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비알코올성 지방간 질환에 대한 침치료의 효과 : 체계적 고찰 (Clinical Effectiveness of Acupuncture in the Treatment of Non-Alcoholic Fatty Liver Disease: A Systematic Review)

  • 현준;이주복;김소연;한창우
    • 대한한방내과학회지
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    • 제39권6호
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    • pp.1206-1224
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    • 2018
  • Purpose: This systematic review was planned and performed in order to determine the clinical effectiveness of acupuncture for non-alcoholic fatty liver disease (NAFLD). Methods: We searched related randomized controlled trials in several medical online databases, including China National Knowledge Infrastructure (CNKI), Excerpta Medica dataBASE (EMBASE), Public/Publisher MEDLINE (PubMed), Cochrane Central Register of Controlled Trials (CENTRAL), National Digital Science Library (NDSL), and Research Information Sharing Service (RISS). NAFLD related outcomes were extracted from the included trials and meta-analyzed. Results: From the 8 included trials, the values of the following examinations were extracted: liver ultrasonography, liver CT, body fat CT, aspartate transaminase (AST), alanine transaminase (ALT), gamma-glutamyltransferase (GGT), total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) cholesterol, high density lipoprotein (HDL) cholesterol, fasting blood sugar (FBS), hosmeostatic model assessment for insulin resistance (HOMA-IR), weight, body mass index (BMI), waist hip ratio (WHR), obesity degree, body fat mass, body fat rate, leptin, malondialdehyde (MDA), and super oxide dismutase (SOD). In the 4 outcomes, cure rate in liver ultrasonography (RR=1.56; 95%CI=1.05~2.31; P=0.03), cure rate in liver CT (RR=2.23; 95%CI=1.33~3.72; P=0.002), TC (MD=-0.78; 95%CI=-1.41~-0.15; P=0.02), and TG (MD=-2.05; 95%CI=-3.88~-0.21; P=0.03), acupuncture was more effective than the control intervention. Conclusions: In this meta-analysis, acupuncture relieved hepatic steatosis, and reduced TC, and TG in NAFLD patients. more well-planned studies are still needed due to the heterogeneity and the considerable methodological flaws in the analyzed trials.

요추 척추관 협착증에 대한 전침 치료의 효과: 체계적 문헌고찰 및 메타분석 (Electroacupuncture for Lumbar Spinal Stenosis: A Systematic Review and Meta-Analysis)

  • 나복연;손우석;김영준;우창훈
    • 한방재활의학과학회지
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    • 제33권3호
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    • pp.67-78
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    • 2023
  • Objectives To evaluate the evidence supporting the efficacy and safety of electroacupuncture for lumbar spinal stenosis. Methods We searched eight electronic databases (PubMed, EMBASE, Cochrane Library, Chinese Academic Journals, Research Information Sharing Service, ScienceOn, KMBASE, DBpia) and related two journals up to March 2023. We included randomized controlled trials of testing electroacupuncture for lumbar spinal stenosis patients. The methodological quality of relevant randomized controlled trials assessed by the Cochrane risk of bias tool. Results Among 90 articles that were searched, seven randomized controlled trials involving 474 participants were finally selected in this systematic review. Electroacupuncture was more effective on lumbar spinal stenosis compared with other treatments including analgesics, acupuncture, bed rest and exercise therapy, but showed ambiguous effect compared with physical therapy. Most of the side effects and adverse reactions were reported as minor and temporary. Conclusions Electroacupuncture for lumbar spinal stenosis was more effective than analgesics, acupuncture, bed rest and exercise therapy. In terms of safety, it was limited because there are many papers that do not mention side effects and adverse reactions related to electroacupuncture. Additional studies are needed to determine the effect of electroacupuncture on lumbar spinal stenosis.

