• Title/Summary/Keyword: M49

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A Design of PDA-based Protocol for Credit Card Transaction on Wireless Internet (무선인터넷 환경에서 PDA기반 신용카드 결제 프로토콜 설계)

  • 이여진;정일용
    • Proceedings of the Korea Multimedia Society Conference
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    • 2004.05a
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    • pp.49-52
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    • 2004
  • M-Commerce에서 안전한 서비스를 제공하기 위해서는 보안 기능을 갖춘 결제 솔루션이 필수적이다. M-Commerce를 이응하기 위한 사용자의 이동 단말기는 핸드폰, PDA, 스마트폰 등으로 다양화 되어가고 있으며, 이 중에서도 PDA의 인터페이스와 이동 접속은 기존 핸드폰의 유선 인터넷의 정보 의존도가 높은 단점을 극복할 수 있다. 본 논문에서는 타원곡선 암호를 이용하여 PDA 기반의 신용카드 결제 시스템을 설계하였다. 제안된 시스템의 SECURE CARD 모듈은 PDA 단말기 자체에 개인정보, 배송정보, 카드정보를 암호화하여 안전하게 저장함으로써 단말기의 정보입력시에 필요한 불편함을 제거하였다. 또한 프로토콜은 M-Commerce에서 인증, 기밀성, 무결성, 부인봉쇄 서비스 둥의 보안기능을 제공하도록 설계되었다.

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Optimization of mixing ratio of Polygala tenuifolia, Angelica dahurica and Elsholtzia splendens extracts for cosmetic material development (화장품 소재 개발을 위한 원지 (Polygala tenuifolia), 백지(Angelica dahurica) 및 꽃향유 (Elsholtzia splendens) 추출물의 혼합 비율 최적화)

  • Jung Seo A;Song, Ga Hyeon;Su In Park;Jung, Youn Ok
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.6
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    • pp.993-1000
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    • 2023
  • Recently, enviromentally friendly natural substances derived from plants have been attracting attention as cosmetic materials, and research on various physiological activities of natural substances is being actively conducted. This study investigated the antioxidant, anti-inflammatory, moisturizing, and antibacterial effects of three types of extracts of mixtures containing different mixing ratios, Polygala tenuifolia, Angelica dahurica, and Elsholtzia splendens, known to have various physiological activities. The mixing ratio is 7 conditions (M1, 1:1:1; M2, 0.5:1.5:1; M3, 1.5:0.5:1; M4, 0.1:0.95:0.95; M5, 0.5:0.5:2; M6, 0.95 :1.95:0.1; M7, 1.45:0.1:1.45), and the optimal mixing ratio was confirmed for use as a cosmetic material. DPPH and ABTS radical scavenging activities showed scavenging abilities of 75.37% and 99.19%, respectively, at 1,000 ㎍/mL of M6. At a concentration of 200 ㎍/mL of M6, it showed 50% of nitric oxide production inhibition compared to the lipopolysaccharide-treated that induced an inflammatory response. It was confirmed that M3 and M6 produced hyaluronic acid 1.47 and 1.49 times higher than the control at a concentration of 50 ㎍/mL, respectively. Through the disc diffiusion test, the clear zone was 9.75 mm at 8 ㎍/mL of M6, confirming the inhibition of growth of staplylococcus aureus strain. Based on the above results, it is believed that the mixed extract of Polygala tenuifolia, Angelica dahurica, and Elsholtzia splendens can be used as a functional natural material for cosmetics.

Inhibition of Inducible Nitric Oxide Synthase Expression by YS 49, a Synthetic Isoquinoline Alkaloid, in ROS 17/2.8 Cells Activated with $TNF-{\alpha},\;IFN-{\gamma}$ and LPS

