• Journal of Radiation Industry
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• v.17 no.4
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• pp.321-326
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• 2023

Radiopharmaceuticals that need to be transported in a low-temperature state must satisfy both radiation safety and proper temperature maintenance. However, an efficient transport system considering the characteristics of radiopharmaceuticals that require low temperature maintenance has not yet existed. In order to secure a transportation system for the safe and stable transportation of the radiopharmaceutical ¹³¹I mIBG, which requires transportation in cryogenic conditions, we have developed a transportation system that can maintain cryogenic conditions below -60℃ for 6 days while stably fixing the inner container. In addition, by applying a data logger that can simultaneously measure the temperature and the dose of radiation, safety and stability in the transportation process can be secured at the same time. The cryogenic transportation system for ¹³¹I mIBG will be applied to products currently being supplied, and we expect to dramatically improve the management of cold chain radioactive material transportation.

• Bulletin of the Korean Mathematical Society
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• v.51 no.2
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• pp.373-386
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• 2014

Let (R,m) be a commutative Noetherian local ring. In this paper we show that a finitely generated R-module M of dimension d is Cohen-Macaulay if and only if there exists a proper ideal I of R such that depth($M/I^nM$) = d for $n{\gg}0$. Also we show that, if dim(R) = d and $I_1{\subset}\;{\cdots}\;{\subset}I_n$ is a chain of ideals of R such that $R/I_k$ is maximal Cohen-Macaulay for all k, then $n{\leq}{\ell}_R(R/(a_1,{\ldots},a_d)R)$ for every system of parameters $a1,{\ldots},a_d$ of R. Also, in the case where dim(R) = 2, we prove that the ideal transform $D_m(R/p)$ is minimax balanced big Cohen-Macaulay, for every $p{\in}Assh_R$(R), and we give some equivalent conditions for this ideal transform being maximal Cohen-Macaulay.

• Journal of KIISE
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• v.42 no.2
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• pp.272-279
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• 2015

Concurrent with the more widespread usage of smart devices, mobile users' desires are becoming much more complex. Most IT experts insist that smart devices should have additional functions to satisfy these requirements. In particular, research has concentrated on LBS (Locationbased Service), because it is considered one of the most common mobile service types. Generally, Wi-Fi has a critical limitation for use for LBS services, because it requires new network connection points whenever its location (Network Zone) changes. Unfortunately, GPS also has a systematic problem in providing LBS service in the indoor environment, because of its inaccuracy in processing data. So, to redress these limitations, iBeacon technology has been designed, and is currently used for LBS service instead of Wi-Fi or GPS. By using iBeacon, which is based on Bluetooth 4.0 LE technology, we propose a M-SAS (Mobile-Subway-Alarm-Service System) that could accurately and timely provide its users with various mLBS (micro LBS) services, such as current user location, and subway arrival time.

• BMB Reports
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• v.31 no.1
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• pp.77-82
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• 1998

To purify the geranylgeranyl protein transferase type I (GGPT-I) efficiently, a gene expression system using the pGEX-4T-1 vector was constructed. The cal1 gene, encoding the ${\beta}$ subunit of GGPT-I, was subcloned into the pGEX-4T-1 vector and co-transformed into E. coli cells harboring the ram2 gene, the ${\alpha}$ subunit gene of GGPT-I. GGPT-I was highly expressed as a fusion protein with glutathione S-transferase (GST) in E. coli, purified to homogeneity by glutathione-agarose affinity chromatography, and the GST moiety was excised by thrombin treatment. The purified yeast GGPT-I showed a dose-dependent increase in the transferase activity, and its apparent $K_m$ value for an undecapeptide fused with GST (GST-PEP) was $0.66\;{\mu}M$ and the apparent value for geranylgeranyl pyrophosphate (GGPP) was $0.071\;{\mu}M$.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.10 no.2
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• pp.196-206
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• 1999

In this paper, we have estimated the interference effects between the NGSO/MSS system and the fixed-service M/W system for sharing the NGSO/MSS system into the frequency band operated by the existing M/W system. Between above two systems, the interference effects must be analyzed in the following three points. That is, PFD(Power Flux Density) level must be obtained in the case of the interference from NGSO satellites into M/W stations, C/I(Carrier-to-Interference Ratio) and the coordination contour in the case of the interference between NGSO/MSS feeder link and a M/W station, and the interference power level and coordination contour in the case of the interference between NGSO/MSS service link(handsets) and M/W stations. Therefore, in order to obtain above three criteria, we have developed the analytical model, introduced the related equations and estimated the system performance by means of the simulation and the theoretial analysis. It is expected that the results will be utilized in setting the criterion for sharing between the NGSO/MSS system and the M/W station.

