• 제목/요약/키워드: Library Value

검색결과 534건 처리시간 0.022초

이용자중심의 인터넷 컨텐츠 서비스에 관한 연구 (A Study on the user centered internet contents service)

  • 남태우;김성희
    • 정보관리학회지
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    • 제20권2호
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    • pp.263-283
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    • 2003
  • 본 연구에서는 이용자를 고객의 개념으로 이해하고 고객가치와 고객만족간의 관련성에 기초한 고객중심의 인터넷 컨텐츠 서비스에 관해 조사하였다. 그 결과 효율적인 인터넷 컨텐츠 서비스를 위한 고객가치 창출 핵심요인인 품질, 서비스, 비용은 컨텐츠 사이트 재방문 및 구매의도에 중요한 영향을 미치는 것으로 나타났다. 특히, 컨텐츠 서비스면에서 불만대응시간 및 고객지원체제에 대한 만족도 조사결과 다른 품질이나 비용에 비해 만족도가 낮은 것으로 나타나 이에 대한 개선이 필요한 것으로 나타났다. 따라서 학술정보기관에서도 이용자 서비스 연구를 고객가치수준에서 연구해야 할 것으로 보인다.

건축공간에서의 Vertical Garden의 활용에 관한 연구 - 건축물 외벽면 디자인 활용방법 - (The Research for Making Flexible Use of Vertical Garden in Architectural Space - The activated use design for architectural outside walls' space -)

  • 류효매;김은정;홍관선
    • 한국실내디자인학회논문집
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    • 제23권4호
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    • pp.12-22
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    • 2014
  • In this study, the basic information and study design characteristics of the Building Outer Wall Vertical Greening were analyzed. Recorded according to the type of research and analysis, through numerical statistics. Building Outer Wall Vertical Greening design the most appropriate and effective ways to present and try to guidelines. The scope of the research of Building Outer Wall Vertical Greening(2001-2013) was selected the most representative examples. Theory and statistical data analysis and case study research was conducted. The main academic monographs, Library Literature, specializing in design magazines and excerpts from the 28 cases analyzed specifically. Building Outer Wall Vertical Greening should be designed synthetically geographical features of the project, existing material, to consider the value of the building. Architect must be designed depending on accident and comprehensive expertise for architectural design of Building Outer Wall Vertical Greening. Building Outer Wall Vertical Greening requires the professional and comprehensive design approach depending on support of the government and people. However, purpose of use, plant, color, Formative expression, culture, locality, maintenance is properly applied in the design process is not easy.

Solution State Structure of pB1, the Mimotopic Peptide of Apolipoprotein B-100, by NMR

  • Lee, Sung-Ran;Kim, Dae-Sung;Kim, Hyo-Joon;Lee, Yong-Woo;Won, Ho-Shik
    • Bulletin of the Korean Chemical Society
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    • 제25권12호
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    • pp.1845-1849
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    • 2004
  • Apolipoprotein B-100 (Apo-B100) is a major protein component for low density lipoproteins (LDL). A number of mimetic peptides of Apo-B100 were screened from the phase-displayed random peptide library by utilizing monoclonal antibody (B9). Mimetic peptide for B9 epitope against apo B-100 was CRNVPPIFNDVYWIAF (pB1). From the BLAST search, the mimetic peptide pB1 had 40% homology with apo B-100. As a result of the structural determination of this mimotope using homo/hetero nuclear 2D-NMR techniques and NMR-based distance geometry (DG)/molecular dynamic (MD) computations, DG structure had low penalty value of 0.3-0.6 ${\AA}^2$ and the total RMSD was 0.5-1.5 ${\AA}. Moreover, pB1 structure included a weak $3_{10}$-helix from $Ile^7$,/TEX> to $Trp^{13}$.

Screening and Characterization of a Novel RNA Aptamer That Specifically Binds to Human Prostatic Acid Phosphatase and Human Prostate Cancer Cells

