• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1205-1210
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• 2014

Background: Previous studies on the association of oral contraceptives (OC) use and lung cancer generated inconsistent findings. The aim of this study was to confirm any definite correlation between OC use and lung cancer risk. Methods: Publications were reviewed and obtained through PubMed and EMBASE databases literature search up to November, 2013. Reference lists from retrieved articles were also reviewed. The language of publication was restricted to English. A meta-analysis was performed to evaluate the association by calculating pooled odds ratios (ORs) and 95% confidence intervals (CIs). Results: A total of 14 studies consisting of 9 case-control studies and 5 cohort studies were finally included in this meta-analysis. There was no significant association observed between OC use and lung cancer risk in the overall analysis (OR=0.91; 95% CI=0.81-1.03). There was a significant protective effect in Europe (OR=0.74; 95% CI=0.60-0.91) and a borderline significant protective effect with an adenocarcinoma histology (OR=0.90; 95% CI=0.80-1.01) in subgroup analyses. No association was observed for methodological quality of study, study design, smoking status and case number of study. Conclusion: This meta-analysis suggests that OC use is not likely to be associated with the risk of lung cancer at all. While a significant protective effect of OC use on lung cancer was observed in Europe, interpretation should be cautious because of the potential biases of low-quality studies. At the same time, more attention should be paid to the possible association of OC use with adenocarcinoma of lung. Our findings require further research, with well-conducted and large-scale epidemiological studies to confirm effects of OC use on lung cancer.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.6
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• pp.2857-2861
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• 2014

More and more evidence indicates that the G801A polymorphism in the CXCL12 gene might be associated with susceptibility to breast carcinoma in humans being. However, individually published results have been inconsistent. The purpose of this meta-analysis was to investigate the association between the G801A polymorphism in the CXCL12 gene and breast carcinoma risk. A complete search strategy was done by the electronic databases including PubMed and Chinese Biomedical Literature Database. A meta-analysis including seven individual studies was carried out in order to explore the association between the G801A polymorphism in the CXCL12 gene polymorphisms and breast carcinoma. The pooled odds ratios (ORs) and their corresponding 95% confidence intervals (95%CIs) between the G801A polymorphism in the CXCL12 gene and breast carcinoma risk were assessed by the random-effects model. A significant relationship between the G801A polymorphism in the CXCL12 gene and breast carcinoma was discovered in an allelic genetic model (OR: 1.214, 95%CI: 1.085-1.358, p=0.001), a homozygote model (OR: 1.663, 95%CI: 1.240-2.232, p=0.001), a heterozygote model (OR: 1.392, 95%CI: 1.190-1.629, p=0.000), a recessive genetic model (OR: 1.407, 95%CI: 1.060-1.868, p=0.018) and a dominant genetic model (OR: 1.427, 95%CI: 1.228-1.659, p=0.000). On sub-group analysis based on ethnicity, significance was observed between the European group and the mixed group. A significant relationship was found between the G801A polymorphism in the CXCL12 gene and breast carcinoma risk. Individuals with the A allele of the G801A polymorphism in the CXCL12 gene are under a higher risk for breast carcinoma.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1263-1267
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• 2014

Background: Matrix metalloproteinases (MMPs) play important roles in pathogenesis and development of cancer. Recently, many studies have show associations between polymorphisms in the promoter regions of MMPs and risk of gastric cancer. The present meta-analysis was conducted in order to investigate the potential association between four polymorphisms in the MMP gene and gastric cancer risk. Methods: A computerized literature search was conducted in databases of Med-line, Embase, Science Citation Index and PubMed till June 2013 for any MMP genetic association study of gastric cancer. Odds ratios (ORs) and 95 % confidence intervals (CIs) were estimated for each gene under dominant and recessive models, and heterogeneity between studies was assessed using the Q test and $I^2$ value. Overall and subgroup analyses according to ethnicity were carried out with Stata 12.0. Results: 14 reports covering 8,146 patients (2,980 in the case group and 5,166 in the control group) were included in the present meta-analysis. We found that the MMP-7 (-181A>G) polymorphism increased the gastric cancer risk in therecessive model (GG vs. AA/AG, OR=1.768, 95% CI =1.153-2.712). For MMP2 -1306 C>T, MMP1-1607 1G/2G, and MMP9-1 562 C>T, there were no associations between these polymorphisms and the risk of gastric cancer under dominant or recessive models. Conclusion: This meta-analysis suggested that the MMP7-181 A>G polymorphism may contribute to gastric cancer susceptibility. More studies are needed, especially in Europeans, in the future.

• Journal of Microbiology and Biotechnology
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• v.27 no.6
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• pp.1039-1052
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• 2017

Endophytic fungi have currently been acknowledged as the most promising source of bioactive compounds for drug discovery, and considerable progress has been made in exploring their diversity, species richness, and bioprospecting. Fungal endophytes from unique environmental settings offer a pool of potentially useful medicinal entities. Owing to the constant stresses imposed on macroalgae by marine environments, it is believed that algae and their associated endophytic symbionts represent a good source of structurally diverse bioactive secondary metabolites. Despite the proven significance of active metabolites of algal endophytes, little have been exploited. This review highlights the latest discoveries in algicolous endophytic research, with particular focus on the bioactive metabolites from algal endophytes. Compounds are classified according to their reported biological activities, like anticancer, antibacterial, antifungal, and antioxidant properties. Present experimental evidence suggests that a majority of the bioactive metabolites were reported from Phaeophyceae followed by Rhodophyceae and Chlorophyceae. An intensive search for newer and more effective bioactive metabolites has generated a treasure trove of publications, and this review partially covers the literature published up to 2016.

