• 대한간호학회지
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• 제22권1호
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• pp.81-115
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• 1992

The problem addressed by this study was to determine the effect of nurse - patient agreement on the means to achieve nursing goals in the early postpartum period of primiparous mothers. It was hypothesized that the experimental treatment would result in hegher self-confidence and satisfaction in maternal role performance. This purpose was to contribute to the planning of nursing care to enhance self- confidence and satisfaction in maternal role performance and to the development of relevant nursing theory. Especially, the early postpartum period is crucial toward in recovery from childbirth and attainment of the maternal role. Maternal role attaintment is a complex social and cognitive process of stimulus -response accomplished by learning. Most women attain the maternal role sucessfully. But, some primiparous mothers experience difficultites in attainment of the maternal role due to lack of experience and knowledge. Self-confidence and satisfaction in maternal role performance are important factors in attainment and adjustment to the maternal role (Mercer, 1981a, 1981b ; Lederman, Weigarten, and Lederman, 1981 :Bobak and Jensen, 1985). Nursing is defined as behaviors of nurses add patients that attain nursing goals through action, reaction, interaction, and transaction. For attainment of nursing goals, active participating transactions must occur by agreement on the means to achieve those goals through nurse -patient mutual goal setting and establishment of their active relationships(King, 1981, Ha, 1977). Based on King's theory of goal attainment (1981), this stuy was planned as a non-equivalent control group, non -synchronized quasi -experimental design using agreement on the means to achieve nursing goals in early postpartum as the experimental treatment. The data were collected from July 20 to Sep. 1, 1991 by questionnaires with 60 primiparous mothers planing to breast feed after normal deliveries at W hospital in Pusan, Korea. The subjects were divided into a control group(conventional group) -those admitted from July 20 to Aug. 12, and an experimental group(agreement group) - those admitted from Aug. 13 to Sep. 1. The instument for agreement on the means to nursing goals in the early postpartum period included five steps - identification of disturbances of problems through action, reaction, and interaction with primiparous mothers : mutual early postpartal nursing goal setting : exploration of the means to achieve goals ; agreement on the means (self- care, ealry maternal -infant contact, performance of mothering behavior, and communicating about the infant's behavior and health condition) : implementation of the means. This instrument was developed on the basis of King's elements that lead to transactions in nurse-patient interactions. Lederman et al's (1981) scale for Confidence in ability to cope with tasks of motherhood and Lederman et al's(1981) scale for Mother's satisfaction with motherhood and infant care were used to measure self-confidence and satisfaction in maternal role performance ·with the subjects immediately after admission and on the day of discharge. Self-care performance in the experimental group was measured by self -evaluation tool developed by the investigator from the literature concerned. The tools to measure Pelf-confidence and satisfaction in maternal role performance, and the tool to measure self-evaluation of self-care performance were tested for internal reliability. Cronbach's Alphas were 0.94, 0.94, and 0.63. The data were analysed by using in S.P.S.S. computerized program and included percentage, x²-test, t-test, ANOVA, and Pearson Correlation Coefficient. The conclusions obtained from this study are summerized as follows : 1. The degree of self-confidence in maternal role performance of the total subjects group measured before the experimental treatment was above average with a mean score of 2.77(range 2.14-3.64). Out of 14 items, those with relatively high mean scores were ‘I would like to be a better mother than I am’(3.95), and ‘I have my doubts about whether I am a good mother’(2.87). Those with low mean scores were ‘I know that my baby wants most of the times’(2.28), ‘When the baby cries, I can tell what she /he wants’(2.37), and ‘I have confidence in my