• 제목/요약/키워드: Late effect

검색결과 1,524건 처리시간 0.027초

갈색거저리(Tenebrio molitor L.)에 대한 키틴합성저해제의 활성평가법 (The Evaluating Metod of the Insecticidal Activity of Three Chitin Synthesis Inhibitors against the Yellow Mealworm, Tenebrio molitor Linnaeus)

  • 박노중;송철;김길하;조광연
    • 한국응용곤충학회지
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    • 제33권4호
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    • pp.281-285
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    • 1994
  • 키틴합성저해제인 diflubenzuron, triflumuron, chlorfluazuron을 갈색거처리와 유충과 번데기에 처리하여 효력검정법을 개발하였다. 유충에 대한 처리는 국소처리와 독먹이처리를 행하였고, 번데기에 대하요 용체침적처리와 미량주사처리를 행하였다. 유충에 대한 10$\mu\textrm{g}$ 국소처리와 번데기에 대한 100ppm 용체 침적처리 결과 세약제 모두 유충 및 번덱의 발육에 아무런 영향을 주지 않았다. 유충에 대한 독먹이 처리에 있어서의 {{{{ { LC}_{ 50} }}}}값은 diflubenzuron 11.3, triflumuron 42.7, chlorfluazuron 6.2ppm이었다. 번데기에 대한 미량주사처리에서는 diflubenzuron 0.053, triflumuron 0.230, chlorfluazuron 0.340 $\mu\textrm{g}$/pupa의 {{{{ { LC}_{ 50} }}}}값을 나타내었다.

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Co-administration of erythropoietin and iron complex improves late-phase liver regeneration

  • Kim, Ji-Yoon;Choi, Dongho;Kim, Joohwan;Kim, Young-Myeong;Lim, Hyunyoung;Sung, Jeong Min;Lee, Min Kyu;Choung, Yoo Jin;Chang, Ji Hee;Jeong, Mi Ae
    • BMB Reports
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    • 제53권3호
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    • pp.148-153
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    • 2020
  • Erythropoietin and iron have individually shown beneficial effects on early-phase liver regeneration following partial hepatectomy (PHx); however, there are limited data on the combined effect on late-phase liver regeneration after PHx. Here we examined combined effects of recombinant human erythropoietin (rhEPO, 3,000 IU/kg) and iron isomaltoside (IIM, 40 mg/kg) on late-phase liver regeneration following PHx and investigated the possible underlying mechanism. Rats administrated with rhEPO showed significantly higher liver mass restoration, interleukin-6 (IL-6, a hepatocyte mitogen) levels, and Ki-67-positive hepatocytes on day 7 after PHx than saline-treated controls. These beneficial effects were further enhanced on days 7 and 14 by co-treatment with IIM. This combination also significantly improved liver function indices, such as increased albumin production and decreased bilirubin levels, but did not alter serum levels of toxic parameters, such as aspartate transaminase and alanine transaminase. This study demonstrates that the combination of rhEPO and IIM synergistically improves late-phase liver regeneration and function after PHx, probably by promoting IL-6-mediated hepatocyte proliferation without adverse effects. Thus, this combination treatment can be a potential therapeutic strategy for patients undergoing resection for hepatic malignancies.

포장 및 적입 방법이 늦가을배추의 저온저장 중 품질에 미치는 영향 (Effect of Packaging and Loading Conditions on the Quality of Late Autumn Chinese Cabbage during Cold Storage)

