Yoon, Songyi;Choi, Jae-Wook;Lee, Eunil;Ahn, Hyongjin;Choi, Hyong Doo;Kim, Nam
Environmental Analysis Health and Toxicology
/
v.30
/
pp.15.1-15.11
/
2015
Objectives There has been a growing concern about the possible carcinogenic effects of the electromagnetic radiofrequency fields emitted from mobile phones. The purpose of this study was to investigate the association between mobile phone use and the development of gliomas in Korea. Methods Our study methods were based on the International Interphone study that aimed to evaluate possible adverse effects of mobile phone use. This study included 285 histologically-confirmed Korean patients 15 to 69 years of age, with gliomas diagnosed between 2002 and 2007 in 9 hospitals. The 285 individually matched controls were healthy individuals that had their medical check-up in the same hospitals. Unconditional logistic regression was used to calculate the adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for use of mobile phones. Results For the entire group, no significant relationship was investigated between gliomas and regular use of mobile phones, types of mobile phones, lifetime years of use, monthly service fee, and the other exposure indices. Analyses restricted to self-respondents showed similar results. For ipsilateral users, whose the body side for usual mobile phone use match the location of glioma, the aORs (95% CIs) for lifetime years of use and cumulative hours of use were 1.25 (0.55 to 2.88) and 1.77 (0.32 to 1.84), respectively. However, the contralateral users showed slightly lower risk than ipsilateral users. Conclusions Our results do not support the hypothesis that the use of mobile phones increases the risk of glioma; however, we found a non-significant increase in risk among ipsilateral users. These findings suggest further evaluation for glioma risk among longterm mobile phone users.
Kim, Younghwan;Choi, Sooyoung;Lee, Kija;Han, Woosok;Choi, Hojung;Lee, Youngwon
Journal of Veterinary Clinics
/
v.33
no.1
/
pp.10-15
/
2016
The purpose of this study was to establish reproducible ischemic infarction model using allogenic blood clot in beagle dogs and identify induced ischemic lesion after middle cerebral artery occlusion using magnetic resonance imaging (MRI) and histopathologic findings. Twenty eight male beagle dogs with no evidence of neurologic disease were experimented. Allogenic embolus was made using a healthy beagle dog. After internal carotid artery (ICA) was exposure, 16G catheter was introduced through the ICA. The dog was administered 0.3 ml blood clot for 15 seconds followed by 3 ml of saline for 15 seconds. MRI scans were performed with 1.5T to evaluate ischemic lesion at 7 days after middle cerebral artery occlusion procedure. Evaluation parameters of MRI include location, distribution, infarction type, margin, shape, mass effect and intensity of T1-weighted imaging (T1WI), T2-weighted imaging (T2WI), fluid attenuated inversion recovery (FLAIR) sequence, diffusion weighted imaging (DWI) and apparent diffusion coefficient (ADC). On MRI, all dogs (28/28) showed focal or multifocal lesion including telencephalon and thalamus lesions, especially caudate nucleus (24/28). These lesions had well-defined margin from adjacent brain parenchyma, none or mild mass effect and various shape. Most of dogs appeared hyperintensity on T1WI, T2WI, FLAIR, and DWI/ADC, corresponding to chronic infarction. These lesions were histopathologically confirmed atrophic changes and unstained lesion. In conclusion, MRI is the useful method to provide information about ischemic infarction in dogs and the best reproducible ischemic infarction model was developed by using allogenic blood clot.
Journal of the Architectural Institute of Korea Planning & Design
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v.34
no.11
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pp.145-156
/
2018
Urban campus, one of the main urban facilities, is the representative place that is struggling with 'gridlock'. Due to privatization of space among different departments and space shortages, gridlock has been occurring as a result. The urban campus trying to solve this problem by changing the quality of space, especially the structure of the shared space, which is expected to be the solution to the grid lock problem. The main purpose of this study is to investigate the structural change in the university's shared space based on paradigm transition. The theoretical consideration is to analyze the spatial characteristics of university shared space that appear at different stages through a new perspective that compares the gridlock phenomenon and the shared paradigm. The framework of the analysis of the shared space, which has recently been restructured, is classified into the spatial characteristics of collaborative space, the creative space, and the common/complex space. In addition, these spatial characteristics are again analyzed through the division of legislative facility classification, management governance subject, area, building location and layout, exposure to the outside as well as the analysis of student and staff entry and exit, sharing structure of site and space, and the classification of program characteristics. The results are as follows: The restructured space is systemized so that the management governance of each space would be connected to each other to share information and space. Furthermore, the spatial boundary between colleges or between campus spaces are not only physically, but categorically clear. The restructured space has semi (or in-between)-spatial characteristics such as the intersection in inside and outside of the pedestrian's circulation and the mixture of programs. This study could serve as principal references in presenting the systematic analysis of directions of the shared spatial structure for the urban campus where new educational space is required due to the changes in the university system.