ability to care for the baby’(2;50). That is, the self - confidence of Primiparous mothers was considerably high in mothering, but rather low in activities concerning the infant care and understanding of the infant behavior. The degree of satisfaction in maternal role performance of the total subjects group measured before the experimental treatment was high with a mean score of 3.18(range 1.92-3.92). Out of 13 items, those with relatively high mean scores were ‘I am glad 1 had this baby now’(3.75), ‘I play with the baby between feedings when s/he is awake and quiet’(3.67), and ‘I enjoy being a mother’(3.27). Those with low mean scores were ‘I am upset about having too many responsibilities as a mother’(2.78), ‘It bothers me to get up for the baby at night’(2.82), and ‘I get annoyed if the baby frequently interrupts my activities’.(2.82), That is, the satisfaction of primiparous mothers was considerably high in mothering and infant care, but rather low in restraints in time or on the mother's self accomplishment and development. 2. Agreement on the means to achieve nursing goals in the early postpartum period included process of mutual goal setting, exploration of the means to achieve goals, and ahreement in concert means to achieve goals based on the mothers' condition, concerns, self-perception of the nurse - patient interactions. In the process of agreement, there was agreement that the means to achieve goals should be through trust and establishment of active relationships with the nurse through identification of problems according to planned nursing goals and active interaction, such as explanations, teaching, changing of opinions, acceptance or rejection of explanations, and proposing of questions. Therefore agreement on the means to achieve nursing goals in the early postpartum period appears to be an effective nursing intervention for primiparous mothers. 3. The degree of self- confidence in maternal role performance of the exprimental group was higher than that of the control group(t＝3.95, p＜0.01). Out of 14 items, those with higher score in the experimental group were ‘I would like to be a better mother than I am’(t＝1.93, p＜0.05), ‘I know that my baby wants most of the times’(t＝2.75, p＜0.01), ‘When the baby cries, 1 can tell what she/he wants’(t＝2.10, p＜0.05), ‘I have confidence in my ability to care for the baby’(t＝3.72, p＜0.01), ‘I trust my own judement in deciding how to care for the baby’(t＝1.96, p＜0.05), ‘I feel that I know my baby and what to do for him /her’(t＝2.44, p＜0.01), ‘I am concerned about being able to meet the baby's needs’(t＝2.87, p＜0.01), ‘I know what my baby likes and dislikes’(t＝3.26, p＜0.01), ‘I don't know to care for the baby as well as I should’(t＝2.07, p＜0.05), and ‘I am unsure about whether I give enough attention to the baby’(t＝3.04, p＜0.01), That is, the degree of self-confidence in mothering, activities concerning infant care, and understanding of infant behavior of the experimental group was higher than that of the control group. Therefore, the first hypothesis, that the degree of self-confidence in maternal role performance of the experimental group would be higher than that of the control group, was supported(t＝3.95, p＜0.01). 4. The degree of satisfaction in the maternal role performance of the exprimental group was higer than that or the control group(t＝2.31, p＜0.05). Out of 13 items, those with higher score in the experimental group were ‘I am glad I had this baby now’(t＝2.29, p＜0.05), ‘I enjoy taking care of the baby’(t＝2.4g, p＜0.01), ‘It is boring for me to care for the baby and do the same thing over and over’(t＝2.87, P＜0.01), ‘I am unhappy with the amount of time I have for activities other than childcare’(t＝2.51, p＜0.01), and ‘When bathing and diapering the baby, I would like to be doing something else’(t＝2.43, p＜0.01). That is, the degree of satisfaction in mothering, infant care, and restraints in time of on the mother's self accomplishment and development in the experimental group was higher than that of the control group. Therefore, the second hypothesis, that the degree of satisfaction in maternal role performance of the experimental group would be higher than that of the control group, was supported(t＝2.31, p＜0.05). 5. The third hypothesis, that the higher the degree of satisfaction in materenal role performance, the higher the degree of self-confidence in materenal role performance in the experimental group, was supported (r＝0.57, p＜0.01)

