• The Transactions of the Korean Institute of Electrical Engineers C
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• v.52 no.5
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• pp.201-205
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• 2003

We synthesized dendrimers containing light switchable units, azobenzene group. And the dendrimer containing 48 pyridinepropanol functional end group, which could form a complex structure with metal ions was synthesized. To apply to the molecular level devices or data storage system using Langmuir-Blodgett(LB) film, we firstly investigated the monolayer behavior using the surface pressure-area($\pi$-A) isotherms at air-water interface. And then the surface pressure shift of monolayer by light irradiation was also measured to the dendrimer with azobezene group. As a result, the monolayer of dendrimer with azobenzene group showed the reversible photo-switching behavior by the isomerization of azobenzene group in their periphery. The samples for electrical measurement were fabricated to two types which were pure dendrimer with pyridinepropanol group and its complexes with $Pt^4+$ ions by LB method. We have studied the electrical properties of the ultra thin dendrimer LB films investigated by the current-voltage(I-V) characteristics of Metal/Dendrimer LB films/Metal(MIM) structure. And we have investigated different results in the surface activity at the air-water interface as well as the electrical properties for the monolayers of pure dendrimer with pyridinevopanol group and its complex with $Pt^4+$ ions. In conclusion, it is demonstrated that the metal ion around dendrimer with pyri야nepropanol group can contribute to make formation of network structure among dendrimers and it result from the change of electrical properties. This results suggest that the dendrimers with azobenzene group and pvridinedropanol group can be applied to high efficient nano-device of molecular level.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.52 no.5
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• pp.201-201
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• 2003

We synthesized dendrimers containing light switchable units, azobenzene group. And the dendrimer containing 48 pyridinepropanol functional end group, which could form a complex structure with metal ions was synthesized. To apply to the molecular level devices or data storage system using Langmuir-Blodgett(LB) film, we firstly investigated the monolayer behavior using the surface pressure-area($\pi$-A) isotherms at air-water interface. And then the surface pressure shift of monolayer by light irradiation was also measured to the dendrimer with azobezene group. As a result, the monolayer of dendrimer with azobenzene group showed the reversible photo-switching behavior by the isomerization of azobenzene group in their periphery. The samples for electrical measurement were fabricated to two types which were pure dendrimer with pyridinepropanol group and its complexes with $Pt^4+$ ions by LB method. We have studied the electrical properties of the ultra thin dendrimer LB films investigated by the current-voltage(I-V) characteristics of Metal/Dendrimer LB films/Metal(MIM) structure. And we have investigated different results in the surface activity at the air-water interface as well as the electrical properties for the monolayers of pure dendrimer with pyridinevopanol group and its complex with $Pt^4+$ ions. In conclusion, it is demonstrated that the metal ion around dendrimer with pyri야nepropanol group can contribute to make formation of network structure among dendrimers and it result from the change of electrical properties. This results suggest that the dendrimers with azobenzene group and pvridinedropanol group can be applied to high efficient nano-device of molecular level.

• Korean Journal of Applied Biomechanics
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• v.28 no.1
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• pp.9-18
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• 2018

Objective: This study aimed to analyze how the upright body type exercise program affected body balance and record of archers. This study aimed to prove the effectiveness of upright body type exercise, on this basis, in enhancing the performance of archery players. Method: A total of 14 archers (7 men and 7 women) in B Metropolitan City who had ${\geq}4years$ of career in archery and were given explanation of its contents and purpose before giving spontaneous consent to the experiment were enrolled in the study. The upright body type exercise program was implemented thrice a week for 12 weeks, with higher exercise intensity with time. A resistive pressure sensor, Gaitview AFA-50, was used to measure the foot plantar pressure distribution and analyze quantitative information concerning variation in posture stability and weight shift in dynamic balance of foot plantar pressure in shooting and static balance of plantar pressure with the eyes open and closed and the change in archery record accompanying the change in body balance. Results: As for the differences in foot plantar pressure between before and after participation in the upright body type exercise program, there was no significant difference in static balance of foot plantar pressure with the eyes open, and there was statistically significant difference at the ${\alpha}=.05$ significance level in static balance of foot plantar pressure with the eyes closed or in dynamic balance of foot plantar pressure in shooting. There was statistically significant difference at the ${\alpha}=.05$ significance level in archery record. Conclusion: The upright body type exercise program had positive effects on static and dynamic balance of foot plantar pressure by allowing archers to experience less body sway and physical imbalance in shooting with closed eyes and positive effects on archery record. Thus, the program is expected to help archers correct their posture and perform better.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.27 no.1
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• pp.23-37
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• 2017

