• Journal of Pharmaceutical Investigation
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• 제5권3호
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• pp.36-42
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• 1975

Effects of hydrolysed Antler for prevention or therapeusis of cho1esteremia in rabbit was examined by oral administration of hydrolysed Antler to Rabbits with lanolin diet or to cholesteremia rabbits. Examination were made on the blood cholesterol value, urinary excretion of cholesterol ,cholesterol in various organs, and rabbits bred on lanolin diet were used as the control. From these experimental data, it was found that the best decholesterol action is seen in a intial added hydrolysed Antler diet.

• 대한소아치과학회지
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• 제51권2호
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• pp.140-148
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• 2024

This study aimed to enhance the physicochemical properties of sodium iodide-based root filling materials, particularly solubility. In earlier developmental stages, the iodoform-containing paste exhibited high antibacterial efficacy but failed to meet only the solubility requirement among the ISO 6876 criteria. Therefore, this study focused on enhancing the physicochemical properties of the paste under development, particularly centering on reducing its solubility. Four experimental groups were established, including three control group. The previously developed D30 paste was named the Oil 33 group, and the control group was named the Vitapex^® group. The Oil 50 group, in which the oil content was increased, and the Oil 45L group, in which lanolin was incorporated. The physical properties (solubility, pH, flowability, and film thickness) of the four pastes were evaluated according to the ISO 6876 standards. No significant differences were observed between the Oil 45L and Vitapex^® groups in any of the physical property evaluations. While the Oil 33 and Oil 50 groups met the ISO 6876 standards for flowability and film thickness, the Oil 45L group met all the physical properties. However, reducing the overall oil content may be necessary to enhance the antimicrobial properties. The result of the physicochemical experiments showed that the Oil 45L group with the newly formulated composition and incorporated lanolin exhibited low solubility meeting the ISO 6876 standard of ≤ 3%. We were able to develop a paste with more stable solubility than previous iodide-based root-filling materials. Therefore, the oil content must be further adjusted to improve its antimicrobial properties. If other physical properties also meet the ISO 6876 standards and demonstrate excellent results in cytotoxicity tests, this root filling material could potentially replace existing options.

• 대한화장품학회지
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• 제6권1호
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• pp.9-13
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• 1977

• 대한핵의학회지
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• 제26권2호
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• pp.257-264
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• 1992

Diagnostic approaches such as angiography, ultrasound, computed tomography and nuclear magnetic resonance have limitation for contributing to the early clinical diagnosis of atherosclerosis. Recently, $^{99m}Tc-labelled$ low density lipoprotein was developed to detect early atherosclerotic lesion by external imaging with gamma camera. To determine whether $^{99m}Tc-LDL$ scintigraphy can visualize the active atherosclerotic lesion, rabbits were injected with $^{99m}Tc-LDL$, 3 months after feeding dietary fat (lanolin) and we obtained following results. 1) Labelling efficiency of $^{99m}Tc-LDL$ was $79\sim88%$. 2) Biodistribution study of normal rabbits with $^{99m}Tc-LDL$ revealed the high activities in spleen, adrenal gland, liver, kidney which are major organs of high metabolic rate of LDL. 3) Three months after feeding lanolin, serum cholesterol was markedly increased from $74{\pm}17mg/dl$ to $979{\pm}153mg/dl$ and histologic study of aorta after sacrificing the rabbit demonstrated marked atherosclerotic changes. 4) Atherosclerotic lesion of abdominal aorta which was confirmed with histologic study could be demonstrated in $^{99m}Tc-LDL$ scintigraphy after feeding lanolin for 3 months. In conclusion, the results of this preliminary investigation suggest that it may be possible to image active atheromatous lesion with $^{99m}Tc-LDL$. It is anticipated that this promising agent may allow the in vivo monitoring of preclinical atherosclerotic lesions and may be useful to evaluate the metabolic pathway of LDL in humans.

• 대한기계학회논문집
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• 제17권5호
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• pp.1161-1171
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• 1993

본 연구에서는 모델실험을 통해 실제재료에 관한 정량적인 정보를 얻기 위하 여 모델재료인 플리스티신에 라놀린(lanolin), 레진(resin)등을 첨가하여 새로운 유 동특성을 갖는 혼합 플라스티신을 개발하고자 하였다. 개발된 모델재료와 기존의 플라스티신을 MTS(Material Testing System)을 이용하여 링 압축실험과 실린더 압축 실험으로 온도와 변형률속도 변화에 따라 재료에 혼합된 첨가제가 모델재료의 마찰 특성과 기계적 성질에 미치는 영향을 조사하고 비교 검토하고자 한다. 또한 실제 재료의 다양한 가공공정을 시뮬레이션하기 위한 모델재료의 상사실험에서 다이와 소재 의 분리가 비교적 용이한 윤활제로 실링 페이퍼(sealing paper), 바셀린(vaseline)을 바른 실링페이퍼, 파우다(talc powder)의 마찰특성에 대해서도 연구되었다.그리고 조사된 모델재료들이 연강인 0.15%C강의 고온 (900.deg. C∼1100.deg. C)에서의 온도변화에 따 른 상사재료로 사용될 수 있는지의 타당성을 검토하고자 한다.