• 한국가정과교육학회지
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• 제16권2호
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• pp.13-26
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• 2004

이 연구는 가정과교육에서 인성교육을 체계화시켜 강화할 수 있는 방안을 마련하기 위하여, 제7차 기술ㆍ가정교육과정의 가정과교육 영역에서 “인성교육의 목표와 내용”을 분석, 제시하되, 가정과 수업상황에서 효율적으로 활용할 수 있는 교수ㆍ학습 활동을 함께 개발하여 제시하고자 하였다. 그 결과, 제7차 기술ㆍ가정 교육과정의 가정과교육 영역의 모든 영역에서 인성교육이 구현될 수 있는 결과가 도출되었다. 특히 가정과교육에서는, 첫째, 평등 및 인권존중의 가치와 관련한, 평등 가족 형성을 위한 인성교육, 둘째, 환경보호와 관련한 다양한 가치를 인식하고 실천할 수 있는 인성교육, 셋째, 길리건(Gilligan)등의 주장하는 보살핌의 윤리에 관련된 덕목들-즉, 자선, 자비, 용서, 우애, 사랑, 희생, 양보, 대화, 타협 등의 가치들에 대한 인성교육을 실천할 수 있는 것으로 나타났다. 특히 이러한 보살핌의 가치들은 과거 전통적인 가정과 교육에서 비판되어 온 가족 이기주의적 보살핌의 가치를 벗어나 타인과 이웃, 공동체에 대한 보살핌의 윤리로 확대되고 있다. 한편, 다른 교과와는 차별적으로 가정과교육에서 수행되는 인성교육은, 이상에서 논의한 다양한 가치들을 가족원들과의 일상적인 매일의 생활에서 펼쳐지는 다양한 실제적인 역할 수행관계를 통하여 습득시킴으로써, 단순한 앎의 지식이나 감정으로서 머무는 것이 아닌 경험을 통한 실천적 행위로 발전시킬 수 있는 특성을 가진다. 이러한 특성은 도덕적 행위의 목표도달에 가정과교육이 매우 유효한 역할을 할 수 있는 교과임을 입증해 주는 결과이다. 이 연구의 결과는 학교교육에서 가정과교육이 타 교과와는 구별된 목표와 내용, 방법을 통해 인성교육을 효과적으로 수행할 수 있는 교과임을 입증해 주고 있는데, 이는 가정과교육이 학교교육에서 필수교과로서 자리매김 되는 중요한 당위성을 제공해준다. 추후연구는 가정과 교육 영역에서 수행될 수 있는 특성 있고 실천적인 인성함양프로그램(교수-학습 활동안)이 개발되어야 하고, 이러한 프로그램에 대한 실증적 자료가 축적되는 경험적 연구가 수행되어야 할 것이다.

• 지능정보연구
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• 제20권4호
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• pp.155-169
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• 2014

다양한 빅데이터 기술이 발전함에 따라, 기업의 전략결정에 있어서 과거에는 의사결정자의 직관이나 경험에 의존하는 경향이 있었다면, 현재는 데이터를 활용한 과학적이고 분석적인 접근이 이루어지고 있다. 이에 많은 기업들이 경영정보시스템 중의 하나인 비즈니스 인텔리전스 (Business Intelligence) 시스템의 예측분석 기능을 활용하고 있다. 하지만, 이러한 시스템이 미래의 경영환경 변화를 예측하고 기업의 의사결정을 돕는 조언자 (Advisor)로서 역할을 한다고 가정할 때, 시스템에서 제공하는 분석결과가 의사결정자에게 도움을 주는 조언 (Advice) 의 역할을 하지 못하는 경우가 많은 실정이다. 따라서, 본 연구에서는 미래예측의 문제에 있어 의사결정자가 시스템의 조언을 따르는데 영향을 미치는 요소들과 영향력에 대해 분석하고, 그 결과를 바탕으로 데이터 기반의 의사결정을 보다 적극적으로 지원하는 시스템 환경을 제시하고자 한다. 좀 더 구체적으로는 예측 과정에 대한 자세한 설명이나 근거 제시가 시스템의 예측결과에 대한 의사결정자의 수용정도에 미치는 영향을 연구하였다. 이를 위하여 193명의 실험자를 대상으로 영화의 개봉 주 매출액을 예측하는 업무를 수행하고, 예측에 대한 설명의 길이와 조언자의 유형(사람과 시스템의 조언 비교)뿐 아니라 의사결정자의 개인 특성이 의사결정자의 조언 수용정도에 미치는 영향을 분석하였다. 시스템에서 제공하는 조언 내용인 예측결과와 설명에 대해 의사결정가가 느끼는 유용성, 신뢰성, 만족도가 조언의 수용에 미치는 영향도 분석하였다. 본 연구는 시스템의 분석결과를 조언으로 보고 조언자와 조언에 관한 의사결정학 분야의 선행연구를 접목시켜 경영정보시스템 연구 분야를 확장하였다는 점에서 연구의 의의가 있고, 실무적으로도 데이터 기반의 의사결정을 보다 적극적으로 지원할 수 있는 시스템 환경을 만들기 위해서 고려해야 할 점들을 제시함으로써 시스템 활용을 위한 정책결정에도 도움을 줄 수 있을 것으로 본다.