  • 김병삼;남궁배;김민정
    • 한국식품저장유통학회지
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    • 제8권1호
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    • pp.23-29
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    • 2001
  • 늦가을배추의 저온저장중 선도연장을 위하여 포장방법과 적입방법 개선에 대한 연구가 행하여졌다. 전반적인 상품성을 보았을 때 늦가을 배추는 $0^{\circ}C$에 저온 저장한 경우 3개월까지 저장, 출하가 가능한 것으로 여겨졌다. 그러나 저장 비용과 상품성에 따른 출고가격 등을 고려할 때 늦가을 김장 배추는 저장용 배추로는 부적합한 것으로 여겨졌다. 포장용기간 저장성은 플라스틱콘테이너와 골판지박스가 기존 그물망에 비하여 우수하게 나타났다. MAP 저장시 포장내의 가스 조성은 처리구간에 큰 유의적인 타이를 나타내지는 않았는데 대체로 산소 농도는 13~18% 정도, 이산화탄소는 0.75~7.48% 범위를 나타내었다. 따라서 배추의 호흡을 완전히 억제하기에는 부족한 환경 조건이었으나 $0^{\circ}C$ 저온 조건과 포장내의 고습도 조건의 조성으로 기존 저장방법에 비하여선도 연장 효과가 얻어진 것으로 사료되었다.

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뇌종양의 방사선치료후 발생한 만성변화의 CT소견 (CT of Late Complication of Central Nervous System after Radiation Therapy of Brain Tumors)

  • 홍성언;조종희;안치열
    • Radiation Oncology Journal
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    • 제2권2호
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    • pp.287-297
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    • 1984
  • The normal intracranial structures are relatively resistant to therapeutic radiation, but may react adversely in a variety of ways, and the damage to nerve tissue may be slow in making its appearance, and once damage has occured the patient recovers slowly and incompletly. Therefore, it is important to consider the possibility of either recurrent tumor or late adverse effect in any patient who has had radiotherapy. The determination o( rnorphological/pathological correlation is very important to the therapeutic radiologist who uses CT scans to define a treatment volume, as well as to the clinician who wishes to explain the patient's clinical state in terms of regress, progression, persistence, or recurrence of tumor or radiation-induced edema or necrosis, The authors are obtained as following results ; 1. The field size(whole CNS, large, intermediate, small field) was variable according to the location and extension of tumor and histopathologic diagnosis, and the tatal tumor dose was 4,000 to 6,000 rads except one of recurred case of 9,100 rads. The duration of follow up CT scan was from 3 months to 5 year 10 months. 2, The histopathologic diagnosis of 9cases were glioblastoma multiforme(3 cases), pineal tumor (3), oligodendroglioma (1), cystic astrocytoma (1), pituitary adenoma (1) and their adverse effects after radiation therapy were brain atrophy (4 cases) , radiation necrosis(2), tumor recurrence with or without calcification (2), radiation·induced infarction (1). 3. The recurrent symptoms after radiation therapy of brain tumor were not always the results of regrowth of neoplasm, but may represent late change of irradiated brain. 4. It must be need that we always consider the accurate treatment planning and proper treatment method to reduce undesirable late adverse effects in treatment of brain tumors.

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전작물의 잔주가 사일리지용 옥수수의 생장과 수량에 미치는 영향 (effects of Previous Crop Residues on Growth and Yield of Corn for Silage)

  • 김원호;김동암
    • 한국초지조사료학회지
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    • 제16권4호
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    • pp.299-306
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    • 1996
  • This experiment was conducted from 1991 to 1993 at the forage experimental field, College of Agriculture and Life Sciences, SNU, Suweon to investigate the effects of previous crop residues on growth and yield of succeeding corn(2ea mays L.) and also to determine the best double cropping system necessary to maximize the total dry matter yield of winter forage crops plus corn for silage. In this experiment, treatments consisted of no crop as a control, late maturing Kodiak rye(Seca1e cereale L.), Bamapoli forage rape(Brassica napus Subsp. oleifera L.), G-sprinter oats(Avem sativa L.), Chief crimson clover(Trifolium incarnatum L.), Jackson Italian ryegrass(lo1ium rnultiJlorum L.), Vantage vetch(Vicia sativa L.) and early maturing Koolgrazer rye(Seca1e cereale L.). Corn leaf number and silking date were not significantly affected by previous crop residues, but the leaf number of corn following Italian ryegrass was reduced by 1.9 relative to no previous crop. The plant height and LA1 were significantly reduced during early development when corn followed Italian ryegrass and late maturing Kodiak rye (p<0.05). The dry matter and estimated TDN yields of corn were significantly reduced when corn followed Italian ryegrass and late maturing Kodiak rye. The yield reductions for corn following Italian ryegrass, late maturing Kodiak rye and early maturing Koolgrazer rye, relative to com when no previous crops were planted, were 34, 17 and 8%, respectively. Therefore, the reduction in corn growth and yield in this experiment could be explained by an allelopathic effect resulting from the Italian ryegrass and rye residues. The highest total dry matter yield of 30,509kg/ha was obtained from an early maturing rye-corn double cropping sequence in combination among the eight cropping systems.