• International Journal of Aeronautical and Space Sciences
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• v.15 no.4
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• pp.412-418
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• 2014

This paper describes the development of variable stability system (VSS) control laws for the KFA-i to simulate the dynamics of KFA-m aircraft. The KFA-i is a single engine, Class IV aircraft and was selected as an in-flight simulator (IFS) aircraft, whereas the KFA-m is a simulated aircraft that is based on the F-16 aircraft. A 6-DoF math model of KFA-i aircraft was developed, linearized, and separated into longitudinal and lateral motion for VSS control law synthesis. The KFA-i aircraft has five primary control surfaces: two flaperons, two all movable horizontal tails, and one rudder. Flaperons are used for load control, the horizontal tails are used for pitch and roll rate control, and the rudder is used for yaw rate control. The developed VSS control law can simulate four parameters of the KFA-m aircraft simultaneously, such as pitch, roll, yaw rates, and load. The simulation results show that KFA-i follows the responses of KFA-m with high accuracy.

• Journal of Korean Association for Spatial Structures
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• v.19 no.1
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• pp.53-64
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• 2019

The objective of this study is to investigate the earthquake response for the design of 100m spanned single-layer lattice dome. The plastic hinge analysis and eigenvalue buckling analysis are performed to estimate the ultimate load of single-layered lattice domes under vertical loads. In order to ensure the stability of lattice domes, it is investigated for the plastic hinge progressive status by the pushover increment analysis considering the elasto-plastic connection. One of the most effective methods to reduce the earthquake response of large span domes is to install the LRB isolation system of a dome. The authors discuss the reducing effect for the earthquake dynamic response of 100m spanned single-layered lattice domes. The LRB seismic isolation system can greatly reduce the dynamic response of lattice domes for the horizontal and vertical earthquake ground motion.

• Proceedings of the KIEE Conference
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• 2003.07d
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• pp.2271-2273
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• 2003

Control Rod Control System(CRCS) is to control nuclear reaction of reactor by moving Control Rod Drive Mechanism(CRDM) with speed and direction signal from Reactor Regulating System(RRS). CRCS is made up of two parts : control cabinet and power cabinet. And this paper presents mainly power cabinet design for system reliability. To increase reliability of power cabinet, controller, power supply and communication line arc doubly designed and supervision and diagnosis function are applied.

• International Journal of Reliability and Applications
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• v.3 no.4
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• pp.165-171
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• 2002

An optimization of the M/M/1 queue with impatient customers is studied. The impatient customer does not enter the system if his or her virtual waiting time exceeds the threshold K ＞ 0. After assigning three costs to the system, a cost proportional to the virtual waiting time, a penalty to each impatient customer, and also a penalty to each unit of the idle period of the server, we show that there exists a threshold K which minimizes the long-run average cost per unit time.

• Korean Journal of Veterinary Research
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• v.46 no.2
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• pp.97-105
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• 2006

All-trans retinoic acid (AtRA) induces growth inhibition and apoptosis in a variety of tumer cells, including MCF-7 cells. Insulin-like growth factors (IGFs) system has been reported to be associated with the development of cancer. Although MCF-7 cell with AtRA is to be the major stimulus for the cell growth and apoptosis, the mechanism of insulin-like growth factor-I (IGF-I)/insulin-like growth factor binding protein-3 (IGFBP-3) system remains to be elucidated. Thus, this study was conducted to the effect of AtRA on the gene expression and level of IGF-I and IGFBP-3. In addition, we investigated the involvement of PKC-${\delta}$ on the IGF-I and IGFBP-3 secretion in MCF-7 cell. AtRA(${\geq}10^{-7}M$) decreased the IGF-1 secretion and mRNA expressions, but increased IGFBP-3 secretion and mRNA expressions in MCF-7 cells. Especially, the treatment of AtRA at 72 hours caused a significant reduction in the IGF-I secretion and mRNA expressions but increment in IGFBP-3 secretion and mRNA expressions (p < 0.05). $10^{-7}M$ AtRA activated PKC-${\delta}$ that is one among PKC-$\iota$, ${\alpha}$, ${\lambda}$ and ${\delta}$ in MCF-7 cell. Rotllerin, a PKC-${\delta}$ inhibitor, blocked AtRA-induced inhibition of the IGF-I and mRNA expressions, and increase of lGFBP-3 and mRNA expressions in MCF-7 cell. Together, AtRA inhibited the IGF-I secretion and mRNA expressions, but increased IGFBP-3 secretion and mRNA expressions in MCF-7 cell. Furthermore, AtRA-induced alteration of IGF-I, IGFBP-3 secretion, and the gene expressions were mediated via PKC-${\delta}$ activity.