  • Kong, Hoon Young;Byun, Jonghoe
    • Molecules and Cells
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    • 제38권2호
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    • pp.171-179
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    • 2015
  • Prostatic acid phosphatase (PAP) expression increases proportionally with prostate cancer progression, making it useful in prognosticating intermediate to high-risk prostate cancers. A novel ligand that can specifically bind to PAP would be very helpful for guiding prostate cancer therapy. RNA aptamers bind to target molecules with high specificity and have key advantages such as low immunogenicity and easy synthesis. Here, human PAP-specific aptamers were screened from a 2'-fluoropyrimidine (FY)-modified RNA library by SELEX. The candidate aptamer families were identified within six rounds followed by analysis of their sequences and PAP-specific binding. A gel shift assay was used to identify PAP binding aptamers and the 6N aptamer specifically bound to PAP with a Kd value of 118 nM. RT-PCR and fluorescence labeling analyses revealed that the 6N aptamer bound to PAP-positive mammalian cells, such as PC-3 and LNCaP. IMR-90 negative control cells did not bind the 6N aptamer. Systematic minimization analyses revealed that 50 nucleotide sequences and their two hairpin structures in the 6N 2'-FY RNA aptamer were equally important for PAP binding. Renewed interest in PAP combined with the versatility of RNA aptamers, including conjugation of anti-cancer drugs and nano-imaging probes, could open up a new route for early theragnosis of prostate cancer.

대학도서관에서 업무지능과 대시보드의 활용방안에 관한 연구 (A Study on the Utilization of Business Intelligence and Dashboard in Academic Libraries)

  • 구중억
    • 정보관리학회지
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    • 제28권1호
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    • pp.263-283
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    • 2011
  • 업무지능(Business Intelligence)은 이해관계자들이 경영 의사결정을 내리는데 활용되고 있다. 대시 보드(Dashboard)는 데이터, 정보 또는 지식을 한 눈에 이해할 수 있도록 가시화해 줌으로써 업무지능을 지원해 주고 있다. 본 연구에서는 미국 ARL 소속 대학도서관의 웹사이트에서 도서관의 성과와 가치에 관한 정보공개 현황을 살펴보았다. 그리고 국외 대학도서관의 웹사이트에서 업무지능과 대시보드의 적용 사례를 분석하였다. 이를 통해 국내 대학도서관의 웹사이트에서 업무지능과 대시보드 정보시스템의 구축 및 활용을 제안하였다. 본 연구의 결과는 국내 대학도서관이 웹사이트를 통해 이해관계자들에게 도서관의 성과와 가치를 효율적으로 전달하고 의사소통의 도구로서 업무지능과 대시보드를 활용하기 위한 기초자료가 될 수 있을 것이다.

영상 분석을 이용한 수삼의 중량추정 (Estimating the Weight of Ginseng Using an Image Analysis)

  • 정석훈;고국원;이지연;이진호;서현석;이상준
    • 정보처리학회논문지:소프트웨어 및 데이터공학
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    • 제5권7호
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    • pp.333-338
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    • 2016
  • 본 연구의 목적은 수삼 등급을 판정하는 기준 중에서 수삼의 중량을 직접 측정하지 않고 영상 분석으로 가능한 근접하게 추정하는 것이다. 이를 위해 수삼영상 취득장치를 제작하였으며 126개의 수삼샘플을 대상으로 영상을 취득하였다. 각각의 수삼샘플의 중량을 측정하고 영상분석 데이터를 이용하여 중량추정공식을 산출하는데 이용하였다. 영상분석과 파라미터 추출과정에는 C언어 기반의 Labwindows/CVI 개발 툴과 오픈소스 라이브러리 OpenCV를 이용하였다. 영상분석 과정에서 추출한 파라미터와 중량과의 상관관계를 가장 잘 표현할 수 있는 필터설정 값을 추적하여 적용하였고, 최소제곱법을 사용한 선형 회귀분석으로 선형성을 가지는 0.9162의 강한 양의 상관계수 값을 얻을 수 있었다.

Gamma Radiation Induced Mutagenesis of Lysobacter enzymogenes for Enhanced Chitinolytic Activity

  • Lee, Young-Keun;Kim, Kyoung Youl;Senthilkumar, M.
    • 방사선산업학회지
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    • 제4권1호
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    • pp.65-71
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    • 2010
  • Two chitinase producing strains CHI2 and CHI4 were isolated from soybean rhizosphere soil. Both the strains belonged to Lysobacter enzymogenes as indicated by 16S rDNA sequence analysis. Though strain CHI2 and CHI4 produced extracellular chitinase, they differ in their chitinolytic activity. CHI4 produced approximately three times the higher amounts of enzyme than that of CHI2 under specified conditions. CHI2 produced $535.67U\;l^{-1}$ of chitinase after 48 h incubation with a specific activity of $3.91U\;mg^{-1}$ of protein while strain CHI4 produced $1584.13U\;l^{-1}$ of chitinase with a specific activity of $10.88U\;mg^{-1}$ protein. SDS-PAGE analysis indicated that the molecular weight of chitinase enzyme was approximately 45 kDa. A faint band with a molecular weight of 55 kDa reveals the possibility for the presence of another kind of chitin binding protein. Mutant library was developed by exposing the isolates to gamma rays at their $LD_{99}$ value (0.23 kGy). Totally, 11 mutants of CHI2 and CHI4 are reported to have enhanced chitinase activity. Several leaky mutant clones with decreased enzyme activity and a defective mutant (CHI2-M16) with complete loss of chitinase activity were also identified. CHI4-M18, CHI4-M8 and CHI4-M29 showed 78.8, 41.5, and 31.9% increased chitinase activity over wild type CHI4.