• 가정과삶의질연구
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• 제2권1호
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• pp.131-150
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• 1984

The purpose of this study is to explore the family as an interaction system, concentrating on the mutual influences between communication and family development; (1) how Communication patterns affect family relationships, and (2) how relationships among family members affect communication. In order to do this Galvin, Brommel used the following frame work; family is a system in which communication regulates cohesion and adaptability by a flow of message patterns through a defined network of evolving interdependent relationships. A family system consists of members, the relationships among them, the family attributes, the members attributes and an environment in which family functions. Within the framework of common cultural communication patterns, each family has the capacity to develop its own communication code based on the experiences of individual members and the collective family experience. Most of us develop our communication skills within the family context learning both the general cultural language and the specific familial communication code. Communication may be viewed as a symbolic, transactional process as the process of creating and sharing meanings. To say that communication is a process implies a continuous interaction of an indefinite large numbers of variables with a concomitant,. continuous change in the values taken by these variables. Finally the process implies change, Family functions include the primary functions of cohesion and adaptability, and supporting functions of family images, themes, boundaries, and biosocial issues. The primary functions reveal concepts integrated family interaction and supporting function, along with those of cohesion and adaptability, give shape to family life. the characteristics of developed relationships of richness, uniqueness efficiency, substitutability, pacing , openness spontaneity, and evaluation are reflected in the verbal and nonverbal behaviors with which family members negotiated a set of common meanings and develop thier own unique message system. The message system is the major element of communication process and influences both the form and the content of thier relationship and in create and share meanings. Family systems need to provide order and predictability for thier members, specifically focusing on communication rules and the networks by which messages are transmitted. Most rules emerge as a result of multiful interactions. There are basic rules and rules about rules, or metarules. Perceiving the rules of family system is very difficult because often family members don't think about the basic rules, much less the metarules. Breaking the rule may result in the creation of a new set because the system may recalibrate itself to accept more variety of behavior. Families develop communication networks to deal with the general issue. Family adaptability may be seen through the degree of flexibility in forming and reforming networks and networks become a vital part of the decision- making process and relate to the power dynamics operating within the family. Networks also play an integral part in maintaining the roles and rules operating with the family system. Thus networks and rules have mutual influence. The family -of -origin issues influence all aspects of family communication and account for many of the communication patterns, rules and networks and the role of the family -of-origin influences as a primary force for communication on behavior of newly forming systems. Each family system develops its own communication meanings. There is not one right way to communicate within a family but may be indefinitly large change of family life and communication behavior. Study on functional family communication helps to gain a better understanding of dynamics of family communication and ability of a new insight into the family.

