• Title/Summary/Keyword: Lanolin

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Effect of Hydrolysed Antler on Plasma and Organ' Cholesterol in Rabbits (녹용(鹿茸)의 가수분해물(加水分解物)이 가토(家兎)코레스테롤치(値)에 미치는 영향(影響))

  • Park, Joo-Suk;Kim, Jae-Bak
    • Journal of Pharmaceutical Investigation
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    • v.5 no.3
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    • pp.36-42
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    • 1975
  • Effects of hydrolysed Antler for prevention or therapeusis of cho1esteremia in rabbit was examined by oral administration of hydrolysed Antler to Rabbits with lanolin diet or to cholesteremia rabbits. Examination were made on the blood cholesterol value, urinary excretion of cholesterol ,cholesterol in various organs, and rabbits bred on lanolin diet were used as the control. From these experimental data, it was found that the best decholesterol action is seen in a intial added hydrolysed Antler diet.

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Enhancing the Physicochemical Properties of Sodium Iodide-based Root Canal Filling Material with Lanolin Incorporation

  • Hye Shin Park;Jongsoo Kim;Joonhaeng Lee;Jisun Shin;Mi Ran Han;Jongbin Kim;Yujin Kim;Junghwan Lee
    • Journal of the korean academy of Pediatric Dentistry
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    • v.51 no.2
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    • pp.140-148
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    • 2024
  • This study aimed to enhance the physicochemical properties of sodium iodide-based root filling materials, particularly solubility. In earlier developmental stages, the iodoform-containing paste exhibited high antibacterial efficacy but failed to meet only the solubility requirement among the ISO 6876 criteria. Therefore, this study focused on enhancing the physicochemical properties of the paste under development, particularly centering on reducing its solubility. Four experimental groups were established, including three control group. The previously developed D30 paste was named the Oil 33 group, and the control group was named the Vitapex® group. The Oil 50 group, in which the oil content was increased, and the Oil 45L group, in which lanolin was incorporated. The physical properties (solubility, pH, flowability, and film thickness) of the four pastes were evaluated according to the ISO 6876 standards. No significant differences were observed between the Oil 45L and Vitapex® groups in any of the physical property evaluations. While the Oil 33 and Oil 50 groups met the ISO 6876 standards for flowability and film thickness, the Oil 45L group met all the physical properties. However, reducing the overall oil content may be necessary to enhance the antimicrobial properties. The result of the physicochemical experiments showed that the Oil 45L group with the newly formulated composition and incorporated lanolin exhibited low solubility meeting the ISO 6876 standard of ≤ 3%. We were able to develop a paste with more stable solubility than previous iodide-based root-filling materials. Therefore, the oil content must be further adjusted to improve its antimicrobial properties. If other physical properties also meet the ISO 6876 standards and demonstrate excellent results in cytotoxicity tests, this root filling material could potentially replace existing options.

Detection of Atherosclerotic Lesion with $^{99m}Tc-LDL$ Scintigraphy ($^{99m}Tc-LDL$ (Low Density Lipoprotein)신티그라피를 이용한 동맥경화병소 진단)

