• Food Science and Biotechnology
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• 제14권6호
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• pp.854-859
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• 2005

Although action modes of equol and genistein have been extensively studied, their precise roles in tumor cells remain elusive. To address possible effects of these compounds on protein expression in mammary tumor cells, proteins modulated in MCF-7 mammary tumor cells when incubated in absence and presence of 10 uM equol or genistein were identified through 2-dimensional gel electrophoresis, MALDI-TOF MS/MS, and NCBInr database search using Mascot software. Most proteins differentially expressed in MCF-7 cells after treatment with 10 uM genistein or equol were identified as being the same. Exposure to both compounds caused decreased cellular expression of RNA-binding protein regulatory subunit and oncogene DJ1 tubulin beta-1 chain, and increased expression of heterogeneous ribonucleoproteins F and L, KH-type splicing regulatory protein, and translation elongation factor EF-Tu precursor. Genistein and equol at dose used in this study showed common action mechanism.

• 한국광학회지
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• 제11권2호
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• pp.80-84
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• 2000

Diamond turning machine으로 알루미늄을 가공하여 f/1.5, 구경 50mm인 포물명경을 제작하였다. 이진위상(binary phase) 홀로그램으로 포물면경 현상측정을 위한 computer generated hologram(CGH)을 encoding하였으며 staircase encodling 방법으로 간섭무늬 곡선의 직선근사를 하였다. 간섭무늬 데이터를 포스트스크립트(PostScript) 파일로 변환한 후 CGH 원도를 레이저 프린터로 확대 출력하고 축소 촬영하여 CGH를 제작하였다. 측정부(viewing arm)에 CGH가 위치하는 Twyman-Green 간섭계를 구성하여 포물면경의 표면형상을 측정하였다. 측정결과를 직접표면형상측정법 및 간섭계를 이용한 자동시준법의 측정 결과와 비교하고 오치를 분석하였다.

• Structural Engineering and Mechanics
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• 제75권5호
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• pp.621-631
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• 2020

A laboratory experiment is conducted is to investigate the behaviour of a low-mass-ratio and high aspect ratio flexible cylinder under vortex-induced vibration (VIV). A flexible cylinder with aspect ratio of 100 and mass ratio of 1.17 is towed horizontally to generate uniform flow profile. The range of Reynolds number is from 1380 to 13800. Vibration amplitude, in-line and cross-flow frequency response, amplitude trajectory, mean tension variation and hydrodynamic force coefficients are analyzed based on the measurement from strain gauges, load cell and CCD camera. Experimental results indicate that broad-banded lock-in region is found for the cylinder with a small Strouhal number. The frequency switches in the present study indicates the change of the VIV phenomenon. The hydrodynamic force responses provide more understanding on the VIV of a low mass ratio cylinder.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2009년도 춘계 학술발표회
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• pp.38-47
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• 2009

Scour means the erosion of bed material by flow change when a bridge is constructed in a stream. Scour is one of the critical factors of a bridge failure. There are several methods for the monitoring of scour near bridge foundations; Sounding rods, Magnetic sliding collar System, Sonar system, underwater camera system and so on. In general, Sonar system is preferred due to its convenience and good accuracy. In this study, the new scour monitoring system was developed using profiling sonar sensor. The new system can measure a line profile of a seabed and has small size due to the effectively designed data logger. The performance of the new scour monitoring system was evaluated at a bridge pier in tidal environment. The measured local scour depths were discussed with the result of the empirical formulas; CSU, Froehlich, Laursen and Neill.

• 한국레이저가공학회:학술대회논문집
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• 한국레이저가공학회 2005년도 추계학술발표대회 논문집
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• pp.50-56
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• 2005

The robot systems are widely used in the many industrial field as well as welding manufacturing. The essential tasks to operate the welding robot are the acquisition of the position and/or shape of the parent metal. For the seam tracking or the robot tracking, many kinds of contact and non-contact sensors are used. Recently, the vision is most popular. In this paper, the development of the system which measures the shape of the welding part is described. This system uses the line-type structured laser diode and the vision sensor. It includes the correction of radial distortion which is often found in the image taken by the camera with short focal length. The Direct Linear Transformation (DLT) method is used for the camera calibration. The three dimensional shape of the parent metal is obtained after simple linear transformation. Some demos are shown to describe the performance of the developed system.

• Archives of Pharmacal Research
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• 제24권2호
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• pp.159-163
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• 2001

The accelerated stability of dimethoxy biphenyl monocarboxylate.HCl (DDB-S) was investigated in 6 mg/mL water solution in the pH ranging 2-10 and the temperature of $45-85^{\circ}C$. The observed rate of degradation followed first-order kinetics. The energy of activation for DDB-S degradation was calculated to be 14.1 and 16.5 $Kcal/mole$ at pH 5 and in distilled watery respectively. The degradation rate constant ($K_{25^{\circ}C}$) obtained by trending line analysis of Arrhenius plots for DDB-S was $5.3{\times}10^{-6}h^{-1}$. The times to degrade 10% ($t_{10}$) and 50% $t_{500}$) at $K_{25^{\circ}C}$ were 829 and 5,416 days, respectively. DDB-S exhibited the fastest degradation at pH 10 and the slowest rate at pH 5. In addition, at $K_{65^{\circ}C}$, degradation rate constants of DDB-S were 0.066, 0.059, 5.460, 32.171, and $1.4{\times}10^{-6}h^{-1}$ at pH 2, 5, 8, 10 and in distilled water, respectively. These observations indicated that the rate-pH profile of DDB-S showed general acid-base catalysis reaction in the range of pH 2-10.