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1990년대 중·후반을 전후한 북반구 여름철 열대-중위도 원격상관의 장기 변화 (Interdecadal Changes in the Boreal Summer Tropical-Extratropical Teleconnections Occurred Around Mid-to-late 1990s)

  • 이준이
    • 대기
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    • 제28권3호
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    • pp.325-336
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    • 2018
  • This study investigates robust features of interdecadal changes in the Northern hemisphere summer tropical-extratropical teleconnection occurred around the mid-to-late 1990s by analyzing four different reanalysis data for atmospheric circulation and temperature, two precipitation reconstructions, and two sea surface temperature (SST) data during the satellite observation era of 1980~2017. For the last 38 years, there has been a significant increasing trend in anticyclonic circulation at lower and upper troposphere and 2 m air temperature with wavenumber-5 Rossby wave structure in the Northern Hemisphere (NH) extratropics. The increase has been accompanied with the significant weakening and northward shift of jet stream over Eurasia and the North Pacific. It is further found that there has been a significant interdecadal shift occurred around the mid-to-late 1990s in the two distinct modes of tropical-extratropical teleconnection: Western Pacific-North America (WPNA) and circumglobal teleconnection (CGT) pattern. After mid-to-late 1990s, the WPNA has played more important role in modulating the extratropical atmospheric circulation and surface climate, which has been preferentially occurred during the El $Ni{\tilde{n}}o$-Southern Oscillation (ENSO) decaying or transition summer such as 1998, 2010 and 2016. During these summers, severe heat waves were occurred over many parts of the NH extratropics due to the combined effect of the increasing trend in the barotropic anticyclonic circulation and the significant WPNA across the NH. Although weakened, the CGT also contributed to some of hot summers over many parts of the NH extratropics such as 1999, 2000, 2008, 2011, and 2012 when weak to moderate La $Ni{\tilde{n}}o$ was persisted.

코미디언 김희갑, 구봉서, 서영춘의 웃음 의미작용 분석 : 1960년대 후반기 한국 코미디영화를 중심으로 (An Analysis of the Meaning of Laughter by Comedians Hee-Gap Kim, Bong-Seo Koo and Young-Chun Seo : focusing on Korean Comedy Movies in the late 1960s)

  • 서곡숙
    • 한국엔터테인먼트산업학회논문지
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    • 제15권8호
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    • pp.75-89
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    • 2021
  • 본고에서 코미디언 김희갑, 구봉서, 서영춘을 중심으로 1960년대 후반기 코미디영화에 나타나는 웃음의 의미작용을 분석한 결과는 다음과 같다. 첫째, 코미디언의 내러티브적 웃음은 기성세대/청년세대의 세대 갈등, 하층계급/상층계급의 계층 갈등, 남성/여성의 젠더 갈등과 현실의 좌절을 나타낸다. 둘째, 코미디언의 웃음 창출 기제는 보수적인 기성세대에 대한 조롱, 부도덕한 상층계급에 대한 폭로, 좌절하는 하층계급에 대한 희화화를 보여준다. 셋째, 코미디언 웃음의 실천적 양상은 전통/근대의 균열, 경제적 불평등의 간극, 금지된 욕망의 표출을 드러낸다. 그래서 코미디언 김희갑, 구봉서, 서영춘은 비공식문화의 폐쇄적 개방, 캐릭터/퍼포머의 충돌을 통해 내부/외부의 경계자와 낙관적 세계관이라는 웃음의 의미작용을 보여준다.