  • Kang, Young-Jin;Kang, Sun-Young;Lee, Young-Soo;Park, Min-Kyu;Kim, Hye-Jung;Seo, Han-Geuk;Lee, Jae-Heun;YunChoi, Hye-Sook;Chang, Ki-Churl
    • The Korean Journal of Physiology and Pharmacology
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    • v.8 no.5
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    • pp.273-280
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    • 2004
  • Nitric oxide (NO) has been suggested to act as a mediator of cytokine-induced effects of turn over of bone. Activation of the inducible nitric oxide synthase (iNOS) by inflammation has been related with apoptotic cell death in osteoblast. YS 49, a synthetic isoquinoline alkaloid, inhibits NO production in macrophages activated with cytokines. In the present study, we investigated the molecular mechanism of YS 49 to inhibit iNOS expression in ROS 17/2.8 cells, which were activated with combined treatment of inflammatory cytokines $(TNF-{\alpha},\;IFN-{\gamma})$ and lipopolysaccharide (LPS). Results indicated that YS 49 concentration-dependently reduced iNOS mRNA and protein expression, as evidenced by Northern and Western blot analysis, respectively. The underlying mechanism by which YS 49 suppressed iNOS expression was not to affect iNOS mRNA stability but to inhibit activation and translocation of $NF-_kB$ by preventing the degradation of its inhibitory protein $I_kB_{\alpha}$. As expected, YS 49 prevented NO-induced apoptotic cell death by sodium nitroprusside. Taken together, it is concluded that YS 49 inhibits iNOS expression by interfering with degradation of phosphorylated inhibitory $_kB_{\alpha}\;(p-I_kB_{\alpha})$. These actions may be beneficial for the treatment of inflammation of the joint, such as rheumatoid arthritis.

Isolation and Characterization of a Novel Polysaccharide Producing Bacillus polymyxa A49 KCTC 4648P

  • Ahn, Sung-Gu;Suh, Hyun-Hyo;Lee, Chang-Ho;Moon, Seong-Hoon;Kim, Hee-Sik;Ahn, Keug-Hyun;Kwon, Gi-Seok;Oh, Hee-Mock;Yoon, Byung-Dae
    • Journal of Microbiology and Biotechnology
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    • v.8 no.2
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    • pp.171-177
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    • 1998
  • The strain A49, which produces a new type of extracellular polysaccharide was isolated from soil samples. From morphological, physiological and biochemical tests, the strain A49 was identified as a Bacillus polymyxa and named Bacillus polymyxa A49. Bacillus polymyxa A49 was found to produce a highly viscous extracellular polysaccharide when grown aerobically in a medium containing glucose as the sole source of carbon. The polysaccharide (A49 POL) showed a homogeneous pattern on gel permeation chromatography (GPC) and its molecular weight was estimated to be about 1.6 mega dalton (mDa). The FT-IR spectrum of A49-POL revealed typical characteristics of polysaccharides. As a result of investigations with HPLC and carbozole assay, A49-POL was found to consist of L-fucose, D-galactose, D-glucose, D-mannose, and D-glucuronic acid, with the molar ratio of these sugars being approximately 1:2:7:50:12. Rheological analysis of A49 POL revealed that it is pseudoplastic and has a higher apparent viscosity at dilute concentrations than does xanthan gum. The consistancy factor of A49 POL was found to be higher, and the flow index of A49 POL lower, than xanthan gum. Its apparent viscosity was comparatively unstable at various temperatures. the A49 POL showed the highest apparent viscosity at pH 3. When salts were added to A49 POL solution, the solution was compatible with up to 10% KCl, 35% NaCl, 55% $CaCl_2$, 55% $MgCl_2$, 55% $K_2HPO_4$, and 110% $Ca({NO_3})_2$, respectively.

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Isolation of Xylitol-Producing Thermotolerant Yeast Millerozyma farinosa from Nuruk (누룩으로부터 자일리톨 생산능이 있는 내열성 효모 Millerozyma farinosa 균주의 분리)

  • Jung, Eun-Hye;Bae, Young-Woo;Kwun, Se-Young;Park, Eun-Hee;Kim, Myoung-Dong
    • Microbiology and Biotechnology Letters
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    • v.47 no.4
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    • pp.530-535
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    • 2019
  • Diverse types of nuruks (traditional Korean fermentation initiators) were examined in order to isolate thermotolerant yeast strains capable of utilizing xylose as a carbon source. Among twenty yeast strains that grew at 46℃, MBY/L1597 showed a notably higher specific growth rate than other strains. This strain was identified as Millerozyma farinosa. While the control strain M. farinosa KCTC27412 (= CBS7064) did not show xylose reductase (XR) activity and apparent growth at 46℃, M. farinosa MBY/L1597 exhibited XR activity of 4.98 ± 0.49 U/mg protein when NADPH was used as a cofactor. M. farinosa MBY/L1597 cultured at 46℃ produced (9.87 ± 1.00 g/l) xylitol from 20 g/l xylose, corresponding to approximately 50% yield. M. farinosa MBY/L1597 was deposited at the Korean Collection for Type Cultures as KCTC27797.

