• International Journal of Computer Science & Network Security
• /
• 제22권3호
• /
• pp.276-284
• /
• 2022

The research aims to study the dynamics of academic procrastination and its impact on the mental health of students during the transition to distance learning during the COVID-19 pandemic. At the beginning of the COVID-19 pandemic, it was identified a declining tendency of overall rates of academic procrastination and at the same time increase in the number of carriers of mid and high levels of academic procrastination. The decline in the general rates of academic procrastination at the beginning of 2021 testifies to the adaptation processes experienced by students to the conditions of distance learning. It was documented that students' academic procrastination is accompanied by a steady negative emotional tension. During the transition to distance learning, the intensity of students' learning activity has increased, which altogether causes stress as one of the main reasons for the academic procrastination among future psychologists. The study identified a risk of academic procrastination manifestation among students for their mental health, which provides a basis for developing and testing a program to prevent the phenomenon of academic procrastination among degree-seeking students.

• 한국융합학회논문지
• /
• 제12권11호
• /
• pp.475-485
• /
• 2021

본 연구는 기혼직장여성의 우울에 영향을 미치는 요인을 파악하기 위하여 여성가족패널조사(2017년) 자료를 활용하여 2차 분석을 수행한 서술적 조사연구이다. 만 19세 이상 64세 이하의 기혼직장여성 총 3,820명을 대상으로 교차분석과 로지스틱 회귀분석을 실시하였다. 결혼생활 특성에서는 결혼생활에 대한 감정(p=.003), 남편에 대한 인식(p<.001), 가사노동 분담 만족도(p=.008), 자녀 수(p=.027), 건강 특성에서는 지각된 건강상태,(p<.001) 흡연 여부(p=.012), 직업 특성에서는 평균 월급(p=.008), 일 만족도(p=.006)가 기혼직장여성의 우울 영향요인으로 나타났다. 따라서 기혼직장여성의 우울관리와 예방을 위해서는 결혼생활과 관련된 업무를 배우자와 협의하여 동등하게 배분할 수 있는 가정 내에서의 노력뿐 아니라 개인의 지각된 건강상태를 증진시키기 위한 노력도 필요할 것이다. 또한 흡연이 스트레스 해소에 도움을 준다는 잘못된 인식에 대한 교육이 무엇보다 중요하다.

• 산업융합연구
• /
• 제19권6호
• /
• pp.155-164
• /
• 2021

본 연구는 다문화청소년의 개인·정서·부모·사회·환경적 요인이 진로미결정에 미치는 영향 요인을 파악하는 것을 목적으로 한다. 조사대상자는 현재 고등학교에 재학 중이며 아버지가 한국인인 다문화청소년 1,146명을 다문화청소년패널(MAPS) 7차 자료에서 추출해 다중회귀분석으로 검증했다. 연구결과는 첫째, 다문화청소년의 개인 요인인 자아존중감과 사회·환경적 요인인 학교생활적응 및 다문화 수용이 진로미결정에 긍정적인 영향을 미치는 것으로 나타났다. 둘째, 정서적 요인으로 우울증과 부모요인인 방임이 진로미결정에 부적인 영향을 미치는 것을 확인하였다. 하지만 부모-자녀 의사소통은 진로미결정에 영향을 미치지 않는 것으로 확인되었다. 이와같은 연구결과를 토대로 다문화청소년의 진로 미결정을 사전에 예방하고 진로미결정을 위한 기초자료를 제공했다는 점에서 의의가 있다.

• Journal of Ginseng Research
• /
• 제46권4호
• /
• pp.543-549
• /
• 2022

Background: In physical activity or labor, the human body is in a state of high intensity stress, and all parts or physiological functions of the body respond positively to maintain or balance the need for movement. The human body has many physiological changes in the process of movement, and fatigue is the external manifestation of various complex changes inside the human body. Fatigue is also a physiological mechanism of self-protection after the body reaches a certain level of activity, which can prevent the occurrence of life-threatening excessive functional failure. The generation of fatigue is a very complex process, and its mechanism has not been concluded yet. Therefore, it is an important work to search and screen the effective components of natural plants that have anti-fatigue effect and to explore their mechanism. Methods: This was a 8-week, randomized, double-blind, placebo-controlled clinical trial. A total of 110 subjects who passed physical examination were included according to the scheme design, and randomly divided into a test group which was given KRG and a placebo control group. The calculation is carried out according to the standard of sub-high-intensity exercise test. Results: There was no adverse effect on safety index of subjects after taking red ginseng capsule. After KRG treatment, subjective strength grade is significant lower than placebo treatment. Blood lactic acid content is significantly get lower after trial in KRG group, and significant lower than placebo group. Creatine phosphokinase(CK) content is significantly get lower after trial in KRG group, and significant lower than placebo group. Conclusion: According to the criterion in the test scheme, the result shows that KRG is helpful on relieving physical fatigue.