• 한국문헌정보학회지
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• 제11권
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• pp.147-183
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• 1984

This is an analytical study on Munheongak (文獻閣) and it's catalogue. The major objective of the study is to get a recognition of Munheongak under the culture of Sukjong (肅宗) period in Korean library history. Most of early studies made on such a category have been concentrated on Jiphyunjeon (集賢殿), Hongmungwan (弘文館), Kyujanggak(奎章閣) and their backgrounds. In this study, the author has invest gated Kungwolji (宮闕志), Munheongakseomg (文獻閣書目) and other materials related to this subject. The findings of the study can be summarized as follows: 1. Munheongak was established by king Sukjong in the 26th year of his reign. According to some records of Kungkwolji, the reason of establishment of the library was to arrange the collection in the Sango (相庫) consisted of various kinds of materials. In case of books, most of them turned out to be Korean books. 2. Munheongak was sited to the estern side of Kyunghyundang (景賢堂), which was located on the Kyungdeokgung (慶德宮). After Youngjo (英祖) the place was called Kyungheuigung (慶熙宮) so as to avoid the name of the precedent king. But these days, both the buildings are not to be found. 3. After its establishment, the library could not play the role as a library because of the then political situation and sectionalism. During the period of the revival of the learning from Youngjo till Jeongjo(正祖) the function of the library was in a stagnant state. Kyujanggak played the part in its place. 4. Referring to the collection management, the Munheongakseomog is equipped with 101 titles, 2,525 volumes, which are arranged by means of the traditional Chinese classification system. 5. The classification scheme is based on the traditional Chinese classification system which might divide all subjects into four categories such as: Confucian classics division, Historical documents division, Master's division, and Collection of literature division. Some illustrations reveal that the classification system was directly influenced by Seogoseomg (書庫書目) : the influence reflected in the classes for the translated literature and writings, poems, genealogy about kings, etc. But some subdivisions such as a class of Annals, Historical Epcerpts were omitted in the classification scheme, which did not strike the balance in the system in terms of the present theory of classification. Most of bibliographical descriptions were also influenced by Seogoseomog but some elements were partly omitted. 6. The special feature of the collection building is the absence of books in Collection of literature division except only three kinds of books in examining the Munheongakseomog. Since this is rather a comprehensive study for such aspects as historical backround, catalogue, and cultural environment of Munheongak and its related record, it is advised that further and additional research should be made.

• 한국식생활문화학회지
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• 제23권1호
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• pp.130-137
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• 2008

If we may practice the nutrition education planned on the basis which carefully grasped the inappropriate behavioral determinants of middle-school students, it might be an effective method achieving the change in perception and behavior improving the distorted perception about the ideal body shape, so we are to suggest the 8 week program of body shape perception improvement for successful nutrition education as follows. The body shape perception improvement program is a step-by-step group consulting program. At the introduction stage, we let them understand the meaning of true beauty and body change of teenage period and forming of sexual identity. At the stage of perception conversion, we let them have the opportunity to observe the status of body perception of the teenager and self-observation. At the stage of correction, we let them criticize the distorted body image in the society with mass media at the same time with the self-reflection. At the stage of maintenance and evaluation, we suggested the behavior guidance while preparing it. Setting this as the basis, we applied the contents such as the evaluations through cultural sharing events making somethings while directly participating. As the target groups to practice education were middle school students, we considered the learning level and behavioral features of the middle school students, and composed the programs including the methods such as role play, watching real things, media production, discussions and experiences. If the program of body shape perception improvement developed at this study could be utilized at the field of schools, the teenagers can change their ways of thought naturally avoiding the view about unified appearance rightly perceiving negative self-image that the teenagers can have and if the group consulting can be practiced regularly at each school, many students may experience the change in perception, so it might solicit the improvement of health of the families and local societies as well as that of the individual student.