Objectives : This study was conducted to evaluate the level of exposure to volatile organic compounds (VOCs) among workers handling rust preventive oils. Methods : A total of 30 bulk samples and 54 personal air samples were collected using diffusive samplers at 22 workplaces handling rust preventive oils in Daegu and Gyongsangbuk-do Province from March to October 2013. We also investigated detailed information on the related work conditions, such as kinds of products, handling methods, local exhaustive ventilation systems, and the status of the wearing personal protective equipment. All bulk samples and air samples were analyzed using gas chromatography mass spectrometry (GC-MS) to identify components to which workers potentially were exposed. Quantitative airborne concentrations of VOCs were confirmed using gas chromatography with flame ionized detectors. Results : In terms of qualitative analyses for the 30 bulk samples, we found carcinogenic, mutagenic and reproductive toxic(CMR) substances such as butane(carcinogenic Group 1A, mutagenic Group 1B), butoxy ethanol(carcinogenic Group 2), cumene (carcinogenic Group 2), ethyl benzene(carcinogenic Group 2), methyl isobutyl ketone(carcinogenic Group 2) and toluene (reproductive toxic, Group 2). As a result of full-shift based personal air samples, eight substances such as n-hexane, n-heptane, octane, nonane, decane, toluene, ethyl benzene and xylene were detected. Among them, n-hexane and n-heptane were detected in all of 54 air samples with $13.13mg/m^3$ and $8.61mg/m^3$ of maximum concentration, respectively. The level of airborne concentration from all of samples were bellow the occupational exposure limit in Korea. Conclusions : Based on the results of this study, workers handling rust preventive oils could be exposed to CMR substances contained in rust preventive oils and n-hexane and n-heptane were found as the most frequent sources of VOC exposure.

• Archives of Pharmacal Research
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• v.29 no.7
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• pp.570-576
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• 2006

Phytoestrogen biochanin A is an isoflavone derivative isolated from red clover Trifolium pratense with anticarcinogenic properties. This study examined the action of biochanin A with the carcinogen activation pathway that is mediated by the aryl hydrocarbon receptor (AhR) in MCF-7 breast carcinoma cells. Treating the cells with biochanin A alone caused the accumulation of CYP1A1 mRNA and an increase in CYP1A1-specific 7-ethoxyresorufin O-deethylase (EROD) activity in a dose dependent manner. A concomitant treatment with 7,12-dimethylbenz[a]anthracene (DMBA) and biochanin A markedly reduced the DMBA-inducible EROD activity and CYP1A1 mRNA level. In addition, the biochanin A treatment alone activated the DNA-binding capacity of the AhR for the dioxin-response element (DRE) of CYP1A1, as measured by the electrophoretic-mobility shift assay (EMSA). EMSA revealed that biochanin A reduced the level of the DMBA-inducible AhR-DRE binding complex. Furthermore, biochanin A competed with the prototypical AhR ligand, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), for binding to the AhR in an isolated rat cytosol. The biochanin A competitively inhibited the metabolic activation of DMBA, as measured by the formation of the DMBA-DNA adducts. These results suggest that biochanin A may thus be a natural ligand to bind on AhR. Therefore, biochanin A may be due to act an antagonist/agonist of the AhR pathway.

