• Wind and Structures
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• v.28 no.2
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• pp.99-110
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• 2019

Vortex-Induced-Vibration (VIV) is one kind of the wind-induced vibrations, which may occur in the construction and operation period of bridges. This phenomenon can bring negative effects to the traffic safety or can cause bridge fatigue damage and should be eliminated or controlled within safe amplitudes.In the current VIV studies, one available mitigation countermeasure, the horizontal flow-isolating plate, shows satisfactory performance particularly in PI shaped bridge deck type. Details of the wind tunnel test are firstly presented to give an overall description of this appendage and its control effect. Then, the computational-fluid-dynamics(CFD) method is introduced to investigate the control mechanism, using two-dimensional Large-Eddy-Simulation to reproduce the VIV process. The Reynolds number of the cases involved in this paper ranges from $1{\times}10^5$ to $3{\times}10^5$, using the width of bridge deck as reference length. A field-filter technique and detailed analysis on wall pressure are used to give an intuitive demonstration of the changes brought by the horizontal flow-isolating plate. Results show that this aerodynamic appendage is equally effective in suppressing vertical and torsional VIV, indicating inspiring application prospect in similar PI shaped bridge decks.

• Journal of Animal Science and Technology
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• v.64 no.3
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• pp.443-461
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• 2022

This study was conducted to assess the effects of the dietary supplementation of riboflavin (as a bile salt hydrolase [BSH] inhibitor) and Bacillus subtilis on growth performance and woody breast of male broilers challenged with Eimeria spp. Intestinal bacteria, including supplemented probiotics, can produce BSH enzymes that deconjugate conjugated bile salts and reduce fat digestion. A 3 × 2 × 2 (riboflavin × Bacillus subtilis × Eimeria spp. challenge) factorial arrangement of treatments in randomized complete block design was used. On d 14, birds were gavaged with 20× doses of commercial cocci vaccine (Coccivac^R -B52, Merck Animal Health, Omaha, NE). Dietary treatment of riboflavin and B. subtilis did not affect body weight (BW), body weight gain (BWG), and feed conversion (FCR) d 0 to 14 and overall d 0 to 41. Eimeria spp challenge reduced BWG, feed intake (FI), and increased FCR between d 14 to 28, but increased BWG and lowered FCR between d 28 to 35. There were no effects of the Eimeria spp. challenge on the overall d 0 to 41 FCR and FI, but BWG was reduced. Eimeria spp. challenge increased the abdominal fat pad weight and slight woody breast incidences on processed birds on d 42. Dietary inclusion of B. subtilis and riboflavin at tested levels did not help birds to mitigate the negative impact of Eimeria spp. challenge to enhance the growth performance.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.9
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• pp.4683-4688
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• 2012

Aim: To investigate the association of transforming growth factor-beta 1 (TGF-${\beta}1$) C-509T polymorphism and susceptibility to cancer by means of meta-analysis. Methods: An extensive search was performed to identify eligible case-control studies investigating such a link. The strength of the association between TGF-${\beta}1$ C-509T polymorphism and cancer risk was assessed by pooled odds ratios (ORs) and 95%confidence intervals (95%CIs) in fixed or random effects models. Results: 55 published case-control studies with a total number of 21,639 cases and 28,460 controls were included. Overall, there was no association between TGF-${\beta}1$ C-509T and cancer risk in all genetic comparison models (TT vs. CC: OR=1.01, 95%CI=0.89-1.15; T vs. C: OR=1.01, 95%CI=0.94-1.07). However, a stratified analysis by cancer type indicated -509 T allele was significantly associated with decreased risk of colorectal cancer (CRC) (TT vs. CT/CC: OR=0.85, 95%CI=0.76-0.95), especially for Caucasians (TT vs. CT/CC: OR=0.83, 95%CI=0.71-0.98) and for population-based studies (TT vs. CT/CC: OR=0.78, 95%CI=0.68-0.89). Conclusion: This meta-analysis suggested that TGF-${\beta}1$ C-509T polymorphism might contribute to a decreased risk on colorectal cancer susceptibility, especially for Caucasians.

• Asian-Australasian Journal of Animal Sciences
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• v.28 no.8
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• pp.1163-1170
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• 2015

Two probiotic strains, Lactobacillus johnsonii x-1d-2 and Lactobacillus mucosae x-4w-1, originally isolated from piglet feces, have been demonstrated to possess antimicrobial activities, antibiotic resistances and interleukin-6 induction ability in RAW 267.4 macrophages in our previous study. These characteristics make L. johnsonii x-1d-2 and L. mucosae x-4w-1 good candidates for application in feed probiotics. In this study, soybeal meal, molasses and sodium acetate were selected to optimize the growth medium for cultivation of L. johnsonii x-1d-2 and L. mucosae x-4w-1. These two strains were then freeze-dried and mixed into the basal diet to feed the weaned piglets. The effects of L. johnsonii x-1d-2 and L. mucosae x-4w-1 on the growth performance and fecal microflora of weaned piglets were investigated. The results showed that the bacterial numbers of L. johnsonii x-1d-2 and L. mucosae x-4w-1 reached a maximum of 8.90 and 9.30 log CFU/mL, respectively, when growing in optimal medium consisting of 5.5% (wt/vol) soybean meal, 1.0% (wt/vol) molasses and 1.0% (wt/vol) sodium acetate. The medium cost was 96% lower than the commercial de Man, Rogosa and Sharpe medium. In a further feeding study, the weaned piglets fed basal diet supplemented with freeze-dried probiotic cultures exhibited higher (p<0.05) body weight gain, feed intake, and gain/feed ratio than weaned piglets fed basal diet. Probiotic feeding also increased the numbers of lactobacilli and decreased the numbers of E. coli in the feces of weaned piglets. This study demonstrates that L. johnsonii x-1d-2 and L. mucosae x-4w-1 have high potential to be used as feed additives in the pig industry.

