• Title/Summary/Keyword: Level Shift

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Local and global governance of emerging technologies and risk (글로벌 시대의 기술혁신과 리스크 거버넌스를 위한 의사결정구조의 변화)

  • Suh, Jee-Hyun;Won, Dong-Kyu
    • Proceedings of the Korea Contents Association Conference
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    • 2007.11a
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    • pp.183-187
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    • 2007
  • During the recent decades in democratic and industrialized countries, government policies for governing technological innovation and risks to environment and human health have undergone significant changes. The shift from a top-down legislative approach to a more inclusive and deliberative atmosphere is, putatively the most prominent change. Such a move is often described as a move from government to governance. In the governance of technology and risk, public engagement has been a major strategy in technology decision-making process. This article aims to look into the changes in the procedural modes of technology decision-making process. It discusses the main viewpoints that have been placed on the basis of such a move. Also, it further relates the changes in local decision-making process to science and technology decision-making at global level. It argues that the democratic and reflexive trends in local science and technology decision-making will be the basis upon which to shape and respond to global governance system: while international decision-making process would require accountability in integrating different values and rationalities, such accountability may be sustained and reinforced depending on the robustness of the local decisions and social choices.

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A new approach to quantify paraquat intoxication from postmortem blood sample by using 1H qNMR method

  • Hong, Ran Seon;Cho, Hwang Eui;Kim, Dong Woo;Woo, Sang Hee;Choe, Sanggil;Kim, Suncheun;Hong, Jin Tae;Moon, Dong Cheul
    • Journal of the Korean Magnetic Resonance Society
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    • v.17 no.1
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    • pp.40-46
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    • 2013
  • For a case study of suspected paraquat intoxication, we developed a simple and rapid method of $^1H$ qNMR to determine the mili-molar amount of paraquat in postmortem blood samples. There were no interfering signals from endogenous compounds in the chemical shift of paraquat and diquat (internal standard). The amount of sample used ranged from 0.25 mM to 10.0 mM. Diquat, which has similar physicochemical properties with paraquat, was chosen as an internal standard. The NMR experimental conditions, relaxation delay time and CPMG spin-echo pulse sequence were optimized. The developed method was validated in terms of specificity, accuracy, precision, matrix effect, recovery, limit of detection (LOD), and low limit of quantification (LLOQ). The proposed qNMR method provided a simple and rapid assay for the identification and quantification of the quaternary ammonium herbicide, "paraquat" in postmortem blood samples. This method was tested by using the blood from the heart of a man who was intoxicated with paraquat. In this particular case, the level of paraquat was 1.07 mM in the blood. For the determination of quaternary ammonium herbicides, qNMR could also be used to provide a better understanding of the currently available techniques.

A Quantitative Analysis on the NSC(Nature, Science, Cell) Publications of Korean Researchers (Nature, Science, Cell지(誌)에 게재된 한국인 과학자의 논문현황 분석)

  • Heo, Jeong-Eun;Kim, Hae-Do;Choi, Tae-Jin;Kim, Seong-Baek;Jo, Yeong-Don;Kim, In-Ho
    • Journal of Korea Technology Innovation Society
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    • v.9 no.3
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    • pp.558-577
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    • 2006
  • With the rapid shift to a knowledge-based economy, science and technology (S&T) is considered as the principle drivers in a nation's competitiveness. All countries are focused on upgrading the level of their S&T of nations and strengthening their national competitiveness. With these factors in mind, Korea has increased its support of national research and development (R&D). As a result of this added support, Korea S&T has made great strides. This improvement can be seen in the drastic increase in the number of Korean researchers who have been published in Nature, Science and Cell (NSC), three top journals in the fields of S&T. This study is a quantitative analysis on the NSC Publications of Korean researchers. The purpose of this study is to derive research policy suggestions to improve Korea's national competitiveness in S&T.