  • Kim, Deog-Yoon;Koh, Eun-Mi;Woo, Jeong-Taek;Kim, Sung-Woon;Yang, In-Myung;Kim, Jin-Woo;Kim, Young-Seol;Kim, Kwang-Won;Choi, Young-Kil
    • The Korean Journal of Nuclear Medicine
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    • v.26 no.2
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    • pp.257-264
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    • 1992
  • Diagnostic approaches such as angiography, ultrasound, computed tomography and nuclear magnetic resonance have limitation for contributing to the early clinical diagnosis of atherosclerosis. Recently, $^{99m}Tc-labelled$ low density lipoprotein was developed to detect early atherosclerotic lesion by external imaging with gamma camera. To determine whether $^{99m}Tc-LDL$ scintigraphy can visualize the active atherosclerotic lesion, rabbits were injected with $^{99m}Tc-LDL$, 3 months after feeding dietary fat (lanolin) and we obtained following results. 1) Labelling efficiency of $^{99m}Tc-LDL$ was $79\sim88%$. 2) Biodistribution study of normal rabbits with $^{99m}Tc-LDL$ revealed the high activities in spleen, adrenal gland, liver, kidney which are major organs of high metabolic rate of LDL. 3) Three months after feeding lanolin, serum cholesterol was markedly increased from $74{\pm}17mg/dl$ to $979{\pm}153mg/dl$ and histologic study of aorta after sacrificing the rabbit demonstrated marked atherosclerotic changes. 4) Atherosclerotic lesion of abdominal aorta which was confirmed with histologic study could be demonstrated in $^{99m}Tc-LDL$ scintigraphy after feeding lanolin for 3 months. In conclusion, the results of this preliminary investigation suggest that it may be possible to image active atheromatous lesion with $^{99m}Tc-LDL$. It is anticipated that this promising agent may allow the in vivo monitoring of preclinical atherosclerotic lesions and may be useful to evaluate the metabolic pathway of LDL in humans.

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A Study on Development of Model Materials Showing Similar Flow Characteristics of Hot Mild Steel at Various Temperatures (고온 연강 유동특성을 상사하는 모델재료 개발에 관한 연구)

  • 이종헌;김영호;배원병;이원화
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.17 no.5
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    • pp.1161-1171
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    • 1993
  • Model materials are developed to achieve similarity of flow patterns for mild steels in forming processes at high temperatures. The model materials consist of pure plasticine and one or two additives such as resin and lanolin. To verify the similarity of flow patterns between physical modeling and compression of mild steels at high temperatures, ring and compression tests have been carried out with the developed-model materials at various strain rates, temperatures and lubricants. The test results are in good agreement with the flow patterns obtained from upsetting of a mild steel at high temperatures.

Examination of Effectiveness of Existing Wound Dressings (현재 사용 중인 상처도포제의 유효성 검정)

  • Lee, Kyu Hwa;Lee, Yong-Hwan;Song, Hyeon-Seong;Lee, Joung Goo;Yoo, Jaeryong;Ahn, Saekyul
    • Journal of Korean Society of Forest Science
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    • v.105 no.4
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    • pp.505-509
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    • 2016
  • This study was conducted to examine the effectiveness of various dressing materials applied to tree wounds in Korea. Significantly higher wound closure rates than those of controls were found when thiophanatemethyl paste (Topsin Paste$^{(R)}$) was applied to Ginkgo biloba, Zelkova serrata, and Prunus yedoensis; lanolin to Z. serrata and P. yedoensis; and tebuconazole paste (Silvacur$^{(R)}$) to P. yedoensis. However, significantly lower wound closure rates than those of controls were found when petroleum jelly (Vaseline$^{(R)}$) was applied to G. biloba, Z. serrata, and P. yedoensis. It was noted that the wounds of Z. serrata and P. yedoensis treated with petroleum jelly expanded due to the death of cambium located at the edge of the wounds. Wound closure rates applied with adhesive - non-toxic to human body (Okong bond$^{(R)}$) were also significantly lower than those of controls in Z. serrata. Pinus densiflora showed no reaction to any experimental wound dressing because of resin secreted from the exposed cambium.