Sojung Kim;Han Hong Lee;Kyo Young Song;Ho Seok Seo
Journal of Gastric Cancer
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v.24
no.2
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pp.185-198
/
2024
Purpose: Peritoneal washing cytology (PWC) is a widely used diagnostic tool for detecting peritoneal metastasis of advanced gastric cancer. However, the prognosis of patients with positive PWC remains poor even after gastrectomy, and treatments vary among institutions and eras. In this study, we identified the clinical factors that can help predict cytology-positive (CY(+)) gastric cancer. Materials and Methods: We retrospectively reviewed the national data of patients with gastric cancer from 2019, as provided by the Information Committee of the Korean Gastric Cancer Association. Of the 13,447 patients with gastric cancer, 3,672 underwent PWC. Based on cytology results, we analyzed the clinicopathological characteristics and assessed the possibility of CY(+) outcomes in relation to T and N stages. Results: Of the 3,270 patients who underwent PWC without preoperative chemotherapy, 325 were CY(+), whereas 2,945 were negative. CY(+) was more commonly observed in patients with Borrmann type IV gastric cancer, an undifferentiated histological type, and advanced pathological stages. Multivariate analysis revealed Borrmann type IV (odds ratio [OR], 1.821), tumor invasion to T3-4 (OR, 2.041), and lymph node metastasis (OR, 3.155) as independent predictors of CY(+). Furthermore, for circular tumor location, the N stage emerged as a significant risk factor for CY(+), particularly when the tumor was located on the posterior wall (PW) side. Conclusions: Lymph node metastasis significantly affects CY(+) outcomes, particularly when the tumor is located on the PW side. Therefore, PWC should be considered not only in suspected serosal exposure cases but also in cases of lymph node metastasis.
Kim, Tae-Ho;Kim, Kyung-Ho;Han, Yunsang;Lee, Seok-Han;Choi, Jong-Soo
Journal of the Institute of Electronics and Information Engineers
/
v.51
no.2
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pp.55-68
/
2014
Some infrastructure these days is usually constructed under the ground for it to not interfere the foot-traffic of pedestrians, and thus, it is difficult to visually confirm the accurate location of the site where the establishments must be buried. These technical difficulties increase the magnitude of the problems that could arise from over-reliance on the experience of the worker or a mere blueprint. Such problems include exposure to flood and collapse. This paper proposes a constructor-oriented visualization system via mobile gadgets in general construction sites with occluded structures. This proposal is consisted with three stages. First, "Stage of detecting manhole and extracting features" detects and extracts the basis point of occluded structures which is unoccluded manhole. Next, "Stage of tracking features" tracks down the extracted features in the previous stage. Lastly, "Stage of visualizing occluded constructions" analyzes and synthesizes the GPS data and 3D objects obtained from mobile gadgets in the previous stages. This proposal implemented ideal method through parallel analysis of manhole detection, feature extraction, and tracking techniques in indoor environment, and confirmed the possibility through occluded water-pipe augmentation in real environment. Also, it offers a practical constructor-oriented environment derived from the augmented 3D results of occluded water-pipings.
Journal of the Institute of Electronics and Information Engineers
/
v.54
no.3
/
pp.97-107
/
2017
In the field of automatic door, the infrared rays and microwave sensor are much used as the important components in charge of the motor's operation control of open and close through the incoming signal of object recognition. In case of existing system that the sensor of the infrared rays and microwave are applied to the automatic door, there are many malfunctions by the infrared rays and visible rays of the sun. Because the automatic doors are usually installed outside of building in state of exposure. The environmental change by temperature difference occurs the noise of object recognition detection signal. With this problem, the hardware fault that the detection sensor is unable to follow the object moving rapidly within detection area makes the sensing blind spot. This fault should be improved as soon as possible. Because It influences safety of passengers who use the automatic doors. This paper conducted an experiment to improve the detection area by installing extra ultrasonic sensor besides existing detection sensor. So, this paper realize the computing circuit and detection algorithm which can correctly and rapidly process the access route of objects moving fast and the location area of fixed obstacles by applying detection and advantages of ultrasonic signal to the automatic doors. With this, It is proved that the automatic door applying ultrasonic sensor is improved detection area of blind spot sensing through field test and improvement plan is proposed.