• Bulletin of the Korean Chemical Society
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• 제25권3호
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• pp.373-376
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• 2004

A novel Er(III) complex with oxydiacetate and 1,10-phenanthroline was synthesized and its structure and luminescence properties were characterized. The complex of $[Er(ODA){\cdot}(phen){\cdot}4H_2O]^+$ crystallizes in the monoclinic space group $P2_1$/n with a = 12.216(4) ${\AA}$, b = 16.680(2) ${\AA}$, c = 12.627(3) ${\AA}$, ${\beta}=108.30(2)^{\circ}$, V = 2442.7(11) ${\AA}^3$, Z = 4 and ${\rho}=1.841 g/cm^3$. When the complex is excited at the He-Cd 325-nm line, it produces two broad bands spanning the regions 350-650 nm and 1200-1650 nm. The emission band of the complex is characterized by a series of spectral dips in the visible emission profile. The complex exhibits sensitized near- IR emission via two kinds of energy transfers from phen to Er(III): nonradiative and radiative energy transfers.

• Journal of the Optical Society of Korea
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• 제12권3호
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• pp.126-130
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• 2008

We propose and experimentally demonstrate an effective method to reduce near-field speckle noise at the output of a 50 ${\mu}m$ graded index multimode fiber using a short cylindrical piezoelectric transducer(PZT) vibrating in the radial direction. The fiber was coiled as tightly as possible around the mandrel of the PZT and a periodic stretching effect was caused by the radial oscillations of the actuator. The output of the optical fiber using the He-Ne laser source was intensively observed by a CCD camera. By counting all the pixels corresponding to relative intensity graded into 256 levels in the selected area and by calculating standard deviation and mean value of the intensity, we could measure the speckle contrast and vibration effect quantitatively with reduction ratio of pixels and line profile of the illuminated region. It was clearly observed that the characteristics of the speckle pattern in the vibration-on state were significantly improved over that of the vibration-off state due to time-averaged smoothing.

• Nuclear Engineering and Technology
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• 제28권1호
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• pp.27-35
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• 1996

본 논문에서는, 가압경수로 발전소의 가압기 밀림관내 비정상상태의 열성층현상에 대한 계산 모델을 제안하여 배관내의 온도분포, 유동특성 및 열응력에 대해 연구하였다. 경계면이 시간에 따라 변화가 없거나 정상상태에서 개발된 다른 모델과는 달리 본 모델에서는 고온 및 저온유체 사이의 경계면을 시간의 함수로 가정하였다. 열성층현상에 대한 무차원지배방정식은 SIMPLE 알고리즘을 사용하여 해를 구하였다. 본 수치계산의 결과는 주어진 조건하에서 무차원시간이 약 27.0 일 때 배관의 고온부 및 저온부사이의 최대무차원온도차는 0.78정도이었고, 이때의 열성층 현상에 의한 최대 열응력은 276 MPa로 계산되었다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제44회 동계 정기학술대회 초록집
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• pp.142-142
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• 2013

DBD (Dielectric Barrier Discharge) 대기압 플라즈마를 이용한 a-Si 식각기술에 대한 연구결과를 논하고자 한다. 기술개발의 목적은 대면적 TFT-LCD 혹은 Flexible Display 공정에 적용가능한 대기압 플라즈마 식각장치의 개발 및 검증이다. 실험에서 식각 가스로는 SF6, NF3 등을 사용하였으며, 질소를 기본 가스로 사용하였다. 검증용으로 개발된 대기압 플라즈마 식각 장치는 대기압 플라즈마 장치를 연속적으로 통과하는 in-line system 형식으로 개발되었다. 검증에 사용된 대기압 플라즈마 장치는 300 mm의 방전 폭으로 1세대 LCD기판의 처리가 가능하다. 대기압 플라즈마 식각 기술 개발에서 식각율에 영향을 미치는 변수들은 기판의 온도, 식각가스의 농도, 기판의 이송속도, 기판과 플라즈마 발생장치 사이의 간격 그리고 플라즈마의 인가 전력 등으로 크게 구분지어 생각할 수 있다. 개발된 식각 장치는 SF6를 사용하는 경우 최대 환산 식각율은 500 nm/min 정도이다. 식각 기술에서 중요한 식각 Uniformity와 그와 연관된 a-Si/SiNx 식각 선택비는 사용하는 가스의 Recipe 개발에 중점을 두고 연구를 진행하였다. 식각 Uniformity는 약 7% 이내의 균일도를 갖고 a-Si/ SiNx의 선택비는 10이상의 결과를 얻었다. 또한 식각 가스는 식각 profile에 영향을 줄 수 있는데 대기압 환경에서 형성되는 collisional sheath에도 불구하고 비 등방성 식각이 가능하였다.