• Biomolecules & Therapeutics
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• v.8 no.2
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• pp.119-124
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• 2000

We hypothesized that the extent of hypoxic injury would be involved in reduction of oxygen delivery to the tissue. Livers isolated from 18 hr-fasted rats were subjected to $N_2$-induced hypoxia or low flow hypoxia. Livers were perfused with nitrogen/carbon dioxide gas for 45min or perfused with normoxic Krebs-Henseleit bicarbonate buffer (KHBB) at low flow rates around 1 ml/g liver/min far 45min, which caused cells to become hypoxic because of insufficient delivery of oxygen. When normal flow rates(4 ml/g liver/min) of KHBB (pH 7.4, 37$^{\circ}C$, oxygen/carbon dioxide gas) were restored for 30min reoxygenation injury occurred. Lactate dehydrogenase release gradually increased in $N_2$-induced hypoxia, whereas it rapidly increased in low flow hypoxia. Total glutathione in liver tissue was not changed but oxidized glutathione markedly increased after hypoxia and reoxygenation, expecially in $N_2$-induced hypoxia. Similarly, lipid peroxidation in liver tissue significantly increased after hypoxia and reoxygenation in low flow hypoxia. Hepatic drug metabolizing functions (phase I, II) were suppressed during hypoxia, especially in $N_2$-induced hypoxia but improved by reoxygenation in both models. Our findings suggest that hypoxia results in abnormalities in drug metabolizing function caused by oxidative stress and that this injury is dependent on hypoxic conditions.

• Journal of computational fluids engineering
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• v.15 no.2
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• pp.55-61
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• 2010

A dependence of weighting parameter in preconditioning method for solving low Mach number flow with incompressible flow nature is investigated. The present preconditioning method employs a finite-difference method applied Roe‘s flux difference splitting approximation with the MUSCL-TVD scheme and 4th-order Runge-Kutta method in curvilinear coordinates. From the computational results of benchmark flows through a 2-D backward-facing step duct it is confirmed that there exists a suitable value of the weighting parameter for accurate and stable computation. A useful method to determine the weighting parameter is introduced. With this method, high accuracy and stable computational results were obtained for the flow with low Mach number in the range of Mach number less than 0.3.

• 한국전산유체공학회:학술대회논문집
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• 2009.11a
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• pp.159-163
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• 2009

In this paper, the fluid dynamic forces and performances of a moving airfoil in the low Reynolds number flow is addressed. In order to calculate the necessary propulsive force for the moving airfoil in a low Reynolds number flow, a lattice-Boltzmann method is used. The critical Reynolds and Strouhal numbers for the thrust generation are investigated for the four propulsion types. It was found that the Normal P&D type produces the largest thrust with highest efficiency among the investigated types. The leading edge of the airfoil has an effect of deciding the force production types, whereas the trailing edge of the airfoil plays an important role in augmenting or reducing the instability produced by the leading edge oscillation. It is believed that present results can be used to decide the optimal propulsion devices for the given Reynolds number flow.

• 한국연소학회:학술대회논문집
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• 2001.11a
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• pp.17-26
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• 2001

Self flue gas recirculation flow is an effective method for low NOx emission in the regenerative low NOx burner. The object of this study is to analyze the self flue gas recirculating flow by varying jet velocity of the combustion air. Fuel and air flow rates are fixed and combustion air jet nozzle diameters are 13, 6.5 and 5mm. The stoichiometric line is obtained from the concentration of the fuel using an acetone PLIF technique. It is found that the self flue gas recirculating flow is entrained into that line using a two color PIV technique. As the jet velocity of combustion air is increased, the flue gas entrainment rate into the stoichiometric line is increased. This result suggests that NOx emission can be reduced due to the effects of flue gas which is lowering the flame temperatures.

• Proceedings of the Korean Nuclear Society Conference
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• 1995.10a
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• pp.315-320
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• 1995

The CHF phenomenon has been investigated for water flow under forced and natural circulation modes with vertical round tubes at low pressure and low flow condition. Experiments have been performed by using three different test sections for mass fluxes below 400 kg/㎡s under near atmospheric pressure. The experimental data for forced and natural circulation are compared with each other. To predict the flow rate at the two-phase region our test condition has been analyzed by RELAP5/MOD3 because the local two-phase condition inside the stainless steel tube cannot be directly measured. To predict the CHF with accuracy we have to consider the parameters at the single-phase region as well as the flow behavior at the two-phase region.

