• Title/Summary/Keyword: Lee Sam

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Studies on the Enzymatic Partial Hydrolysis of Soybean Protein Isolates (효소처리에 의한 분리대두 단백질의 부분 가수분해에 관한 연구)

  • Lee, Cherl-Ho;Kim, Chan-Shick;Lee, Sam-Pin
    • Korean Journal of Food Science and Technology
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    • v.16 no.2
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    • pp.228-234
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    • 1984
  • A partial hydrolysis of soybean protein isolate was carried out by using pepsin and trypsin. The degree of hydrolysis was evaluated by chemical analysis, viscometric measurements and gel electrophoresis. The functional properties of the hydrolyzates such as flow behavior, emulsion properties and foaming properties were evaluated. A selective hydrolysis of 11S protein fraction by pepsin was observed from the SDS-PAG electrophoresis. The changes in the molecular weight distribution by different conditions of enzyme hydrolysis were evaluated. The changes in the intrinsic viscosity of the protein hydrolylate by reaction time were highly correlated to the contents of TCA soluble protein and 0.03 M $CaCl_2$ soluble nitrogen. The degree of hydrolysis ($DH_{TCA}$, $DH_{Ca}$) were used to evaluate the effect of enzyme treatment on the functional properties of the hydrolyzate. The apparent viscosity and emulsion capacity and stability of the protein solution decreased as DH increased, while the foaming capacity increased linearly with the increasing DH.

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A Comparative Study of GABA, Glutamate Contents, Acetylcholinesterase Inhibition and Antiradical Activity of the Methanolic Extracts from 10 Edible Plants (10가지 식용식물 추출물의 가바, 글루탐산 함량, 아세틸콜린에스테라제 억제 및 라디컬 소거능 비교)

  • Jung, Yeon-Seop;Park, Sung-Jin;Kim, Ji-Eun;Yang, Seun-Ah;Park, Jung-Hyun;Kim, Jung-Hyun;Jhee, Kwang-Hwan;Lee, Sam-Pin;Lee, In-Seon
    • Korean Journal of Food Science and Technology
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    • v.44 no.4
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    • pp.447-451
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    • 2012
  • In order to investigate the efficacies for cognitive function of edible plants, we measured the inhibitory effects of acetylcholinesterase(AChE) activity, radical scavenging activities, and the contents of GABA and glutamate in the plant extracts. Among the plant extracts, Schizandra chinensis contained the highest GABA 14.8 mg/g and the extracts of Cnidium officinale and Polygonum multiflorum also had a relatively high GABA. On the other hand, plant extracts except, Acorus gramineus, showed similar glutamate contents. S. chinensis, Hovenia dulcis, Thuja orientalis, and Eleutherococcus senticosus exhibited high inhibition against AChE activities at about 18-33% at 1 mg/mL. In addition, strong radical scavenging activities were also detected in those extracts which showed high AChE inhibition. Taken together, H. dulcis, T. orientalis, E. senticosus, and S. chinensis could be effective resources for enhancing cognitive function. Further, it was suggested that the AChE inhibitory activities of plant extracts might be related to antioxidative activity.

Design and Evaluation of a Lung Assist Device for Patients with Acute Respiratory Syndrome using Hollow Fiber Membranes (중공사 막을 이용한 급성호흡곤란증후군 환자용 폐 보조 장치의 설계와 평가)