When using Image Guided Radiation Therapy, the patient is placed using skin marker first and after confirming anatomical location using OBI, the couch is moved to correct the set up. Evaluation for the error made at that moment was done. Through comparing $0^{\circ}$ and $270^{\circ}$ direction DRR image and OBI image with 2D-2D matching when therapy planning, comparison between patient's therapy plan setup and actual treatment setup was made to observe the error. Treatment confirmation on important organs such as head, neck and spinal cord was done every time through OBI setup and other organs such as chest, abdomen and pelvis was done 2 ~ 3 times a week. But corrections were all recorded on OIS so that evaluation on accuracy could be made through using skin index which was divided into head, neck, chest and abdomen-pelvis on 160 patients. Average setup error for head and neck patient on each AP, SI, RL direction was $0.2{\pm}0.2cm$, $-0.1{\pm}0.1cm$, $-0.2{\pm}0.0cm$, chest patient was $-0.5{\pm}0.1cm$, $0.3{\pm}0.3cm$, $0.4{\pm}0.2cm$, and abdomen was $0.4{\pm}0.4cm$, $-0.5{\pm}0.1cm$, $-0.4{\pm}0.1cm$. In case of pelvis, it was $0.5{\pm}0.3cm$, $0.8{\pm}0.4cm$, $-0.3{\pm}0.2cm$. In rigid body parts such as head and neck showed lesser setup error compared to chest and abdomen. Error was greater on chest in horizontal axis and in AP direction, abdomen-pelvis showed greater error. Error was greater on chest in horizontal axis because of the curve in patient's body when the setup is made. Error was greater on abdomen in AP direction because of the change in front and back location due to breathing of patient. There was no systematic error on patient setup system. Since OBI confirms the anatomical location, when focus is located on the skin, it is more precise to use skin marker to setup. When compared with 3D-3D conformation, although 2D-2D conformation can't find out the rolling error, it has lesser radiation exposure and shorter setup confirmation time. Therefore, on actual clinic, 2D-2D conformation is more appropriate.
Asia-Pacific Journal of Business Venturing and Entrepreneurship
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v.18
no.4
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pp.207-222
/
2023
In order to improve employment rates, most universities operate programs to strengthen students' employment and entrepreneurship, regardless of whether they are selected as the Leading Industry-Innovative University (LINC) or not. In particular, in the case of non-metropolitan universities are risking their lives to improve employment rates. In order to overcome the limitations of university establishment type and university location, which absolutely affect the employment rate, we are operating a startup education & startup support program in order to strengthen employment and entrepreneurship, and capstone design & field training as industry-academia-linked education programs are always available. Although there are studies on effectiveness verification centered on LINC (Leaders in Industry-University Cooperation) in previous studies, but a longitudinal study was conducted on all factors of university factors, startup education & startup support, and capstone design & field training as industry-university-linked education programs as factors affecting the employment rate based on public disclosure indicators. No cases of longitudinal studies were reported. This study targets 116 universities that satisfy the conditions based on university disclosure indicators from 2018 to 2020 that were recently released on university factors, startup education & startup support, and capstone design & field training as industry-academia-linked education programs as factors affecting the employment rate. We analyzed the differences between the LINC (Leaders in Industry-University Cooperation) 51 participating universities and 64 non-participating universities. In addition, considering that there is no historical information on the overlapping participation of participating students due to the limitations of public indicators, the Exposure Effect theory states that long-term exposure to employment and entrepreneurship competency enhancement programs will affect the employment rate through competency enhancement. Based on this, the effectiveness of the 2nd LINC+ (socially customized Leaders in Industry-University Cooperation) was verified from 2017 to 2021 through a longitudinal causal relationship analysis. As a result of the study, it was found that the startup education & startup support and capstone design & field training as industry-academia-linked education programs of the 2nd LINC+ (socially customized Leaders in Industry-University Cooperation) did not affect the employment rate. As a result of the longitudinal causal relationship analysis, it was reconfirmed that universities in metropolitan areas still have higher employment rates than universities in non-metropolitan areas due to existing university factors, and that private universities have higher employment rates than national universities. Among employment and entrepreneurship competency strengthening programs, the number of people who complete entrepreneurship courses, the number of people who complete capstone design, the amount of capstone design payment, and the number of dedicated faculty members partially affect the employment rate by year, while field training has no effect at all by year. It was confirmed that long-term exposure to the entrepreneurship capacity building program did not affect the employment rate. Therefore, it was reconfirmed that in order to improve the employment rate of universities, the limitations of non-metropolitan areas and national and public universities must be overcome. To overcome this, as a program to strengthen employment and entrepreneurship capabilities, it is important to strengthen entrepreneurship through participation in entrepreneurship lectures and actively introduce and be confident in the capstone design program that strengthens the concept of PBL (Problem Based Learning), and the field training program improves the employment rate. In order for actually field training affect of the employment rate, it is necessary to proceed with a substantial program through reorganization of the overall academic system and organization.
