• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제16권1호
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• pp.53-60
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• 2013

In Crohn's disease, mild gastrointestinal bleeding often occurs; however massive gastrointestinal hemorrhage, which can have a dramatic effect on a patient's vital sign, is rare. This could result in potentially life-threatening complications, which can lead to death. Massive hemorrhagic Crohn's disease is not well known and for this reason, they are a diagnostic and therapeutic challenge. Various diagnostic and therapeutic methods are currently being developed and used. The surgical method is often used only as a last measure since this approach has the risk of serious complications that may endanger patients. However, if massive bleeding continues even after all therapeutic methods are used, the surgical method must be implemented. In this case, all therapeutic methods were found to be ineffective; therefore, surgery was used as a last option. Ultimately, the surgical method was found to be successfully used to treat life-threatening hemorrhagic Crohn's disease.

• Journal of Hospice and Palliative Care
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• 제18권2호
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• pp.148-155
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• 2015

목적: 본 연구의 목적은 소아암 등의 난치병 환자들의 소원성취 프로그램에 대한 만족도가 질병 적응에 미치는 영향에서 레질리언스와 질병 스트레스가 갖는 매개효과를 파악하는데 목적이 있다. 방법: 한국메이크어위시재단에서 2010년부터 2014년까지 5년간 소원을 이루었던 1,597명의 환아 중 문장해독과 기억유지가 가능한 666명의 10대 이상에 해당하는 환아들에게 2015년 1월 2일에 모바일 설문지를 발송하였다. 그 결과 357명이 응답을 하였으나 성실하게 응답한 292명의 자료를 분석하였다. 결과: 소아 난치병 환아들이 소원성취 프로그램에 대해서 갖는 만족도는 레질리언스에 긍정적인 영향을 미치는 것으로 나타났다. 레질리언스는 질병 스트레스에 부정적인 영향을 미치고 질병 적응에는 긍정적인 영향을 미쳤으며, 질병 스트레스는 질병 적응에 부정적인 영향을 미치는 것으로 나타났다. 결론: 본 연구결과를 볼 때 소아 난치병 환자를 위한 소원성취 프로그램에 대한 만족도는 레질리언스의 향상과 질병 스트레스의 감소를 통하여 궁극적으로 이들의 질병에 대한 적응력을 높이는 효과가 있다는 것을 알 수 있다. 따라서 소아 난치병 환자들의 욕구와 특성을 면밀히 분석하여 소원성취 프로그램을 실행하고 만족도를 높이면 이들이 질병에 대해서 보다 적극적으로 대처할 수 있는 동시에 현재의 삶을 긍정적으로 영위할 수 있는 동기를 제공할 수 있을 것이다.

• Clinical and Experimental Pediatrics
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• 제55권10호
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• pp.359-366
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• 2012

Although most enterovirus infections are not serious enough to be life threatening, several enteroviruses such as enterovirus 71 are responsible for severe, potentially life-threatening disease. The epidemic patterns of enteroviruses occur regularly during the year, but they may change due to environmental shifts induced by climate change due to global warming. Therefore, enterovirus epidemiological studies should be performed continuously as a basis for anti-viral studies. A great number of synthesized antiviral compounds that work against enteroviruses have been developed but only a few have demonstrated effectiveness in vivo. No proven effective antiviral agents are available for enterovirus disease therapy. The development of a new antiviral drug is a difficult task due to poor selective toxicity and cost. To overcome these limitations, one approach is to accelerate the availability of other existing antiviral drugs approved for antiviral effect against enteroviruses, and the other way is to screen traditional medicinal plants.

• Clinical and Experimental Pediatrics
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• 제59권9호
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• pp.347-354
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• 2016

An apparent life-threatening event (ALTE) is defined as the combination of clinical presentations such as apnea, marked change in skin and muscle tone, gagging, or choking. It is a frightening event, and it predominantly occurs during infancy at a mean age of 1-3 months. The causes of ALTE are categorized into problems that are: gastrointestinal (50%), neurological (30%), respiratory (20%), cardiovascular (5%), metabolic and endocrine (2%-5%), or others such as child abuse. Up to 50% of ALTEs are idiopathic, where the cause cannot be diagnosed. Infants with an ALTE are often asymptomatic at hospital and there is no standard workup protocol for ALTE. Therefore, a detailed initial history and physical examination are important to determine the extent of the medical evaluation and treatment. Regardless of the cause of an ALTE, all infants with an ALTE should require hospitalization and continuous cardiorespiratory monitoring and evaluation for at least 24 hours. The natural course of ALTEs has seemed benign, and the outcome is generally associated with the affected infants' underlying disease. In conclusion, systemic diagnostic evaluation and adequate treatment increases the survival and quality of life for most affected infants.

