• Title/Summary/Keyword: Lee Sam

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A Gene Encoding Endoplasmic Reticulum Resident 29 kDa Protein is Regulated by TSH-Dependently at the Transcription Level (갑상선자극호르몬에 의한 분자\ulcorner페론 ERp29 유전자의 발현)

  • Park, Soo-Jung;Lee, Woong-Hee;Goo, Tae-Won;Yun, Eun-Young;Hwang, Jae-Sam;Kim, Ho;Shong, Min-Ho;Kwon, O-Yu
    • Journal of Life Science
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    • v.10 no.2
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    • pp.150-156
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    • 2000
  • This experiment was performed to evaluate the effect of TSH (thyroid-stimulating) on the ERp29 (endoplasmic reticulum resident 29 kDa protein) gene expression in the rat thyrocytes of FRTL-5 cells. Although ERp29 mRNA was constantly expressed, its expression began to increase remarkably from 10-9 M TSH. and its maximum expression was at 5×10-9 M TSH (about 3.5 fold). On the other hand, the effect of TSH on the abundance of ERp29 mRNA started within 6 h, and peaked at 8 h (about 2.5 fold). Actinomycin D (transcription inhibitor) strongly blocked this effect while cycloheximide (translation inhibitor) did not. The half-life of ERp29 mRNA was about 4.5 h in the presence or absence of TSH that was not affected by the stability of ERp29 mRNA. The effect of TSH on the ERp29 gene expression was specific, while other growth factors (transfferin, insulin, and hydrocortisone) did not alter its expression. Our data indicate for the first time that the expression of ERp29 is regulated transcriptionally by TSH in the thyrocytes.

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Experimental Determination of Complex Moduli and Internal Damping of Laminated Composites (적층 복합재료의 내부감쇠와 복소탄성계수 측정에 관한 연구)

  • Lee, Jae-Hyeok;Park, Se-Man;Kim, Hyeong-Sam
    • Korean Journal of Materials Research
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    • v.8 no.10
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    • pp.905-911
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    • 1998
  • Damping is a property for materials and systems to dissipate energy during periodic deformations. Generally, damping causes stiff decrease in amplitudes and shifts in phases. Also, even at resonance, amplitudes are substantially attenuated. This phenomenon of damping helps in reducing stresses developed during vibrations and consequently improves fatigue lives of materials. In this work internal damping and complex moduli are experimentally determined. An impulse technique is utilized in experiments and cantilever beams are selected as test subjects for the measurements of flextural vibrations since the beams lend themselves easily as simplistic ideal models. A resonance method is employed to determine resonance frequencies which are utilized to compute storage moduli. Also, loss moduli are evaluated from damping capacities and storage moduli. The storage and loss moduli combined yield complex moduli. Finally internal damping is evaluated from bandwidth technique, the real component of the transfer function.

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Evaluation of Stability of Quay Wall Considering Overtopping of Tsunami (지진해일파의 월파를 고려한 해안안벽의 안정성평가)

  • Lee, Kwang-Ho;Kim, Do-Sam;Kim, Tae-Hyung
    • Journal of the Korean Geotechnical Society
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    • v.28 no.9
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    • pp.31-45
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    • 2012
  • This study was conducted to estimate the stability of a quay wall in case of wave overtopping under the combined action of an earthquake and tsunami using limit equilibrium method. The tsunami force was calculated by using a numerical program called TWOPM-3D (3-D one-field Model for immiscible TWO-Phase flows). Especially, the wave force acting behind the quay wall after a tsunami wave overtopping was estimated by treating back fill as a permeable material. The stability of the quay wall was assessed for both the sliding and overturning modes under passive and active conditions. The variation in the stability of the quay wall with time was determined by parametric studies, including those for the tsunami wave height, seismic acceleration coefficient, internal friction angle of the soil, wall friction angle, and pore water pressure ratio. When the earthquake and tsunami were considered simultaneously, the tsunami induced wave overtopping increased the stability of the quay wall under the passive condition, but in the active condition, the safety factors decreased.