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Multi-code Biorthogonal Code Keying with Constant Amplitude Coding Combined with $Q^{2}PSK$ to Increase Bandwidth Efficiency (정 진폭 부호화된 Multi-code Biorthogonal Code Keying시스템에서 대역폭 효율 개선을 위해 $Q^{2}PSK$를 이용하는 방안)

  • Kim Sung-Pil;Kim Myoung-Jin
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.31 no.5A
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    • pp.484-492
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    • 2006
  • A multi-code biorthogonal code keying(MBCK) system consists of multiple waveform coding block, and the sum of output codewords is transmitted. Drawback of MBCK is that it requires amplifier with high linearity because its output symbol is multi-level. MBCK with constant amplitude preceding blcok(CA-MBCK) has been proposed, which guarantees sum of orthogonal codes to have constant amplitude. Redundant bits of CA-MBCK for constant amplitude coding are not only used to make constant amplitude signal but also used to improve the bit error rate(BER) performance at receiver. In this paper, we proposed a transmission scheme which combine CA-MBCK with $Q^{2}PSK$ to improve bandwidth efficiency of CA-MBCK. The BER performance of the scheme is same that of CA-MBCK in additive white gaussian noise(AWGN). And we showed that BER performance of the proposed system can be improved using redundant bits of constant amplitude preceding.

Suppression of CYP1A1 Expression by Naringenin in Murine Hepa-1c1c7 Cells

  • Kim, Ji-Young;Han, Eun-Hee;Shin, Dong-Weon;Jeong, Tae-Cheon;Lee, Eung-Seok;Woo, Eun-Rhan;Jeong, Hye-Gwang
    • Archives of Pharmacal Research
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    • v.27 no.8
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    • pp.857-862
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    • 2004
  • Naringenin, dietary flavonoid, is antioxidant constituents of many citrus fruits. In the present study, we investigated the effect of naringenin on 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible CYP1 A 1 gene expression in mouse hepatoma Hepa-1c1c7 cells. Naringenin alone did not affect CYP1A1-specific 7-ethoxyresorufin O-deethylase (EROD) activity. In contrast, the TCDD-inducible EROD activities were markedly reduced upon concomitant treatment with TCDD and naringenin in a dose dependent manner. TCDD-induced CYP1A1 mRNA level was also markedly suppressed by naringenin. A transient transfection assay using dioxin-response element (DRE)-linked luciferase and electrophoretic mobility shift assay revealed that naringe-nin reduced transformation of the aryl hydrocarbons receptor(AhR) to a form capable of specif-ically binding to the DRE sequence in the promoter of the CYP1A1 gene. These results suggest the down regulation of the CYP1A1 gene expression by either naringenin in Hepa-1c1c7 cells might be antagonism of the DRE binding potential of nuclear AhR.

A Study on Data Sharing Codes Definition of Chinese in CAI Application Programs (CAI 응용프로그램 작성시 자료공유를 위한 한자 코드 체계 정의에 관한 연구)

  • Kho, Dae-Ghon
    • Journal of The Korean Association of Information Education
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    • v.2 no.2
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    • pp.162-173
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    • 1998
  • Writing a CAI program containing Chinese characters requires a common Chinese character code to share information for educational purposes. A Chinese character code setting needs to allow a mixed use of both vowel and stroke order, to represent Chinese characters in simplified Chinese as well as in Japanese version, and to have a conversion process for data exchange among different sets of Chinese codes. Waste in code area is expected when vowel order is used because heteronyms are recognized as different. However, using stroke order facilitates in data recovery preventing duplicate code generation, though it does not comply with the phonetic rule. We claim that the first and second level Chinese code area needs to be expanded as much as academic and industrial circles have demanded. Also, we assert that Unicode can be a temporary measure for an educational code system due to its interoperability, expandability, and expressivity of character sets.