• 한국동물생명공학회지
• /
• 제37권3호
• /
• pp.183-192
• /
• 2022

Lipopolysaccharide (LPS) is an endotoxin factor present in the cell wall of Gram-negative bacteria and induces various immune responses to infection. Recent studies have reported that LPS induces cellular stress in various cells including oocytes and embryos. Melatonin (N-acetyl-5-methoxytryptamine) is a regulatory hormone of circadian rhythm and a powerful antioxidant. It has been known that melatonin has an effective function in scavenging oxygen free radicals and has been used as an antioxidant to reduce the cytotoxic effects induced by LPS. However, the effect of melatonin on LPS treated early embryonic development has not yet been confirmed. In this study, we cultured mouse embryos in medium supplemented with LPS or/and melatonin up to the blastocyst stage in vitro and then evaluated the developmental rate. As a result of the LPS-treatment, the rate of blastocyst development was significantly reduced compared to the control group in all the LPS groups. Next, in the melatonin only treated group, there was no statistical difference in embryonic development and no toxic effects were observed. And then we found that the treatment of melatonin improved the rates of compaction and blastocyst development of LPS-treated embryos. In addition, we showed that melatonin treatment decreased ROS levels compared to the LPS only treated group. In conclusion, we demonstrated the protective effect of melatonin on the embryonic developmental rate reduced by LPS. These results suggest a direction to improve reproduction loss that may occur due to LPS exposure and bacterial infection through the using of melatonin during in vitro culture.

• Journal of Microbiology and Biotechnology
• /
• 제32권9호
• /
• pp.1168-1177
• /
• 2022

Parkinson's disease (PD) is the second-most prevalent neurodegenerative disease and is characterized by dopaminergic neuronal death in the midbrain. Recently, the association between alterations in PD pathology and the gut microbiota has been explored. Microbiota-targeted interventions have been suggested as a novel therapeutic approach for PD. Agathobaculum butyriciproducens SR79^T (SR79) is an anaerobic bacterium. Previously, we showed that SR79 treatment induced cognitive improvement and reduced Alzheimer's disease pathologies in a mouse model. In this study, we hypothesized that SR79 treatment may have beneficial effects on PD pathology. To investigate the therapeutic effects of SR79 on PD, 6-hydroxydopamine (6-OHDA)-induced mouse models were used. D-Amphetamine sulfate (d-AMPH)-induced behavioral rotations and dopaminergic cell death were analyzed in unilateral 6-OHDA-lesioned mice. Treatment with SR79 significantly decreased ipsilateral rotations induced by d-AMPH. Moreover, SR79 treatment markedly activated the AKT/GSK3β signaling pathway in the striatum. In addition, SR79 treatment affected the Nrf2/ARE signaling pathway and its downstream target genes in the striatum of 6-OHDA-lesioned mice. Our findings suggest a protective role of SR79 in 6-OHDA-induced toxicity by regulating the AKT/Nrf2/ARE signaling pathway and astrocyte activation. Thus, SR79 may be a potential microbe-based intervention and therapeutic strategy for PD.

• 한국전문물리치료학회지
• /
• 제28권2호
• /
• pp.93-100
• /
• 2021

Background: Lateral epicondylitis (LE) is the most common chronic musculoskeletal conditions of the upper extremity with pain and wrist extension disability. The tendon which is most affected is the extensor carpi radialis brevis (ECRB). Previous study evaluated the effect of taping technique on patient with LE, but no study investigated the changes of electromyography (EMG) on ECRB when using dynamic taping (DT) technique. Objects: The aim of this study was to investigate the effect of DT technique using dynamic tape on muscle activity of ECRB during wrist isometric extension, isotonic extension and flexion. Methods: Twenty-one healthy subjects volunteered to participate in this study. Subjects were instructed to perform wrist isometric extension, isotonic extension and flexion without and with DT on origin area of ECRB. Wrist isometric extension was performed at 75%, 50% and 25% (%maximal voluntary contraction force), respectively, based on maximum contraction force. Isotonic extension and flexion test used dumbbell. EMG data was collected from ECRB. Results: EMG of ECRB were statistically significant decrease in wrist isotonic extension after DT (p < 0.05). Significant increase in wrist isometric extension during 25% and 50% force task (p < 0.05). Conclusion: This study applied DT technique to suppress the wrist extensor muscles in 21 healthy adults in their twenties. Change in muscle activity was compared in the ECRB muscle during wrist isometric extension, isotonic extension and flexion task. Based on the results of this study, the DT technique applied to the wrist and forearm area can reduce the load on the wrist extensors when the wrist performs various movements during daily life movements or repetitive tasks, and by using these effects, excessive stress is applied to tennis elbow patients.