CHP Capacity Optimizer를 이용한 건물 열병합 시스템의 경제성 평가 (Economic Analysis of CHP System for Building by CHP Capacity Optimizer)

  • 윤린
    • 설비공학논문집
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    • 제20권5호
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    • pp.321-326
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    • 2008
  • This paper presents and analyzes the effects of on-grid electricity cost, fuel price and initial capital cost of a CHP system, on the optimum DG and AC capacity and NPV, by using the ORNL CHP Capacity Optimizer, which was applied to a library in a university. By considering the current domestic energy cost and initial capital cost, it is shown that the installation and operation of the CHP system is not economical. However, with the current domestic CHP installation cost and fuel price, the NPV achieved by the installation of CHP system is greater when the on-grid electricity price is a factor of ${\times}1.5$ the present value. Regarding the initial capital cost of the CHP system, the reduction of the DG cost is much more economical than that of the AC cost, with respect to NPV. Electricity cost and fuel price have opposite effects on NPV, and NPV is more sensitive to an increase of the electricity cost than an increase of the fuel price.

Open Posterior Approach versus Arthroscopic Suture Fixation for Displaced Posterior Cruciate Ligament Avulsion Fractures: Systematic Review

  • Song, Jae-Gwang;Nha, Kyung-Wook;Lee, Se-Won
    • Knee surgery & related research
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    • 제30권4호
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    • pp.275-283
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    • 2018
  • Purpose: To compare the clinical outcomes between the open posterior approach and arthroscopic suture fixation for displaced posterior cruciate ligament (PCL) avulsion fractures. Methods: A literature search was performed on MEDLINE, EMBASE, and the Cochrane Library databases. The inclusion criteria were as follows: papers written in English on displaced PCL avulsion fractures, clinical trial(s) with clear description of surgical technique, adult subjects, a follow-up longer than 12 months and modified Coleman methodology score (CMS) more than 60 points. Results: Twelve studies were included with a mean CMS value of 72.4 (standard deviation, 7.6). Overall, 134 patients underwent the open posterior approach with a minimum 12-month follow-up, and 174 patients underwent arthroscopic suture fixation. At final follow-up, the range of Lysholm score was 85-100 for the open approach and 80-100 for the arthroscopic approach. Patients who were rated as normal or nearly normal in the International Knee Documentation Committee subjective knee assessment were 92%-100% for the open approach and 90%-100% for the arthroscopic approach. The range of side-to-side difference was 0-5 mm for both approaches. Conclusions: Both arthroscopic and open methods for the treatment of PCL tibial-side avulsion injuries resulted in comparably good clinical outcomes, radiological healing, and stable knees.

곤충의 시각 신경망 기반 충돌감지 기술의 효율적인 VLSI 구조 설계 (Design of an Efficient VLSI Architecture for Collision Detection Based on Insect's Visual Interneuron)

  • 정수용;이재현;송덕용;박태근
    • 전기학회논문지
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    • 제67권12호
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    • pp.1671-1677
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    • 2018
  • In this research, the collision detection system based on insect's visual interneuron has been designed. The lobula giant movement detector (LGMD) corresponds to the movement value that increases in direct collision process. If the collision is detected by the LGMD only, it could generate a crash warning even in a non-collision situation, resulting in a lot of false alarms. Directionally sensitive movement detectors (DSMD) are directionally sensitive algorithm based on the elementary movement detectors (EMD) in four directions (up, down, left, and right). In this paper, we propose an efficient VLSI architecture for a realtime collision detection system that is robust to the surrounding environment while improving accuracy. The proposed architecture is synthesized with Dongbu Hightech 110nm standard cell library and shows 333MHz of maximum operating frequency and requires 8400 gates with about 16.5KB of internal memories.