• 한국산림과학회지
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• 제105권4호
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• pp.505-509
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• 2016

본 연구는 현재 수목관리 현장에서 사용 중인 상처도포제의 유효성을 확인하기 위해 실시하였다. 티오파네이트메틸 도포제(상표명: 톱신페스트)는 은행나무, 느티나무, 왕벚나무에서, 라놀린은 느티나무와 왕벚나무에서, 테부코나졸 도포제(상표명: 실바코)는 왕벚나무에서 각각 무처리구 대비 유의하게 높은 상처유합률을 나타냈다. 페트롤리움젤리(상표명: 바셀린)는 은행나무, 느티나무, 왕벚나무 등 소나무를 제외한 전 수종에서, 인체 무독성 접착제(상표명: 오공본드)는 느티나무에서 각각 무처리구보다 유의하게 낮은 상처유합률을 보였다. 특히 바셀린을 처리한 느티나무와 왕벚나무 상처부위에서는 형성층이 괴사되어 상처가 확대되는 피해가 발생하였다. 소나무는 수지 유출로 인해 상처도포제 처리효과가 나타나지 않았다.

• 공업화학
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• 제5권3호
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• pp.419-424
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• 1994

금속공작유에 의해 발생하는 기름얼룩에 대하여 6종의 유지화합물(rapeseed oil, oleic acid, methyl oleate, oleyl alcohol, lauryl amine, lanolin)에 따른 영향을 조사하였다. 시험방법으로는 MIL-C-22235A의 방법을 사용하였으며 base oil(spindle oil; 1.5wt%의 황함유)에 유지화합물 10wt%와 항산화제 0.5wt%를 첨가시켜 도유용 sample을 만들었다. 시험결과 항산화제 중 B. T가 B. H. T.와 T. C. P보다는 기름얼룩 억제에 효과적이었으며, 산가는 기름얼룩 방지에 나쁜 영향을 미쳤다. 유지화합물의 화학구조에 의해 예견되는 바와 같이 oleic acid는 철이온과 반응이 가능하므로 시편에 심하게 기름얼룩을 발생시켰다.

• 한국응용과학기술학회지
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• 제20권4호
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• pp.341-345
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• 2003

Organic acid salt of fatty polyamide (DDDT) and acrylate of fatty carbamide (DDTCA) were synthesized as a main component for the softener. O/W type non-ionic softener (NSC) was prepared by blending DDDT and DDTCA with beef tallow, lanolin anhydride. polyoxyethylene(7) stearyl ether, and polyoxyethylene(50) oleyl ether. After treatment of NSC to all cotton fabrics, the physical properties such as tear strength, crease recovery, and flexing abrasion resistance were measured. As a result of the measurement, NSC was proved to be durable non-ionic softener with good softness.

• 대한화장품학회지
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• 제22권2호
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• pp.99-114
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• 1996

The MLV liposomes have been developed in many drugs and cosmetics fields. The phospholipid base is made from ceramides, cholesterol, cholesteryl ester, lecithin, lanolin ester, and B-sitosterol, and surfactants are made by using (PEG)n-sitosterol(n=5) and K-cetyl phosphate. We made visicles stable by passing samples through Microfludizer and croated multilamellar vesicles to make MLV liposomes similar to the structure of men's skin. In order to make MLV liposomes, we created lipid membrane films which a mixure of phospholipid base and polyol group was reacted above Tc(95$^{\circ}C$) by gelation for 3 hours. As the optimum conditions of Microfluidizer, we figured out 700 bar for the passing pressure of samples, 4$0^{\circ}C$ for its temperature, and 3 times of frequency to pass through samples. Our MLV liposomes is stable on conditions of a low temperature(5$^{\circ}C$) and a high temperature(45$^{\circ}C$), which is not to be split in a large range. We produced our own moisturizing cream which has a good affinity to skin by means of this system.

• 한국응용과학기술학회지
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• 제15권1호
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• pp.17-23
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• 1998

To prepare a O/W type nonionic durable softner(ANSA), synthesized 1, 3-dihexadanoyl-2, 7-dioxy-6, 8-di(2-hexadecanoyloxyethyl)-1, 3, 6, 8-tetraazacyclodecane as the main component of softner, was blended with beef tallow, anhydrous lanolin, polyoxyethylene(20) oleyl ether, sorbitan sesquioleate, and polyoxyethylene(7) stearyl ether in various compositions. Emulsion stability of ANSA was good, and the mixed HLB value was 9.8. After the treatment of ANSA to all cotton fabrics, the physical properties such as tear strength, crease recovery, and flexing abrasion resistance were measured, respectively. As a result of the measurement, ANSA was proved to be durable softner with good softness.