A Development of M-Learning Contents for Improving the Learning Ability of Military Education (군 교육의 학습 능력 향상을 위한 M-러닝 콘텐츠 개발)

  • Chang, Jeong-Uk;Lin, Chi-Ho
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.12 no.6
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    • pp.25-32
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    • 2012
  • In this paper, we proposed a development of M-learning smart-trainer content for improving the learning ability of military education. Learners of time and space constraints beyond quickly and accurately can learn with the goal, each subject by partial learning, and repetition, the whole learning quickly and easily by selecting efficiently to help you learn a m-Bizmaker with applications was designed. Experiment targets the military company of two, first aid courses were conducted for the evaluation. Traditional collective comparison group teaching methods, the proposed content, teaching methods applied in the experimental group were selected. The proposed learning applications using smart instructor for verification of learning, with which to compare, test subjects were compared with each of 49 subjects, the results p<.005 level, there was difference among the two groups. Therefore, the proposed application using a smart trainer after class proved that contribute to improving achievement.

Aloe-emodin inhibits Pam3CSK4-induced MAPK and NF-κB signaling through TLR2 in macrophages

  • Lee, Mi Jin;Park, Mi-Young;Kim, Soon-Kyung
    • Journal of Nutrition and Health
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    • v.49 no.4
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    • pp.241-246
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    • 2016
  • Purpose: Aloe-emodin (AE), an ingredient of aloe, is known to exhibit anti-inflammatory activities. However, little is known about the underlying molecular mechanisms of its inflammatory modulatory activity in vitro. In the present study, we investigated the anti-inflammatory potential of AE using $Pam_3CSK_4$-stimulated macrophages. Methods: RAW 264.7 macrophages were treated with AE (0~20 mM) for 1 h, followed by treatment with $Pam_3CSK_4$ for 1 h. After incubation, mRNA expression levels of cytokines were measured. The effect of AE on TLR2-related molecules was also investigated in $Pam_3CSK_4$-stimulated RAW 264.7 macrophages. Results: AE attenuated $Pam_3CSK_4$-stimulated expression of proinflammatory cytokines, including tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin-6 (IL-6), and interleukin-$1{\beta}$ ($IL-1{\beta}$) in RAW 264.7 macrophages. Two concentrations of AE ($10{\mu}M$ and $20{\mu}M$) effectively reduced mRNA expression of TLR2 by 41.18% and 54.43%, respectively, compared to that in control cells (p < 0.05). AE also decreased nuclear factor-kappa B ($NF-{\kappa}B$) activation and mitogen-activated protein kinase (MAPK) phosphorylation. Phosphorylation levels of ERK1/2, p38, and JNK were markedly reduced by $20{\mu}M$ AE. In particular, AE decreased phosphorylation of ERK in a dose-dependent manner in $Pam_3CSK_4$-stimulated RAW 264.7 macrophages. Conclusion: Our data indicate that AE exerts its anti-inflammatory effect by suppressing TLR2-mediated activation of $NF-{\kappa}B$ and MAPK signaling pathways in macrophages.

Design of a 64×64-Bit Modified Booth Multiplier Using Current-Mode CMOS Quarternary Logic Circuits (전류모드 CMOS 4치 논리회로를 이용한 64×64-비트 변형된 Booth 곱셈기 설계)

  • Kim, Jeong-Beom
    • The KIPS Transactions:PartA
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    • v.14A no.4
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    • pp.203-208
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    • 2007
  • This paper proposes a $64{\times}64$ Modified Booth multiplier using CMOS multi-valued logic circuits. The multiplier based on the radix-4 algorithm is designed with current mode CMOS quaternary logic circuits. Designed multiplier is reduced the transistor count by 64.4% compared with the voltage mode binary multiplier. The multiplier is designed with Samsung $0.35{\mu}m$ standard CMOS process at a 3.3V supply voltage and unit current $5{\mu}m$. The validity and effectiveness are verified through the HSPICE simulation. The voltage mode binary multiplier is achieved the occupied area of $7.5{\times}9.4mm^2$, the maximum propagation delay time of 9.8ns and the average power consumption of 45.2mW. This multiplier is achieved the maximum propagation delay time of 11.9ns and the average power consumption of 49.7mW. The designed multiplier is reduced the occupied area by 42.5% compared with the voltage mode binary multiplier.