• Archives of Pharmacal Research
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• v.28 no.12
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• pp.1350-1357
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• 2005

Nuclear factor kappa B (NF-$\kappa$B) regulates the expression of multiple cytokines, chemokines, and cell adhesion molecules that are involved in the pathogenesis of asthma. We investigated the anti-asthmatic effects and the mechanism of action of DA-9201, an extract of the black rice, in a mouse model of asthma. Mice immunized with ovalbumin (OVA) were administered with DA-9201 (30, 100 or 300 mg/kg) or dexamethasone (DEXA, 3 mg/kg) for 2 weeks and challenged with aerosolized OVA during the last 3 days. Anti-asthmatic effects were assessed by means of enhanced pauses, level of total lgE and Th2 cytokines in plasma or bronchoalveolar lavage fluid (BALF), the percentage of eosinophils in BALF, and histopathological examination. The expression of NF-$\kappa$B in nuclear and cytoplasmic fraction and its DNA-binding activity in lung tissues were analyzed by means of Western blotting and electrophoretic gel mobility shift assay (EMSA), respectively. DA-9201 significantly reduced airway hyperrespon-siveness (AHR), total lgE level in plasma and BALF, IL-4, IL-5, and IL-13 levels in BALF, and the percentage of eosinophils in BALF. Tissue inflammation was significantly improved by DA­9201 treatment. In addition, DA-9201 dramatically suppressed the expression of NF-$\kappa$B and its DNA-binding activity. These results suggest that DA-9201 may be useful for the treatment of asthma and its efficacy is related to suppression of NF-$\kappa$B pathway.

• Korean Journal of Community Nutrition
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• v.28 no.3
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• pp.220-234
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• 2023

Objectives: This study aimed to assess the adherence to dietary guidelines among college students in the post-COVID-19 era and examine the changes in their dietary habits as the learning environment transitioned from remote to in-person classes. Methods: We conducted a survey involving 327 college students in Daejeon from March to April 2023. The survey questionnaires included various factors, including age, gender, type of residence, frequency of use of delivery food, convenience food, and eating out. In addition, we investigated the extent of adherence to the dietary guidelines for Koreans and the degree of dietary changes following the post-COVID-19 shift in class format were investigated. For comparative analysis of the level of adherence to dietary guidelines in relation to dietary habit changes, an ANOVA and a post hoc Scheffe test were employed. We also performed a multiple linear regression analysis to identify dietary factors influencing the level of adherence to dietary guidelines. Results: The study revealed a high rate of convenience food consumption and a low rate of homemade food intake among students. There was a marked increase in the consumption of processed foods, convenience foods, dining out, sweet foods, high-fat fried foods, beverages, and alcohol following the transition from online to in-person classes. When examining adherence to Korean dietary guidelines, the highest scored practice was 'Hydration', and the lowest was 'Breakfast habit'. Increased consumption of convenience foods, late-night snacks, and dining out were negatively correlated with adherence levels to dietary guidelines, specifically correlating with 'Healthy weight', 'Hydration', 'Breakfast habit', and the total score of adherence. The adoption of 'regular meals' was positively associated with increased adherence levels to dietary guidelines. Conclusions: The transition from remote to in-person classes post-COVID-19 led to increased intake of convenience foods, dining out, sweet foods, high-fat fried foods, and alcohol. The rise in convenience food and late-night snack consumption negatively influenced several aspects of the dietary guidelines adherence, thereby suggesting the need for strategies to encourage healthy dietary habits among college students.

• Geomechanics and Engineering
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• v.36 no.4
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• pp.367-380
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• 2024