  • Lee, Sam-Cheol;Kwon, O-Sung;Kim, Ho-Cheol;Hwang, Young-Sil;Lee, Hyun-Cheol
    • Membrane Journal
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    • v.15 no.3
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    • pp.224-232
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    • 2005
  • The use of the lung assist device (LAD) would be well suited for acute respiratory failure (ARF) patients, combining the simplicity of mechanical ventilation with the ability of extracoporeal membrane oxygenators (ECMO) to provide temporary relief for the natural lungs. This study's specific attention was focused on the effect of membrane vibration in the LAD. Quantitative experimental measurements were performed to evaluate the performance of the device, and to identify membrane vibration dependence on blood hemolysis. We tried to decide upon excited frequency band of limit hemolysis when blood hemolysis came to through a membrane vibration action. The excited frequency of the module type 5, consisted of 675 hollow fiber membranes, showed the maximum gas transfer rate. We concluded that the maximum oxygen transfer rate seemed to be caused by the occurrence of maximum amplitude and the transfer of vibration to hollow fiber membranes. It was excited up to $25{\pm}5$ Hz at each blood flow rate of module type 5. We found that this frequency became the 2nd mode resonance riequency of the flexible in blood flow. Blood hemolysis was low at the excited frequency of $25{\pm}5$ Hz. Therefore, we decided that limit hemolysis frequency of this LAD was $25{\pm}5$ Hz.

Risk Factors for Predicting Hypoxia in Adult Patients Undergoing Bronchoscopy under Sedation

  • Choi, Ji Soo;Lee, Eun Hye;Lee, Sang Hoon;Leem, Ah Young;Chung, Kyung Soo;Kim, Song Yee;Jung, Ji Ye;Kang, Young Ae;Park, Moo Suk;Chang, Joon;Kim, Young Sam
    • Tuberculosis and Respiratory Diseases
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    • v.83 no.4
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    • pp.276-282
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    • 2020
  • Background: Flexible bronchoscopy is one of the essential procedures for the diagnosis and treatment of pulmonary diseases. The purpose of this study was to identify the risk factors associated with the occurrence of hypoxia in adults undergoing flexible bronchoscopy under sedation. Methods: We retrospectively analyzed 2,520 patients who underwent flexible bronchoscopy under sedation at our tertiary care university hospital in South Korea January 1, 2013-December 31, 2014. Hypoxia was defined as more than 5%-point reduction in the baseline percutaneous oxygen saturation (SpO2) or SpO2 <90% for >1 minute during the procedure. Results: The mean age was 64.7±13.5, and 565 patients developed hypoxia during the procedure. The mean sedation duration and midazolam dose for sedation were 31.1 minutes and 3.9 mg, respectively. The bivariate analysis showed that older age, a low forced expiratory volume in one second (FEV1), use of endobronchial ultrasound, the duration of sedation, and the midazolam dose were associated with the occurrence of hypoxia during the procedure, while the multivariate analysis found that age >60 (odds ratio [OR], 1.32), a low FEV1 (OR, 0.99), and a longer duration of sedation (>40 minutes; OR, 1.33) were significant risk factors. Conclusion: The findings suggest that patients older than age 60 and those with a low FEV1 tend to develop hypoxia during the bronchoscopy under sedation. Also, longer duration of sedation (>40 minutes) was a significant risk factor for hypoxia.

Development of the Estimation Model on Daily Pollutant Loads for the Nakdong River Basin II. Application of the Model (낙동강 유역에 대한 일별 유달부하량 산정모델개발 II. 모델식의 활용)