Journal of Korean Society of Occupational and Environmental Hygiene
/
v.24
no.4
/
pp.518-527
/
2014
Objectives: The adverse health effects attributed to exposure to radon have been well known over the world. However, the efforts for prevention and mitigation of radon have not been taken in Korea so far. The purpose of this study was to evaluate the effectiveness of mitigation methods applied for various types of houses and public buildings with high level of radon. Methods: Based on the results of "National Radon Survey" performed by the National Institute of Environmental Research(NIER) in 2010-2012, we selected 30 candidate buildings consisting of 20 houses and 10 public buildings with greater than $148Bq/m^3$ of radon level. We measured the concentration of radon in 30 buildings, using E-PERMs and RAD-7 during January to March of 2013. More than five E-PERMs and one RAD-7 per house were installed for seven days. Ten houses and five public buildings were finally chosen to be mitigated after mainly considering the level of radon and the location of buildings nationwide. Three mitigation methods such as Sealing, two types of Active Ventilation(window-shaped and wall-typed ventilations), and Active Soil Depressurization(ASD) were applied, and the concentrations of radon were measured before and after mitigation, respectively. To evaluate the effectiveness of mitigation methods, reduction rates of radon were calculated and Wilcoxon's signed-rank test was performed. Results: The mean concentration of 15 buildings just before radon mitigation was $297.8Bq/m^3$, and most of the buildings were located in Gangwon, Chungbuk, Chungnam, and Daegu areas(73.3%), and built in 1959-1998. The level of radon decreased from 48% to 90% and kept the below recommendation limit of $148Bq/m^3$ after installation of radon mitigation. Among mitigation methods applied, the reduction rate(58.7-90.4%) of radon attributed to ASD was the greatest than that of other methods, followed by Active Ventilation(48.4-78.4%) and Sealing(<22%). The effectiveness of radon reduction by window-shaped Active Ventilation(63.2-75.2%) was relatively better than that of wall-typed Active Ventilation(48.4-54.3%). Conclusions: The results of this study indicate that ASD could be more effective for radon mitigation. Moreover, our findings would be background information in future for making the strategy for radon mitigation nationwide, as well as for developing Korean-version of mitigation techniques according to types of dwellings in Korea.
Gamma irradiator is widely used for cell, animal experiment, irradiation for blood, dose measurement, and education. Biobeam8000 gamma irradiator (STS Steuerungstechnik &. Strahlenschutz GmbH, Braunschweig, Germany, Cs137, 81.4 TBq) that KIRAMS (Korea Institute of Radiological and Medical Science) has is a irradiation device that enables to be used in large-capacity of 7.5 L and extensive area. Cs-137 source moves range of 24 cm back-and-forth in a regular cycle in beaker for uniform irradiation and a beaker that puts a specimen like existing radiation irradiator such as Gammacell3000 rotates $360^{\circ}$ during irradiation. Precise dose information according to the location of radiation source would be needed because of the movement of radiation source, whereas radiation could be uniformly irradiated in comparison with existing gamma irradiator. In this study, dose distribution of the inside beaker located in Biomeam8000 gamma irradiator was measured using glass dosimeter, and dose evaluation and distribution regarding dose linearity and dose reproducibility were implemented based on measurement results. This aims to show guideline for efficient use of irradiator based on measurement result when doing experiment or radiation exposure.
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