• Journal of the Korean Society of Combustion
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• v.6 no.1
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• pp.20-28
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• 2001

Self flue gas recirculation flow is an effective method for low NOx emission in a regenerative low NOx burner. The object of this study is to analyze self flue gas recirculating flow by varying the jet velocity of the combustion air. Fuel and air flow rates are fixed and combustion air jet nozzle diameters are 13, 6.5 and 5mm. The stoichiometric line is obtained from the concentration of fuel using the acetone PLIF technique. It is found that self flue gas recirculating flow is entrained into that line using the two color PIV technique. As the jet velocity of combustion air is increased, the flue gas entrainment rate into the stoichiometric line is increased. This result suggests that NOx emission can be reduced due to the effects of flue gas lowering the flame temperature.

• Journal of Korea Water Resources Association
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• v.32 no.3
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• pp.265-279
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• 1999

In this study, one of the techniques on the extension of low flow series has been developed, in which the daily streamflows were simulated by the Tank model with the input of extended daily rainfall series which were stochastically generated by the Markov chain model. The annual lowest flow serried for each of the given durations were formulated form the simulated daily streamflow sequences. The frequency of the estimated annual lowest flow series was analyzed. The distribution types to be used for the frequency analysis were two-parameter and three-parameter log-normal distribution, two-parameter and three-parameter Gamma distribution, three-parameter log-Gamma distribution, Gumbel distribution, and Weibull distribution, of which parameters were estimated by the moment method and the maximum likelihood method. The goodness-of-fit test for probability distribution is evaluated by the Kolmogorov-Sminrov test. The fitted distribution function for each duration series is applied to frequency analysis for developing duration-low flow-frequency curves at Yongdam Dam station. It was shown that the purposed technique in this study is available to generate the daily streamflow series with fair accuracy and useful to determine the probabilistic low flow in the watersheds having the poor historic records of low flow series.

• Transactions of Materials Processing
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• v.23 no.2
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• pp.116-121
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• 2014

Low pressure die casting and flow forming have been successfully used to produce sound road wheels from magnesium alloy AM80. In the current study, high speed compression testing was initially conducted to simulate the flow forming of a Mg wheel. Subsequently the flow forming was simulated with "Forge$^{TM}$", an FEM software package. On the basis of flow forming simulations, the flow forming of the Mg wheel was performed under different conditions. For the flow forming experiments, the preform castings were made by low pressure die casting from AM80, a commercial magnesium alloy. In flow forming of the magnesium preform wheel, the flow forming of the Mg wheel was successfully accomplished when the feed rate was less than half that for the forming of an aluminum road wheel. The reduction in feed rate was 52%. Finally, a comparison with the flow forming simulations was made.

• Nuclear Engineering and Technology
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• v.37 no.5
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• pp.457-468
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• 2005

An experimental study on post-CHF heat transfer has been performed with a $3\times3$ rod bundle using a vertical steam-water two-phase flow at low flow conditions. The effects of various parameters on the post-CHF heat transfer are investigated and the reasons for the parametric effects are discussed. As the heat transfer regime changes from CHF to post-CHF, the radial wall temperature distribution is changed depending on the pressure and the mass flux conditions. The superheat of the fluid increases considerably with an increase of the wall temperature (or heat flux) and with a decrease of the mass flux. This implies, indirectly, a strong thermal non-equilibrium at high wall temperature and low mass flux conditions. In order to improve the prediction accuracy of the existing post-CHF correlations, it is necessary to perform more experiments, particularly direct measurement of the vapor superheat, and to modify the correlation by considering a strong thermal non-equilibrium at low flow and low pressure conditions.

• 한국전산유체공학회:학술대회논문집
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• 2004.03a
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• pp.172-177
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• 2004

In the present work, we have interests on the modification of parallel implemented with MPI(Message Passing Interface) programming method, 3-Dimensional, unsteady, incompressible Navier-Stokes equation solver to analyze the low-Reynolds number flow In order to accurate calculation aerodynamic coefficients in low-Reynolds number flow field, we modified the two-equation turbulence model. This paper describes the development and validation of a new two-equation model for the prediction of flow transition. It is based on Mentor's low Reynolds $\kappa-\omega$ model with modifications to include Total Stresses Limitation (TSL) and Separation Transition Trigger (STT)