• Proceedings of the Korean Society for Bioinformatics Conference
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• 2004.11a
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• pp.191-202
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• 2004

한국화합물은행(KCB)에서 보유중인 12만 개의 화합물을 주요 골격에 따라 분류하고, 4 가지 protease 작용점에 대한 활성도와 골격사이의 관계를 조사하였다. 화합물들은 합성기관의 합성 목적과 주요 고리골격 등을 고려하여 분류되었으며, 이를 이용하여 scaffold 분류를 위한 분류 계통도를 작성하였다. 화합물들은 이 계통도에 따라 7 가지의 race, 168 tribe, 493 parent, 439 child, 325 grandchild 등 1,087개의 scaffold로 분류되었으며, 각 race 및 scaffold 별 골격의 개수는 고르게 분포되었다. 골격별 분류 시스템을 이용하여 4 가지의 protease에 대한 활성도와 골격 간의 상관관계를 조사한 결과, Protease C에 대하여 몇 가지 골격이 활성이 뛰어남을 보였다.

• Journal of Society of Preventive Korean Medicine
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• v.22 no.2
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• pp.55-63
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• 2018

Objectives : This study was conducted to survey on the research trends of Pharmacopuncture in Korea. Methods : We searched Korean research database by using keyword 'Pharmacopuncture', 'Bee venom'. Korean research databases were Korean Studies Information Service System(KISS), Research Information Service System(RISS), National Digital Science Library(NDSL) and Korean Medicine Information System(OASIS). We classified articles identified by publish year, type of research and diseases. Results : We analyzed 533 studies. Clinical studies and non-clinical studies except literature studies were decreased from 2015. However, Literature studies had not shown particular change over the past decade. Pharmacopuncture treated disease was classified by Korean standard classification of disease(KCD), M-code (37.8%), G-code(18.4%) were frequently used. Conclusions : A variety of disease was treated by pharmacopuncture. It is necessary to increase the level of evidence of pharmacopuncture. through additional studies in the future.

• The korean journal of orthodontics
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• v.52 no.2
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• pp.112-122
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• 2022

Objective: This study aimed to present and evaluate a new deep learning model for determining cervical vertebral maturation (CVM) degree and growth spurts by analyzing lateral cephalometric radiographs. Methods: The study sample included 890 cephalograms. The images were classified into six cervical stages independently by two orthodontists. The images were also categorized into three degrees on the basis of the growth spurt: pre-pubertal, growth spurt, and post-pubertal. Subsequently, the samples were fed to a transfer learning model implemented using the Python programming language and PyTorch library. In the last step, the test set of cephalograms was randomly coded and provided to two new orthodontists in order to compare their diagnosis to the artificial intelligence (AI) model's performance using weighted kappa and Cohen's kappa statistical analyses. Results: The model's validation and test accuracy for the six-class CVM diagnosis were 62.63% and 61.62%, respectively. Moreover, the model's validation and test accuracy for the three-class classification were 75.76% and 82.83%, respectively. Furthermore, substantial agreements were observed between the two orthodontists as well as one of them and the AI model. Conclusions: The newly developed AI model had reasonable accuracy in detecting the CVM stage and high reliability in detecting the pubertal stage. However, its accuracy was still less than that of human observers. With further improvements in data quality, this model should be able to provide practical assistance to practicing dentists in the future.

• Journal of the Korean Society for Library and Information Science
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• v.52 no.3
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• pp.193-214
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• 2018

This study aims to analyze enactment of China's old and rare books management. For the purpose, the review on China's legal system and management related to old and rare books were studied. And this study investigated 4 laws, 6 administrative regulations, 4 sector regulations, and 13 administrative normativity papers. Among those, 5 major sources for old and rare books management were identified as follows : 1) China's National Civilization Protection Law in 2013, 2) China's Old and Rare Book Organization Directive in 1989, 3) Regulation on Management of Research, Organization, and Publication of Old and Rare Books in 1986, 4) Standards on Grading Classification of Civilization Collections in 2001, and 5) Provisional Regulation on Civilization Auctioning in 2003. Based on the analysis of these sources, this study deduced implications in terms of Chinese old and rare books management such as the necessity to give considerations to 1) the importance of old and rare books management policy, 2) nationwide old and rare books management, 3) expansion of eduction and training of human resources, 4) establishment of institution specializing in old and rare books, and 5) special management of science of Chinese medicine.

• Journal of Korean Library and Information Science Society
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• v.43 no.3
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• pp.143-163
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• 2012

In order to convert a thesaurus described by a person to ontology, the first step is to translate the thesaurus to the ontology by using SKOS, which is suitable for conversion to ontology and was chose an international standard by W3C. SKOS is suitable for converting thesaurus or subject headings or classification system to ontology, but we need a web language to describe an ontology as RDF/XML. RDF/XML is so difficult to read and write that we can need RDFa embedded in HTML document or Turtle, which is more easily describable and readable. Along with description using SKOS, this research has experimentally constructed the ontology by using ontology construction program $Prot{\acute{e}}g{\acute{e}}$ 4.2. In addition to basic concept relationships of thesaurus like equivalent relationship, hierarchical relationships, association relationships transitive hierarchical relationships are included suggested by SKOS in this research.