• International Journal of Internet, Broadcasting and Communication
• /
• 제13권2호
• /
• pp.145-155
• /
• 2021

With the recent rapid improvement in the standards of life and westernization of dietary lifestyles, the consumption of high-calorie diets such as high-fat and high-protein red meat and instant foods has increased, while less vegetables containing dietary fiber are consumed. In addition to that, stress, erroneous dietary behaviors, and contaminated environments are linked to the risk of developing ulcerative colitis, which is on the rise. Another cause of ulcerative colitis is that involve laxative abuse, including repeated, frequent use of laxatives, and include such conditions as deteriorated bowel function, irritable bowel syndrome, diarrhea, intestinal inflammation, etc. The present study aimed to investigate the comparative evaluation of pharmacological efficacy between sulfasalazine alone and combination with herbal medicine on dextran sodium sulfate (DSS)-induced UC in mice. Balb/c mice received 5% DSS in drinking water for 7 days to induce colitis. Animals were divided into five groups (n = 9): group I-normal group, group II-DSS control group, group III-DSS + sulfasalazine (30 mg/kg), group IV-DSS + sulfasalazine (60 mg/kg), group V-DSS + sulfasalazine (30 mg/kg) + Radish Extract mixture (30 mg /kg) (SRE). DSS-treated mice developed symptoms similar to those of human UC, such as severe bloody diarrhea and weight loss. SRE supplementation, as well as sulfasalazine, suppressed colonic length and mucosal inflammatory infiltration. In addition, SRE treatment significantly reduced the expression of pro-inflammatory signaling molecules through suppression both mitogen-activated protein kinases (MAPK) and nuclear factor-kappa B (NF-κB) signaling pathways, and prevented the apoptosis of colon. Moreover, SRE administration significantly led to the up-regulation of antioxidant enzyme including SOD and Catalase. This is the first report that Radish extract mixture combined with sulfasalazine protects against experimental UC via the inhibition of both inflammation and apoptosis, very similar to the standard-of-care sulfasalazine.

• 한국융합학회논문지
• /
• 제13권5호
• /
• pp.365-372
• /
• 2022

한국은 고령화 사회에 접어들었으며, 노인의 일상생활에 직접적인 영향을 주는 근골격계는 근육운동과 유연성이 필수적이다. 특히 요가는 정신과 신체를 완화시키고 스트레스 대처 능력을 향상시킨다. 이에 요가와 관련된 키워드를 알아보기 위해 뉴스분석시스템인 빅카인즈(BIGKinds)에서 제공하는 신문기사를 활용하여 2019년 1월 1일부터 2021년 12월 31일까지의 기사를 수집하였으며, 월별 키워드 분석과 가중도에 따른 관계도 분석을 실시하였다. 결론적으로 첫째, 요가는 계절로 볼 때 봄과 가을에 관심이 높은 것으로 나타났다. 둘째, 최근 요가는 비대면 방식을 통해서 실시되고 있으며, 다양한 SNS를 활용하여 운영되고 있는 것으로 나타났다. 셋째, 요가를 지도하는 요가강사, 트레이너의 관련 기사가 높게 나타났으며, 이에 따라 온라인 지도의 중요성과 관심도를 알 수 있다. 향후 요가 관련 운동프로그램 개발과 국민 생활체육 발전을 위한 기초자료로 활용될 것을 기대한다.

• 대한본초학회지
• /
• 제34권3호
• /
• pp.1-7
• /
• 2019

Objectives : Amyloid ${\beta}(A{\beta})$ could induce cognitive deficits through oxidative stress, inflammation, and neuron death in Alzheimer's disease (AD). This study was investigated the effect of Angelica keiskei KOIDZUMI (AK) on memory in $A{\beta}$-induced an AD model. Methods : AK was extracted uses 70% ethanol solvent. Total polyphenol and flavonoids content were obtained by the Folin-Ciocalteu and the Ethylene glycol colorimetric methods, respectively. The antioxidant activities were assessed through free radical scavenging assays using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothiazolin-6-sulfonic acid) (ABTS) methods. Intracerebroventrical (i.c.v) injection of $A{\beta}$ 1-42 was used to induce AD in male ICR mice, followed by administrations of 5, 10 or 20 mg/kg AK on a daily. Animals were subjected to short and long term memory behavior in Y-maze and passive avoidance test. Results : The total polyphenol and flavonoids contents of the AK extract were $88.73{\pm}6.36mg$ gallic acid equivalent/g, $84.21{\pm}5.04mg$ rutin equivalent/g, respectively. The assays of DPPH and ABTS revealed that AK extract in treated concentrations (31.25, 62.5, 125, 250, 500, $1000{\mu}g/m{\ell}$) increased antioxidant activity in a dose-dependent manner. Oral administration of AK extract significantly reversed the $A{\beta}$ 1-42-induced decreasing of the spontaneous alternation in the Y-maze test and $A{\beta}$ 1-42-induced shorting of the step-through latency in the passive avoidance test. Conclusions : The findings suggest that AK indicated the antioxidant protective effects against $A{\beta}$-induced memory deficits, and therefore a potential lead natural therapeutic drug or agent for AD.