• 한국의사학회지
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• 제24권2호
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• pp.25-55
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• 2011

The currently existing "Bonchojeonghwa (本草精華)" is a manuscript without the preface and the epilogue, composed of 2 books in 2 volumes. This book is a quintessence of knowledge on science of medicinal ingredients (medicinal phytology I herbal science) as well as an trial of new development in Chosun medical science. I.e. this book includes surprising change representing medical science in Chosun dynasty as a single publication on science of medicinal ingredients. It holds a value essential to clinician as a specialized book in medicinal ingredients, and Includes richer content on medicinal ingredients than any other books published before. In addition, it is away from boring list-up of superfluous knowledge as seen in "Bonchokangmok(本草綱目)" published in China, and well summarizes essential knowledge which can be used within a range of medicines available in Korea. This book has an outstanding structure that can be even used in today's textbook on science of medicinal ingredients, as it has clear theory, system and classification. Because it handles essential learning points prior to prescription to disease, it is possible to configure new prescription and adjustment of medicinal materials. Moreover, this book can play a good role for linguistic study at the time of publication, because it describes many drugs in Hangul in many parts of the book. "Bonchojeonghwa" includes a variety of animals, plants and mineral resources in Korea, like "Bonchokangmok" which was recently listed in UNESCO. As such, it has a significance in natural history as well as pharmacy in Korean Medicine. It has various academic relationships all in biologic & abiologic aspects. It has importance in sharing future biological resources, building up international potential, setting up the standard for biologic species under IMF system, and becoming a base for resource diplomacy. We should not only see it as a book on medicinal ingredients in terms of Oriental Medicine, but also make an prudent approach to it in terms of study strengthening Korea's national competitiveness. After bibliographical reviewing on the features & characteristics of the only existing copy of "Bonchojeonghwa" housed in Kyujanggak(奎章閣) of Seoul National University, the followings are noted. First, "Bonchojeonghwa" is a specialized book on medicinal ingredients voluntarily made by private hands to distribute knowledge on drugs in the desolate situation after Imjinoeran (Japanese Invasion in 1592), without waiting for governmental help. Second, it raised accessibility and practicality by new editing. Third, it classified 990 different kinds of drugs into plant, animal, and mineral at large, and dassified more in detail into 15 'Bu' and 48 'Ryu' at 258 pages. Fourth, the publication of this book is estimated to be around 1625~1633, at the time of Injo's reign in 17th century. Fifth, it contains the existing & up-to-date knowledge at the time of publication, and it is possible to see the supply-demand situation by Hangul descriptions in 149 places in the book. By the fact that there are many linguistic evidences of 17th century, explains well when the book was published.

• 한국과학교육학회지
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• 제35권4호
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• pp.691-707
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• 2015

이 연구는 생명과학교사들의 진화개념 향상을 위한 논변활동 프로그램을 개발하고 이를 교사교육에 적용하여 진화개념에 대한 논변활동 특성을 분석함으로써 효과를 알아보고자 하는 것이었다. 이를 위해 먼저 진화를 이해하는데 필요한 주요 개념들을 문헌 조사를 통해 추출하여 '변이', '변이의 유전', '경쟁', '자연선택과 적응', '차등적 생식력', '개체군 내 개체분포의 변화', '대진화'를 주요개념으로 선정하였고, 각각의 개념에 대한 논변활동 질문지를 개발하였다. ADI모형을 변형한 7단계로 이루어진 순환적 논변활동 학습모형도 개발하였다. 총 7회에 대학원 교과교육 수업에 적용하였다. 현직 생명과학교사 4명과 예비 생명과학교사 2명을 대상으로 남, 여 3명씩 두 개의 소집단으로 구성하여 논변활동을 진행하였다. 프로그램이 진행되는 동안 녹음을 통한 담화와 논변글쓰기의 자료를 수집하여 분석하였다. 논변글쓰기는 '설명의 충분성', '설명의 개념적 수준', '증거의 수준', '정당화의 적절성'의 4가지 범주를 기준으로 논변의 질 수준을 분석하여 사전사후에 진화개념의 변화 정도를 확인하였고, 담화분석을 통해 진화주요개념에 대한 논변활동 특성을 분석하였다. 논변글쓰기와 담화를 분석한 결과 개발된 논변활동 모형과 프로그램은 생명과학교사들의 진화개념 이해 향상에 효과적이었다. 이 연구는 논변활동을 통한 교수학습 전략이 생명과학교사교육을 위한 효과적인 진화개념학습 전략이될 수 있음을 보여주었다.

