used as a basis for the development of the geological park. Based on the results of this study, it is considered to be possible to systematically construct and utilize the geological heritage across the country.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.2
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• pp.47.2-47.2
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• 2016

We introduce a magnetic field survey of the Gould Belt clouds using the James Clerk Maxwell Telescope (JCMT) POL-2: B-fields In STar-forming Region Observations (BISTRO). POL-2 with SCUBA-2 on JCMT is a unique facility, as it is the only facility world-wide that can map the magnetic field within cold dense cores and filaments on scales of ~1000 AU in nearby star-forming regions, such as Taurus and Ophiuchus. It can provide a link between the B-field measured on arc-minute scales by Planck and BLASTPOL and measurements made on arc-second scales by interferometers such as CARMA, SMA, and ALMA. BISTRO was awarded 224 hours toward 16 fields for the next 3 years and started to take data in the 2016A semester.