• Journal of Trauma and Injury
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• 제33권4호
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• pp.260-263
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• 2020

Necrotizing fasciitis is an infection of the subcutaneous tissue that results in destruction of the fascia and is disproportionately common in patients with chronic liver disease or diabetes. Necrotizing fasciitis of the head and neck is rare, but has a high fatality rate. A 50-year-old man with a past medical history of diabetes reported a chief complaint of a wound in the posterior neck due to trauma. The wound had grown and was accompanied by pus and redness, and the patient had a fever. When the patient was referred to department of plastic & reconstructive surgery, the sternocleidomastoid muscle, semispinalis capitis muscle, splenius capitis muscle, and trapezius muscles were exposed, and the size of the defect was about 25×20 cm. Dead tissue resection was performed before negative-pressure wound therapy, followed by a split-thickness skin graft (STSG). After a 2-week course of aseptic dressing post-STSG, the patient recovered completely. No postoperative complications were observed for 1 year. Necrotizing fasciitis is a life-threatening, rapidly spreading infection, requiring early diagnosis and active surgical treatment. In addition, broad-spectrum antibiotics are required due to the variety of types of causative bacteria. Broad necrotizing fasciitis of the posterior neck is rare, but can quickly progress into a life-threatening stage.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2011년도 춘계학술발표대회
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• pp.89-91
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• 2011

Diabetes is a chronic disease which may lead to other life threatening health complications like heart disease, stroke and peripheral vascular disease that diminished quality of life. In order to assists diabetic patients, we develop a smartphone application to monitor the regular medicine intake and exercise routines through repetitive user friendly and motivational reminders. Health-practitioners including doctors and nurses can frequently view and analyze the daily routine of patients through a web-interface. This paper presents architecture to improve the quality of life with android smart phone as user terminal, and integration of webbased application through web services for health care professionals. We also explain how each of the application interacts with each other and internal integration.

• Clinics in Shoulder and Elbow
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• 제10권1호
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• pp.136-139
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• 2007

견관절경 수술로 많은 질환을 치료할 수 있으며 개방 술식에 비하여 많은 장점을 가지고 있다. 드물게 견관절 수술 후 세척액이 관절외 연부조직으로 유출되어 목과 인두에 부종을 유발하는 기도합병증이 보고되고 있다. 이 논문은 관절경하 회전근 개 봉합 수술 후 치명적으로 발생했던 기도 폐쇄를 보고하고자 한다. 결론적으로 이러한 위험한 합병증을 예방하기 위해서는 마취된 환자의 경우 불편감을 호소할 수 없으므로 술자들의 경부 부종 상태를 주기적으로 점검하여야 할 것이다.

• The Plant Pathology Journal
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• 제33권2호
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• pp.103-108
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• 2017

World wheat production is now under threat due to the wheat blast outbreak in Bangladesh in early March 2016. This is a new disease in this area, indicating the higher possibility of this pathogen spreading throughout the Asia, the world's largest wheat producing area. Occurrence of this disease caused ~3.5% reduction of the total wheat fields in Bangladesh. Its economic effect on the Bangladesh wheat market was little because wheat contributes to 3% of total cereal consumption, among which ~70% have been imported from other countries. However, as a long-term perspective, much greater losses will occur once this disease spreads to other major wheat producing areas of Bangladesh, India, and Pakistan due to the existing favorable condition for the blast pathogen. The wheat blast pathogen belongs to the Magnaporthe oryzae species complex causing blast disease on multiple hosts in the Poaceae family. Phylogenetic analysis revealed that the Bangladesh outbreak strains and the Brazil outbreak strains were the same phylogenetic lineage, suggesting that they might be migrated from Brazil to Bangladesh during the seed import. To protect wheat production of Bangladesh and its neighbors, several measures including rigorous testing of seed health, use of chemicals, crop rotation, reinforcement of quarantine procedures, and increased field monitoring should be implemented. Development of blast resistant wheat varieties should be a long-term solution and combination of different methods with partial resistant lines may suppress this disease for some time.

• Journal of Chest Surgery
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• 제49권3호
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• pp.210-213
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• 2016

Congenital cystic adenomatoid malformation is a rare, but well-known disease. It can be managed conservatively in patients without symptoms or require surgical removal when symptomatic. The surgical option of choice is en bloc resection of the affected lesion. We report an experience of life-threatening congenital cystic adenoid malformation in a low-birth-weight (1,590 g) premature neonate who was successfully treated with a lobectomy of the lung.

• Annals of Clinical Neurophysiology
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• 제25권1호
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• pp.38-40
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• 2023

Acute pulmonary embolism (PE) is a life-threatening disease that manifests with cardiorespiratory symptoms. Syncope can be a rare, but warning sign of PE. We report a case of a 49-year-old male diagnosed with PE who presented with recurrent syncope prior to typical cardiorespiratory symptoms. His computed tomography pulmonary angiogram revealed bilateral PE. Syncope can be a rare clinical symptom of PE, but considering lethality of the disease, a differential diagnosis of PE should be considered in patients with recurrent syncope.