• 대한영양사협회학술지
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• 제11권2호
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• pp.205-215
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• 2005

Health is easily overlooked because it doesn’t be changed good or bad due to sudden effort or indifference unexpectedly but kept in daily life. Especially, schoolchildren period, an important lifetime to develop both physically and mentally needs to be helpful to promote the growth of the body and keep well-balanced mind through balanced and nourishing diet. The purpose of this study was to develop nutrition education contents for discretional activities in elementary school. The present educational contents about food and nutrition was analysed in the curriculum of elementary school. The results showed the Korean language(20.8%) included an highest ratio in educational contents about food and nutrition, the next was the courses of physical education and wise life(18.1%, each). As the educational contents about food and nutrition in the textbook were dealt with food information (20.8%), Health․Disease(15.3%), and correct dietary habits by order. We could found more contents in the text for the higher classes than for the lower classes. But the most of the contents appeared lack of structure, profundity and continuity for the systematic nutrition education in its entirety. The developed nutrition education contents for discretional activities in this study consist of korean dinning cultures and foreign dinning cultures, correct dinning etiquette, how to choose healthy food, personal sanitary and health, nutrients and food tower, and problem for children’s nutrition as main subject. This six main subjects were composed of 23 subtitles. The teaching manual consisted of the educational goal, background, teaching plan and effect-evaluation plan, and the notice point for the effective lesson. The teaching plan was made for 30 hours and consisted of cooking course, singing/making lyrics, games in nutrition, debate on dietary habit, and role play etc which are oriented to practical learning. We intended to develop this program that attempts to improve in dietary habit of schoolchildren. It is because once formed an adults dietary habit is difficult to change. Schoolchildren’s period is the best adjustable stage. Therefore, nutrition education in elementary stage can change to dietary habit and build the awareness of health.

• 생물정신의학
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• 제8권1호
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• pp.85-95
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• 2001

This study was designed to examine the effects of two antidepressant drugs on the expression of c-fos mRNA in cultured embryonic rat hippocampal neurons. The drugs used were imipramine and amitriptyline. On the fourth day of culture, hippocampal neurons were treated with variable concentrations of each drug. Competitive RT-PCR(Reverse Transcriptase-PCR) analysis was used to quantify the c-fos mRNA expression induced by each drug. Experimental results showed that acute and direct treatment with imipramine and amitriptyline with relatively low concentrations(imipramine ${\leq}10{\mu}M$, amitriptylne ${\leq}10{\mu}M$) had no inductive effect on the expression of c-fos mRNA in the rat hippocampal neurons. However, after treatment with relatively high concentrations(imipramine ${\geq}100{\mu}M$, amitriptyline ${\geq}100{\mu}M$) c-fos mRNA was not detected. These findings suggest the followings. Firstly, the action mechanisms of these drugs on the hippocampal neurons might not be mediated by c-fos but by other immediate-early genes(IEGs). Secondly, their actions may be mediated indirectly via other areas of the brain. Thirdly, the expression of c-fos might be inhibited by high concentrations of these drugs, or the high concentrations could induce cell death. Finally, though cell death remains to be confirmed, the inhibition of c-fos induction or cell death could play a role in the cognitive impairments known to be adverse effects of some antidepressants. This study is believed to be a first step toward understanding the mechanisms of learning and memory. Further studies are needed to investigate the expression of various IEGs and changes in the hippocampal neurons of rat resulting from chronic treatment with antidepressant drugs.