• KIPS Transactions on Software and Data Engineering
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• v.5 no.7
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• pp.327-332
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• 2016

This study is a leading research project to develop an automatic grade decision making algorithm of a 6-years-old fresh ginseng. For this work, we developed a Ginseng image acquiring instrument which can take 4-direction's images of a Ginseng at the same time and obtained 245 jingen images using the instrument. The 12 parameters were extracted for each image by a manual way. Lastly, 4 parameters were selected depending on a Ginseng grade classification criteria of KGC Ginseng research institute and a survey result which a distribution of averaging 12 parameters. A pattern recognition classifier was used as a support vector machine, designed to "k-class classifier" using the OpenCV library which is a open-source platform. We had been surveyed the algorithm performance(Correct Matching Ratio, False Acceptance Ratio, False Reject Ratio) when the training data number was controlled 10 to 20. The result of the correct matching ratio is 94% of the $1^{st}$ ginseng grade, 98% of the $2^{nd}$ ginseng grade, 90% of the $3^{rd}$ ginseng grade, overall, showed high recognition performance with all grades when the number of training data are 10.

• Journal of the Korean Society for Library and Information Science
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• v.49 no.3
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• pp.371-392
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• 2015

This research attempted to provide new philosophical perspective to be taken in the public libraries as an institution which should support the social inclusion in the multicultural society. As deepening on dichotomous system of culture in modern society, It is referred to the need for an intercultural discourse on mulitcultural services in the public libraries. The process of social Integration suggested by Esser indicated the interactive transformation between actors and society. The conception serves the standard perspective on immigrants. Accordingly, This research analyzed a multicultural program of public libraries based on the classification of policy about immigrants by Castles. And it is based on the intercultural philosophy of Mall, It suggested the roles of public libraries in social integration and the process to support immigrants through the framework by Esser.

• Journal of the Korean Society for Library and Information Science
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• v.53 no.4
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• pp.373-397
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• 2019

Recent disasters are a complex and growing trend. In order to effectively prepare for and respond to disasters that occur without notice, it is very important to use scientific information related to disaster and safety in addition to the standardized disaster safety information that is used. In this paper, we searched and selected major journals in the field of disaster & safety and conducted various network analysis studies using the classification scheme for development of integrated metadata for disaster & safety information developed through Disaster & Safety Information Sharing Platform R&D project as well as KSCD. Also, we have constructed and analyzed citation network, co-authorship network and keyword network through data identification and preprocessing of research paper contents. As a result of this study, based on the network constructed by information analysis unit, the network structure between core domestic and foreign journals, major research institutes, core keywords and individual information by disaster & safety type was identified in detail, and the analysis results were presented on a case-by-case basis.

• Journal of Microbiology and Biotechnology
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• v.21 no.4
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• pp.347-358
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• 2011

Fomitopsis palustris, a brown-rot basidiomycete, causes the most destructive type of decay in wooden structures. In spite of its great economic importance, very little information is available at the molecular level regarding its complex decay process. To address this, we generated over 3,000 expressed sequence tags (ESTs) from a cDNA library constructed from F. palustris. Clustering of 3,095 high-quality ESTs resulted in a set of 1,403 putative unigenes comprising 485 contigs and 918 singlets. Homology searches based on BlastX analysis revealed that 78% of the F. palustris unigenes had a significant match to proteins deposited in the nonredundant databases. A subset of F. palustris unigenes showed similarity to the carbohydrateactive enzymes (CAZymes), including a range of glycosyl hydrolase (GH) family proteins. Some of these CAZyme-encoded genes were previously undescribed for F. palustris but predicted to have potential roles in biodegradation of wood. Among them, we identified and characterized a gene (FpCel45A) encoding the GH family 45 endoglucanase. Moreover, we also provided functional classification of 473 (34%) of F. palustris unigenes using the Gene Ontology hierarchy. The annotated EST data sets and related analysis may be useful in providing an initial insight into the genetic background of F. palustris.

• Journal of Fashion Business
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• v.19 no.5
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• pp.48-62
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• 2015

The purpose of the study was to investigate how the Classification of the Joseon Dynasty's Beauty characteristics were expressed in a TV documentary focusing ona Re-mediation theory. The methods of study comprised of library research, Internet search, and using TV documentary program case studies. The work this Researcher makeup in the manufacture from the documentary in which the methods the Joseon. Dynasty expressed were selected. The literature, and preceding research, were referred to as a way to help organize the Joseon Dynasty's 'gi-saeng Hwang Jin-Hee', 'woman of royal family', and way of make-up of 'sadae-bu lady'. The TV documentary programs selected were 'MBC special' and '2 parts of channel A documentary special'. First, the improvisation of nature and simultaneity expressed in the Joseon Dynasty's usage of make-up is shown through the interview form reflecting the make-up tools and age direction of the scenes or expert. Second, the interactivity and reality are well seen through the row equivalent in which the model seems to directly use the dressing demonstration of the expert and cosmetics material. Third, the cultural expandability and unexpectedness show through the production of situations which are viewed from the explanation of the narration and letter subtitles and drama.