Investigations has shown that the correct estimation of the effective amplification period is as important as the amplification value itself. It gets more important in 2D basins. This study presents a quantitative coefficient for consideration of the nonlinearity effect in terms of amplification value and the shift in its period which is missing or ineffectively considered in the previous studies. To attain this goal, by the application of a time domain fully nonlinear method, the deviation of the more common equivalent linear results from the basin nonlinear behavior under strong ground motions is investigated quantitatively. Also, despite the increase in the damping ratio, the possibility of the increase in the amplification due to the increase in motion strength is shown. To make the results useful in engineering practice, by introducing nonlinearity ratio, the effect of the nonlinearity is quantitatively estimated for two soft and stiff clayey basins with three different depths under a set of motions scaled to two target spectrum. Results show that at the 100 m depth soft clayey basin, while the nonlinearity ratio shows a 35% deviation at the basin edge part under DD1 motion level, its effect moves to the central part with 20% effect under DD3 motion level. By the increase in depth to 150 m, the results show a decrease in the overall effect of the nonlinear behavior for both clay types. At this depth, the nonlinearity ratio gives a 30% and 17% difference on a limited distance from outcrop at the soft clayey basin under DD1 and DD3 motion levels, respectively. At the 30 m depth basins, the nonlinearity ratio shows up to 25% difference for different cases. The presented ratio would be introduced as nonlinearity coefficients for consideration of the nonlinearity effects in the codes. The presented quantitative margins will help the designer to have a better understanding of the amplification period change because of nonlinearity over 2D basin surface.

• Safety and Health at Work
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• v.15 no.1
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• pp.53-58
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• 2024

Background: As social distancing persists and interest in work-life balance grows, more companies are adopting flexible work policies. While there have been studies on sleep disorders associated with different types of work, such as shift work, research exploring the relationship between flexible work schedules and sleep disorders is still limited, particularly among Korean workers. Methods: We performed a secondary analysis of the 6th Korean Working Conditions Survey, focusing on 31,243 paid workers out of a total of 50,538 participants. We defined flexible workers as those who set their own working hours. Sleep disorders were divided into three categories: 'difficulty falling asleep,' 'frequent waking during sleep,' and 'waking up feeling exhausted and fatigued.' Using scores derived from three specific symptoms, the Minimal Insomnia Symptoms Scale (MISS) was calculated to assess the prevalence of insomnia. We used chi-square tests to analyze demographic and job-related differences. A multivariate logistic regression analysis was employed to identify any relationship between flexible work schedules and sleep disorders. Results: Significant differences were found between flexible and non-flexible workers regarding age, income level, education level, and job type. Flexible workers reported sleep-related symptoms significantly more often. The odds ratio for insomnia was 1.40 (95% CI 1.21-1.61). For males, the odds ratio was 1.68 (1.36-2.08). Conclusion: This study establishes a correlation between flexible work schedules and sleep disorders among Korean salaried workers. Potential causes could include changes in circadian rhythm, increased work demands, and extended working hours. To precisely determine causality and associated diseases, further research is required.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.2
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• pp.185-205
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• 2017

The purpose of this research is to examine the relationship between the adult attachment of married employees, their job motivation and marital relationship. For this purpose, a questionnaire survey was carried out with 370 married employees in the Chungnam area as the target from Sep. 10 to Oct. 14, 2016. The collected data was analyzed using SPSS 23.0 using descriptive statistical analysis, the independent sample T-test, ANOVA analysis, Pearson correlation, and structural equation analysis. First, significant differences were revealed in the level of attachment avoidance, satisfaction with the marriage relationship, and job motivation according to the age group, in the level of attachment avoidance and satisfaction with the marriage relationship according to the education level, in the level of attachment avoidance and satisfaction with the marriage relationship according to the marriage period, in job motivation according to the position, in satisfaction with the marriage relationship according to the average household income, and in satisfaction with the marriage relationship according to the work shift pattern. Second, although a significant negative correlation appeared between attachment anxiety and attachment avoidance, a significant positive correlation was found between attachment avoidance and job motivation. Also, although a significant negative correlation appeared between attachment avoidance and marital relationship, a significant positive correlation was found between job motivation and marital relationship. Third, to examine the mediating effect of satisfaction with the marital relationship on the relationship between adult attachment and job motivation, a structural equation analysis was carried out. As a result, the indirect effect of attachment anxiety on job motivation turned out to be significant and its complete mediating effect was confirmed. This suggests that when developing programs to improve job motivation within the workplace or consultative interventions for the enhancement of marital relationships, the above characteristics of individuals should be taken into consideration.