Prevention of Oil Stain on Steel Induced by Fat and Oil Compounds (유지화합물에 의해 생성된 철판의 기름얼룩 방지)

  • Chung, Yeong-Jin;Nam, Chong-Woo
    • Applied Chemistry for Engineering
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    • v.5 no.3
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    • pp.419-424
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    • 1994
  • An oil stain on the steel induced by metal working oil was studied on the six kinds of fat and oil compounds(rapeseed oil, oleic acid, methyl oleate, oleyl alcohol, lauryl amino, and lanolin) by MIL-C-22235A test. The samples used for the printing on the oil stain plates were prepared by the addition of fat and oil compounds(10wt% ) and antioxidants(B. H. T, B. T, T. C. P; 0.5wt%) to base oil(spindle oil; 1.5wt% of sulfur). An analysis based on the experimental data indicated that B.T was more effective than B. H. T and T. C. P as antioxidant for inhibiting oil stains. And acid values exerted a bad influence upon the preventation of oil stains. As expected by the chemical structure of fat and oil compound, oleic acid that could react with iron ions produced more stains on the steel pannel.

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Preparation and Characterization of Durable Softener for Cotton Fiber (면섬유용 내구성유연제의 제조 및 유연특성)

  • Lee, Ae-Ri;Kim, Sung-Rae;Hahm, Hyun-Sik;Park, Hong-Soo
    • Journal of the Korean Applied Science and Technology
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    • v.20 no.4
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    • pp.341-345
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    • 2003
  • Organic acid salt of fatty polyamide (DDDT) and acrylate of fatty carbamide (DDTCA) were synthesized as a main component for the softener. O/W type non-ionic softener (NSC) was prepared by blending DDDT and DDTCA with beef tallow, lanolin anhydride. polyoxyethylene(7) stearyl ether, and polyoxyethylene(50) oleyl ether. After treatment of NSC to all cotton fabrics, the physical properties such as tear strength, crease recovery, and flexing abrasion resistance were measured. As a result of the measurement, NSC was proved to be durable non-ionic softener with good softness.

Stability and Formation Mechanism for MLV liposomes with Phospholipid Film by Use of the Microfluidizer

  • Kim, In-Young;Seo, Bong-Seok
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.22 no.2
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    • pp.99-114
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    • 1996
  • The MLV liposomes have been developed in many drugs and cosmetics fields. The phospholipid base is made from ceramides, cholesterol, cholesteryl ester, lecithin, lanolin ester, and B-sitosterol, and surfactants are made by using (PEG)n-sitosterol(n=5) and K-cetyl phosphate. We made visicles stable by passing samples through Microfludizer and croated multilamellar vesicles to make MLV liposomes similar to the structure of men's skin. In order to make MLV liposomes, we created lipid membrane films which a mixure of phospholipid base and polyol group was reacted above Tc(95$^{\circ}C$) by gelation for 3 hours. As the optimum conditions of Microfluidizer, we figured out 700 bar for the passing pressure of samples, 4$0^{\circ}C$ for its temperature, and 3 times of frequency to pass through samples. Our MLV liposomes is stable on conditions of a low temperature(5$^{\circ}C$) and a high temperature(45$^{\circ}C$), which is not to be split in a large range. We produced our own moisturizing cream which has a good affinity to skin by means of this system.

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Preparation and Characteristics of Ahcovel Type Nonionic Durable Softner (Ahcovel계 비이온성 내구유연제의 제조와 유연특성 연구)

  • Shin, Jae-Hyun;Kim, Sung-Gea;Park, Hong-Soo
    • Journal of the Korean Applied Science and Technology
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    • v.15 no.1
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    • pp.17-23
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    • 1998
  • To prepare a O/W type nonionic durable softner(ANSA), synthesized 1, 3-dihexadanoyl-2, 7-dioxy-6, 8-di(2-hexadecanoyloxyethyl)-1, 3, 6, 8-tetraazacyclodecane as the main component of softner, was blended with beef tallow, anhydrous lanolin, polyoxyethylene(20) oleyl ether, sorbitan sesquioleate, and polyoxyethylene(7) stearyl ether in various compositions. Emulsion stability of ANSA was good, and the mixed HLB value was 9.8. After the treatment of ANSA to all cotton fabrics, the physical properties such as tear strength, crease recovery, and flexing abrasion resistance were measured, respectively. As a result of the measurement, ANSA was proved to be durable softner with good softness.