학령후기 아동의 내현적 자기애가 전위 공격성에 미치는 영향: 내면화된 수치심과 거부민감성의 매개효과 (The Influences of Covert Narcissism on Displaced Aggression in Late Childhood: The Mediating Effects of Internalized Shame and Rejection Sensitivity)

  • 임혜은;한세영
    • 아동학회지
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    • 제37권4호
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    • pp.129-143
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    • 2016
  • Objective: This study aimed to examine the mediating effects of internalized shame and rejection sensitivity in the relationship between covert narcissism and displaced aggression in late childhood. Methods: The participants included 1,060 children (grades 5 and 6; 547 boys and 513 girls) from four elementary schools located in Seoul, Gyeonggi-do, and Chungcheong-do. Results: The primary results of this study were as follows. First, child covert narcissism had a direct effect on displaced aggression; children who perceived higher levels of covert narcissism exhibited more displaced aggression. Second, child covert narcissism had an indirect effect on their displaced aggression through internalized shame and rejection sensitivity. Children who perceived higher levels of covert narcissism reported more internalized shame and rejection sensitivity, which led to more displaced aggression. Conclusion: The findings of this research indicate that individual and interpersonal psychological factors need to be considered to explain displaced child aggression. Further, it is important that we help children to gain positive relationships with family and peers. It will help them break away their negative self or others representation, especially their internalized shame and rejection sensitivity.

Clonidine의 굴근반사(屈筋反射) 억제작용(抑制作用) (Clonidine-induced Inhibition of the Flexion Reflex in the Cat)

  • 권상옥;고상돈;신홍기;김기순
    • The Korean Journal of Physiology
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    • 제21권1호
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    • pp.67-77
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    • 1987
  • Effect of intravenously injected clonidine on the flexion reflex was studied in 15 decerebrated and spinalized cats. The flexion reflex was elicited by electrical stimulation of the tibial nerve or the common peroneal nerve and it was recorded as single unit activity from filaments of the L6 or L7 ventral roots. In order to obtain the late flexion reflex discharges, $A{\delta}$ and C afferent fibers were stimulated with single or train electrical pulses respectively. The flexion reflex, especially the late component, was markedly inhibited after intravenous administration of clonidine. The clonidine-induced inhibition of the flexion reflex was compared before and after treatment of the animals respectively with yohimbine and naloxone. The inhibitory effect on the flexion reflex of clonidine was not altered by naloxone, a ${\mu}-opioid$ receptor blocker, whereas it was completely blocked by yohimbine, an ${\alpha}_2-adrenergic$ antagonist. These results indicate that clonidine inhibits the flexion reflex through excitation of ${\alpha}_2-adrenoceptors$ even at the spinal cord level.

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Effect of Temperature Associated with Early Growth Stimulus on Shortening of Heading Dates in Rice

  • Song, Moon-Tae;Lee, Jeom-Ho;Cho, Youn-Sang;Hwang, Hung-Goo
    • Plant Resources
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    • 제5권2호
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    • pp.155-160
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    • 2002
  • The heading date is known to be controlled by two kinds of genetic constituent, photosensitivity and basic vegetable phase. For the latter, the effect of temperature in early growth period is critical to determine the shortness of vegetative growth periods in plant's life. A phytotron experiment on 55 rice cultivars, consisting of two ecotypes of rices, indica and japonica, was conducted at high and low temperature treatments at early growth stage to investigate the possible role of plant growth stimulus by high temperature to associate with shortening of heading date. The high temperature during the early growth stage stimulated the rice growth as measured by plant height with much difference of the growth response between indica and japonica. The conclusive finding that these growth stimulus in early growth stage was highly correlated with the acceleration of heading is, more or less, correlated with the heading of the late growth stage although we could not conclude the genes for early plant growth stimulus by high temperature is the same genes as the genes for accelerating of heading in the late growth stage of plants.

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