Factors Related to Smoking Behavior among High School Students (일 지역 고등학생의 흡연경험 관련 요인)

  • Choi, Won-Hee;Je, Mi-Soon;Lee, Sam-Soon
    • Journal of Korean Public Health Nursing
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    • v.24 no.2
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    • pp.226-236
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    • 2010
  • Purpose: The study investigated factors related to the smoking behavior among 639 high school students in Geoje, Korea. Methods: Data collected by self-reported questionnaires was analyzed by the SPSS WIN 14.0 program with Chi-test, t-test, and multiple logistic regression analysis. Results: Smoking behavior differed by gender (p=.002), school type (p=.001), experience with alcohol consumption (p=.005), family harmony (p=.003), father's smoking (p=.001), academic achievement (p=.010), self-esteem (p=.010), stress (p=.004), and attitude to smoking (p=.0001). Smoking behavior was significantly associated with gender (odds ratio (OR)=0.66, 95% confidence interval (CI)=0.46-0.95), school type (OR=1.52, 95% CI=1.03-2.23), experience with alcohol consumption (OR=0.56, 95%CI= 0.39-0.82), academic achievement (OR=1.98, 95-I=1.20-3.29), attitude to smoking (OR= 0.76, 95%CI=0.69-0.84) and father's smoking (OR=1.59, 95%CI=1.11-2.29). Conclusion: Anti-smoking programs for high school students should especially consider those at higher risk (males in vocational high school with no drinking experience of drinking, lower academic achievement, favorable attitude to smoking, and whose fathers smoke). Community efforts to reduce adult smoking would be advantageous.

Development of Construction Project Control System for Large Sized Construction by Process and Data Modeling (대형건설공사의 프로세스 및 데이터 모델링을 통한 건설프로젝트관리체계 구축에 관한 연구)

  • Choi Yoon-Ki;Lee Hyun-Soo;Hwang Young-Sam;Kim Young-Suk;Kim Woo-Young;Song Young-Woong
    • Korean Journal of Construction Engineering and Management
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    • v.5 no.2 s.18
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    • pp.153-161
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    • 2004
  • The systematic material and labor management planning should be established on accomplished EVM data. The matrix method of integrated cost and schedule was used with common category concept according to the construction project control system. The construction project control system was suggested through analyzing process and data modeling based on integrated cost, schedule and material. Information of construction project can be developed the relationship between the field data and the integrated cost, schedule database. Process and data modelling is provide a standard data format which are related to the material, labor management based on integrated cost, schedule database.

Seasonal Variation of Pollutant load flowing into Yeong-Il bay (영일만 유입오염부하량의 계절 변동에 관한 연구)

  • Yoon, Han-Sam;Lee, In-Cheol;Ryu, Cheong-Ro;Park, Jong-Hwa
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2002.10a
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    • pp.100-107
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    • 2002
  • This study investigates the seasonal variation and spatial distribution characteristics of pollutant load, as executing the quantity valuation of pollutant load inflowing into Yeong-Il bay from on-land including the Hyeong-san river. Annual total pollutant generating rate from Yeong-Il bay region are 202ton to BOD, 620ton to SS, 42ton to T-N, 16ton to T-P respectively, if expressly point out, pollutant generating rate from the Hyeong-san river is the greatest, which BOD ratio is 78.2%, SS 88.5%, T-N 62.5%, T-P 73.1%. As calculating Tank model with input value of daily precipitation and evaporation of 2001 year in drainage basin of the Hyeong-san river, Estimated result of the annual total river discharge effluencing from this river is $830{\times}106m^3$. As result to estimating annual total effluence rate outflowing at the rivers from each drainage basins, annual total inflow pollutant rate are BOD 10,633ton, SS 19,302ton, T-N 15,369ton, T-P 305ton. The III basin which is population congestion region of the Pohang-city drain away a good many pollutant load than the V basin including the Neang-Chun with wide drainage area. Especially, a great many T-N than T-P inflow into Yeong-Il bay. The accumulation of pollutant load effluenced from on-land will happen on at the inner coast region of Yeong-Il bay, finally we would make a prediction that the water quality will take a bad turn.

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Numerical Simulation of water quality by ${\Delta}COD$ method for Inner Productivity Estimation of Yeong-Il Bay (간이변환 수질예측모델에 의한 영일만 내부생산성 평가)

  • Yoon, Han-Sam;Ryu, Cheong-Ro;Lee, In-Cheol;Kim, Heon-Tae
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2003.05a
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    • pp.99-104
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    • 2003
  • This study investigated the yearly variation of pollutant loads outflowing from six watershed of Yeong-il Bay and compared the relationship of pollutant load and water quality, and estimated the Inner productivity of Yeong-Il Bay by using ${\Delta}COD$ method which analysis nonlinear process of water quality. As the estimated results for the pollutant loads of Yeong-Il Bay, total COD load outflowing from Hyeong-san river in flood season(summer) of 2001 year was 2275.0 kg/hr and in dry(low water) season(winter) 852.8 kg/hr, respectively. Load quantity in flood season was about 2.67 times than that in dry season. And as the calculated results of the net-flux of water for seven divisions, it showed that the net-flux of water increased for the divisions of the north coast and inner sea of Yeong-Il Bay but decreased for the south coast. On the contrary, for the cases which water quantity increase from land, the net-flux of water in estuary front of Hyeong-san river decreased but outflowing quantity of that though division of the south coast of Homi-got increased. Finally, this study compared the Inner productions for flood and dry season of Yeong-il Bay by using ${\Delta}COD$ method.