• Journal of Advanced Navigation Technology
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• v.18 no.1
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• pp.22-28
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• 2014

This paper presents the design and development of ECU simulator in order to verify automatic firmware update system of ECU SW on the vehicle. We designed and developed general-proposed ECU simulator as devide into HW and SW parts. HWadopt 32bit MPU, CAN, LIN, LCD, and touch-pad button to satisfy general-proposed ECU level. And SW constructed as finite-state-machine structure in order to support HW spec. We developed ECU manager which deliveries update data to verify validity of operation. And we tested ECU simulator with ECU manager. For test of validity of ECU simulator, we set 4 scenarios between ECU simulator and manager. As the result, we confirmed validity of operation in ECU simulator for automatic SW update system.

• Annals of Hepato-Biliary-Pancreatic Surgery
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• v.28 no.1
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• pp.1-13
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• 2024

Hepatocellular carcinoma (HCC) is the sixth most diagnosed cancer worldwide. Healthcare resource constraints may predispose treatment delays. We aim to review existing literature on whether delayed treatment results in worse outcomes in HCC. PubMed, Embase, The Cochrane Library, and Scopus were systematically searched from inception till December 2022. Primary outcomes were overall survival (OS) and disease-free survival (DFS). Secondary outcomes included post-treatment mortality, readmission rates, and complications. Fourteen studies with a total of 135,389 patients (delayed n = 25,516, no delay n = 109,873) were included. Age, incidence of male patients, Child-Pugh B cirrhosis, and Barcelona Clinic Liver Cancer Stage 0/A HCC were comparable between delayed and no delay groups. Tumor size was significantly smaller in delayed versus no delay group (mean difference, -0.70 cm; 95% confidence interval [CI]: -1.14, 0.26; p = 0.002). More patients received radiofrequency ablation in delayed versus no delay group (OR, 1.22; 95% CI: 1.16, 1.27; p < 0.0001). OS was comparable between delayed and no delay in HCC treatment (hazard ratio [HR], 1.13; 95% CI: 0.99, 1.29; p = 0.07). Comparable DFS between delayed and no delay groups (HR, 0.99; 95% CI: 0.75, 1.30; p = 0.95) was observed. Subgroup analysis of studies that defined treatment delay as > 90 days showed comparable OS in the delayed group (HR, 1.04; 95% CI: 0.93, 1.16; p = 0.51). OS and DFS for delayed treatment were non-inferior compared to no delay, but might be due to better tumor biology/smaller tumor size in the delayed group.

• Industrial Engineering and Management Systems
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• v.13 no.1
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• pp.15-28
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• 2014

Evaluation of the implementation and performance of a firm's green supply chain management (GSCM) is an ongoing process. Balanced scorecard is a multi-criteria evaluation concept that highlights implementation and performance measures. The literature on the framework is abundant literature but scarce on how to build a hierarchical framework under uncertainty with dependence relations. Hence, this study proposes a hybrid approach, which includes applied interpretive structural modeling to build a hierarchical structure and uses the analytic network process to analyze the dependence relations. Additionally, this study applies the fuzzy set theory to determine linguistic preferences. Twenty dependence criteria are evaluated for a GSCM implemented firm in Taiwan. The result shows that the financial aspect and life cycle assessment are the most important performance and weighted criteria.

• ETRI Journal
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• v.28 no.4
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• pp.486-494
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• 2006

Two current-mode and/or voltage-mode quadrature oscillator circuits each using one fully-differential second-generation current conveyor (FDCCII), two grounded capacitors, and two (or three) grounded resistors are presented. In the proposed circuits, the current-mode quadrature signals have the advantage of high-output impedance. The oscillation conditions and oscillation frequencies are orthogonally (or independently) controllable. The current-mode and voltage-mode quadrature signals can be simultaneously obtained from the second proposed circuit. The use of only grounded capacitors and resistors makes the proposed circuits ideal for integrated circuit implementation. Simulation results are also included.

• Journal of the Korean Institute of Rural Architecture
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• v.8 no.1
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• pp.52-61
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• 2006

From the mid-nineteenth century, Korean have emigrated to Tumen riverside. Their communities have different characters in accordance with the time, intention, and birthplace of emigrants who inclined to keep their fradifin and culture. There are many causes about the formation of communities influenced by Dynasty's Policy in 1885, one of the reasons is to approve Han Min Zhuan Ken Di Qu(legal land development right for Korean immigrants), and provide land development district for Korean immigrants in the north region of Tumen river from 1885. In Tumen riverside, 69 Ferry and wade viuaces have existed for more than 90 years By and large, 21 communities and distributed in He-Long city, 28 communities in Long-Jing city, and 10 communities in tu-men city, and 10 communities in Hun-Chun city.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3889-3892
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• 2012

Aims: The purposes of this study were to (1) to identify the causes of cancer in breast cancer survivors in Taiwan; and (2) to investigate the influence of demographic characteristics and breast cancer-related factors on the cause of cancer. Materials and method: This study details the related investigative results on survivors with breast cancer using a descriptive and correlational design. A convenience sampling approach was employed. A structured questionnaire was used to assess the participants. Results: A total of 230 breast cancer survivors completed the questionnaire. Low-scoring cause of cancer participants were older adults (OR = 2.49, p<0.05) who were already of menopausal status (OR = 2.28, p < 0.05). Around 72% of particpants agreed high responsibility. Our breast cancer survivors felt stress had caused their breast cancer. Conclusion: These findings are helpful in understanding the relationship between cause of cancer and related factors in breast cancer survivors.