국내 운동 관련 메타분석 논문의 질 평가 (Review of Meta-analysis Research on Exercise in South Korea)

  • 송영신;강문희;김선애;신인수
    • 대한간호학회지
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    • 제44권5호
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    • pp.459-470
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    • 2014
  • Purpose: The purpose of this study was to evaluate the quality of meta-analysis regarding exercise using Assessment of Multiple Systematic Reviews (AMSTAR) as well as to compare effect size according to outcomes. Methods: Electronic databases including the Korean Studies Information Service System (KISS), the National Assembly Library and the DBpia, HAKJISAand RISS4U for the dates 1990 to January 2014 were searched for 'meta-analysis' and 'exercise' in the fields of medical, nursing, physical therapy and physical exercise in Korea. AMSTAR was scored for quality assessment of the 33 articles included in the study. Data were analyzed using descriptive statistics, t-test, ANOVA and ${\chi}^2$-test. Results: The mean score for AMSTAR evaluations was 4.18 (SD=1.78) and about 67% were classified at the low-quality level and 30% at the moderate-quality level. The scores of quality were statistically different by field of research, number of participants, number of databases, financial support and approval by IRB. The effect size that presented in individual studies were different by type of exercise in the applied intervention. Conclusion: This critical appraisal of meta-analysis published in various field that focused on exercise indicates that a guideline such as the PRISMA checklist should be strongly recommended for optimum reporting of meta-analysis across research fields.

부정맥의 뜸 치료 효과에 대한 체계적 문헌고찰 (The Effect of Moxibustion Treatment for Cardiac Arrhythmia : A Systematic Review)

  • 이보라;황주영;권정남
    • 대한한의학회지
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    • 제40권3호
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    • pp.99-111
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    • 2019
  • Objectives: The purpose of this study was to assess the effects of moxibustion treatment for Cardiac arrhythmia through a systematic review. Methods: Electronic database including Cochrane library, Pubmed, China National Knowledge Infrastructure, Embase, DBpia, and Korean studies Information Service System were searched by combining the keywords such as "arrhythmias", "cardiac arrhythmias", "心律失常", "moxibustion" and "艾灸". Through the searching, 5 randomized controlled trials(RCTs) were included except animal testing and cellular experiment etc. The quality of each RCTs was assessed using the Cochrane risk of bias tool. Results: We included 5RCTs involving 468 participants. Two RCTs compared moxibustion versus conventional treatment, another RCT compared moxibustion plus acupuncture versus conventional treatment, another RCT compared moxibustion plus herbal medicine verus conventional treatment, the other RCT compared moxibustion plus herbal medicine and ointment versus conventional treatment. These studies were evaluated by the efficacy rate of treatments. Studies measured outcomes in efficacy, heart rate, electrocardiogram and symptoms. Each of 5 trials statistically showed a significant differences in efficacy rate. One study reported about side effects and another study reported about complications. The overall risk of bias was unclear in 5 studies. Conclusions: The evidence suggests that moxibustion treatment may help to reduce cardiac arrhythmia, however, it is limited, low-certainty and we cannot rule out benefits or risks with this treatment. High-quality studies that report adverse effects are needed.

만성 골반염의 한약 치료에 대한 무작위 대조 임상시험 연구 분석 (Review of Randomized Controlled Trials of Traditional Herbal Medicine for Chronic Pelvic Inflammatory Disease)

  • 노언지;안수연;김동철
    • 대한한방부인과학회지
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    • 제34권4호
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    • pp.46-61
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    • 2021
  • Objectives: The purpose of this review is to overview the studies of traditional herbal medicine for chronic pelvic inflammatory disease. Methods: We searched relevant studies using seven databases (The Journal of Korean obstetrics & gynecology, National Digital Science Library (NDSL), Research Information Sharing Service (RISS), Oriental Medicine Advanced Searching Integrated System (OASIS), Pubmed, Cochrane, Chinese National Knowledge Infrastructure (CNKI)). Data retrieval was carried out on April 5, 2021 and the papers published from January 1, 2015 to March 31, 2021 were included. The risk of bias was assessed by using Cochrane's risk of bias tool. Results: 524 studies were searched in domestic and foreign databases, and 7 studies were finally selected. In all studies, the treatment group was treated with oral traditional herbal medicine and the control group was treated with western medicine. Although the evaluation index was slightly different for each study, all studies used total efficacy rate index. In all 7 studies, the treatment group was more effective than the control group. Conclusions: Traditional herbal medicine can be an effective option in treating chronic pelvic inflammatory disease. Further high quality studies which include large number should be carried out to confirm the evidence and safety of traditional herbal medicine treatment.