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Study of the Optimal Mesh Size for a Safety Net for Preventing Falls from Wave-dissipating Blocks (소파블록 낙상사고 방지를 위한 안전망 그물코 크기 산정에 관한 연구)

  • Yoon, Han-Sam;Kim, Min-Su;Jang, Sung-Chul;Lee, Hieung-Sin
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.25 no.7
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    • pp.834-840
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    • 2019
  • Recently, due to increased tourism and leisure activities, falls by fishers from coastal wave-dissipating blocks (breakwaters) in Korea have been rising. We investigated the optimal mesh size for use in safety nets designed to cover Tetrapod (TTP) breakwaters to prevent casualties from falls. This is a prerequisite for considering the scale and economics of safety net facilities. The optimal mesh size was determined based on the fisher gender and age, and the bodily features of Koreans. The optimal mesh size was found to be 18.6-27.0 cm, derived based on the femoral length and chest circumference.

Analysis of Pollutant Loads and Physical Oceanographic Status at the Developing Region of Deep Sea Water in the East Sea (동해 심층수 개발해역의 오염부하량 해석과 해동변동)

  • LEE IN-CHEOL;YOON BAN-SAM
    • Journal of Ocean Engineering and Technology
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    • v.19 no.1 s.62
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    • pp.14-19
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    • 2005
  • As a basic study for establishing the input conditions of a forecasting/estimating model, used for deep-sea water drainage to the ocean, this study was carried out as follows: 1) estimating the amount of river discharge and pollutant loads into the developing region of deep sea water in the East Sea, Korea, 2) a field observation of tidal current, vertical water temperature, and salinity distribution, 3) 3-D numerical experiment of tidal current to analyze the physical oceanographic status. The amount of river discharge flowing into this study area was estimated at about $462.7{\times}103 m\^3/day$ of daily mean in 2002. Annual mean pollutant load of COD, TN, and TP were estimated at 7.02 ton-COD/day, 4.06 ton-TN/day, and 0.39 ton/day, respectively. Field observation of tidal current normally shows 20-40cm/sec of current velocity at the surface layer, and it decreases under 20cm/sec as the water depth increases. We also found a stratification condition at around 30m water depth in the observation area. The differences in water temperature and salinity, between the surface layer and the bottom layer, were about 18 C and 0.8 psu, respectively. On the other hand, we found a definite trend of 34 psu salinity water mass in the deep sea region.

Survey study on planning direction of integrated model for the disabled and the elder - Focusing on the case of foreign country - (장애인 및 노약자의 생활시설 통합모델 설정을 위한 조사연구 - 해외 시범사업 사례를 중심으로 -)

  • Kang, Byoung-Keun;Seong, Ki-Chang;Park, Kwang-Jae;Yun, Young-Sam;Kim, Sang-Woon;Lee, Joo-Hyung
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.15 no.2
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    • pp.23-30
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    • 2009
  • The purpose of this study is to suggest planning directions of architectural integrates model by analysing the foreign case of integrated services for the aged and the disabled. For this study, we have researched on three different aspects. Three aspects are the element of barrier-free, architectural planning, information technology and operation. Based on the analysis of overseas examples, the good circumstance for both the disabled and the elder as one of member in the local societies could be defined like the following conditions: that is, (1) IT technology facilitates both barrier-free architecture and life to be easier and safer, and (2) both the disabled and the elder in local societies live together with the non-disabled in the same community. To realize this purpose, for a short-term plan, the system of feedback, examining the results of the research through the examples of housing plan, should be improved. In addition to, the system of public service, such as introducing the institutes for social educations, should be developed to result in the change of social insight. For a long-term plan, the whole society should have the research and plan of the unified model in a dimension of cities, where the network of public welfare is deeply associated with the system of the architecture, traffic, streets, and living-supporting information.

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