  • Yoon, Young-Sam;Yu, Jae-Jeong;Kim, Moon-Soo;Lee, Hae-Jin;Lee, Jun-Bae;Yang, Sang-Yong
    • Journal of Environmental Science International
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    • v.16 no.3
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    • pp.333-345
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    • 2007
  • As analyzed the estimated values of the daily delivery loads from thirteen major side streams such as Naesung-river, Keumho-river, Hwang-river, Nam-river during five years (from 1999 to 2003), the daily BOD inflow into the main stream of Nakdong river in 2003 shows the highest quantity as 31.1 ton and the daily BOD inflows in 1999, 2000, 2001, and 2002 are 26.7 ton, 22.5 ton, 21.0 ton, 25.8 ton, respectively. The daily TN in-flow into the main stream of Nakdong river in 2003 shows also the highest quantity as 64.9 ton and the daily TN inflows in 1999, 2000, 2001, and 2002 are 55.19 ton, 46.27 ton, 39.5 ton, 53.38 ton, respectively. The daily TP inflow into the main stream of Nakdong river in 2003 shows the highest quantity as 2.70 ton likewise and the daily TP inflows in 1999, 2000, 2001, and 2002 are 2.17 ton, 1.87 ton, 1.60 ton, 2.10 ton, respectively The rate of BOD loads from each side main stream into the main stream of Nakdong river shows that the BOD loads of Keumho-river are the highest as the values range from 32.8 % (2002) ${\sim}$ 35.1 % (2003) and the BOD loads of Nam-river, Naesung-river, Hwang-river are high in the order named. The rate of TN loads to the main stream is also similar to the trend of BOD loads. The contribution of the TN loads of Geumho-river to the contamination of the main stream is also the highest having a range from 27.0 % (2002) to 28.8 % (1999) among the main side streams and the TN loads of Naesung-river, Nam-river, and Heachun-river are high in the order named. The rate of TP loads is quite different from the trend of BOD and TN loads. The TP rate of Keumho-river, however, is still the highest as ranging 58.6 % (2002) to 61.7 % (2003) and the river has the biggest portion (over 50%) of the entire pollution to the main stream of Nakdong river.

Default Risk Mitigation Effect of Financial Structure and Characteristic in BOT Project Finance (BOT 프로젝트 파이낸스의 금융구조 및 특성의 채무불이행 위험완화 효과)

  • Jun, Jae-Bum;Lee, Jae-Sue;Lee, Sam-Su
    • Korean Journal of Construction Engineering and Management
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    • v.12 no.2
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    • pp.121-132
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    • 2011
  • One of the advantages of BOT PF(Project Finance) is the government can be protected from risks involved in projects as the private finances, builds, and operates relevant projects. Moreover, the private may avoid outstanding responsibility in case of default thanks to BOT PF's unique financial structure and characteristics. However, despite increasing attention on risk mitigation effect of financial structure and characteristic of BOT PF to default risk with emerging controversies of capital crunch, introduction of IFRS, and contingent liabilities, valuation of default risk mitigation effect caused by financial structure and characteristics of BOT PF still seems sophisticated due to uncertain cash flows, complexly layered contracts, and their interaction. So, this paper is to show the theoretical frame to assess the default risk mitigation effect of financial structure and characteristic of BOT PF with option pricing and related financial economic theories and to provide some meaningful implications. Finally, this research shows that the financial structure and characteristics of BOT PF help mitigate the default risk and default risk mitigation effect increases as change of relevant variables on financial feasibility gets the BOT project less financially feasible.

Variation Characteristics of Irregular Wave Fields around 3-Dimensional Low-Crested-Breakwater (3차원 저마루구조물(LCS) 주변에서 불규칙파동장의 변동특성)

  • Lee, Kwang-Ho;Lee, Jun Hyeong;Jung, Uk Jin;Kim, Do-Sam
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.32 no.2
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    • pp.122-134
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    • 2020
  • On the many coasts of South Korea, including the eastern side, it has been recently increasing the coastal disaster such as the severe coastal erosion and road damage swept away by the wave. As one of the alternatives to prevent the coastal disaster, it has been widely studied the coastal disaster reduction method by the Low-Crested Structure (LCS) in the many countries including several European countries. In this study, the olaFLow model is used to simulate the permeable LCS and wave field of the LCS through the three-dimensional irregular waves numerical analysis on the basis of the previous research. From the numerical analysis, it is evaluated the Hrms, nearshore current and time-averaged turbulent kinetic energy. In addition, the pattern of nearshore current and spatial distribution of time-averaged turbulent kinetic energy are compared with the case of submerged breakwater under the irregular wave fields. As one of significant results, it is confirmed that the pattern of nearshore current is different with the case of submerged breakwater.