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Utilization Outlook of Medical Big Data in the Cloud Environment (클라우드 환경에서 의료 빅데이터 활용 및 전망)

  • Han, Jung-Soo
    • Journal of Digital Convergence
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    • v.12 no.6
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    • pp.341-347
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    • 2014
  • Among methods of the big data process, big data process under the cloud environment is becoming a main topic. As part of solving faced problem and strengthening industrial competitiveness in the medical and health industry, discussion on ways to activate big data is actively being conducted. Because the reason is a paradigm shift, saving pressure for increasing health care costs, and increased consumer interest for the level of service. In this paper, we find out the relationship between the cloud and big data. And we are to research and analysis a cloud-based big data case in the medical field. Finally we propose the efficient utilization and future outlook. For the smooth functioning of cloud-based medical big data, we have to solve the problems like infrastructure extension, analysis/application software development, and professional manpower training. In addition, we have to correct insufficient laws maintenance to the Cloud utilization, and improve the security and the recognition to personal information, and solve authority for data centralization.

Investigation of Feasibility of Tunneling Field Effect Transistor (TFET) as Highly Sensitive and Multi-sensing Biosensors

  • Lee, Ryoongbin;Kwon, Dae Woong;Kim, Sihyun;Kim, Dae Hwan;Park, Byung-Gook
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.17 no.1
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    • pp.141-146
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    • 2017
  • In this letter, we propose the use of tunneling field effect transistors (TFET) as a biosensor that detects bio-molecules on the gate oxide. In TFET sensors, the charges of target molecules accumulated at the surface of the gate oxide bend the energy band of p-i-n structure and thus tunneling current varies with the band bending. Sensing parameters of TFET sensors such as threshold voltage ($V_t$) shift and on-current ($I_D$) change are extracted as a function of the charge variation. As a result, it is found that the performances of TFET sensors can surpass those of conventional FET (cFET) based sensors in terms of sensitivity. Furthermore, it is verified that the simultaneous sensing of two different target molecules in a TFET sensor can be performed by using the ambipolar behavior of TFET sensors. Consequently, it is revealed that two different molecules can be sensed simultaneously in a read-out circuit since the multi-sensing is carried out at equivalent current level by the ambipolar behavior.

Low-Informative Region Detection based on Multi-Layer Perceptron for Automatical Insertion of Virtual Advertisement in Sports Image (스포츠 영상 내에서 자동적인 가상 광고 삽입을 위한 다층퍼셉트론 기반의 저정보 영역 검출)

  • Jung, Jae-Young;Kim, Jong-Ha
    • Journal of Digital Contents Society
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    • v.18 no.1
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    • pp.71-77
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    • 2017
  • Virtual advertisement is an advertising technique that using computer graphic in a media production such as a sports image for inserting product image, logo, advertising slogan, etc. Recently, the image insertion of virtual advertisement is actively spreading due to the satisfaction of technical element for the image insertion of virtual advertisement in sports advertisement by increasing of the image processing technology and the computing performance. In addition, image processing technology for automatic insertion has become an important research field in the virtual advertisement field. In this paper, we propose the method of extracting less-informative region by using image processing technique and machine learning to insert a virtual advertisement automatically in sports image. The proposed method analyzes the brightness level of image through the histogram and extracts the less-informative region using the machine learning method.

A Study on Parallel Operation of PWM Converter for Auxiliary Power Supply of High Speed Train (고속전철 보조전원장치용 PWM 컨버터의 병렬운전에 관한 연구)

  • Kim, Yeon-Chung;O, Geun-U;Won, Chung-Yeon;Choe, Jong-Muk;Gi, Sang-U
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.37 no.6
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    • pp.64-72
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    • 2000
  • This paper deals with the parallel operation of two PWM converters for auxiliary block of high speed train. The parallel operation of AC/DC PWM converter controlled by 3-level PWM switching method to operate switching devices to realize a high power factor and reduce the primary side of the transformer current harmonics is proposed. In this paper, it is presented the phase shift technique between two converters switching phase, solution to eliminate the coupling effects due to the transformer and zero crossing detection method for synchronized with the source and controller. Experimental results for laboratory system with TMS320C31 microprocessor and 10[kVA]PWM converter confirm the validity of the proposed algorithm.

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