자궁근종을 동반한 난임 여성의 한의학적 치료에 대한 연구 동향 (A Review on Research of Korean Medicine Treatments for Infertile Women with Uterine Myoma)

  • 고은빈;박남경;최민영;이진무;이창훈;장준복;황덕상
    • 대한한방부인과학회지
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    • 제36권3호
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    • pp.196-210
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    • 2023
  • Objectives: The purpose of this study is to review the research trends of infertile women with uterine myoma in Korean medicine and to recognize the efficacy of Korean medicine intervention. Methods: A search was conducted on November 18, 2022, using six databases, including Research Information Sharing Service (RISS), Oriental Medicine Advanced Searching Integrated System (OASIS), Cochrane Library Central, Pubmed, China National Knowledge Infrastructure (CNKI) and WangFang Med Online. We analyzed the studies using Korean medicine on women with uterine myoma preparing for pregnancy or complaining infertility. Results: Total 4 studies were selected and all of which were case reports. Among 6 cases, Korean medicine treatment including herbal medicine, acupuncture, electroacupuncture, moxibustion was used alone. Ikgibohyeol-tang-gami-bang, Gyejibokryeong-hwan, Saenghwa-tang-gami-bang were prescribed in 2 cases each. Angelicae Gigantis Radix and CV4 were most frequently used herb and acupoint. All subjects were successful in becoming pregnant. Conclusion: This review shows that Korean medicine treatment can be effective in infertile women with uterine myoma. However, the number of included studies is small, so the level of evidence needs to be raised through more clinical studies in the future.

광주크박스 저장장치에 기반한 비디오 서버 (Video Server with Optical Mass Storage)

  • 이종민;차호정;오재학;박병준
    • 한국정보과학회논문지:시스템및이론
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    • 제29권6호
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    • pp.318-330
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    • 2002
  • 본 논문은 광주 크박스와 테잎 라이브러리 같은 Tertiary 저장 장치를 미디어 저장 장치로 사용하는 비디오 서버의 설계와 구현에 대하여 기술한다. Tertiary 저장 장치를 스트리밍 서버의 미디어 저장 장치로 사용하기 위해서는 Tertiary 저장 장치의 하드웨어적인 특성을 고려한 적절한 스트리밍 서비스 모델이 필요하다. 논문에서는 연속 미디어의 특성을 고려한 스트림 스케쥴링, 디스크 캐슁, 사용자 수용 제어 정책 등을 제안하고 이를 핵심으로 하는 스트리밍 서비스 모델을 제시한다. 제안된 시스템은 광주크박스 저장장치를 장착한 Windows 2000 플랫폼에서 구현되었고, 다양한 실험 및 성능 분석을 통해 제안된 정책들이 올바로 동작함을 검증하였다.

유사과제파악을 위한 검색 알고리즘의 개발에 관한 연구 (A Study on the Development of Search Algorithm for Identifying the Similar and Redundant Research)

  • 박동진;최기석;이명선;이상태
    • 한국콘텐츠학회논문지
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    • 제9권11호
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    • pp.54-62
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    • 2009
  • 국가적으로 그리고 각 연구기관에서는 투자의 효율성을 기하기 위하여 연구사업 선정과정에서 데이터베이스로부터 중복과제 혹은 유사과제를 검색하는 과정을 거친다. 최근 부얼리언 기반의 키워드 매칭 검색알고리즘의 발전 및 이를 채택한 검색엔진의 개발로 인하여 검색의 정확도가 많이 향상되었지만, 사용자가 입력하는 제한된 수의 키워드들에 의한 검색은 유사과제 파악과 우선순위의 결정에 어려움이 있다. 본 연구에서는 제안된 과제의 문서를 분석하여 다수의 색인어들을 추출하고, 이들에게 가중치를 부여한 후, 기존의 문서들과 비교하여 유사과제를 찾아내는 문서단위의 검색 알고리즘을 제안한다. 구체적으로 벡터공간검색(Vector-Space Retrieval)모델의 한 종류인 TFIDF(Term Frequency Inverse document Frequency)를 기본 구조로 채택한다. 또한 개발되는 알고리즘에는 연구과제 제안문서의 구조에 적합한 속성별 가중치(feature weighting)를 반영하고 검색속도의 향상을 위하여 K-최근접 문서(KNN: K-Nearest Neighbors) 기법도 반영한 알고리즘을 제시한다. 실험을 위하여 실제 연구제안 문서와 구조가 동일한 기존의 보고서를 사용하였는데, KISTI에서 운영하는 과학기술정보포털서비스인 NDSL에서 이미 분류해 놓은 4분야의 1,000 개 연구 보고서 문서를 발췌하여 실험을 하였다.