Testing for validity of isometric muscle endurance test as an abdominal muscular endurance evaluation methods (복근 지구력 평가 도구로서 등척성 수축 후 버티기 방법의 타당성 비교 검증)

  • Park, Soon-Tae;Hur, Sung-Hoon;Lee, Jang-Kyu;Lee, Jong-Sam
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.2
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    • pp.815-827
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    • 2014
  • The current study was undertaken to verify appropriateness of muscle endurance test at three different angles ($30^{\circ}C$, $40^{\circ}C$, $50^{\circ}C$) of isometric contraction position, and to sought valid and reliable testing method that provide an alternative to sit-ups. Total 92 young and healthy subjects (68 males and 24 females) were recruited, and the following results were obtained. 1. A low correlations in males, but a high correlations in females was found when the comparisons were made between aerobic and muscle endurance capability. 2. Measuring tolerance time, by using isometric contraction was showed a significant correlation with the repetition numbers of sit-ups. 3. The highest correlation was found at 40 inclined degrees of plane, and the lowest correlation was drawn from 50 inclined degrees of plane. Based on these results, it was concluded that measuring tolerance time during maintaining an isometric contraction at 40 inclined degrees of plane is a valid and effective tool for measuring abdominal muscle endurance, and it can be used as an alternative way of sit-up, which potentially risky for inducing many back-associated injuries. Further studies need to be undertaken to determine for optimal angles, that can safely be applied for people of various age groups and physical conditions.

A Study on the Development of Non-PC High-Early-Strength Concrete Without Steam Curing (증기양생이 불필요한 PC부재용 조강형 콘크리트 개발에 관한 연구)

  • Jun, Woo-Chul;Lee, Ji-Hwan;Park, Hee-Gon;Lee, Jae-Sam;Kim, Kyung-Min;Cho, In-Sung
    • Journal of the Korea Institute of Building Construction
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    • v.14 no.2
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    • pp.156-162
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    • 2014
  • This study aims to develop a rapidly hardening type of concrete to achieve the removal of form intensity (more than 10MPa) using the method of curing at room temperature in order to solve some economic environmental problems by omitting the steam curing process involved in producing PC (Precast Concrete). Therefore, this study evaluated a rapidly hardening cement containing a high amunt of C3S, which is very responsive in expressing early intensity, and a rapidly hardening type of concrete which uses some hardening accelerator to increase thehydration reaction of $C_3S$. The results of the experiment on concrete using some hardening accelerator are asfollows. In the slump flow experiment for identifying the liquidity and the air test, the desired values were met. The compression strength showed rapid expression response by 12 hours, and met the desired value within 6~9 hours. Its drying shrinkage value and Autogenous shrinkage value were measured as below ($-754.5{\times}10^{-6}$),and satisfied the requirements. In addition, in the Semi-Adiabatic Temperature Test, it was found that the concrete rose to its peak temperature within 24 hours and then its temperature dropped.

Study on Medium Ingredient Composition for Enhancing Biomass Productionand Anti-potato Common Scab Activity of Streptomyces sp. A020645 as a BCA Candidate (생물제제(BCA) 후보균주인 Streptomyces sp. A020645 의 대량 균체생산 및 항더뎅이병 활성증진을 위한 고체배지 조성에 관한 연구)

  • Lee, Hyang-Burm;Roh, Hyo-Young;Park, Dong-Jin;Lee, So-Keum;Ko, Young-wan;Koh, Jeong-Sam;Kim, Chang-Jin
    • Research in Plant Disease
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    • v.11 no.1
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    • pp.66-71
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    • 2005
  • The effect of medium components such as wheat bran, rice bran, oat meal, and soybean meal as basic ingredients and KH2PO4, glucose, and molasses as additives on mass production and anti-potato common scab activ ity of a streptomycete A020645 strain as a biocontrol agent (BCA) candidate was investigated. Of basicingredients, oat meal was the best one for mass poduction and enhancement of anti-potato common scabactivity. The biomass production of the active strain was more enhanced when 0.1-0.01.% glucose or molassesas additive were added into the basic medium. These information may have important implications in applying for effective formulation of BCA.