• Journal of the Korean Society for information Management
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• v.25 no.2
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• pp.127-141
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• 2008

In this study, we investigated the information users' needs and information seeking behavior in the field of science and technology. We found that the science and technology researchers most frequently needed information while conducting the research & development related tasks and drafting research papers. The researchers attributed the main sources of research ideas to be the communication among colleagues and the literature review. The researchers's most preferred information sources were digital libraries, web search engines, and academic information portal. In conclusion, the science and technology researchers regarded the online use of electronic materials as the primary source of information. We hope that this investigation reported herein to be the foundation for developing user-centered information services for the science and technology discipline.

• Journal of the Korean Society for information Management
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• v.37 no.3
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• pp.253-274
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• 2020

In this study, text mining and main path analysis (MPA) were applied to understand the origins and development paths of research areas that make up the mainstream of Korean studies. To this end, a quantitative analysis was attempted based on digital texts rather than the traditional humanities research methodology, and the main paths of Korean studies were extracted by collecting documents related to Korean studies including citation information using a citation database, and establishing a direct citation network. As a result of the main path analysis, two main path clusters (Korean ancient agricultural culture (history, culture, archeology) and Korean acquisition of English (linguistics)) were found in the key-route search for the Humanities field of Korean studies. In the field of Korean Studies Humanities and Social Sciences, four main path clusters were discovered: (1) Korea regional/spatial development, (2) Korean economic development (Economic aid/Soft power), (3) Korean industry (Political economics), and (4) population of Korea (Sex selection) & North Korean economy (Poverty, South-South cooperation).

• Proceedings of the Korea Contents Association Conference
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• 2007.11a
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• pp.107-111
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• 2007

There exists a many-to-many mapping relationship between persons and their names. A person may have multiple names, and different persons may share the same name. These synonymous and homonymous names may severely deteriorate the recall and precision of the person search, respectively. This study addresses the characteristics of features for resolving homonymous author names appearing in citation data. As disambiguation features, previous works have employed citation-internal features such as co-authorship, titles of articles, titles of publications as well as citation-external features such as emails, affiliations, Web evidences. To the best of our knowledge, however, there has been no literature to deal with the influences of features on author disambiguation. This study analyzes the effect of individual features on author resolution using a large-scale test set for Korean.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.50 no.3
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• pp.311-318
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• 2017

Four species of sea turtles (Chelonia mydas, Caretta caretta, Dermochelys coriacea, and Eretmochelys imbricata) have been recorded in Korean waters. However, nationwide surveys on the distribution and occurrence of each species have rarelybeen conducted in Korean waters. In this study, we comparatively analyzed the trends in occurrence of sea turtles and their morphological characteristics based on 148 reliable observations and stuffed specimen data and suggested Korean names for each species. Chelonia mydas (57 cases, 58.8%) and C. caretta (52 cases, 31.5%) were dominant species, and occupied > 90% of all observations. Most of observations of sea turtles in Korean waters were obtained through stranding (61 cases) and incidental catches (62 cases). A coastal set net was the main fishing gear for incidental catches (82%). Sea turtles were found mainly around Jeju-do and the Korea Strait from June to November. Most C. caretta found were adults, whereas most C. mydas were juveniles. Additionally, we provide detailed morphological characteristics of C. mydas (n=8) and C. caretta (n=4) using stuffed specimens. Finally, based on a literature search, we suggest appropriate Korean names, such as "Pureunbada-geobuk" for C. mydas, "Bulgeunbadageobuk" for C. caretta, "Jangsu-geobuk" for D. coriacea, and "Maeburibada-geobuk" for E. imbricate.

• The Journal of the Korea Contents Association
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• v.20 no.9
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• pp.107-128
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• 2020

This study analyzed trends in play therapy for adults in order to search trends in academic research related to play therapy for adults published in Korea. The purpose of this research is to suggest the implications for future research, clinical practice, and education and training. For this study, 73 academic papers published in Korea were selected from 2009 to 2019 on play therapy for adults. As results showed a tendency to expand to various subjects and units while quantitatively growing in a short period of time.

• Journal of Navigation and Port Research
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• v.28 no.10 s.96
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• pp.909-915
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• 2004

This paper suggests an evaluation of risk level for damage of marine accidents in SRRs. Qualitative analyses in words is sometimes priorior to quantative analyses in numeric symbols. This paper introduces a concept of fuzzy theory with the plenty of related literature riview and AHP in the Korean SRRs of RCC and RSC. The methodology of this paper is $max{\cdot}min$ composition of fuzzy extensive principle, defuzzifiation is centroid of gravity methods. At the result, the evaluation of risk level is especially over Serious for marine accident of Busan SRRs. This paper recommends that many Rescue Vessels and Equipments need to the reduction of risk level about those.