한국수출중소기업의 학습역량과 역동적 역량이 해외시장 경쟁우위에 미치는 영향에 관한 실증연구 (An Empirical Study on the Effects of Learning Competences and Dynamic Capabilities of Korean Small-sized Enterprises for Export-oriented to the Competitive Advantages)

  • 허영호;조연성
    • 국제지역연구
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    • 제14권3호
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    • pp.388-419
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    • 2010
  • 본 연구는 국내 수출중소기업의 해외시장 경쟁우위에 관한 연구모형과 가설을 제시하고 이를 통해 기대해 볼 수 있는 시사점을 살펴보는 것을 목적으로 하였다. 이를 위해 자원기반관점에서 살펴본 조직의 문화적 무형 자산으로서 조직학습역량과 역동적 역량이 해외시장 경쟁우위에 미치는 영향에 관한 통합적 모형을 구축하였다. 또한 기존의 역동적 역량에서 설명된 내부자원의 통합 재배치 역량을 각각 구분하여 사용하였다. 해외시장 경쟁우위에 있어서도 이를 각각 비용, 제품, 서비스 우위의 세 가지로 구분하여 선행요인과의 관계를 살펴보는 연구모형을 제안하였다. 총 386개의 표본을 대상으로 하여 구조방정식 모형을 이용하여 분석을 실시하였다. 분석 결과 학습역량은 역동적 역량 모두에 긍정적인 영향을 주고 있음을 확인하였다. 또한 학습역량은 경쟁우위 중에서 제품우위를 제외한 서비스와 비용 우위에 긍정적 영향을 주고 있다. 역동적 역량의 경우 자원 통합은 경쟁우위 전체 요소에 대해서 그리고 자원 재배치의 경우 제품과, 서비스 우위에 유의한 영향을 미치고 있음을 알 수 있었다. 또한 역동적 역량의 학습역량과 경쟁우위에 대한 매개효과 분석 결과 역동적 역량은 학습역량과 비용우위 사이를 매개하고 있음을 확인하였다.

좌골신경통에 대한 전침 치료: 체계적 문헌고찰 및 메타분석 (The Effect of Electro Acupuncture for Sciatica: A Systematic Review and Meta-analysis)

  • 김예은;안정훈;차윤엽;한인식;허인;박인화
    • 한방재활의학과학회지
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    • 제32권2호
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    • pp.105-121
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    • 2022
  • Objectives This study was conducted to evaluate the effect of electro-acupuncture for sciatica. Methods We searched 13 online databases (Kmbase, Research Information Sharing Service [RISS], National Digital Science Library [NDSL], Oriental Medicine Advanced Searching Integrated System [OASIS], Koreanstudies, Koreantk, DBpia, PubMed, Cochrane, EMBASE, Medline, China National Knowledge Infrastructure [CNKI], J-stage) to find randomized-controlled clinical trials (RCTs) that used electro-acupuncture for sciatica. Efficacy rate and visual analogue scale (VAS) were mainly analyzed as a main evaluation criteria. Results Among 583 articles that were searched, 24 RCTs were finally selected and 18 RCTs were statistically analyzed. Electro-acupuncture was more effective than acupuncture in terms of efficacy rate (p<0.00001) and VAS (p<0.00001). Also, Electro-acupuncture was more effective than western medication in terms of efficacy rate (p=0.0005). However, the effectiveness of electro-acupuncture was not identified compared to physical therapy (p=0.42). Electro-acupuncture significantly improved efficacy rate when combined with physical therapy than physical therapy alone (p<0.0001). In addition, electro-acupuncture plus Chuna manual therapy compared to Chuna manual therapy alone showed positive results for efficacy rate (p=0.05) and VAS (p<0.0001). Conclusions Based on results, the effectiveness of electro-acupuncture for sciatica was identified. However, this study has limitations because the RCTs included in this study were small in number and published in a particular region. Although this study could be a groundwork for well designed research for sciatica.